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Research and Reviews: A Journal of Pharmacology

An Overview of Anticoagulants in Treatment of Thrombosis and Related Disorders: A review

  1. Walli Mohammed
  2. Dr. Hemant Sharma

Abstract

With the increasing ageing of population, clinicians are encountering patients with atrial fibrillation and venous thromboembolism who require anticoagulant therapy to prevent stroke and systemic embolism. Due to its high prevalence and unfavorable results, the treatment of thromboembolic disease has become a clinically important area. Traditional anticoagulants such as heparin, low molecular weight heparin, and warfarin have been used to prevent and treat venous and arterial thrombosis. However, bleeding problems, parenteral routes of administration, or the need for frequent monitoring due to various reactions limit their use. This article outlines coagulation along with existing treatments available for anticoagulant therapy, starting with naming schemes, strengths, weaknesses, precautions, and contraindications compared to vitamin K, and the new oral anticoagulant (NOAC). Get the latest information on the benefits of and recent advances. Antagonists (VKA) based on various recent studies and clinical trials.

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