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499 articles for “significant association”
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Statistical Models for Predicting Genetic Variability and Disease Susceptibility
Abstract: Differences in genetics are key to understanding why some individuals are more prone to certain diseases than others. Recent advancements in genomic research, combined with statistical modeling techniques, have made significant strides in predicting disease risk based on genetic factors. This review explores the application of statistical models for predicting genetic variability and their role in disease susceptibility. We discuss traditional methods like linear regression and genome-wide association studies (GWAS), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 30–34 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Evaluation of Chemical Constituents of Terminalia Arjuna Bark: As a Cardio-Protective Agent
Abstract: In the past, the primary source of medicinal agents was herbal remedies. One such medicinal plant that is well known for its many therapeutic benefits, particularly its cardiovascular effects, is Terminalia arjuna (TA). The therapeutic effects of these substances are due to a wide range of natural chemical compounds, such as flavonoids, polyphenols, triterpenoids, tannins, glycosides, minerals, proteins, and others. These compounds work together to provide the health benefits associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 1–6 Read article
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Fuzzy Probability Distributions and Their Applications in Uncertain Data Analysis
Abstract: This study explores the use of fuzzy probability distributions in data analysis under uncertain conditions, with a specific focus on their implementation in evaluating call center customer satisfaction. Traditional probability models rely on precise parameters, often failing to account for the inherent variability and subjectivity present in real-world data. In contrast, fuzzy probability distributions, which integrate fuzzy logic principles, offer a more adaptable and realistic framework for addressing such complexities. …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 · pp. 1–8 Read article
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Association of Vitamin D Binding Protein BP rs2282679 Gene Polymorphism and Serum Levels of Vitamin D in Patients with Vitiligo
Abstract: For vitamin D to have an impact, the vitamin D receptor (VDR) must be expressed and activated in the nucleus. The VDR has several known genetic variants. Biological impacts can be caused by changes in DNA sequences known as "polymorphisms" that are common in the population. Vitiligo is a disease that causes loss of skin color in patches, and it is a chronic (long-lasting) autoimmune disorder loss of color. The …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 45–52 Read article
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Performance Comparison of Noise-Tolerant, High- Performance CMOS Domino Logic Configurations
Abstract: In high-performance VLSI chip design, domino logic configuration is often preferred over static logic due to its faster operation and smaller area footprint, especially in deep submicron (DSM) technology. However, DSM noise has become a significant challenge in domino-based circuits, leading to compromises in the reliability and signal integrity of integrated circuits (ICs). The switching threshold of domino logic, defined as the input voltage level at which the gate output …
Published in Journal of Semiconductor Devices and Circuits · Vol. 12, Issue 2, 2025 · pp. 35–50 Read article
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Persistent Atmospheric and Ecosystem Impacts of Enteric Methane Emissions from Intensive Livestock Production Systems
Abstract: Enteric methane emissions from intensive livestock production systems exert a significant long-lasting influence on atmospheric stability and ecosystem integrity. Recent observations confirm that global methane emissions continued to rise through the early 2020s, with total emissions exceeding 620 teragrams per year by 2024, driven by expanding ruminant production and associated feed systems. Anthropogenic sources accounted for more than 330 teragrams per year, reflecting sustained growth in agricultural and fossil fuel …
Published in International Journal of Atmosphere · Vol. 2, Issue 2, 2025 · pp. 18–38 Read article
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AI and ML in the Chemical Industry: A Review of Transformative Applications and Future Prospects
Abstract: The chemical industry, a key growth indicator of the global manufacturing ecosystem, is experiencing a digital transformation driven mainly by advancements in Artificial Intelligence (AI) and Machine Learning (ML) in this sector. These technologies are totally revolutionizing current and traditional methodologies by significantly improving process efficiency, reducing costs of manufacturing, accelerating R&D, and improving safety and sustainability standards. Proper utilization of Artificial intelligence (AI) and machine learning (ML) in chemical …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Optimizing Power Generation from Building Ventilation Systems: A Study on Exhaust Fan Efficiency
Abstract: Due to population growth, the world's energy consumption has increased dramatically in both wealthy and developing nations in recent years, and by 2042, it is predicted to have doubled or more. Since a few years ago, the use of innovative sustainable power sources to meet energy demands has been gradually increasing. We've chipped away at a different idea because of this. As an alternative energy source, renewable energy (RE) resources …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 2, 2023 · pp. 22–27 Read article
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Study of Algebraic Structures in Discrete Mathematics and Its Applications
Abstract: Algebraic structures such as groups, rings, fields, semi groups, and lattices form the foundational framework of discrete mathematics. These structures are defined by specific sets and operations that follow algebraic laws, enabling a systematic approach to problem-solving in various domains. This paper explores the theoretical principles of these algebraic systems and highlights their vital role in computer science, cryptography, automata theory, coding theory, and software engineering. By examining their properties …
Published in Emerging Trends in Symmetry · Vol. 1, Issue 1, 2025 · pp. 35–40 Read article
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Enhancing Trust in Education Through Blockchain- Based Credential Authentication
Abstract: Academic credentials such as degree certificates, transcripts, and course completion records are fundamental for validating an individual’s educational achievements. However, conventional credential management systems largely rely on centralized databases and physical documentation, making them vulnerable to forgery, unauthorized modification, data loss, and inefficient verification processes. These limitations reduce trust among educational institutions, employers, and learners, while also increasing administrative overhead. This study proposes a blockchain-based credential authentication framework designed to …
Published in Journal of Computer Technology & Applications · Vol. 17, Issue 1, 2026 · pp. 1–7 Read article
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Rethinking Stocking Density in Broilers: Assessments of Physiological, Behavioral, and Environmental Impacts
Abstract: High stocking density in broiler production is a common practice aimed at maximizing space utilization and economic returns. However, it poses significant challenges to the performance, health, and welfare of the birds. This study explores the multifaceted impacts of elevated stocking density on broiler chickens, highlighting the physiological, behavioral, and environmental factors that deteriorate their overall well-being. Increased stocking density is associated with reduced growth rates, poor feed conversion efficiency, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 Read article
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Determining the Root Causes of Complications in Hemodialysis Maintenance Therapy
Abstract: As with peritoneal dialysis and kidney transplantation, hemodialysis has been considered one of the most effective therapies for the replacement of kidney function. While this helps to save patients with the disease by decreasing morbidity /mortality/ rates, this medication has some side effects. These may manifest during the dialysis process alongside the ongoing treatment. Avoiding these barriers becomes crucial for improving the patients’ prognosis in this context.We are going to …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 27–47 Read article
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Japanese Encephalitis and Dengue Fever Co-infection
Abstract: Dengue virus (DENV) and Japanese encephalitis virus (JEV) are two significant pathogenic viruses that can cause severe encephalitis. Dengue and Japanese encephalitis are vector-borne illnesses.Arboviruses that are carried by mosquitoes are significant India's causes of death and morbidity The rainy season, when the vector population grows, is when both dengue and Japanese encephalitis transmissions peak. We still don't fully understand how the CNS is involved in dengue and Japanese encephalitis …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Carbon Sequestration in Mineralogy: Potential of Ultramafic Rocks for CO₂ Storage
Abstract: The increasing concentration of atmospheric carbon dioxide (CO₂) due to anthropogenic activities has necessitated the development of effective carbon sequestration strategies. Mineral carbonation, particularly utilizing ultramafic rocks, has emerged as a promising approach for long-term CO₂ storage. This review explores the potential of ultramafic rocks in sequestering CO₂, discussing their mineral composition, reaction mechanisms, advantages, and challenges associated with their utilization in carbon capture and storage (CCS). Additionally, advancements in …
Published in International Journal of Minerals · Vol. 2, Issue 1, 2025 · pp. 30–35 Read article
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Outward Material Storage Area and Dispensing Activity for Packaging Material Area
Abstract: Efficient management of outward material storage and packaging material dispensing is essential for maintaining product quality, regulatory compliance, and streamlined operations in manufacturing industries. This review examines the principles, practices, and challenges associated with the design, organization, and control of outward material storage areas, with a specific focus on packaging material handling. Key aspects discussed include layout optimization, material segregation, environmental controls, documentation practices, and adherence to Good Manufacturing Practices …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 27–32 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Railway Track Safety System
Abstract: Railway Track Safety System (RTSS) is a comprehensive monitoring system specifically designed for the Indian railways. It consists of three subsystems that target specific challenges faced by the railways. Our main focus is on addressing four key problems. The first two issues involve cracks in the rails and foreign objects on the tracks. Cracks can occur naturally or be intentionally created to derail trains. Objects like stones can accidentally roll …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 1, 2024 · pp. 29–33 Read article
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Effect of Mindfulness, Meditation, Yoga on Mental Health
Abstract: In the last few years to improve quality of life importance has been given to the alternative method of therapy. Yoga, Meditation and Mindfulness has a positive impact on mental well-being. These alternate therapies of healing which help in self-healing tendencies. These alternate ways are both safe and effective treatment and it helps to stimulate positive thinking, destress, resilience, improved interpersonal relationships and increased productivity. Yoga, Meditation and Mindfulness has …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 73–78 Read article
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Prospective Evaluation of the Optimal Concentration and Effect of Epinephrine as an Adjuvant to Local Anesthetics for Prolonging Block Duration and Reducing Systemic Toxicity in Outpatient Surgery
Abstract: Purpose: To evaluate the optimal concentration and effect of epinephrine as an adjuvant to local anesthetics for prolonging block duration and reducing systemic toxicity in outpatient surgery. Methods: The study involved a randomized double-blind clinical trial on 80 adult patients awaiting day-care extremity surgery. The patients were randomly assigned to two groups of equal size. One group, Group E, was given the local anesthetic agent along with epinephrine as an …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 64–69 Read article