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Emerging Trends in Chemical Engineering Review Article

Formation, Organic Investigation, Fluorescence Study of New Cyclic Derivatives of Thiophane-Triazole Compounds

  1. Sarah Mohammed Abed Alwan Chemistry Field, Holy Karbala Education Directorate
  2. Nagham Mahmood Aljamali2 Department of Chemistry, Synthetic Organic Chemistry

Abstract

Azo compounds are used as intermediates in the preparation of many well-known and diverse organic derivatives. Cyclical or related azo derivatives, such as triazoles and thiophenes, possess useful applications in medicinal and pharmaceutical chemistry. Thiophene compounds and their derivatives have demonstrated a variety of biological activities, including antibacterial, antifungal, anti-tuberculosis, anti-inflammatory, analgesic, sedative, and hypnotic properties, immunosuppressive, and antihypertensive properties. Furthermore, thiophene derivatives can be used in the treatment of gastrointestinal disorders, diabetes prevention, and antioxidant activities. Most thiophene and triazole derivatives are of the most importance because they form part of the structure of some important medical compounds, such as drugs used for anesthesia, muscle relaxation, and sedation in animals. They are also used as anxiolytics and muscle relaxants. In this study, and in continuation of the work of previous researchers, we have prepared several cyclic compounds of thiophene and triazole, and they were linked to other rings, as well as linked to azo groups by forming the carbanion ion and attacking the azo group through the coupling reaction, and then the compounds were identified by spectroscopic means and other applied studies to know the effectiveness of the prepared compounds like fluorescence study and measurements of absorption and emission of molecules in optical analysis.

Keywords

References (47)

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