Research and Reviews: A Journal of Pharmacology
Volume 15, Issue 1 (2025)
Table of contents
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Enhancing Patient Safety: A Study On Adr Monitoring In Tertiary Care Hospitals
Abstract: Background: Adverse drug reactions (ADRs) are a major concern in healthcare, causing patient morbidity and mortality. The objective of this study was to investigate the adverse drug reactions in a tertiary care hospital. Methods: From January to July 2024, an observational study was carried out at Bangalore's Akash Super Specialty Hospital. 51 individuals had their demographics, medications, and suspected adverse drug reactions (ADRs) gathered. The Naranjo scale was used to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 1–7 Read article
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A Comprehensive Review on Pharmacological and Therapeutic Uses of Azadirachta Indica in the Treatment of Various Diseases
Abstract: In ancient medicine, the majority of illnesses were treated with plants and phyto-compounds. The most beneficial traditional medicinal plant is Azadirachta indica (Neem). In Ayurveda, it has several therapeutic effects. One of the most adaptable medicinal herbs, it exhibits a broad range of biological action. It possesses medicinal qualities, including anti-microbial, and high efficacy and safety agents. The biologically active components of this plant have a wide range of uses. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 14–25 Read article
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Review on Clinical Safety and Efficacy of Giant Calotropis in the 21st Century
Abstract: Calotropis gigantea, a highly valued plant in traditional Indian pharmacology, has emerged as a promising candidate for therapeutic innovation. This review delves into the clinical safety and efficacy of C. gigantea in the 21st century, examining its historical use, phytochemical composition, and pharmacological properties. While traditional medicine has long utilized C. gigantea for various ailments, modern research has sought to validate these claims through scientific investigation. This review critically analyzes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 26–34 Read article
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From Clinic Formulation to Development of Acebrophylline
Abstract: Acebrophylline, a commonly utilized bronchodilator with anti-inflammatory properties, has become a key therapeutic option for managing respiratory conditions like asthma, chronic obstructive pulmonary disease (COPD), and chronic bronchitis. This review explores the journey of Acebrophylline from its clinic formulation to its development and commercialization, focusing on the key aspects of formulation strategies, pharmacological properties, and regulatory considerations. The drug’s dual mechanism of action, which involves both bronchodilation and anti-inflammatory effects, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 35–48 Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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A Novel Frontier On Biofeedback Enhanced Psychological Wellbeing For Metabolic Health In Human
Abstract: This article explores the emerging field of biofeedback and its application in optimizing metabolic health. Biofeedback involves the use of technology to monitor physiological processes and provide real-time feedback to individuals, empowering them to regulate their bodily functions. We delve into various biofeedback modalities and their potential benefits in managing metabolic disorders such as diabetes, obesity, and metabolic syndrome. Additionally, we discuss the underlying mechanisms of biofeedback, its effectiveness in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 56–69 Read article
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The Function of Diuretics in Current Medical Practice and Prospective Advancements
Abstract: Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions, such as congestive heart failure and hypertension, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 70–75 Read article
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Navigating the Principles and Practice of Oral Anticoagulant Therapy: A Comprehensive Healthcare Guide
Abstract: Oral anticoagulant therapy plays a critical role in the prevention and treatment of thromboembolic disorders, including atrial fibrillation (AF), venous thromboembolism (VTE), and mechanical heart valve replacement. This research article aims to provide a comprehensive overview of the principles and practice of oral anticoagulant therapy, focusing on the mechanisms of action, pharmacokinetics, clinical indications, monitoring, and management of associated complications. The cornerstone of oral anticoagulant therapy includes vitamin K antagonists …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 76–82 Read article
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An Evidence Based Analytical Study on Capability of ChatGPT in Advanced AI Based Patient Drug Counseling
Abstract: The application of ChatGPT in providing drug counseling to patients offers the best approach to enhancing policies of healthcare support in decision-making. Aim and Objectives: The present study mainly involves an evaluation of the capability of ChatGPT in the management of drug counseling among patients suffering from various metabolic disorders. Methodology: The present study was a community-based interventional study conducted for a period of 12 months from October 2023 to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 8–13 Read article
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Pharmacogenomics in Anesthesia: Individualized Drug Responses
Abstract: Pharmacogenomics is the study of how a person’s genes influence how they react to medications. Pharmacology, the study of medications, and genomics, the examination of genes and their functions, merge in this field to develop safe, effective drugs that can be prescribed based on an individual’s genetic makeup. Pharmacogenomics examines how an individual’s unique genetic makeup can influence their responses to certain drugs. In anesthesia, where individual responses to pain …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 83–95 Read article