Search
24 articles for “alanine”
-
Ferrocenium Ion Encapsulated Montmorillonite Clay as a Voltammetric Sensor for Distinguishing Amino Acids Glycine and Alanine
Abstract: Detection and determination of small bio-molecules and metal ions are of great importance for diagnosis of a number of diseases and understanding environmental pollution leading to extensive research on development of sensors. Among different sensors, electrochemical sensors are unique because of simplicity, low cost, easy maintenance and easy in vivo applications. Voltammetric sensor, one of the major constituents of electrochemical sensors, is essentially a surface modified working electrode (WE). The …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 1, 2018 · pp. 8–11 Read article
-
Influence of Methanolic Extractives of Prepupal Stages of Black Soldier, Hermetia Illucens L. (Diptera: Stratiomyidae) on the Biochemical Parameters of Serum and Liver in the DMBA Induced Toxicity in Norwegian Rat, Rattus Norvegicus (L)
Abstract: The larvae of Black soldier fly (BSF), Hermetia illucens L., are reducing the environmental pollution through utilization of organic waste for their development on organic wastes and converting the organic waste into protein and fat rich biomass. Health promoting potentials of black soldier fly derived proteins as ingredient of diet appears to be crucial need of modern days. In present attempt, forty Norwegian Rats were utilized as experimental animals. The …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 12, Issue 3, 2021 · pp. 1–19 Read article
-
Assessment of Hepatic Damage in Labeo rohita (Hamilton, 1822) Exposed to Azo dye C. I. Direct Green 6
Abstract: Textile industries are one of the major backbones of Indian economy. They are the major reason for contamination of water bodies and their toxicity to ecosystem is an alarming environmental issue. The present study was designed to evaluate the hepatotoxic effects of C.I. Direct Green 6 (DG 6), a commercially used textile azo dye on Labeo rohita fingerlings. For this, L. rohita fingerlings were exposed to three sublethal concentrations (2.5, …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
-
Synthesis, Characterization, Biological evaluation, and in silico study of aniline derivatives
Abstract: In many hospitals worldwide, bacterial infections brought on by resistant strains are wreaking havoc, particularly in patients who are already impaired by age, disease, and other conditions. Due to the bacterial resistance, it is required to search for newer antibacterial drugs or molecules. In the current study, we aimed to develop aniline derivatives, followed by their anti-bacterial and in silico studies. Out of all the synthesized derivatives, compound 4d was …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 25–32 Read article
-
Sublethal Toxic Effect of Paraquat Dichloride on Tissue Biochemical Markers in Labeo rohita
Abstract: The present study investigated the sublethal toxic effect of the commercial grade herbicide, Paraquat dichloride (24% SL), on Labeo rohita stressing the importance on biochemical parameters. Fishes were exposed to the sublethal concentrations of paraquat dichloride (5 μg/l and 10 μg/l) for 24 h in treated groups. Treated groups showed highly changed biochemical parameters on their exposure to the herbicide paraquat, when compared to the control. Tissues such as brain, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 11, Issue 2, 2021 · pp. 20–28 Read article
-
Effects of Plasticizer DI-(2 Ethylhexyl) Phthalate on Liver Enzymes of Adult Male Albino Rats
Abstract: AbstractDi-(2 Ethylhexyl) Phthalate (DEHP) is a common plasticizer used to make the plastic products more flexible. It is quite harmful as tested on other animal models and is carcinogenic too. The liver is the major organ for detoxification in body and is therefore affected first due to intake of any toxicant. The liver enzymes are good parameter to assess any such hepatic damage. In the present study, the acute toxicity …
Published in Research & Reviews : Journal of Ecology · Vol. 6, Issue 2, 2017 · pp. 6–9 Read article
-
Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
-
A Traditional Indian Unani Dynamic Drug Amla (Emblica Officinalis) And Its Unani Pharmacological Activities In The Light of Recent Experimental Studies: A Comprehensive Review
Abstract: Since ancient times, plants have been essential to human development, serving as a primary source of natural remedies. The challenges associated with producing synthetic medications, along with their potential side effects and high costs, have driven researchers around the world to focus on the study of medicinal plants. In recent years, numerous publications have highlighted the role of plant-derived bioactive compounds in treating a wide range of human ailments, underscoring …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 21–29 Read article
-
A Comprehensive Review of Therapeutic and Pharmacological Potential of Karafs (Apium graveolens)
Abstract: The history of the medicinal properties of plants and their use in various ailments is as old as the history of mankind. Karafs (Apium graveolens) is one of the important plants among them, belonging to the family Apiaceae/Umbelliferae. Its use in various ailments has been documented in Unani classical literature in detail. Every part of Karafs possesses wonderful medicinal properties. A series of studies conducted to evaluate its medicinal uses …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
-
Toxicological and Pharmacological Effect of Khadirarista in Animal Model
Abstract: AbstractThe objective of this study is to investigate the toxicological and pharmacological aspects of the popular Ayurvedic preparation Khadirarista (KDR). Khadirarista was administered orally to male albino rat. After 46 days of treatment period, animals were fasted for 18 h after the last administration. Biochemical studies including; total protein, serum albumin, blood urea nitrogen, bilirubin, creatinine, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase were conducted. Triglyceride and creatinine levels were …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 2, 2013 · pp. 61–67 Read article
-
Leucoanthocyanidin Reductase (LAR) Gene Analysisin Reductase
Abstract: Leucoanthocyanidin reductase (LAR) catalyzes the synthesis of catechin that is first step in PA biosynthesis. LAR involved in production of the flavan-3-ol. LAR gene is involved in proanthocyanidine production in several plants. Proanthocyanidins are plant secondary metabolites and occur in a wide range of plants and play an important role in defense against herbivores. The analysis of 50 proteins by global alignment of EF148325 with other ortholog sequences which have …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 2, 2013 · pp. 15–27 Read article
-
Seroprevalence of Hepatitis E Virus and Serum Level of Serum Aspartate Transaminase (AST) and Alkaline Phosphatase (ALP) Among Jaundice Patients in Kathmandu Valley, Nepal
Abstract: Hepatitis E is an acute disease caused by hepatitis E virus that usually manifest as acute jaundice. It is a waterborne infection and occurs sporadically or as epidemic outbreaks. Hepatitis E virus (HEV) is a positive-stranded RNA virus with a 7.2 kb genome with three open reading frames In this study we report the seroprevalence of HEV in different categories of jaundice patients along with their elevation of serum bilirubin, …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 37–42 Read article
-
Hepatoprotective Efficiency of Nigella sativa L. Extract on D-Galactosamine Induced Toxicity
Abstract: The Protective role of Nigella Sativa L. alcoholic extract (NSE) was investigated on D-Galactosamine (DGalN) induced hepatotoxicity in rats. Twenty four adult wistar albino rats were divided into four groups viz Control, D-Galatosamine induced hepatotoxicity, Nigella sativa alcoholic extract and Nigella Sativa alcoholic extract pretreatment prior to the administration of D-Galactosamine. After treatment, the rats were sacrificed, blood and liver samples were collected for determination of Serum Aspartate transaminase (AST), …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 39–44 Read article
-
Endosulfan-Induced Hepatotoxicity and its Amelioration by Administration of Bamboo (Dendrocalamus Strictus) Seed Extract in Rats
Abstract: Endosulfan is an important hepatotoxic agent that generates free oxygen radicals in liver and the incidence of toxic injury to the liver tissue in relation to its widespread has been reported. Bamboo is rich in phenolic components which possess various bioactivities and bamboo seed extract was found to have antioxidative properties. Hence, the present study has been designed to assess the protective role of bamboo seed extract against endosulfan induced …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
-
Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System
Abstract: Chiral compounds such as alanine amino acid and s-aminethylated L-cystiene derivatized with chiral reagents such as Marfey's reagents, 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosylisothiocyanate (GITC) and 2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosylisothiocyanate (BGIT), were achieved and separated by optimizing good methods using high performance liquid chromatography. Keywords: Derivatization, amino acid, chiral reagent, HPLCCite this Article Khlafulla Abdulrahim M, Maga Rajab A, Elmessmary Mohamad F. Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System. Research & …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 2, 2016 · pp. 39–43 Read article
-
Polyphasic Characterization and Comparative Genomics of a Newly Isolated Strain of Kocuria soli from Wild Ass Sanctuary, Gujarat, India
Abstract: From soil sample collected from Little Rann of Kutch-Wild Ass Wild Life Sanctuary, Gujarat a bacterial strain that is non-motile, cocci in shape, obligate aerobic, gram positive, catalase and oxidase positive was isolated and named as strain JC486. Strain JC486T was related to Kocuria soli M5W7-7T (99.7%) belonging to genus Kocuria according to sequence similarity and comparison data of 16S rRNA gene. The strain JC486T had a G+C content (DNA) …
Published in Journal of Water Pollution & Purification Research · Vol. 9, Issue 3, 2022 · pp. 16–22 Read article
-
A Method of Universal Primer Design for The Detection of Diverged CTX-M Beta-Lactamases in Multi-Drug Resistant Superbugs
Abstract: Complexity of many diverged β-lactamases in common multi-drug resistant bacteria has reached very high level. We found >40% of common bacteria in Kolkata water bodies were ampicillin resistant and reported clinical isolates were >95% ampicillin resistant worldwide. More than twenty unique sequence classes of β-lactamases were known to cause MDR inactivating penicillin, cephalosporin and carbapenem drugs. Further, there are other diverged MDR genes like drug efflux genes (acrAB, mexAB-EF, tetA), …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
-
Utilization of the Sibininto treat the DMBA Induced Hepatotoxicity and Free-Radical Damage in Norwegian Rat, Rattus norvegicus (L).
Abstract: DMBA is abbreviated form of the 7,12-Dimethylbenz[a]anthracene. It is working as immuno-suppressor. It also serves as a tumor initiator. It allows for a greatly accelerated rate of growth of tumor and making many cancer studies possible. The plant, Silybum marianum (L) yields pharmacologically active compound named as silbinin. The silbinin deserve documented antioxidant activity. The purpose of this study was to assess this silbinin for protective influence in DMBA induced …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 11, Issue 1, 2020 · pp. 26–36 Read article
-
Effect of Carbohydrates on Induction of Callus and Changes in Some Biochemical Parameters of Safflower (Carthamus Tinctorius L.)
Abstract: AbstractCarthamus tinctorius L. an oilseed crop is a member of the family Compositae or Asteraceae. Traditionally the crop was grown for its seeds used for colouring and favouring foods, in medicines and making red and yellow dyes especially before cheaper alanine dyes became available. For the last fifty years or so, the plant has been cultivated mainly for vegetable oil extracted from its seeds. This study describes the effect of …
Published in Research & Reviews : Journal of Botany · Vol. 3, Issue 1, 2014 · pp. 20–25 Read article
-
Hematological and Biochemical Changes in the Freshwater Fish, Pseudetroplus Maculatus Exposed to Sublethal Concentrations of Chlorpyrifos
Abstract: Sublethal effects of chlorpyrifos on hematological and biochemical parameters were assessed in the freshwater fish, Pseudetroplus maculatus. Fish were exposed to chlorpyrifos at two sublethal concentrations, 0.661 µg/L (one-tenth of LC50—96 h) and 1.32 µg/L (one-fifth of LC50—96 h), for 15 and 30 days maintaining the control group. Blood collected from the control and treated groups were used for analyzing the hematological and biochemical parameters. Chlorpyrifos exposure significantly (P<.05) decreased …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 108–116 Read article