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1949 articles for “DR” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Unveiling Nature’s Potential: In Silico Exploration and Identification of Herbal Remedies for Major Depressive Disorder Through Molecular Interaction Studies
Abstract: Major depressive disorder (MDD), a globally discussed mental health condition, has drawn significant attention because of its unique and intricate nature. This is marked by the enduring presence of negative emotions stemming from a lack of interest, diminished self-esteem, and excessive rumination. Despite the widespread availability of various antidepressant medications, their effectiveness is hindered by low response rates, prolonged treatment durations, and the prevalence of side effects, such as headaches, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 54–62 Read article
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Development of Sodium Alginate Beads of Telmisartan Using Emulsion Gelation Method: Formulation and In-Vitro Characterization
Abstract: Introduction: The antihypertensive medication Telmisartan (TEL) is a member of BCS class II, which is distinguished by limited oral rate and extent and water solubility. By localizing the medication release in the stomach, gastro-retentive floating bead devices may be able to address the issues related to partial absorption and the low solubility of TEL. The preparation of TEL floating alginate beads was the aim of this investigation. The current work …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 13–21 Read article
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Enhancing Road Safety: A System for Vehicular Accident Detection, Prevention, and Rescue Alerts
Abstract: The Vehicular Accident Detection, Prevention, and Rescue Alert System is a comprehensive solution aimed at bolstering road safety by integrating multiple advanced technologies. It merges drowsiness detection, alcohol level monitoring, and instant emergency alerts to mitigate accidents and expedite rescue efforts. Modern computer vision and machine learning techniques are used by the Drowsiness Detection Alarm to track driver conduct and spot drowsiness indicators. Upon detecting drowsiness, an immediate alarm is …
Published in International Journal of Solid State Innovations & Research · Vol. 2, Issue 2, 2024 · pp. 7–11 Read article
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Torsade de Pointes: A Comprehensive Review of Pathophysiology and Therapeutic Approach
Abstract: Torsade de pointes (TdP) is a rare form of polymorphic ventricular tachycardia, marked by fluctuating QRS complex amplitudes that twist around the isoelectric line on an electrocardiogram (ECG). It is commonly linked to prolonged QT intervals, which can be either acquired or congenital. While TdP often resolves spontaneously, it may lead to fatal ventricular fibrillation if untreated. Medications, electrolyte imbalances, and genetic conditions like Jervell and Lange-Nielsen syndrome contribute to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 1, 2025 · pp. 36–41 Read article
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Screening of Newer Phytoconstituents on Novel Enzymes for their Biological Activity
Abstract: Background: Hyperlipidemia and gout are prevalent metabolic disorders significantly impacting global health. The xanthine oxidase and HMG-CoA reductase pathways play pivotal roles in the pathophysiology of these conditions. This study explores the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors for these enzymatic targets, offering insights into innovative therapeutic strategies. Aim: To evaluate the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors of xanthine oxidase and HMG-CoA reductase …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 81–86 Read article
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A Comprehensive Review of CNN-Based Framework for Multi-Sign Detection of Diabetic Retinopathy in Fundus Images Using Public Datasets
Abstract: Diabetic retinopathy (DR) is one of the main causes of vision impairment. Blindness prevention and effective treatment depend on early detection. A thorough deep learning-based framework for the automatic segmentation and simultaneous detection of exudates, hemorrhages, and microaneurysms – three important DR indicators – from retinal fundus images is presented in this work. These three pathological signs’ corresponding annotated image patches, along with background (no-sign) areas, were used to train …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article
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Harnessing Polymer Chemistry for Pharmaceutical Technology
Abstract: Polymer chemistry has emerged as a cornerstone of modern pharmaceutical technology, offering unprecedented control over drug formulation, delivery, and therapeutic performance. This review highlights the pivotal role of polymers—both synthetic and natural—in revolutionizing drug delivery systems across various routes, including oral, parenteral, transdermal, ocular, nasal, and pulmonary administration. Special emphasis is placed on the structural and functional versatility of polymers, which allows for tailored drug release profiles, enhanced bioavailability, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1–6 Read article
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Revolutionizing Artificial Organs: Next-Generation Membrane Technologies for Precision Medicine and Global Health
Abstract: Membrane technology has emerged as a cornerstone in the advancement of artificial organ systems, offering critical functionalities in selective molecular filtration, tissue scaffolding, and controlled therapeutic delivery. Recent innovations have propelled the field beyond traditional polymeric membranes to include nanostructured, biomimetic, and stimuli-responsive materials, significantly enhancing biocompatibility, selectivity, and durability. The integration of smart technologies, such as AI-driven membrane design, bioelectronic sensors, and personalized fabrication via 3D printing, is ushering …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 29–39 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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Structural Integrity Analysis of Reinforced Concrete Frames Under Progressive Collapse Scenarios
Abstract: This study examines how a tall reinforced concrete (RC) frame may gradually collapse under several column removal situations, such as edge, end, center, zigzag, and two-column failures. The study assesses the structural reaction based on displacement, inter-story drift, and Demand–Capacity Ratio (DCR) using nonlinear static pushover analysis carried out in ETABS. According to the analysis, the frame's stability is seriously jeopardized when two nearby columns and end columns are removed, …
Published in Journal of Geotechnical Engineering · Vol. 12, Issue 3, 2025 · pp. 1–15 Read article
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Hydrodynamic Assessment of a Proposed FSRU Development in the Visakhapatnam Outer Harbour
Abstract: This study presents a detailed hydrodynamic assessment of a proposed Floating Storage andRegasification Unit (FSRU) in the Visakhapatnam Outer Harbour. A depth-integrated, two- dimensional hydrodynamic model was developed using MIKE-21 Flexible Mesh (FM) to quantify theinfluence of the terminal layout, dredged pocket configuration, and vessel presence on tidal circulation, freshet-driven flows, and extreme-event conditions. Baseline simulations were performed using existing bathymetry and operational geometries, followed by proposed configurations that included …
Published in Journal of Offshore Structure and Technology · Vol. 13, Issue 1, 2026 · pp. 39–49 Read article
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Trends, Challenges, and the Future of Unmanned Aerial Systems
Abstract: The rapid evolution of unmanned aerial vehicles (UAVs), commonly referred to as drones, has transformed numerous domains — from military surveillance and logistics to precision agriculture and atmospheric research. This paper examines the current state of drone technology, industry trends, regulatory frameworks, socio-economic impacts, ethical considerations, and future research directions. With contributions from multidisciplinary studies, this review emphasizes emerging technologies, performance metrics, risk factors, and opportunities for innovation. In recent …
Published in International Journal on Drones · Vol. 2, Issue 1, 2026 · pp. 27–33 Read article
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Impact of Vaccine Awareness Campaigns on Pharmacovigilance Reporting and Public Safety Monitoring
Abstract: Vaccination programs have significantly contributed to the reduction of infectious diseases worldwide; however, their success is closely tied to public confidence and robust safety monitoring systems. Pharmacovigilance plays a critical role in identifying, assessing, and preventing adverse events following immunization (AEFI). In recent years, vaccine awareness campaigns have emerged as a pivotal strategy to improve public knowledge, reduce vaccine hesitancy, and enhance reporting of adverse drug reactions (ADRs). This review …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Integrative Therapeutics for Antimicrobial Resistance and Autoimmune Disease: Evidence and Pathways
Abstract: Background: Antimicrobial resistance (AMR) is accelerating globally, while autoimmune diseases and adverse drug reactions (ADRs) continue to rise. Ayurveda offers immunomodulatory, antimicrobial, and detoxification‑oriented interventions that may complement biomedical strategies. Objective: To propose a hypothesis‑driven integrative model combining Ayurvedic phytotherapy, panchakarma detoxification, and personalized dosha‑based care with evidence‑based medical management to mitigate AMR emergence, modulate autoimmunity, and reduce ADR incidence. Methods: A synthesis of mechanistic literature on Ayurvedic herbs with …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 25–30 Read article
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Real-time Water Quality Analysis Using Fuzzy Logic
Abstract: Nowadays the availability of safe drinking water is very difficult. In our project we are analysing water quality using different parameters like pH, turbidity, temperature and TDS for determining its safety level by monitoring the data from the readings. Moreover, we have a monitoring system for the data and also a webpage where all the data from these system is displayed. The sensors are connected to an Arduino Nano microcontroller …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 2, 2026 · pp. 01–11 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Numerical Study and Comparison of Passive Mixing in Helical Micromixers
Abstract: A passive mixing inside three micromixers has been studied with water as the mixing fluid. Since the mixing at the micro-level is governed by species diffusion hence it is a time-consuming process that requires an extended length of micromixer for the required amount of mixing. The present study tackles this problem by introducing two helical micromixers, a Three-dimensional helical micromixer (TDHM), and TDHM having four inlets (TDHM-FO). These micromixers need …
Published in Journal of Polymer & Composites Read article
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A Global Impact of Pharmaceutical Pollution
Abstract: Pharmaceutical products play an important role in our daily life in which consumption medicine is essential in need of curing the disease. As the requirement of the pharmaceuticals is more important in human life the production of medicine is in more demanded in global level in our day-to-day life. The most important aspects are the other side in which the pollution of the pharmaceuticals is caused due to the manufacturing, …
Published in Research and Reviews: A Journal of Toxicology Read article
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Prototype Model Development and Design Analysis of A Solar Tricycle for Physically Challenged People in India
Abstract: Society is greatly concerned about the mobility of individuals with physical disabilities. The scarcity of energy resources and the issue of pollution are currently the primary concerns. These issues can be resolved by employing alternative energy sources such as solar power. This paper presents an overview of the existing solar tricycles designed for those with disabilities. It also improves a handicapped-friendly solar-powered tricycle. The goal is to reduce handicapped people's …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 43–56 Read article