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96 articles for “anti-inflammatory compounds”
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Solanum viarum Dunal: Ethnomedicinal Importance, Phytochemical Profile and Pharmacological Potential — A Comprehensive Review
Abstract: Solanum viarum Dunal, commonly known as tropical soda apple or Sodom apple, is a medicinally important plant belonging to the family Solanaceae. The plant has been widely utilized in traditional medicine systems for the treatment of fever, cough, skin disorders, inflammation, gastrointestinal ailments, and microbial infections. The present review comprehensively summarizes the ethnomedicinal importance, phytochemical profile, pharmacological activities, and pharmaceutical significance of S. viarum. Literature reports indicate that the plant …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 3, 2026 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Design, Synthesis, and Evaluation of Novel Quinazoline Derivatives as Anti-Inflammatory Agents
Abstract: Novel quinazoline derivatives are well-known heterocyclic scaffolds that are renowned for having a wide range of biological functions. A new quinazoline derivative was synthesized from anthranilic acid through a multi-step sequence involving amide formation, cyclization, and aromatic group substitution. The structure of the methoxy- and chloro-substituted final compound was confirmed by IR and 1H NMR spectroscopy. Evaluation of synthesized molecules anti-inflammatory activity using paw edema caused by carrageenan paradigm in …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 01–09 Read article
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Review on Spirulina ( Green Alage)
Abstract: Spirulina is an edible blue-green algae that is a plant protein source. In recent years, its health benefits have attracted scientific attention, including micro-level examinations of the algae's bioactive components. As proof of concept, investigations conducted in vitro, in vivo, and ex vivo have shown how spirulina works and how it affects immunity. Spirulina has been used as a whole food and as a nutritional supplement for many years. It …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article
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A Comprehensive Study of Nutrients Food in Nutraceuticals: Plant Extracts, Vitamins, Minerals, and Phytochemicals
Abstract: Nutraceuticals are biologically active substances obtained from food sources that offer health benefits beyond their basic nutritional value. They include plant extracts, vitamins, minerals, and phytochemicals, each of which plays a key role in supporting health, preventing disease, and optimizing physiological functions. This review examines the role of these nutrients in nutraceutical products, with a particular focus on their mechanisms of action, therapeutic effects, and potential clinical applications. Plant extracts, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 14–22 Read article
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Synthesis, spectroscopic, crystal structure, Hirshfeld surface, computational, and biological investigations on Isophorone derivatives: 3-(3,4-dimethoxystyryl)-5,5-dimethylcyclohex-2-en-1-one
Abstract: FT-IR, 1H NMR, and 13C NMR spectroscopy were among the spectroscopic methods used to synthesize and analyze 3-(3,4-dimethoxystyryl)-5,5-dimethylcyclohex-2-en-1-one, a new isophorone derivative. Single-crystal X-ray diffraction (SCXRD) was used to determine the crystal structure, which showed that the molecule crystallizes in a monoclinic system (space group P121/c1) with packing configurations and intermolecular interactions. To learn more about the non-covalent interactions influencing the crystal packing, Hirshfeld surface analysis was used. In order …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 51–69 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Emerging Trends in Horticultural Crops: Role of Date Fruit in Promoting Urinary and Kidney Health
Abstract: Dates, or Phoenix dactylifera L., have been widely consumed in different cultures, both as a food source and for their health benefits. Whereas dates have been reported extensively to improve cardiovascular, gastrointestinal, and metabolic function, their role in urinary tract and renal health has received lesser attention in mainstream nutritional sciences. This review systematically evaluates and synthesizes the current literature on the potential effects of dates to promote urinary health …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 1, 2026 · pp. 24–32 Read article
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Review on Formulation and Evaluation of Herbal Gel of Moringa oleifera and Aloe vera for management of acne
Abstract: Acne vulgaris is a prevalent chronic inflammatory disorder of the pilosebaceous units, characterized by excessive sebum production, follicular hyperkeratinization, bacterial colonization, and inflammation. Conventional therapies often result in side effects and the development of drug resistance, prompting the exploration of natural alternatives. This review highlights the potential of Moringa oleifera and Aloe vera in acne management via topical drug delivery systems (TDDS). Moringa oleifera is rich in bioactive compounds such …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 10–16 Read article
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Comprehensive Evaluation of Herbal Plants for Cancer Prevention
Abstract: Since cancer continues to be a major cause of morbidity and death globally, effective prevention measures are desperately needed. As the world’s cancer burden increases, interest in alternative cancer prevention methods, particularly the use of herbal medicine, is also increasing. With their rich history and diverse phytochemical composition, medicinal plants provide a great opportunity for the development of disease prevention strategies. This review explores the potential of various plants, including …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 01–07 Read article
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Turmeric as a Key Ingredient in Cosmeceuticals: New Scientific Evidence
Abstract: Turmeric (Curcuma longa), particularly its active compound curcumin, is gaining recognition in cosmetics and medicine for its therapeutic properties. Its antioxidant, anti-inflammatory, and antimicrobial effects make it a popular skincare ingredient, helping reduce inflammation, brighten skin, and fight aging. In addition to treating dandruff and promoting hair growth, Turmeric is also good for scalp health. Curcumin increases the body's antioxidant defenses. Inhibits inflammation and anti-oxidants. Curcumin, a powerful compound found …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 28–36 Read article
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Pharmacokinetic and Pharmacodynamic Studies of Black Seed Derived Compound
Abstract: Black seed (Nigella sativa) has been celebrated for centuries for its remarkable therapeutic properties. Among its bioactive compounds, thymoquinone (TQ) has gained significant attention in pharmacological research due to its diverse health benefits. This review delves into the pharmacokinetic (PK) and pharmacodynamic (PD) properties of black seed compounds, with a particular emphasis on TQ, the most extensively studied component. The PK of TQ includes the parameters of absorption, distribution, metabolism, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 36–43 Read article
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Protective Effects Of Curcumin Against Osteoporosis And Its Molecular Mechanism
Abstract: One of the most prevalent metabolic disorders is osteoporosis (OP), which primarily affects postmenopausal women and the elderly. It is often associated with gradual loss of bone density, ongoing destruction of bone microstructure, and increased risk of osteoporosis. Pharmacotherapy is the primary approach for treating and preventing osteoporosis. However, persistent medication therapy invariably results in drug responses and particular adverse effects. Therefore, scientists continue to search for new monomeric compounds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 16–23 Read article
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Formation, Organic Investigation, Fluorescence Study of New Cyclic Derivatives of Thiophane-Triazole Compounds
Abstract: Azo compounds are used as intermediates in the preparation of many well-known and diverse organic derivatives. Cyclical or related azo derivatives, such as triazoles and thiophenes, possess useful applications in medicinal and pharmaceutical chemistry. Thiophene compounds and their derivatives have demonstrated a variety of biological activities, including antibacterial, antifungal, anti-tuberculosis, anti-inflammatory, analgesic, sedative, and hypnotic properties, immunosuppressive, and antihypertensive properties. Furthermore, thiophene derivatives can be used in the treatment of …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 3, 2025 · pp. 1–13 Read article
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A Comprehensive Review on Coumarin Derivatives
Abstract: Coumarins are naturally occurring compounds found in plants, fungi, and microorganisms with diverse bioactivities. They have antithrombotic, anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, and neuroprotective properties. Extracting coumarins, using methods like maceration and microwave- assisted extraction, is crucial for their applications. However, safety and toxicology are important, especially in pharmaceuticals, cosmetics, and food additives. Consuming moderate amounts of coumarin-rich foods is generally safe, but excessive intake raises concerns about hepatotoxicity and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 72–80 Read article
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Studies on the antioxidant content and antimicrobial activity of cucumber (cucumissativus) peel collected from bagmari, kolkata, west bengal, india
Abstract: Cucumber (Cucumis sativus) is widely consumed across the globe, yet its peels are commonly discarded as waste, despite possessing a wealth of bioactive compounds. Recent studies have highlighted that these peels contain substantial amounts of antioxidants, antibacterial, anti-inflammatory, and anti-carcinogenic properties, making them a promising candidate for value-added applications. In this study, methanolic extracts (80% v/v) of cucumber peels were systematically analyzed to assess their total phenolic content (TPC), total …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Studies on the Antioxidant Content and Antimicrobial Activity of Cucumber (Cucumis sativus) Peels Collected from Bagmari, Kolkata, West Bengal, India
Abstract: Cucumber (Cucumis sativus) is widely consumed across the globe, yet its peels are commonly discarded as waste, despite possessing a wealth of bioactive compounds. Recent studies have highlighted that these peels contain substantial amounts of antioxidants, antibacterial, anti-inflammatory, and anticarcinogenic properties, making them a promising candidate for value-added applications. In this study, methanolic extracts (80% v/v) of cucumber peels were systematically analyzed to assess their total phenolic content (TPC), total …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 · pp. 6–14 Read article
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Exploring the Botanical and Pharmacological Significance of Aristolochia rotunda Linn (Zarawand Mudahraj): Traditional Uses, Habitat, and Bioactive Potential
Abstract: The plant Aristolochia rotunada Linn (Zarawand Mudahraj) is a member of the Aristolochiaceae family. Its rhizomes are the most valuable portion utilised in the pharmaceutical industry, mostly because of their abundance in bioactive compounds. The medicinal plant Aristolochia rotunda Linn exhibits a spectrum of pharmacological activities essential for combating hyper-uricaemia-induced inflammation. Its anti-inflammatory effects are mediated by inhibiting TNF-α, IL-1β, IL-8, and NF-κB p65 protein expression, crucial in synovial tissue. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 33–39 Read article
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A Traditional Indian Unani Dynamic Drug Amla (Emblica Officinalis) And Its Unani Pharmacological Activities In The Light of Recent Experimental Studies: A Comprehensive Review
Abstract: Since ancient times, plants have been essential to human development, serving as a primary source of natural remedies. The challenges associated with producing synthetic medications, along with their potential side effects and high costs, have driven researchers around the world to focus on the study of medicinal plants. In recent years, numerous publications have highlighted the role of plant-derived bioactive compounds in treating a wide range of human ailments, underscoring …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 21–29 Read article