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Research and Reviews: A Journal of Pharmacology Review Article

Review on Clinical Safety and Efficacy of Giant Calotropis in the 21st Century

  1. Mohd. Wasiullah Dept. Principal, Dept.of Pharmacy, Prasad Institute Technology, Jaunpur
  2. Piyush Yadav Dept. of Pharmaceutical Chemistry, Dept.of Pharmacy, Prasad Institute ofTechnology, Jaunpur
  3. Arjun Yadav Dept.of Pharmacy, Prasad Institute of Technology, Jaunpur

Abstract

Calotropis gigantea, a highly valued plant in traditional Indian pharmacology, has emerged as a promising candidate for therapeutic innovation. This review delves into the clinical safety and efficacy of C. gigantea in the 21st century, examining its historical use, phytochemical composition, and pharmacological properties. While traditional medicine has long utilized C. gigantea for various ailments, modern research has sought to validate these claims through scientific investigation. This review critically analyzes the available clinical evidence, highlighting the plant’s potential in managing conditions like inflammation, pain, and microbial infections. However, it also underscores the need for further rigorous clinical trials to establish definitive conclusions regarding their safety and efficacy. Additionally, the review discusses potential toxicity concerns associated with C. gigantea, emphasizing the importance of appropriate dosage and administration. In final analysis, C. gigantea demonstrates potential as a therapeutic agent, but ongoing research is vital to elucidate its therapeutic efficacy and safety profile, thereby facilitating its responsible and effective utilization in healthcare settings.

Keywords

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