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Research and Reviews: A Journal of Pharmacology Original Research

Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats

  1. Ravi Babu.Birudu Acharya Nagarjuna University, Guntur
  2. Jagadish Naik Acharya Nagarjuna University, Guntur
  3. Awais Ali Abdul wali Khan University
  4. Waseef Ullah Abdul wali Khan University
  5. Syed Luqman Ali Abdul wali Khan University
  6. Majda Badaoui Cadi Ayyad University
  7. Hajar Arizada Cadi Ayyad University

Abstract

The anti-oxidant system present in our body prevents against the free radicals. Anti-oxidants were glutathione peroxidise,serum catalase,vitamin E, ascorbic acid and superoxide. In our study the plant extract of Passiflora foetidae were used to estimate the antioxidant levels in diet-induced diabetic rats. The mean of glutathione peroxide of normal rats was 92.98±1.65. "The mean of diet-induced diabetic rats was 152.50 ± 1.92*. Diabetic rats treated with sitagliptin and vildagliptin had mean values of 121.75 ± 4.33* and 124.90 ± 2.85*, respectively. The mean values of Ascorbic acid in normal rats was 0.50±0.27.Diet- induced diabetic rats have ascorbic acid mean 3.50±0.28. The normal rat’s mean of serum catalase was 112.55±1.76.Diet induced rats have mean a value of 125.78±1.96*.This value is significant. Diet-induced diabetic rats treated with a standard drug have a mean of 121.38 ± 1.68*. Diabetic rats treated with plant extracts of PSF (Passiflora foetida leaf) exhibit mean values of 123.47 ± 1.67*, 119.27 ± 4.38*, and 113.07 ± 3.82. The outcomes of our study indicate that both plant extracts and standard drugs improve the anti-oxidant levels.

Keywords

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