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61 articles for “Antimicrobial Agents”
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Formulation, Evaluation, and Stability Studies of a Topical Clotrimazole and Zinc Oxide Suspension with Enhanced Skin Protective Properties
Abstract: Background: Clotrimazole is a well-known antifungal agent frequently used in the treatment of various superficial fungal infections, while Zinc Oxide is a widely accepted skin protectant with soothing, astringent, and antimicrobial properties. Combining these agents in a topical suspension offers a dual therapeutic approach, enhancing both antifungal efficacy and skin protection. Objective: The objective of this study was to formulate, evaluate, and conduct stability studies on topical suspensions containing Clotrimazole …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 22–31 Read article
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Integrative Therapeutics for Antimicrobial Resistance and Autoimmune Disease: Evidence and Pathways
Abstract: Background: Antimicrobial resistance (AMR) is accelerating globally, while autoimmune diseases and adverse drug reactions (ADRs) continue to rise. Ayurveda offers immunomodulatory, antimicrobial, and detoxification‑oriented interventions that may complement biomedical strategies. Objective: To propose a hypothesis‑driven integrative model combining Ayurvedic phytotherapy, panchakarma detoxification, and personalized dosha‑based care with evidence‑based medical management to mitigate AMR emergence, modulate autoimmunity, and reduce ADR incidence. Methods: A synthesis of mechanistic literature on Ayurvedic herbs with …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 25–30 Read article
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Exploring the Potential of Allium sativum Phytocompounds as B-Cell Leukemia 2 Inhibitors in Acute Lymphoblastic Leukemia: Molecular Docking Study
Abstract: Objective: Acute lymphoblastic leukemia (ALL) is a lymphoid progenitor cell malignancy that could be treated with plant-based drugs, thus alleviating the off-target effects caused by conventional chemotherapy. Since ancient days, Allium sativum has been an integral part of traditional medicine and an excellent antimicrobial, antioxidant, and antiproliferative agent. Hence, this study aims to assess the anti-leukemic potential of A. sativum phytoconstituents as the B-cell leukemia 2 protein (Bcl-2) natural inhibitor …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 53–80 Read article
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Role of Therapeutic Index for Local Infections Score in Wound Assessment
Abstract: Local wound infections pose a significant challenge, often detected later, leading to complications like systemic infections. Global nomenclature lacks uniformity, resulting in varied treatments for similar diagnoses. Early intervention is crucial, advocating for local antimicrobial therapy with diverse active agents to avoid systemic antibiotics and mitigate bacterial resistance. The Therapeutic Index for Local Infections (TILI) score, innovated by the German society Initiative Chronis Che Wenden (ICW), emerges as a pivotal …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 44–48 Read article
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Concurrent Acute Fatty LIVER of Pregnancy, Acute Hepatitis, And Viral Meningitis in An Advanced Maternal Age Pregnancy a Rare Triple Presentation
Abstract: Background: Acute fatty liver of pregnancy (AFLP) is a sometimes lethal, but very seldom, chronic hepatic disease during late pregnancy. The presence of AFLP with other severe diseases raises the level of diagnostic and therapeutic complexity to a higher level. Case Presentation: We present the case of a 45 years old multigravita and 26 weeks of gestation with a distinct triad of AFLP, acute viral hepatitis (cytomegalovirus [CMV] and herpes …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 7–11 Read article
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Comprehensive Review of Kojic Acid and Its Derivatives: Biological Activities, Safety, and Therapeutic Potential in Depigmentation
Abstract: There are several uses for kojic acid in human medicine, particularly in depigmentation. Additionally, derivatives of it are suggested to enhance efficacy, avoid side effects, and stop chemical degradation. With an eye toward human use and an attempt to clarify the action mechanisms, the goal of this study was to review the most recent scientific literature regarding the biological activities and safety information of kojic acid or its derivatives. During …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 45–53 Read article
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Properties and antimicrobial activity of bacterial nanocellulose composite incorporated with silver nanoparticles based on green synthesis
Abstract: Green silver nanoparticles (AgNPs) synthesized using medical plant extracts as capping and reducing agents demonstrate broad applicability in addressing the threat posed by infections. In this study, we present a sustainable, low-toxicity, and cost-effective bacterial nanocellulose composite with silver nanoparticles based on green synthesis that uses Origanum vulgare as a reducing agent due to numerous biological components. The formation of AgNPs in composite and morphological properties was analyzed using scanning …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 323–328 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Antimicrobial Coatings in Biomedical Applications
Abstract: Since they make medical equipment more biocompatible and practical, biomedical polymers are quite crucial for the advancement of medical technologies. One of the most exciting applications for biomedical polymers is their possible use as protective drug coatings for devices. These coatings aim to limit bacterial binding and biofilm growth, two key causes of illnesses acquired after implantation. Scientists are searching for fresh approaches to combat microorganisms as the issue of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 392–405 Read article
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Polymer-Based Chemistry of Carbohydrate-Derived Fulvic Acid and Its Comparative Effect with Chelating Agents on Root Dentin Microhardness
Abstract: The interaction between the polymer science and the endodontic biomaterials field has increased recently while considering the search for chelating agents. CHD-FA (Carbohydrate-Derived Fulvic Acid), a naturally occurring low-molecular-weight polymeric organic acid, has potential chelating and antimicrobial and antioxidant activities. This investigation examines the polymeric chemistry of CHD-FA and compares the effect of CHD-FA with other chelating agents, ethylenediaminetetraacetic acid (EDTA), and citric acid, on root dentin microhardness. A total …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1051–1061 Read article
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Evaluation of Bio-Based Polymer Composites Containing Guava Leaf Extract for Antimicrobial Functionality
Abstract: This study explores the formulation of an herbal soap using guava leaf extract as a primary ingredient. Guava leaves are a rich source of biopolymers like pectin and cellulose, which may contribute to the binding properties in the soap. The antimicrobial activity of the soap was evaluated against common skin pathogens (Staphylococcus aureus, Trichoderma spp., Aspergillus spp.). The formulated soap exhibited inhibitory effects against all tested pathogens. The weight, foaming …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 875–880 Read article
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Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article
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Patient Profile and Antimicrobial Susceptibility Testingin Clinical Isolates of Staphylococcus aureus
Abstract: INTRODUCTION: Staphylococcus aureus is a gram-positive bacterium capable of causing various infections, ranging from minor skin infections to serious bloodstream infections. The rise of methicillin-resistant S. aureus (MRSA) strains has made treating these infections more challenging, as MRSA is frequently resistant to several types of antibiotics.. OBJECTIVE: The aim of this study was to investigate the patient profile and antimicrobial susceptibility patterns of clinical isolates of S. aureus in a …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 31–38 Read article
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Biosynthesis of Zinc Oxide Nanoparticles and Their Revolutionary Impacts on Agroindustry: Review
Abstract: Nanotechnology is a new approach of science which provides alternative tool in many fields including agriculture. This comprehensive review focuses on the biosynthesis and characterization of zinc oxide nanoparticles (ZnO NPs), highlighting their vast potential in agroindustry applications. Unlike traditional physical and chemical methods, which are often costly, time-consuming, and involve hazardous materials, this review explores the promising biological synthesis routes, offering a more sustainable and eco-friendly alternative for producing …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 2, 2024 · pp. 33–50 Read article
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Microorganisms used in aquaculture
Abstract: Microorganisms play a vital role in the health and sustainability of aquaculture systems, contributing to water quality management, disease control, and the overall productivity of aquatic farms. Beneficial microorganisms, including bacteria, fungi, algae, and probiotics, are increasingly recognized for their positive impact on aquaculture operations. These microorganisms can enhance nutrient cycling, promote the breakdown of organic waste, and reduce the need for harmful chemicals, thus improving the environmental footprint of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article
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A Review on Loading Methodologies of Active Aromatic Substance into Biopolymers
Abstract: Biopolymer-based films are increasingly being studied as sustainable alternatives to conventional packaging materials due to their biodegradability, renewability, and potential for functionalization. There are several natural polymers in the category of biopolymers such as soy protein, zein, cellulose, chitosan, and several other biodegradable synthetic polymers such as polylactic acid and polycaprolactone. However, these often show limitations in barrier properties, mechanical strength, and resistance to microbial contamination. To overcome these drawbacks, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 9–13 Read article
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Antidiabetic Potential of Bryophyllum pinnatum: A Study on its Pharmacological Effects and Synergistic Action with Glibenclamide
Abstract: Diabetes is a long-term metabolic disorder that profoundly impacts an individual’s overall health, social interactions, and quality of life. While significant progress has been made in diabetes management with the use of medications such as insulin and oral hypoglycemic agents, the limitations of these existing treatments highlight the need for new therapeutic alternatives. Moreover, the high cost of current diabetes medications makes them inaccessible to many, particularly in rural areas …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 18–30 Read article
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Recent Advances in Transition Metal Complexes with Phenyl Acetic Acid and Pseudo Halogen: Synthesis, Characterization and Applications
Abstract: A well established strategy is to introduce a biologically relevant organic molecule in coordination sphere of transition metal complexes to increase the selectivity and biocompatibility. Phenylacetic acid (PAA), an organic molecule with a phenyl functional group and a carboxylic acid functional group, is a phenylalanine that is generated from the naturally occurring auxin, which is extensively present in plants. The most promising outcomes in the battle against cancer and microbes …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 68–78 Read article
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Review on Clinical Safety and Efficacy of Giant Calotropis in the 21st Century
Abstract: Calotropis gigantea, a highly valued plant in traditional Indian pharmacology, has emerged as a promising candidate for therapeutic innovation. This review delves into the clinical safety and efficacy of C. gigantea in the 21st century, examining its historical use, phytochemical composition, and pharmacological properties. While traditional medicine has long utilized C. gigantea for various ailments, modern research has sought to validate these claims through scientific investigation. This review critically analyzes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 26–34 Read article
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Phytochemical Screening and Biological Activity of Pomegranate Extracts
Abstract: Pomegranates are renowned for their abundance of bioactive compounds that exhibit potent antioxidant, anti-inflammatory, and antimicrobial properties, making them a subject of growing interest in natural medicine. This study aimed to compare the biological activities of ethanolic extracts derived from different parts of the pomegranate plant—specifically, the bark, peel, and leaves. A comprehensive investigation was conducted to evaluate their phytochemical composition and assess their antimicrobial, antioxidant, and anticancer properties. The …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 64–79 Read article
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A Factualistic Study of Phytomedicinal Activity of Curcuma longa (Haldi): Plant That Infuses Life
Abstract: Curcuma longa, commonly known as turmeric, is a plant of remarkable medicinal significance that has been utilized for centuries in traditional medicine and has garnered considerable attention in modern scientific research. This review explores its extensive phytomedicinal potential, focusing on the plant's bioactive compounds, particularly curcumin, which is recognized as the primary agent responsible for its therapeutic properties. Turmeric contains an array of chemical constituents, including curcuminoids, volatile oils, and …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 14–24 Read article