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550 articles for “HIV-1 Integrase” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Lamivudine And Dolutegravir Simultaneous Dosage Forms Determined and Validated Using The RP-UPLC Method
Abstract: RP-UPLC has been used to produce a straightforward, precise, and accurate approach for the simultaneous estimation of dolutegravir and lamivudine in a pharmaceutical dose form. A HSS C18 column of 2.8 x 50 mm and featuring particles with a size of 1.6 μm was used to process the chromatogram. A mixture of 70:30 Buffer Na2HPO4 and methanol made up the mobile phase, which was pushed across the column at a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 5–13 Read article
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Hidradenocarcinoma: A Rare Skin Disease
Abstract: Hidradenocarcinoma (HAC) also known as ‘‘sweat gland tumor” is an aggressive, uncommon, highly malignant, adnexal tumor derived from the intradermal duct of eccrine sweat glands. It is said to be aggressive as it has a high risk of local recurrence (50%–75%) and a high potential to metastasize to nearby lymph nodes or to other distant sites. Hidradenocarcinoma has other recognized variants which are known by different names such as Malignant …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 1–12 Read article
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A Study on Determination of Seismic Susceptibility in Existing Buildings in Ward No-18 of Dhaka North Using Rapid Visual Screening (RVS) Method
Abstract: The research work presents a comprehensive analysis of the Rapid Visual Screening (RVS) method applied to 200 buildings in Ward No. 18 of Dhaka North City. The study focused on assessing the seismic vulnerability of these structures, categorizing them into damage grades based on the RVS evaluation. Strikingly, the findings revealed that 191 out of the 200 buildings were classified as damage grade 5, signifying severe structural deficiencies. In contrast, …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 28–37 Read article
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Remediation of Condemn Oil Polluted Loamy Soil Using Azadirachta Indica (Neem)
Abstract: The remediation of condemn oil polluted loamy soil using neem (azadirachta indica) was investigated. The neem leaves came from Akpugo in the southeast Nigerian state of Enugu State's Nkanu West local government area. The leaves were dried at room temperature and subjected to grinding machine to obtain the powdered form of the dried leaves that serve as treatment to remediate condemn oil polluted loamy soil. Three masses 5g, 10g and …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 21–27 Read article
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Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
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A Comparative Analysis of Factors Contributing to Relapse in Alcohol and Opioid Dependence Among Patients Admitted to Selected Hospitals in Ludhiana, Punjab.
Abstract: Introduction: Substance abuse involves the dangerous or detrimental use of psychoactive substances, such as alcohol and illegal drugs. The use of these substances can result in dependence syndrome, which encompasses a range of behavioral, cognitive, and physiological effects that arise from ongoing substance use. Objectives: This study was carried out to examine the factors linked to relapse in alcohol and opioid dependence among patients admitted to selected hospitals in Ludhiana, …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Exploring Muscle Energy Technique as A Physiotherapeutic Intervention for Peripheral Facial Palsy: A Pilot Report
Abstract: Background: Peripheral facial palsy results from damage to the peripheral branches of the facial nerve, often presenting as a sudden weakness in the muscles on one side of the face. Research on the application of muscle energy technique (MET) for treating this condition is scarce. Therefore, the aim of this study was to assess the effectiveness of MET in the treatment of peripheral facial palsy. Methods: 15 patients suffering from …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 21–29 Read article
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An Evaluation of the Impact of a Nurse-Led Program on Knowledge and Practices Related to Needle Stick Injury Prevention Among 2nd Year B.Sc. Nursing Students at the College of Nursing, PT. B.D. Sharma PGIMS, Rohtak
Abstract: Healthcare workers and nursing students frequently face accidental occupational exposures while caring for patients, with needle stick injuries being the most common form of exposure in healthcare settings. These injuries pose a significant risk of infections. This study aimed to evaluate the awareness and practices related to the prevention of needle stick injuries among second-year B.Sc. Nursing students, assess the effectiveness of a nurse-led intervention in enhancing their knowledge and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 28–66 Read article
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Air Pollution and Immune Disorders in Women from Urban Punjab: A Clinical and Epidemiological Study
Abstract: Background: Urban Punjab, particularly cities like Ludhiana, Amritsar, and Jalandhar, experiences some of the highest air pollution levels in India due to industrial activity, vehicular emissions, and agricultural practices. Despite this, gender-specific health impacts—especially related to immune function—remain inadequately studied. Objective of the study is to investigate the relationship between air pollution exposure and immune-related disorders in women residing in urban Punjab. A cross-sectional study was conducted from 2022 to …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 36–40 Read article
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Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
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Spatial Distribution and Species Diversity of Marine Bibalves Along the Rocky Intertidal Zone of Veraval, Gujarat, India.
Abstract: The rocky intertidal shoreline of Veraval, located along the Saurashtra coast of Gujarat, serves as a vital habitat for various marine organisms due to its unique composition of rocky- sandy patches and tidal pools. This study was undertaken to evaluate the diversity and spatial distribution of marine bivalves at the Jaaleshwar coast (20º 54’ 36.210’’ N, 70º 21’ 09.090’’ E). Field observations were carried out over nine months from July …
Published in International Journal of Marine Life · Vol. 3, Issue 1, 2026 · pp. 25–30 Read article
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The Hidden Struggle: Premenstrual Depression its Impact on Women’s Health and Management Strategies: A Narrative Review.
Abstract: Background: Premenstrual depression, including Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), represents a significant yet underrecognized contributor to women’s mental health burden. Hormonal fluctuations during the luteal phase interact with neurotransmitter systems, particularly serotonin and GABA, leading to affective and somatic symptoms that impair daily functioning. Objective: This systematic review synthesizes evidence on the prevalence, pathophysiology, psychological impact, and management strategies of premenstrual depression among reproductive-aged women, with particular …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 · pp. 21–32 Read article
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Enhancing the Strength of Black Cotton Soil with Enzyme and Industrial Waste
Abstract: Expansive soils are troublesome and prone to ground movements, which can cause substantial damage to underlying buildings as well as a loss in bearing capacity. Moisture fluctuation activates the expansive character of soils, causing it to swell and shrink. This has long been known in geotechnical engineering. To treat expansive soils, a variety of stabilizing additives such as lime, cement, and fly ash have been employed. In recent years the …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 1–11 Read article
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Incidence of Salmonella spp., Klebsiella spp., Proteus spp. and Two Micronutrients (Zinc and Iron) Present in Poultry Feeds Collected from Sokoto, Nigeria
Abstract: Mostly, poultry quality is determined by its feed. Thus, in this time of ravaging pollution and infectious diseases monitoring of quality of products related to poultry is eminent. This study aimed at determining the incidence of some microbes and micronutrients (zinc and iron) in poultry feed in Sokoto, Nigeria. Standard methods and materials of analytical grade were used. Zinc and iron micronutrients were determined in feed and egg using atomic …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 31–38 Read article
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Knowledge and Perception of the Ill Effects of Cosmetics Among Late Adolescent Girls
Abstract: The current research focused on examining the knowledge and attitude towards the negative effects of cosmetics among late adolescent girls studying at DM WIMS Pharmacy College in Meppadi, Wayanad. The study aimed to evaluate the level of knowledge and attitude toward the harmful effects of cosmetics among these girls and explore any potential associations between their knowledge, attitude and selected socio-demographic variables. To conduct the study, a quantitative approach using …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 15–20 Read article
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Quality of Sleep Among Patients with Chronic Renal Failure
Abstract: Renal failure is the partial or complete impairment of kidney function. Inability to eliminate metabolic waste products and water, along with functional disruptions in all bodily systems, result in the condition known as renal failure. Renal failure can be categorized as either acute or chronic. Chronic renal failure refers to the gradual and irreversible deterioration of the nephrons in both kidneys. It is characterized by either kidney damage or a …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 22–28 Read article
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A Study to Evaluate the Effectiveness of a Structured Teaching Program on the Knowledge and Practice of Road Traffic Accident Prevention Measures Among Teenagers
Abstract: An investigation to evaluate the impact of a structured educational program on the understanding and implementation of strategies for preventing road traffic accidents among teenagers. Introduction: Accident is an accidental injury, passing or property harm happening in a grouping of occasions. Accidents don't simply occur; they are neglectfulness, indiscretion, carelessness, and flashing absence of focus. Accidents have turned into a significant reason for dismalness and mortality, particularly among the grown-ups …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 29–40 Read article
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Usefulness of Video Assisted Education Programme Concerning Awareness on Management of Selected Nutritional Deficiency Disorders Among Mother of Adolescent Girls at Selected Rural Area of Kolar Taluk
Abstract: Background: With an estimated 190 million adolescents, 22% of whom are girls, India has one of the fastest increasing youth populations in the world. Adolescence, as defined by the WHO, is the period between the ages of 10 and 19, which provides a window of opportunity for improving nutritional status and reversing unhealthy eating habits. A growth spurt, or a time when growth is incredibly rapid, is what defines adolescence. …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 1–5 Read article
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Effect of Initiation of Breast-Feeding on Maternal-Newborn Attachment: A Cross-Sectional Study
Abstract: Introduction: Breastfeeding is the best approach for meeting an infant's psychological and physiological needs. The importance of breastfeeding is best understood in light of the fact that early breastfeeding initiation and skin-to-skin contact soon after birth are essential for a newborn's survival. The connection between a mother and her infant plays a vital role in a child's growth and maturation. Hence, a research investigation was carried out to analyze how …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 1–9 Read article