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60 articles for “Antagonistic”
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An Insight to Hyponatremia in Cirrhosis: Pathophysiology and Management Approaches
Abstract: Cirrhosis is considered by systemic and splanchnic vasodilation that principals to extreme nonosmotic excretion of vasopressin. Hyponatremia is a mutual electrolyte irregularity in progressive liver disease that outcomes from the diminished capability of the kidney to excrete solute-free water that principals to “dilutional” hyponatremia water retention uneven to the retaining of sodium. Hyponatremia is mutual in cirrhosis. It frequently happens in a progressive phase of the disease and is related …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 30–46 Read article
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Computational Identification of Protein Tyrosine Phospatase-1B (PTP-1B) Inhibitors for Checking Type II Diabetes
Abstract: Protein tyrosine phosphatases (PTPs) are a family of enzyme that comprises of about 100 proteins which catalyze dephosphorylation of phosphotyrosine residues in protein substrates. Phosphotyrosine is a central element in cell signaling, and its activity is essential for cellular homeostasis and for appropriate responses to extracellular signals. PTP-1B antagonizes insulin signaling by reducing the activation state of the insulin receptor kinase, thereby inhibiting post-receptor signaling in insulin responsive tissue. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 3, 2017 · pp. 21–25 Read article
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Determining the Antimicrobial Activity of Lactic Acid Bacillus against Candida albicans
Abstract: Candida albicans is human commensal yeast that colonizes the gastrointestinal tract in over half of healthy individuals. Candida are almost universal in low numbers on healthy adult skin and C. albicans is part of the normal flora of the mucous membranes of the respiratory, gastrointestinal and female genital tracts. The present study was carried out to determine their antimicrobial and antagonistic effect against the Candida albicans. The Lactic Acid Bacillus …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 2, 2018 · pp. 1–5 Read article
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Promising Antimicrobial Compounds from an Endophytic Fungus Penicillium daleae EF 4 Isolated from the Seaweed Enteromorpha flexuosa Linn.
Abstract: AbstractThe present aim of the study is to isolate the endophytic fungi from various seaweeds and to screen their bioactivity, to analyze the β-lactamase inactivator and to evaluate the interactions between the crude extract of Endophytic fungi Penicillium daleae EF 4 and two antibiotics (penicillin G and tetracycline), against some antibiotic resistant bacterial strains. Seaweeds collected from various places of Bay of Bengal coast was subjected to Endophytic fungal isolation. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 26–39 Read article
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Bacilli: The Keystone Biocontrol Agents Eradicating Phytopathogens
Abstract: As a result of the niches provided by plants to microbes, multitude of interactions occurred some of which are detrimental to the plants, including pathogenicity which results in diseased plants caused by harmful microbial community inhabiting a plant. Studies have shown that pesticides are applied to control the disease-causing microbes, but the adverse effects of the pesticides have necessitated the need for biocontrol agents that are eco-friendly. In this article, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 1, 2023 · pp. 22–32 Read article
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Antibacterial Action of Bacillus coagulans Against Diverse Pathogens and its Relevance as Probiotics
Abstract: Probiotics are living organisms that give benefits to the host organism by improving the intestinal microbial balance. Probiotics have various beneficial effects as it maintains a healthy gut, healthy vaginal flora and boost the immune system. There are different strains of lactic acid bacteria that are used as probiotics but Bacillus coagulans is a good bacterium that is used in the form of probiotic supplements. In the present study, B. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 2, 2023 · pp. 21–25 Read article
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Obsessive-Compulsive Disorder and Marijuana
Abstract: Obsessive-compulsive disorder (OCD) has both negative and positive attributes. Those with OCD find themselves genetically endowed with traits that will help them succeed in life--creativity, a sense of detail/symmetry, tenacious motivation, and a propensity for achievement in the arts, writing, and education. Without one major caveat though, OCD would be a strong quality for general success--the life of one with OCD may be overly complex and mentally tortuous. In this …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 6, Issue 3, 2016 · pp. 30–34 Read article
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Effects of Sub Chronic Dermal Exposure of Gasoline Blended with Varying Concentration of Benzene on Hepatic Mixed Function Oxidases in Rats
Abstract: Interaction of chemicals in a mixture, their biotransformation and adverse impact, if any, on environment and workroom atmosphere needs to be evaluated to identify the nature of potential toxic effects elicited by constituent chemical(s) in a mixture. The nature of chemical interaction(s) through which an individual chemical in a mixture undergoes metabolism and/or biotransformation in the target tissue could be helpful in evaluation of its toxic potential. Gasoline is a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 1–5 Read article
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Cognitive Impairment in Alzheimer’s Disease
Abstract: Alzheimer's disease (AD) is a condition that leads to the deterioration of brain cells and is the primary cause of dementia, characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis are the two main theories proposed to explain AD's multifaceted nature. Characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
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The Concept of E-learning
Abstract: In today's educational environment, e-learning is extremely important. It has the potential to transform the entire educational system. Traditional learning has gained a new smart way of learning and teaching, and as a result, it has become one of the most popular subjects among researchers. Elearning- related research is conducted in a variety of fields, including mass communication, education, information technology (IT), and distance education. Experts work on a variety …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 9, Issue 1, 2022 · pp. 20–26 Read article
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Biocontrol Agents for The Management of Rhizoctonia Solani in Rice
Abstract: The sheath blight caused by Rhizoctonia solani is an important disease in rice. The bacterial antagonists were tested for their potential to suppress R. solani in dual cultures. Pseudomonas fluorescens isolate 27 was effective in reducing the mycelial growth and sclerotial number of R. solani followed by Pf 2. In pot culture also, seed bacterization, root bacterization and foliar spray with Pf 27 individually controlled the rice sheath blight disease …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 1, Issue 1, 2011 · pp. 41–44 Read article
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Effect of Complexation of Copper with a Preferred Amino acid of Saccharomyces cerevisiae NCIM 3558 on its Metabolism
Abstract: The present work studies the effect on the growth of Saccharomyces cerevisiae NCIM 3558when copper sulphate pentahydrate is complexed with a preferred amino acid of S.cerevisiaeNCIM. The study showed the fact that not only the amino acid or ligand but also the metal ioninvolved is an important factor for the biological effects of ligand–metal complexes effects onyeast metabolism per se. Studies are elaborated extensively.Keywords: Saccharomyces cerevisiae, glutamine copper, antagonist, glucose …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 7, Issue 2, 2017 · pp. 7–11 Read article
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Research Insight: Toxicology
Abstract: Toxicology is an apprehensive study of the antagonistic effects of chemicals on living entities. It also studies the detrimental special effects of chemical, biological and physical proxies in biological systems that inaugurate the extent of loss in living organisms. The association between dose and its effects on the wide-open entity is of prodigious implication in toxicology. The factors that sway chemical toxicity include dosage, the route of exposure, the species, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 23–26 Read article
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A SUBSTANTIAL PROBLEM OF WATER POLLUTION: REASON & SOLUTION
Abstract: Human exercises including industrialization and farming practices contributed massively in no little measure to the corruption and contamination of the earth which antagonistically affects the water bodies (waterways and sea) that is a need forever. This paper attempts to talk about essentially what water contamination is and similarly to address the source, impact control and water contamination the board overall. A few proposals, for example, presentation of ecological training were …
Published in Journal of Water Pollution & Purification Research · Vol. 5, Issue 3, 2018 · pp. 10–14 Read article
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Molecular Interaction and Simulation Studies of Inhibitors for Endothelin-1 Receptors
Abstract: High altitude cerebral edema (HACE) is a life threatening severe form of acute mountain sickness (AMS) which causes headache, unbalanced gait, behavioral changes, and altered mental status. It also carries features like hallucinations or coma, as well as a variety of neurological deficits. Prevention of edema fluid formation with minimal side effects remains to be discovered. Endothelin-1 receptors were found to be involved in the pathogenesis of HACE. Due to …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 3, 2015 · pp. 15–26 Read article
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In Silico Tau Protein Kinase I Inhibitory Activity of Some Commercially Available Flavonoids
Abstract: Molecular docking is a frequently used tool in computer-aided structure-based rational drug design. Flavonoids are a group of natural products which exhibits various biological and pharmacological activities. The primary objective of this study was to investigate the tau protein kinase I inhibitory activity of flavonoids using in silico docking studies. Memantine, a known neuro-receptor antagonist is currently used in the treatment of Alzheimer’s disease (AD). In silico docking studies were …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 6–12 Read article
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Spectrophotometric Method for the Estimation of Levosulpiride in Bulk Drug and Formulations
Abstract: Levosulpiride having D2-dopamine receptor antagonistic activity gives ant depressive and antiulcer effect. There are three new simple accurate, rapid, economical and precise procedures for spectrophotometric estimation of Levosulpiride in bulk and pharmaceutical formulation. Levosulpiride was estimated at 291.5 nm in 0.1 N NaOH, 290 nm in 0.1 N HCl and 292.5 nm in 6.8 phosphate buffer. Linearity range was found to be 10–50 µg/mL in all the three methods. The …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 19–23 Read article
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Risperidone: A Silver Lining In Mental Disorders
Abstract: Risperidone (RYKINDO®) is second generation benzisothiazole which elevates linkage to serotonin type 2 (5HT2A) and dopamine type 2(D2) receptor developed by Luye Pharma Group used in short term palliative treatment of aggression or psychopathic disorders. Both 5HT2 antagonism with D2 receptor, it selectively bind to 5HT2A antagonist and shows neuroleptic effect by Risperidone. It is also available in the form of oral solution and disintegrating tablet etc. It is long …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 3, 2023 · pp. 11–21 Read article
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An Overview of Anticoagulants in Treatment of Thrombosis and Related Disorders: A review
Abstract: With the increasing ageing of population, clinicians are encountering patients with atrial fibrillation and venous thromboembolism who require anticoagulant therapy to prevent stroke and systemic embolism. Due to its high prevalence and unfavorable results, the treatment of thromboembolic disease has become a clinically important area. Traditional anticoagulants such as heparin, low molecular weight heparin, and warfarin have been used to prevent and treat venous and arterial thrombosis. However, bleeding problems, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 2, 2023 · pp. 1–8 Read article
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A Brief Review on Inflammatory Mediators and Drug Therapy for Rheumatoid Arthritis
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease which is characterized by inflammation of the joints and destruction of cartilage and bone. The disease pathology is complex which involves the infiltration and activation of various populations of immune cells along with the release of destructive inflammatory mediators into the synovium of affected joints. Several inflammatory mediators are involved in just like IL-1, IL-6, IL-8, IL-17, IL-18 and tumour necrosis factor-alfa. Treatment …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 1–4 Read article