Search
260 articles for “stability challenges”
-
Space Pharmacy for Human Space Exploration: Overcoming Drug Stability, Packaging Challenges, Pharmacokinetic Variations, and Developing Innovative On-Demand Therapeutic Solutions for Long- Duration Missions Beyond Earth
Abstract: As humankind prepares for prolonged space exploration and the establishment of lunar and Martian habitats, ensuring reliable access to safe and effective medicines has emerged as a critical challenge. The evolving discipline of space pharmacy addresses the unique pharmaceutical needs of astronauts in microgravity and radiation-rich environments, where drug stability, packaging, and pharmacokinetics are markedly different from conditions on Earth. Traditional dosage forms often undergo accelerated degradation, while altered fluid …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 32–47 Read article
-
A Brief Review on Perovskite Materials: Synthesis, Properties, and Applications
Abstract: Perovskite materials have emerged as a transformative class of compounds, capturing widespread interest due to their remarkable properties and diverse applications across various fields, including optoelectronics, catalysis, energy storage, and environmental technologies. The synthesis techniques, classification, and unique properties of perovskite materials are thoroughly examined in this paper, which highlights the materials' potential to completely transform a number of sectors. One of the standout features of perovskites is their highly …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 42–49 Read article
-
Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
-
A Review on Energy Storage System Enhancing the Stability of Micro grids
Abstract: Microgrids constitute decentralized energy systems that rely on various distributed renewable energy sources (DERs), such as solar panels, wind turbines, and power and heat production plants. Energy Storage Systems (ESS) help improve the stability and reliability of microgrids by decreasing the intermittent nature of renewable energy sources. This analysis examines how microgrids are classified and how ESS might help improve power quality and system dependability. It explores the many stability …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
-
Nanoparticle and Lipid-Based Vaccine Delivery Systems: A Systematic Review of Platforms, Stability, Pharmacokinetics, and Immune Modulation
Abstract: The rapid evolution of vaccine technologies over the past decade has highlighted the transformative role of nanoparticle (NP) and lipid-based delivery systems in modern immunization practices. These platforms – including polymeric nanoparticles, lipid nanoparticles (LNPs), liposomes, nanoemulsions, and solid lipid nanoparticles (SLNs) – enable enhanced antigen stability, improved cellular uptake, targeted antigen delivery, and potent immune activation. This systematic review critically examines the physicochemical foundations, manufacturing approaches, stability challenges, pharmacokinetic …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 18–36 Read article
-
Comparative Assessment of Polymers and Composites for Solar Panels: Fundamentals, Performance Metrics, Manufacturing, and Sustainability
Abstract: This paper presents a comprehensive review of the main types of Photo Voltaic polymers and composites such as crystalline silicon (both mono- and poly-Si), thin-film tech (CdTe, CIGS, a-Si), perovskites, and organic/dye-sensitized cells and analyses the parameters such as efficiency, fill factor, open-circuit voltage, temperature response, and degradation. The analysis focusses on polymers and composites and manufacturing techniques like vapor deposition, roll-to-roll printing, and both solution and vapor techniques for …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 120–130 Read article
-
Thin Film Solar Cells: Progress in Materials, Fabrication, and Efficiency Enhancements
Abstract: Thin film solar cells (TFSCs) have drawn a lot of interest because of their potential for efficient and reasonably priced photovoltaic energy conversion. Their flexibility, low weight, and lower material consumption make them a desirable substitute for conventional solar cells made of crystalline silicon. This review explores recent advancements in TFSC technology, with a focus on materials, fabrication techniques, and efficiency improvements.Various thin-film materials, such as amorphous silicon (a-Si), perovskite, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 37–42 Read article
-
Nano-Materials in Vaccine Formation and Chemical Formulae’s for Vaccination
Abstract: For centuries, vaccines have been a cornerstone of public health, preventing debilitating and deadly diseases. However, the development and delivery of effective vaccines have always been met with challenges. From stability issues and limited immune response to the need for specific targeting, scientists are constantly seeking innovative approaches to improve vaccine efficacy and accessibility. Enter nanomaterials – minuscule materials with dimensions at the nanoscale – offering a powerful toolkit to …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 27–39 Read article
-
Unveiling the Veil of Black Money Understanding Its Impact on Economic Stability and Policy Formulation in India
Abstract: The issue of black money has emerged as a critical concern for India, undermining economic stability and challenging the effectiveness of policy formulation. Black money, generated through unaccounted income and tax evasion, exerts a detrimental influence on multiple facets of the economy, including resource allocation, income distribution, and public trust in governance. This study examines the multifaceted impact of black money on India’s economic framework, highlighting its role in distorting …
Published in Recent Trends in Social Studies · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
-
LQR-Based Optimal Control of Inverted Pendulum System with State Estimation and Stability Analysis
Abstract: The inverted pendulum on a cart is a canonical benchmark problem in control systems engineering, capturing the essential challenges of stabilizing an inherently unstable, underactuated, and nonlinear plant. Classical Proportional-Integral-Derivative (PID) controllers, while widely employed in industrial practice, exhibit fundamental performance limitations when applied to such systems, primarily due to their inability to account for multivariable coupling, process noise, and the absence of a systematic optimization framework. This paper presents …
Published in International Journal of Advanced Control and System Engineering · Vol. 4, Issue 1, 2026 · pp. 31–43 Read article
-
Innovations and Comparative Analyses in Foam Concrete: A Review of Emerging Techniques and Materials
Abstract: Foam concrete, recognized for its lightweight and eco-friendly properties, is gaining prominence as a sustainable construction material. However, challenges such as low mechanical strength, performance variability, and limited environmental resistance have prompted significant innovations in recent years. This study synthesizes findings from three key studies focused on enhancing foam concrete’s performance through nanomaterials, natural fibers, and alternative lightweight aggregates. The incorporation of nano-silica and nano-calcium carbonate into coal gangue foam …
Published in Trends in Transport Engineering and Applications · Vol. 12, Issue 3, 2025 Read article
-
A Review on Microbial Enzymes in the Food Industry: Current Innovations and Future Prospects
Abstract: Over the past few decades, microbial enzymes have become indispensable biocatalysts in food production, fundamentally revolutionizing how we approach manufacturing processes while simultaneously enhancing the quality of what we produce. Today, approximately 200 of the 4,000 known enzymes are deployed commercially with proteases, amylases, lipases, and lactases leading the charge in industrial food applications. This review brings together the latest innovations in how we use microbial enzymes for food processing, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 43–53 Read article
-
Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
-
NanoLEDs The Next Frontier in Optoelectronic Devices
Abstract: Purpose: This study investigates the advancements in NanoLED technology, particularly focusing on their materials, fabrication techniques, and optoelectronic properties. NanoLEDs hold immense potential in revolutionizing display technologies, yet their commercialization faces several challenges. By addressing the gaps in this area, the study aims to deepen the understanding of NanoLED applications, from high-resolution displays to novel devices in wearable electronics and optoelectronics. Design/Methodology/Approach: The review synthesizes recent innovations in NanoLED development, …
Published in Trends in Opto-electro & Optical Communication · Vol. 14, Issue 3, 2024 · pp. 28–33 Read article
-
Polymer Nanocomposites As Emerging Platforms in Pharmaceutical Nanotechnology
Abstract: Nanotechnology allows the handling of materials in the 1–100 nm range, where distinct physicochemical phenomena, including quantum effects and higher surface-to-volume ratio, enable disruptive uses in pharmaceuticals and biomedicine. Significant challenges in solubility, stability and targeted biodistribution of therapeutics can be overcome by incorporating nanostructured polymers and polymer-based composites into drug delivery systems. PLGA nanoparticle and other nanocarriers, such as PLGA micelles, dendrimers, and hydrogels, have revealed promising effects on …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 268–278 Read article
-
Power Quality Improvement in Grid-Connected PV Systems using TCSC
Abstract: Power quality issues such as voltage sags, swells, and harmonic distortions pose significant challenges to the stability and efficiency of grid-connected systems. This study presents a simulation and analysis of a Thyristor-Controlled Series Capacitor (TCSC) for mitigating voltage sags and swells, thereby enhancing overall power quality. A grid-connected photovoltaic (PV) system integrated with a TCSC is modelled and simulated using MATLAB/Simulink to evaluate its performance under diverse operating conditions. The …
Published in Trends in Electrical Engineering · Vol. 14, Issue 3, 2024 Read article
-
Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
-
Flame-Retardant Polymeric Materials: Recent Advances and Future Directions
Abstract: This review explores essential flame-retardant polymers that play a vital role in various industries such as electrical & electronics, automobile, manufacturing, and firefighting. This review also highlights the latest progress in the design and synthesis of flame-retardant polymers, highlighting novel approaches such as the incorporation of nanomaterials, bio-based flame retardants, and the use of intumescent systems. Recent advancements include high-throughput screening, computational design, bio-based and sustainable flame retardants, self-healing materials, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 125–132 Read article
-
Advancements in Humanoid Robot Locomotion: A Review of Control Strategies and Kinematic Models
Abstract: Humanoid robot locomotion has significantly improved over the past few decades, driven by improvements in control strategies and kinematic models. Researchers aim to develop robots that can walk, run, and navigate complex terrains with efficiency and stability. This review explores recent developments in humanoid locomotion, highlighting control strategies such as model predictive control, reinforcement learning, and central pattern generators. Additionally, it examines kinematic models, including inverted pendulum models and zero …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 1, 2025 · pp. 24–30 Read article
-
An Overview Mechatronics Systems Design of Modelica-Based Model Predictive Control Strategies for CO₂ Heat Pump Systems
Abstract: The growing adoption of renewable energy technologies poses challenges to energy supply stability, necessitating increased flexibility in energy demand. This paper introduces a Modelica-based Model Predictive Control (MPC) strategy aimed at keeping the supply water temperature within the range of 55°C to 75°C while minimizing energy consumption and electricity expenses throughout a year. A comprehensive, high-fidelity model representing a school building in Oslo, Norway, was developed using Modelica and exported …
Published in Journal of Mechatronics and Automation · Vol. 13, Issue 1, 2026 · pp. 15–27 Read article