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31 articles for “Phytochemical screening”
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Phytochemical Screening and Biological Activity of Pomegranate Extracts
Abstract: Pomegranates are renowned for their abundance of bioactive compounds that exhibit potent antioxidant, anti-inflammatory, and antimicrobial properties, making them a subject of growing interest in natural medicine. This study aimed to compare the biological activities of ethanolic extracts derived from different parts of the pomegranate plant—specifically, the bark, peel, and leaves. A comprehensive investigation was conducted to evaluate their phytochemical composition and assess their antimicrobial, antioxidant, and anticancer properties. The …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 64–79 Read article
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Edible Mushrooms: Management of Diabetes Mellitus and Phytochemical Screening of Agaricus Bisporus
Abstract: A metabolic disease characterized by elevated blood glucose levels; diabetes mellitus affects millions of people. If not treated on time, it causes problems, damage organs, and even life-threatening. Studies have shown that diabetes can be avoided and controlled with a healthy lifestyle that incorporates exercise and a balanced diet. While there are several synthetic medications available to treat this illness using them over an extended period of time is linked …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 1–13 Read article
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In-Silico Screening of Phytochemicals for Identification of Alternative Therapy for Thyroid Cancer
Abstract: Thyroid cancer remains a significant health concern globally, necessitating the exploration of novel therapeutic alternatives to improve treatment outcomes. This study targets COT kinase (Cancer Osaka Thyroid Kinase), a protein implicated in the progression of thyroid cancer, using molecular docking methods with various phytochemicals to identify potential therapeutic compounds. PyRx and Discovery Studio were employed to evaluate the interactions and binding affinities of a diverse set of natural compounds with …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 31–55 Read article
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Extraction and Compound Analysis of Bauhinia acuminata: Soxhlet Method and Identification
Abstract: In the present study, the extraction and compound analysis of Bauhinia acuminata using the Soxhlet method, coupled with identification techniques, were conducted. Bauhinia acuminata L., a member of the Leguminosae (Fabaceae) family in the Caesalpinioideae subfamily, is a shrub usually reaching a height of around 3 m. It is native to tropical Southeast Asia and commonly found in the tropical regions of India and China. Primarily grown for ornamental purposes, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 18–23 Read article
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Formulation and Evaluation of Betel Leaf and Clove Based Herbal Gel
Abstract: This study developed and assessed a herbal gel comprising extracts of betel leaf (Piper betle) and clove (Syzygium aromaticum) for topical use. Herbal extracts were prepared by Soxhlet extraction and analyzed for yield, phytochemical profile and total phenolic content (TPC). The phytochemicals present were alkaloids, flavonoids, tannins and phenols, and glycosides, with a greater phenolic content for clove extract. Herbal gels were prepared using Carbopol 934 and assessed for properties, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 Read article
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In Silico Screening and Molecular Docking of Cynodon dactylon phytochemicals against COPD-Associated Proteins
Abstract: Chronic Obstructive Pulmonary Disease or COPD is a pulmonary disease that obstructs airways and alveoli accompanied by respiratory issues like emphysema and bronchitis. This disease is caused mainly by inflammatory responses of the body to foreign particles that enter the respiratory path including tobacco smoke, air pollutants and irritants. The hallmark of COPD is excessive inflammation caused by imbalance in protease anti-protease activity. Proteases like elastase breakdown the ECM of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Molecular Docking Studies of Nyctanthes arbor-tristis Phytochemicals for Targeting TNF Receptor in Arthritis
Abstract: Rheumatoid Arthritis is an autoimmune disorder which results in inflammation. Tumor necrosis factor-alpha (TNF-α) is responsible for the progression of inflammatory arthritis by promoting immune cell activation and cytokine release. The present study explores the potential of bioactive compounds derived from Nyctanthes arbor-tristis (Parijat) in modulating TNF receptor activity through molecular docking. Computational methods were employed to evaluate the binding affinity of selected phytocompounds from N. arbor-tristis against the extracellular …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 11–21 Read article
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SYNTHESIS, CHARACTERIZATION AND BIOMEDICAL APPLICATIONS OF A SILVER NANOPARTICLE-COATED CHITOSAN–FUCOIDAN POLYMER NANOCOMPOSITE LOADED WITH PERSEA AMERICANA LEAF EXTRACT
Abstract: Consuming a natural composite of Persea americana (Avocado) leaf extract and a chitosan and fucoidan form a biodegradable biopolymer matrix–polymer nanocomposite with biomedical applications, this study explored a potential therapeutic method. GC-MS and UV spectroscopy were used to describe the aqueous leaf extract, which was verified by phytochemical screening to contain flavonoids, tannins, phenols, terpenoids, and alkaloids. The chitosan–fucoidan biodegradable polymer matrix served as a biocompatible stabilizing and encapsulating carrier …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Therapeutic Prospects and Comparative Bioactive Evaluation of Fenugreek Seed Extracts
Abstract: A medicinal plant with substantial therapeutic potential, fenugreek (Trigonella foenum-graecum L.) is rich in bioactive phytoconstituents. The phytochemical makeup and antioxidant properties of aqueous and methanolic fenugreek seed extracts were compared in this study. Phenolics, flavonoids, terpenoids, alkaloids, tannins, and saponins were found in both extracts, with the methanolic fraction showing greater intensity, according to preliminary phytochemical screening. The methanolic extract has higher levels of phenolic, flavonoid, and terpenoid content, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 Read article
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Chemical Composition and Antimicrobial Efficacy of Ferula persica Extracts: A Phytochemical and Bioactivity Assessment in Iraq
Abstract: The research presented in the tables focuses on analyzing the chemical content of extracts from the Ferula persica plant, a wild species in Iraq with significant medical and therapeutic importance dating back to ancient times. This study involved testing some chemical and physical properties of the alcoholic extract of the plant's aerial parts and evaluating its antimicrobial activity, specifically against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). The …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 10–22 Read article
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Assessment of Diuretic Activity of Hydroalcoholic Extract of Matricaria Chamomilla (Linn.) and Its Phytochemical Analysis with Emphasis on Toxicology
Abstract: While the traditional medicines are derived from medicinal plants, minerals and organic matter, the herbal drugs are prepared from medicinal plants only. This current research work will be very beneficial in figuring out the Matricaria chamomilla leaves extract diuretic effect by determining the ions and electrolyte excreted by the animals using ion selective channel inhibition. The phytochemical screening results revealed that the after which it was observed whether the alkaloids …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Review on Elaeocarpus Ganitrus (Rudraksha)
Abstract: The seed of Elaeocarpus Ganitrus, also known as Rudraksha, is renowned for its electromagnetic characteristics. Recent scientific research has demonstrated that this seed possesses natural electromagnetic properties which can effectively treat various chronic diseases. This study focuses on the phytochemical screening and thin layer chromatographic analysis of the extract obtained from Elaeocarpus Ganitrus seeds, which belong to the Elaeocarpaceae family. Bombay, and is commonly grown as an ornamental tree in …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 8–15 Read article
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Exploring Chocolate’s Potential: A Review of Its Role in Drug Delivery and Health Benefits
Abstract: The abstract explores the versatile nature of chocolate, highlighting its role as a medium for drug delivery systems due to its resistance to microbial growth and rich nutritional profile. Medicated chocolate, infused with drugs, offers a palatable solution to enhance patient compliance, particularly among children, while stimulating serotonin production for added therapeutic benefits. Cocoa, abundant in polyphenols, contributes to chocolate's health advantages, including cholesterol reduction and cardiovascular health. Scientific evidence …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 16–24 Read article
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Exploring the Bioactive Potential of Himalayan Lichens: Phytochemical and Antimicrobial Profiling of Xanthoparmelia tinctina and Pyxine subcinerea Extracts
Abstract: The symbiotic association that develops between cyanobacteria, algae, and fungi results in the composite organism known as lichens, which has traits similar to those of plants but differs in its separate parent organisms. Lichens can have a variety of morphological characteristics, including foliose structures that resemble flat leaves, crustose structures that resemble flake crystals, fruticose branches that have short, leafless branches, and leprose-powder-like appearances. Due to their therapeutic potential, lichens …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 21–28 Read article
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In Vivo Hypoglycemic Activity of Aqueous Leaf and Root Extracts of Macaranga Barteri Müll. Arg. (Euphorbiaceae) In Swiss Albino Mice
Abstract: Background: Macaranga barteri Müll. Arg. is a perennial plant in the family Euphorbiaceae and is used in African traditional medicine for the management of several ailments, including diabetes. Although the leaves and stem bark have been studied for various pharmacological activities, little is known about the therapeutic value of the roots. Objective: This study evaluated the in vivo hypoglycemic activity of aqueous leaf and root extracts of M. barteri in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 Read article
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A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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In-Silico Studies of Phytochemicals from Allium sativum with H5N1 Protein in Avian Influenza
Abstract: Allium sativum or garlic is a medicinal plant that is reported for its applications in many biological activities, such as its antiviral, antidiabetic, and anti-inflammatory properties, etc. In this paper, the focus has been the identification of potential phytochemicals that can be extracted from Allium sativum that can act as a candidate for drug formation that possesses the capability to inhibit the H5N1 Avian Influenza, a type of highly pathogenic …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 50–60 Read article
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In-silico Approach of Few Selected Phytoconstituents on Newer Cancer Targets
Abstract: Background: Cancer’s high death rates are mainly due to, drug resistance and unmet medical demands. It necessitates novel anticancer medications. AI tools aid in efficient and faster drug discovery by analyzing data, modeling processes and optimizing pipeline stages. Aim: The aim of this present study is to evaluate phytoconstituents against novel and newer cancer targets. Methodology: The ligands Daidzein, Resveratrol and Genistein were targeted against the Glutamate dehydrogenase (PDB ID …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 12–17 Read article