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675 articles for “Novel”
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Zebrafish in Drug Research: Decoding Biological Mechanisms and Finding Novel Therapeutic Targets
Abstract: The zebrafish, scientifically known as Danio rerio, is a powerful model organism in biological research because of its favorable traits, which include rapid development, genetic tractability, and transparent embryos. Zebrafish were first identified for their use in studies of vertebrate development, but they have since spread to a variety of disciplines, such as pharmacology, clinical research as a disease model, and most notably, drug development. Zebrafish have emerged as a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 · pp. 1–8 Read article
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Novel approaches to the Design and Optimization of Universal Shift Register with Reversible logic
Abstract: Reversible logic is gaining importance in new multi-disciplinary fields, such as quantum computing, low-power computing, and even nanotechnology. The study of reversible gates has quickly evolved as a distinctive area of research as a result of the new developments aimed at fully utilizing resources and performing operations without any loss of information. With chip integration, these USRs, or Universal Shift Registers, have now become fundamental sequential components needed in various …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 3, 2025 · pp. 21–28 Read article
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IoT Network Security Employing KVS Approach: Novel Approach to IoT Security with B-Cell Inspired Models Implemented using Artificial Intelligence
Abstract: The Internet of Things (IoT), which links billions of devices that gather, analyse, and send data, is growing quickly. Although there are many benefits to this interconnection, there are also serious security risks. Conventional security measures frequently struggle to keep up with the dynamic and diverse nature of IoT environments. Innovative security ideas are being investigated in response, and the B-Cell concept, also known as the Kutubuddin Vahida Sultana (KVS) …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 3, 2025 · pp. 36–46 Read article
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A Novel Mathematical Exploration of Fractal Dynamics in Hyperbolic Spaces
Abstract: This research paper presents an original study on the behavior, generation, and properties of fractal structures within hyperbolic geometry. Unlike classical Euclidean fractals, hyperbolic fractals demonstrate accelerated boundary complexity and distinct scaling symmetries due to the curvature of the underlying space. The paper proposes new iterative models, analyzes geometric invariants, and explores potential applications in data visualization, network science, and theoretical physics. This research paper conducts an in-depth investigation into …
Published in Recent Trends in Mathematics · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Analysis of Machine Learning in Metal Processing: A Novel Prospect
Abstract: Metal is processed by a wide range of procedures, from forming and casting to machining and riveting. Metal processing is a crucial part of modern manufacturing. The application of machine learning (ML) is driving a significant change in the sector, which has historically depended on empirical knowledge and trial-and-error techniques. Increased production, improved product quality, and resource optimization are expected outcomes of this action. This study aims to explore the …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 40–51 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Molecular Docking, QSAR Modeling, and ADMET Evaluation of Novel Pyrazolo-Pyrimidine Derivatives as Potential CDK-2 Inhibitors for Cancer Therapy
Abstract: Cyclin-dependent kinase-2 (CDK-2) is an essential regulator in cell cycle progression and is an important therapeutic target in cancer drug development. In the present study, an integrated computational approach involving molecular docking studies, QSAR modeling, ADMET prediction, and artificial intelligence-based analysis was used to identify pyrazolo-pyrimidine derivatives as potential CDK-2 inhibitors. Based on the molecular docking results, it was found that selected compounds exhibited high binding affinity towards the ATP …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Design, Synthesis, and in vitro Evaluation of Novel Benz/Imidazole-2-acetonitrile Derivatives as Antibacterial and Antifungal Agents
Abstract: Benzimidazole is a pharmaceutically important compound. In this research, we were able to prepare several heterocyclic derivatives from it by first preparing a new azo derivative ZH through a reaction of 3-aminoacetophenone with benzimidazole-2-acetonitrile. This azo derivative was then introduced via a condensation reaction with aromatic amine derivatives, resulting in the preparation of two Schiff base derivatives Z1 and Z2. From these bases, six and seven membered heterocyclic derivatives were …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 53–87 Read article
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A Novel Approach to Ceiling Fan-Based System for Preventing Suicide by Hanging
Abstract: Suicide by hanging has become a significant public health issue in India. According to reports from the National Crime Records Bureau (NCRB), a considerable number of hanging cases are reported annually, with the majority being suicidal in nature. Homicidal cases disguised as hanging are extremely rare. Accurate differentiation between suicidal and homicidal hanging requires thorough examination of the crime scene in an undisturbed condition, followed by a detailed autopsy investigation. …
Published in Recent Trends in Sensor Research & Technology · Vol. 13, Issue 2, 2026 Read article
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Child Friendly Innovation: A New Era in Pediatrics Drug Delivery Systems
Abstract: Pediatric formulations are becoming more and more popular as a result of advancements in pharmaceutical delivery technology. For young patients, there isn't a safe and effective drug delivery system in place. Since children's pharmacokinetics and pathophysiologic profiles differ from those of adults, it is imperative to design and develop an innovative and appropriate delivery system to provide accurate and dependable medicine administration to pediatric patients. Discussions will be held under …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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A Comprehensive Review on COVID-19 Evolution and Development
Abstract: The emerging pandemic causing flu-like symptoms in patients is caused by the novel Coronavirus that was previously called 2019-nCoV. The mutated gene of SARS-CoV was transformed to SARS-CoV-2 in animals and further transmitted to humans in the month of December 2019 in Wuhan city of China. Eventually, the novel coronavirus spread all around the globe as a highly contagious disease. COVID-19 (the illness caused by coronavirus) has affected 213 countries …
Published in Research and Reviews : A Journal of Life Sciences Read article
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Rethinking Type-1 Diabetes Treatment: Emerging Medicines Based on AAT Therapy and C-peptide Preservation Therapy
Abstract: The increasing number of cases, especially in the younger age group, along with the lack of accessible clinical solutions, make Type-1 Diabetes (T1D) a growing global health concern. While gene therapy and transplantation approaches are promising avenues, their excessively high costs and logistical difficulties make them inaccessible to the majority and can impose a financial burden on those suffering from it, adding to the challenges already faced by these advanced …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 19–29 Read article
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Assessment of Sustainable Composite for UAV structural Application
Abstract: Now-a-days aligned with global mission the growth of Unmanned aerial vehicle (UAV) application is enormous in the field of agriculture, defence, surveying etc., This research work investigates the improvement in strength of polymer matrix composite material of adding epoxy polymer resin with novel bio fibers such as Tamarindus and Morinda. The composite material was fabricated by using hand-layup method later its mechanical properties are analysed by numerical method as well …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 359–377 Read article
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Formulation and Evaluation of Aqueous Azadirachta indica Phytosome
Abstract: A phytosome is a complex created through the union of a natural compound, typically a plant extract, with a phospholipid. Phospholipids play a crucial role in cell membranes, possessing a structure comprising a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tails. This distinctive structure enables phospholipids to construct lipid bilayers, fundamental elements of cell membranes. Phytosome increases the bioavailability, and absorption of active chemical constituents in the extract with the help …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 17–30 Read article
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Coming of Age in Nature: An Ecocritical Reading of Ruskin Bond’s The Room on the Roof
Abstract: This research paper explores the human-nature relationship in Ruskin Bond's classic novel, "The Room on the Roof," through the lens of ecocriticism. Ecocriticism, a critical theory examining literature's portrayal of the environment, provides a valuable framework for analyzing the novel's themes of escape, self-discovery, and the impact of human actions on the natural world. The paper analyzes the novel, demonstrating how Bond utilizes ecocriticism to depict the transformative power of …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 1, 2024 · pp. 13–17 Read article
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Antimicrobial Peptides and Bacteriophages as Next-Generation Alternatives to Conventional Antibiotics
Abstract: The growing threat of antibiotic-resistant bacteria has underscored the urgent need for innovative alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) and bacteriophages are gaining recognition as next-generation therapeutics due to their distinct mechanisms of action and ability to target resistant pathogens effectively. AMPs, which can be natural or synthetic, disrupt microbial membranes and offer broad-spectrum antimicrobial activity with a reduced likelihood of resistance development. Bacteriophages, as bacteria-specific viruses, provide precise …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 9–27 Read article
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Hydro-alcoholic Extract of Herbal Formulation and Evaluation of Papaya leaf And Orange Peel for treatment of Dengue Fever
Abstract: The fastest-spreading viral disease in the world is dengue contamination, which is spread by mosquitoes. Carica papaya leaf juice aids in raising the platelet count, and it occurs primarily in tropical and subtropical countries. The primary goal of this study is to inform medical experts about the use of Carica papaya leaf extract formulations (SYRUP) to treat dengue fever, a potentially fatal illness. Approach: To cure this illness, a water …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 23–33 Read article
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Emerging Therapies for Diabetes Mellitus: Efficacy and Safety of USFDA-Approved Drugs and Late-Stage Clinical Trials
Abstract: This review provides a comprehensive analysis of drugs approved by the U.S. Food and Drug Administration (USFDA) for managing diabetes mellitus (DM) from 2013 to 2022, including emerging treatments from phase 3 clinical trials during this period. Over the past decade, the treatment landscape for diabetes has evolved significantly, with new therapies not only improving blood sugar control but also targeting broader health outcomes like heart and kidney health. In …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 11–23 Read article
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Current Updates On Employability Of Artificial Intelligence In Healthcare Science & Research
Abstract: Over the centuries, tools have been developed to increase refinement to manipulate different tools in many ways to use human digital computers. It can perform the same types of numerical and symbolic operations that can be done by ordinary people, but faster and more reliable. Artificial intelligence algorithms applied to computer applications and software. Include knowledge-based systems. AI is the science that mimics the mental skills of humans in computers. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 72–77 Read article
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An Analysis of Stoic Characters from the Lies I Tell by Julie Clark
Abstract: The research delves into the analysis of stoic characters from The Lies I Tell in various perspectives. The argument rests on those character's specific characteristics of being a stoic person and following the philosophies of the stoic human. Using a literary-philosophical approach, the analysis explores how both protagonists demonstrate the stoic ideal in distinct ways. Meg Williams, in her calculated acts of retribution, exhibits controlled reasoning and a deep, though …
Published in Emerging Trends in Languages · Vol. 3, Issue 1, 2026 · pp. 8–12 Read article