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19 articles for “Neutrophil”
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Role of Human Neutrophils in Inflammation and its Modulation by Ixora coccinea
Abstract: Neutrophils are one of the key cells that actively participate in the innate immune reactions. Sequences of event of pathogen elimination by neutrophils are initiated with the activation of resting neutrophils. Pathogen is then eliminated by oxygen-dependent killing mechanism or oxygen-independent killing mechanism. This process includes margination, diapedesis, chemotaxis, phagocytosis and degranulation of neutrophils. Although, these mechanisms of the neutrophils are targeted to eliminate the pathogens and protect the body, …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 1, 2016 · pp. 32–48 Read article
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Clinical Significance of Immune Cells and T-cell Subsets in Lung Cancer
Abstract: Objectives: The aim of the study was to determine the clinical usefulness of pretreatment hematological parameters including neutrophils, lymphocytes, monocytes and immune T-cell subsets as well as calculated coefficients such as neutrophils-to-lymphocytes ratio(NLR),monocytes-to-lymphocytes ratio(MLR) and platelets-to-lymphocyte ratio(PLR)in patients with lung cancer. Materials and Methods: A total of 102 patients with lung cancer were prospectively analyzed. T-cell subsets were assessed by flow cytometry method. Peripheral blood was collected from 25 healthy …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 14–29 Read article
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Effect of Karpuradya Churna in the Treatment of Ekadosaja Type of Kasa
Abstract: Increasing globalization and urbanization leads changes in the environmental factor. The human are continuously attached with external environment through respiration and prone to diseases. Due to less resistance against disease causing organism and not adaptability against environment, leads to body protecting phenomenon produces cough. The aim is to study the effect of Karpuradya Churna on Ekdoshaja type cough. Thirty patients were selected from Arogyashala hospital Jaipur, with classical symptom of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 3, Issue 2, 2014 · pp. 17–28 Read article
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Exprimental Study on the Protective Action of rhGM-CSF for Acute Lung Injury
Abstract: Anti-cancer agents and radiation therapies result in various complications on respiratory systems like interstitial pneumonia, acute lung damage, bacterial pneumonia and pneumomycosis in clinical oncology. Recently it is being interested in variable rolls of GM-CSF to protect the lungs. We infuse the ethyl alcohol and lipopolysaccharide (LPS) to damage lung orally, and then inject GM-CSF subcutaneously at the same time and then observe the changes of lung tissue. As a …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 8, Issue 3, 2019 · pp. 4–8 Read article
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A Case with T-Cell Large Granular Lymphocyte Leukemia Accompanied with Persistent neutropenia without Anemia and Thrombocytopenia
Abstract: AbstractWe report a case of T-cell large granular lymphocyte (T-LGL) leukemia accompanied with persistent neutropenia without anemia and thrombocytopenia. A 47-year-old man was diagnosed as T-cell large granular lymphocyte leukemia by clinical feature, a persistent increase in the number of peripheral blood large granular lymphocyte and immune his to chemical analysis. He had the recurrent aphthous stomatitis persisting for more than 1 year. He showed neither lymph node swelling and …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 24–28 Read article
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The Relationship Between HbA1c and Inflammatory Markers in Acute Ischemic Stroke with and without Diabetes Mellitus
Abstract: Background: Diabetes mellitus (DM) is a prominent risk factor for acute ischemic stroke (AIS), contributing significantly to morbidity and mortality worldwide. Although inflammatory markers like neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP) are recognized as playing a role in the development of acute ischemic stroke (AIS), their association with diabetes mellitus (DM) in individuals affected by AIS remains uncertain. This study seeks to investigate the differences in …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 57–66 Read article
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Treatment of Korean Panax Ginseng against Cisplatin-Induced Toxicity in Rats Haematological and Histological Examination of Liver, Spleen and Kidney
Abstract: Vital goal of all anti-cancer therapies are to prevent the incidence of side effects either through more selective therapeutic methodology that target only neoplastic cells or through the use of complementary or alternative medicine. Present study investigated the effects of Panax ginseng (PG) on cisplatin-induced haematological and histopathological (liver, kidney and spleen) changes in rats. Rats were administered with PG (25, 50, 100 mg/kg) before or after an intraperitoneal injection …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 35–39 Read article
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Molecular Characterization of Respiratory Viral Infections and Co-Infections in Pediatric Patients Using FilmArray™ Multiplex PCR in a Tertiary-Care Hospital, South India
Abstract: Respiratory tract infections (RTIs) are a major cause of pediatric morbidity worldwide, with viruses, such as respiratory syncytial virus, rhinovirus/enterovirus, influenza virus, adenovirus, and parainfluenza virus, contribute significantly to hospitalizations. Conventional diagnostic methods often require prolonged processing times, which can delay clinical decision-making. Rapid molecular platforms, such as the FilmArray™ Panels, offer timely and comprehensive pathogen identification. This study aimed to evaluate the prevalence, seasonal trends, and co-infection patterns of …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 · pp. 57–66 Read article
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Effects of Gypsophila on Airway Inflammation in Guinea pig model of ovalbumin‐induced Asthma
Abstract: To look at how Gypsophlia (GSP) affects airway inflammation in a model of ovalbumin-induced asthma in guinea pigs (OVA).Methods: Using a random number table, sixty healthy female guinea pigs were split into six groups, each consisting of ten rats: the normal control, OVA, and GSP (0.45, 0.9, 1.8, and 3.6 g/kg). The ovalbumin and lipopolysaccharide sensitization approach was used to create the OVA guinea pig model. The GSP groups received …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 17–23 Read article
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Importance of inflammatory marker ratio and lipid profile ratio in Acute Ischemic Stroke
Abstract: Background: Acute Ischemic Stroke is a chronic inflammatory disease that is projected to be one of the leading causes of mortality affecting millions of people globally. It is essential to study the Platelet lymphocyte ratio (PLR), Neutrophil lymphocyte ratio (NLR) ratios and C reactive protein (CRP) in impacting the inflammatory status during stroke. It is also important that altered lipid metabolism could influence the inflammatory conditions associated with AIS. Hence …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 19–31 Read article
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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The Prognostic Efficacy of Inflammatory Indicators in Determining the Cause of Multiple Sclerosis Exacerbation
Abstract: Multiple sclerosis (MS) is the most prevalent immune-mediated inflammatory disease affecting the central nervous system, presenting with diverse clinical symptoms and manifestations. This study investigates the diagnostic potential of the monocyte-to-lymphocyte ratio (MLR), red cell distribution width-to-lymphocyte ratio (RLR), and systemic immune-inflammation index (SII) in detecting MS attacks among relapsing-remitting MS (RRMS) patients seeking care in the emergency department (ED). The research focused on RRMS patients who presented to the …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 1–8 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication
Abstract: Innate immunology represents the body's first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
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Effect of Polyherbal Formulation on Blood Biochemical Parameters in Post-Weaned Ghoongroo Piglets with Diarrhea in West Bengal
Abstract: Weaning condition is one of the critical and challenging phases of piglet where they get separated from mother and exposed to different environment. Sudden and abrupt changes in the total environment lead to the increase of physical stress that leads to various diseases, such as diarrhea, to the piglets. Use of phytogenic feed additives other than antibiotics is safe not only to the livestock, but also to the consumers and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 42–47 Read article
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Recent Advancement in Understanding the Aetiopathogenesis of Psoriasis: A Review
Abstract: Psoriasis is an immune-mediated inflammatory skin disease with periods of recurrence and remission. Various researches have globally explored the aetiopathogenesis of psoriasis but still it is not crystal clear. Abundant evidence suggest that dysregulation of immune cells in the skin, particularly keratinocytes, T cells, dendritic cells, natural killer cells, neutrophils, and macrophages play a vital role in the development of psoriasis. The combined effects of these cells explain most of …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 9–21 Read article
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Toxicity of Copper Sulphate on Behaviour, Hematological and Biochemical Parameters of Mrigal Cirrhinus mrigala
Abstract: The present study deals with the toxicity of copper sulphate on behavior, hematological and biochemical parameters of Mrigal Cirrhinus mrigala. Copper sulphate was prepared and characterized by using SEM, FTIR and XRD. The physic-chemical characteristics of water sample were analyzed before the experiment. The sub-lethal analysis on Cirrhinus mrigala in different concentrations such as 10–40 and 50 ppm of copper sulphate were used for a period of 96 h. Based …
Published in Research and Reviews: A Journal of Toxicology · Vol. 11, Issue 1, 2024 · pp. 26–32 Read article