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213 articles for “AI in Pharma”
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Nanotechnology meet phytomedicine towards smarter drug delivery system.
Abstract: Using bioactive substances derived from plants, or phytomedicine, has long shown promise in treating a variety of illnesses with fewer adverse effects than synthetic medications. Nevertheless, a lot of phytochemicals have issues with inadequate targeting in vivo, low bioavailability, poor solubility, and chemical instability. By enabling encapsulation, controlled release, targeted delivery, and stimuli responsive behavior, nanotechnology provides effective tools to get around these restrictions. This review examines the intersection of …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 46–53 Read article
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Hakim Ismail Jurjani (1042–1137 AD): Life, Works, and Medical Legacy
Abstract: Hakim Ismail Jurjani, also known as Seyyed Isma’il Jorjani, was among the most distinguished physicians and scholars of medieval Persian medicine whose contributions significantly influenced the development of Greco-Arab and Unani medical traditions. His monumental encyclopedia, Zakhīra Khwārazmshāhī (Treasure of the Khwarazm Shah), is regarded as one of the greatest medical compilations of the Islamic Golden Age and represents a landmark in the evolution of Persian scientific literature. Unlike earlier …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle weakness. This protein is seen in sarcolemma, Z disks in skeletal muscles, hemidesmosomes in skin and cardiac muscles giving stability to cytoskeleton, playing a crucial role in neuromuscular transmission …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 22–34 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Hydro-alcoholic Extract of Herbal Formulation and Evaluation of Papaya leaf And Orange Peel for treatment of Dengue Fever
Abstract: The fastest-spreading viral disease in the world is dengue contamination, which is spread by mosquitoes. Carica papaya leaf juice aids in raising the platelet count, and it occurs primarily in tropical and subtropical countries. The primary goal of this study is to inform medical experts about the use of Carica papaya leaf extract formulations (SYRUP) to treat dengue fever, a potentially fatal illness. Approach: To cure this illness, a water …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 23–33 Read article
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Advances in Analytical Chemistry Research Methodology: Trends and Applications
Abstract: Analytical chemistry is critical to scientific study because it allows for the accurate identification, measurement, and characterization of chemical compounds. Recent advances in methodology have improved accuracy, sensitivity, and efficiency, with techniques such as High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Mass Spectrometry (MS), and Nuclear Magnetic Resonance (NMR) spectroscopy transforming analytical procedures. The combination of Artificial Intelligence (AI) and Machine Learning (ML) has enhanced data processing, pattern recognition, and …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 2, 2025 · pp. 10–18 Read article
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Evaluating the Impact of the Valsalva Maneuver on Pain Relief During Intravenous Cannulation in Patients at Selected Hospitals in Tirupati, Andhra Pradesh
Abstract: Pain can be defined as an unpleasant tactile sensation, arousing sensory experience, and an emotional response that is linked to any type of tissue, cell, or skin damage. Pain is a very common and a primary reason for which people seek health care. Among all the non-pharmacological methods for pain relieving, the Valsalva maneuver is one of the methods which is found effective in reducing the level of pain a …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article
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Horizons in Neuralgia Care: Addressing Unmet Needs and Future Prospects
Abstract: Neuralgia refers to intense, sharp, and often chronic pain resulting from damage or irritation to nerves. It is typically characterized by sudden, shooting pain along the course of a nerve, significantly impairing daily functioning and impacting both physical and emotional well-being. Given its intensity and chronic nature, neuralgia presents a complex challenge in clinical management, emphasizing the importance of timely diagnosis and effective intervention to improve patient outcomes. This comprehensive …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article
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Iota carrageenan, a Sustainable polymer transformed into a nanogel formulation, by using environment friendly method for antitumor action
Abstract: In the pharmaceutical field, the utilization of polymers, both in their natural form and through chemical modifications, holds immense importance. In this context, a novel and eco-friendly method for the synthesis of nano carrageenan-based polymers has been developed. The efficacy of carrageenan in this domain is attributed to its crosslinking and biological properties, which are largely influenced by its sulfate ion content. This study aims to formulate nanogels via a …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 881–889 Read article
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In Silico Molecular Docking Studies of Phytocompounds from Melissa officinalis Against MPXV Poxin Target
Abstract: Objectives: This study aimed to evaluate the inhibitory potential of phytocompounds of Melissa officinalis against the MPXV poxin protein target, a key virulence factor in monkeypox infection. Methods: Molecular docking performed using PyRx, a virtual screening software, was conducted to predict the binding affinities of the compounds to MPXV poxin. Prior to docking, the compounds were subjected to comprehensive analysis, including Lipinski's rule of five, evaluation of physicochemical properties, pharmacological …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 25–38 Read article
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A Research Study on Navigating Medication Risks Through MFRS (Medication Fall Risk Score and Evaluation Tool) and DART (Drug Associated Risk Tool) Among Patients with Polypharmacy
Abstract: Background information: The advancements in medical science continue, but the safety of medication usage is still a question mark and has become a crucial area for researchers to focus on. In the need of the above, various scoring systems and tools have been developed in pharmacy practice research. Prior to the present work, we did a systematic review and meta-analysis and identified two such tools: the medication fall risk score …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 1–13 Read article
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A study on Public Perception and self-medication practices with Over-the-counter (OTC) Drugs
Abstract: Over-the-counter (OTC) medications are commonly used by individuals for self-medication due to their easy availability and the general belief that they are safe. However, misuse can lead to negative health outcomes such as adverse reactions, drug interactions, and delays in seeking professional medical care. In a country like India, where enforcement of drug regulations can vary and socioeconomic factors play a major role, the practice of self-medication is especially widespread. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 01–07 Read article
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A Review Article on Oroxylum indicum: A Versatile Medicinal Tree
Abstract: Oroxylum indicum, commonly known as the Indian trumpet tree or Shyonaka, is a medicinal plant belonging to the Bignoniaceae family. It is widely used in traditional medicine systems such as Ayurveda for treating various ailments including neurodegenerative diseases, cardiovascular conditions, arthritis, hepatitis, malignancies, diarrhea, fever, and jaundice. The plant's therapeutic properties are primarily attributed to its rich content of bioactive flavonoids, which exhibit notable anti-cancer, anti-inflammatory, and analgesic effects. Found …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 Read article
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Managing Chronic Diseases: Diabetes Mellitus
Abstract: Diabetes mellitus is one of the most prevalent chronic non-communicable diseases worldwide and represents a major public health challenge due to its long-term complications, increasing prevalence, and economic burden on individuals and healthcare systems. It is distinguished by chronic hyperglycemia brought on by deficiencies in either insulin action or secretion, or both. Diabetes causes increasing harm to several organ systems, including the kidneys, eyes, neurological system, and cardiovascular system, if …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Ligand Based Drug Virtual Screening in Computer Aided Drug Design: A Review
Abstract: Computer-Aided Drug Design (CADD) has revolutionized the drug discovery process by providing efficient and cost-effective methods for identifying potential drug candidates. Within CADD, ligandbased virtual screening techniques play a pivotal role in the early stages of drug discovery. This review provides a comprehensive overview of ligand-based drug virtual screening, focusing on its principles, applications, challenges, and future directions. Fundamentals of ligand-based virtual screening, including pharmacophore-based methods, similarity searching, and machine …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
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Pharmacokinetic and Pharmacodynamic Studies of Black Seed Derived Compound
Abstract: Black seed (Nigella sativa) has been celebrated for centuries for its remarkable therapeutic properties. Among its bioactive compounds, thymoquinone (TQ) has gained significant attention in pharmacological research due to its diverse health benefits. This review delves into the pharmacokinetic (PK) and pharmacodynamic (PD) properties of black seed compounds, with a particular emphasis on TQ, the most extensively studied component. The PK of TQ includes the parameters of absorption, distribution, metabolism, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 36–43 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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An Effective & Novel Approach as Gastro-retentive Drug Delivery Systems
Abstract: Researcher’s curiosity about gastro-retentive drug delivery system increased so high in recent years because of its excellent drug releasing properties to the target site. The delivery system's residence time in the stomach can be extended with the usage of gastro-retentive drug delivery system by using a number of natural and synthetic polymers such as guar gum, hydoxy propyl methyl cellulose which can be used to improve the bioavailability of a …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 47–54 Read article
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Computational Biomodeling: Transforming Drug Design with Advanced Simulations
Abstract: Computational biomodeling has emerged as a transformative approach in the field of drug discovery, significantly enhancing the efficiency and precision of identifying and optimizing potential drug candidates. This article explores the various computational techniques utilized in drug design, including molecular docking, molecular dynamics (MD) simulations, free energy calculations, and virtual screening, and examines how these methods collectively contribute to the drug development process. The integration of these advanced simulations allows …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 24–29 Read article
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Recent Trends in Ocular Drug Delivery: Challenges and Approaches
Abstract: Drug topically regulation can be accessed most easily in the eye. When given topically as eye drops, medication ocular bioavailability is quite low. Drug entry into specific ocular locations is complicated by the complex anatomy and physiology of the human eye. Research has long been interested in the topical administration of successful treatments. To provide a suitable ocular penetration and extend the duration of drug residence is their challenging task. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 22–38 Read article