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1721 articles for “association”
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The Relationship Between HbA1c and Inflammatory Markers in Acute Ischemic Stroke with and without Diabetes Mellitus
Abstract: Background: Diabetes mellitus (DM) is a prominent risk factor for acute ischemic stroke (AIS), contributing significantly to morbidity and mortality worldwide. Although inflammatory markers like neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP) are recognized as playing a role in the development of acute ischemic stroke (AIS), their association with diabetes mellitus (DM) in individuals affected by AIS remains uncertain. This study seeks to investigate the differences in …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 57–66 Read article
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Enhancing Compressive Strength and Durability through Optimization of Concrete Mixtures
Abstract: This research investigates how varying cement-aggregate ratio, water-cement ratio, and slump height affect the compressive strength of concrete mixtures. Through an analysis of 36 samples, each representing different combinations of these parameters, significant insights are gained into the optimization of concrete mix designs for construction applications. The study reveals that higher water-cement ratios tend to decrease compressive strength due to increased porosity in cured concrete. Conversely, higher cement-aggregate ratios generally …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 1, 2024 · pp. 1–12 Read article
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Revolutionizing Gastro-retentive Drug Delivery: Exploring Innovative Formulation Strategies and Mechanisms in Floating in Situ Gel Raft Forming System
Abstract: An in-depth exploration of the transformative shift underway in gastro-retentive drug delivery, spotlighting the utilization of Floating Drug Delivery Systems (FDDS) and specifically honing in on the innovative formulation strategies and mechanisms inherent in Floating In Situ Gel Raft Forming Systems. FDDS present a promising avenue for revolutionizing drug delivery efficacy by capitalizing on buoyancy to float atop the gastric fluid surface, thereby extending gastric residence time and improving drug …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 9–21 Read article
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
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Facial Biometrics Driven Attendance Automation Solution Using LBPH Algorithm
Abstract: In today's educational landscape, managing attendance remains a central administrative task, often conducted manually on paper, consuming valuable time for educators. This project proposes a solution utilizing facial recognition technology to streamline the attendance process, thereby saving time and maintaining accurate student records. The objective is to develop an automated attendance system that is minimally intrusive, cost-effective, and highly efficient, leveraging computer vision techniques and algorithms like local binary patterns …
Published in Journal of Open Source Developments · Vol. 11, Issue 1, 2024 · pp. 27–35 Read article
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Protective Effects Of Curcumin Against Osteoporosis And Its Molecular Mechanism
Abstract: One of the most prevalent metabolic disorders is osteoporosis (OP), which primarily affects postmenopausal women and the elderly. It is often associated with gradual loss of bone density, ongoing destruction of bone microstructure, and increased risk of osteoporosis. Pharmacotherapy is the primary approach for treating and preventing osteoporosis. However, persistent medication therapy invariably results in drug responses and particular adverse effects. Therefore, scientists continue to search for new monomeric compounds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 16–23 Read article
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Cementing Sustainability: Utilizing Waste Foundry Sand to Enhance Concrete Performance and Reduce Environmental Impact
Abstract: The incorporation of waste foundry sand into concrete production represents an environmentally conscious and cost-effective approach. This method involves substituting discarded foundry sand for a portion of traditional fine aggregates in concrete mixtures. The primary objective is to address environmental concerns associated with waste disposal while simultaneously achieving cost efficiency in construction materials. By integrating waste foundry sand into concrete, this practice promotes sustainability by reducing landfill waste and conserving …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 1, 2024 · pp. 13–21 Read article
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Screening and Isolation of Bacterial Isolates for Polyhydroxyalkanoates Production from Oil-Contaminated sites
Abstract: Synthetic polymers are generally manufactured from petroleum and chemical-based sources. These polymers are employed in day-to-day life basic needs which leads to the production of huge number of synthetic polymers that accumulate in nature for thousands of years. There are limitations associated with synthetic polymers apart from their non-biodegradability, non-compatibility their mechanical and physical properties that cannot be easily altered narrows their few applications. PHAs (polyhydroxyalkanoates) are biopolymers that can …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 1–6 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Comparative Study to Assess the Knowledge of Higher Secondary School Students Regarding Career Counselling in Selected Rural and Urban Schools of Kashmir
Abstract: Background: Career counseling assists individuals in choosing appropriate educational and occupational choices and making career options based on future employment demands and requirements. Career counseling comprises a wide variety of professional activities that assist people in overcoming career-related obstacles. Aim: The primary objective of the study was to evaluate the understanding of career counseling among students in chosen rural and urban high schools in Kashmir. Method: This study employed a …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 11–18 Read article
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Speech Therapy in the Digital Age: Telepractice and Remote Interventions
Abstract: In the digital age, advancements in technology have revolutionized various aspects of healthcare, including speech therapy. This study explores the emergence and evolution of telepractice and remote interventions in speech therapy. Telepractice, interchangeably labelled as teletherapy or telehealth, denotes providing speech therapy services remotely using telecommunication technology. Its incorporation into speech therapy has broadened service accessibility, notably benefiting underserved or remote locales. Moreover, it has ensured uninterrupted care delivery during …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 42–46 Read article
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Long non-coded RNA, cancer, immune cells, tumor micro-environment, immuno-oncology, immune escape, cancer-immune cycle, lncRNA signature
Abstract: Developing data from current research reveals fresh insights into the roles played by long non-coding RNAs (lncRNAs) in immuno-oncology. Long non-coding RNAs (lncRNAs) not only influence the aggressiveness of cancer cells but also play a crucial role in controlling different immune cells and stromal cells, which in turn changes the tumor micro-environment and impacts anti-tumor immunity. The significance of predictive indicators derived from long non-coding RNAs (lncRNAs) is underscored by …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 7–26 Read article
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Role Strain Among Male Nursing Students in Selected Nursing Colleges in Mangalore
Abstract: Background: The role is the behavior that is expected out of a person in a particular status. Social standards influence the advantages and responsibility of a status, and roles are performed in accordance with social standards. Role strain is the stress that occurs if they are not able to meet the expected role in their life and are facing inequalities in their profession. Objective: To assess the role strain among …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
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Importance of inflammatory marker ratio and lipid profile ratio in Acute Ischemic Stroke
Abstract: Background: Acute Ischemic Stroke is a chronic inflammatory disease that is projected to be one of the leading causes of mortality affecting millions of people globally. It is essential to study the Platelet lymphocyte ratio (PLR), Neutrophil lymphocyte ratio (NLR) ratios and C reactive protein (CRP) in impacting the inflammatory status during stroke. It is also important that altered lipid metabolism could influence the inflammatory conditions associated with AIS. Hence …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 19–31 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Overview of Recent Advancement of Nano Stent in Pharmaceutical Application
Abstract: Interventional cardiology has witnessed remarkable progress with the evolution of nanotechnology, leading to the development of nanostents. Nanostents, characterized by their nanoscale features and innovative materials, have emerged as a cutting-edge solution for addressing the limitations associated with traditional stent technologies. This thorough analysis examines the most recent developments in the design, manufacture, and use of nanostents, emphasizing how they may completely transform vascular interventions. The first section of the …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 22–43 Read article
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Psychosomatic and Psychodynamic Nature of Migraine and its Emerging Homeopathic Remedies.
Abstract: A unilateral headache with or without aura with throbbing or pulsating pain, associated with nausea or vomiting, and light and sound sensitivity is Migraine. The most common type of migraine is without aura (75% of cases). The triggers for Migraine are Sensory: Visual, Auditory, and Olfactory; Somatosensory-Touch; Physiological: Hunger, Physical exertion, and Change in sleep pattern, Linked to the Menstrual cycle; Dietary aspects: Chocolate, Alcoholic Beverages, Cheese, Processed Meat, Food …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2024 · pp. 26–31 Read article
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Enhancing Security and Privacy in Smart Factory: A Blockchain Based Solution
Abstract: The manufacturing industry is currently experiencing a transformative shift due to the rise of smart factories, propelled by interconnected devices and automated systems. However, this integration of diverse technologies within smart factories introduces significant concerns regarding security and privacy. This research paper thoroughly investigates the vulnerabilities and threats prevalent in smart factory ecosystems, shedding light on the potential risks associated with centralized data storage and communication channels. The study emphasizes …
Published in International Journal of Wireless Security and Networks · Vol. 2, Issue 1, 2024 · pp. 13–20 Read article
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Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19
Abstract: The COVID-19 pandemic has brought attention to the need for rapid, accurate, and scalable diagnostic techniques. Metagenomics, a powerful technique that enables the comprehensive analysis of genetic material from complex microbial communities, has emerged as a promising diagnostic approach for COVID-19. This article elucidates the principles of metagenomic sequencing, highlighting its ability to detect viral RNA directly from clinical samples without prior knowledge of the pathogen. Furthermore, we discuss the …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article