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288 articles for “Genetic”
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Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19
Abstract: The COVID-19 pandemic has brought attention to the need for rapid, accurate, and scalable diagnostic techniques. Metagenomics, a powerful technique that enables the comprehensive analysis of genetic material from complex microbial communities, has emerged as a promising diagnostic approach for COVID-19. This article elucidates the principles of metagenomic sequencing, highlighting its ability to detect viral RNA directly from clinical samples without prior knowledge of the pathogen. Furthermore, we discuss the …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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A Study to Assess the Stress and Anger Management by Deep Breathing Exercise and Meditation Among Adolescent Nursing Students at a Selected Nursing School in Delhi
Abstract: Introduction: Stress is a response that can lead to physical, emotional, or psychological strain. It is a frequent occurrence in daily life. Stress acts as the body's natural mechanism for defense against potential threats and dangers. It initiates a release of hormones that ready the body's functions to either confront danger head-on or retreat, commonly known as the fight-or-flight reaction. Anger can be caused by both external and internal events …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 15–19 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Disease: A Major Stumbling Block in the Growth of Aquaculture
Abstract: Aquaculture plays a crucial role in ensuring food security, fostering economic development, and providing recreational opportunities worldwide. However, the intensification of aquaculture practices has led to a surge in environmental challenges, including water pollution, soil acidification, eutrophication, chemical contamination, and the spread of diseases. Among these, diseases caused by bacteria, viruses, fungi, and parasites pose significant threats to the sustainability of global aquaculture. Despite the implementation of various diagnostic methods …
Published in International Journal of Marine Life · Vol. 1, Issue 1, 2024 · pp. 25–28 Read article
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Hydroponics Culture Regulated Metabolic Variations in Plants of Medicinal Value
Abstract: The current review chiefly brings to light the importance of alternative cultivation strategies for medicinal plants about the effective enhancement of the bioactive substances. The fast-paced society is favoring the need for its cost-effective cultivation and studying the effects thereafter. The mis-steps while collecting the plant from the wild lead to identification issues, genetic and phenotypic variations, variable bioactive substances/secondary metabolites, and toxic compounds. So, cultivation happening in controlled environments, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 14–20 Read article
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Impact of Therapeutics on Carbapenem-Resistant Acinetobacter baumannii
Abstract: Acinetobacter baumannii, a formidable pathogen in healthcare settings, poses a significant threat due to its propensity to cause nosocomial infections. This bacterium exhibits several attributes that enable it to evade the human body's natural defenses. A. baumannii's remarkable adaptability is highlighted by its ease in acquiring antibiotic resistance determinants, rendering it challenging to treat. Its ability to thrive in hospital environments underscores the urgent need for stringent infection control practices …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Targeting Dystrophin Restoration and Neuroprotection in Duchenne Muscular Dystrophy: Insights from Withania somnifera
Abstract: Duchenne muscular dystrophy is a genetic disorder. This disease affects men more common than women. Main objective of the present study was to identify the naturally active phytocompounds from Withania somnifera (Ashwagandha). Ashwagandha has a great value in the field of Ayurveda and Indian medicine and is used for treating muscular and neurological disorders. Toxicity prediction, molecular docking, statistical information, drug illness prediction, and Absorption, distribution, metabolism, excretion, and toxicity …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 64–84 Read article
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Studies On The Length-Weight Relationship And Morphometric Characteristics of Rohu, Labeo Rohita (Hamilton) From Pond In Radhamohanpur, Jirania, Tripura, India
Abstract: The present study describes the length–weight (LWR) relationship and morphometric characters of 30 specimens of the rohu, Labeo rohita (Hamilton) collected from the pond situated in Radhamohanpur, Jirania, Tripura, India over a period of six months extending from (January 2020-June 2020). The fish were caught by traditional fishing gear. Total length (TL) reading has been taken from Vernier Calliper and Body weight (BW) measured with digital balance. The readings of …
Published in International Journal of Marine Life · Vol. 1, Issue 2, 2024 · pp. 27–34 Read article
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To Rule Out the Efficacy of Haridradi Drugs in Respiratory Allergic Disorders in the Childrens.
Abstract: Allergic diseases in children have increased significantly in recent years and they are a major cause of morbidity in the children. Although there is a genetic predisposition, exposure to allergens i.e pollens, irritants, infections, diets and inhalant will determine the sensitization. At present, the best approach to the children who are at high risk for the development of allergies is to introduce environmental and dietary control and adopt early measures …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 53–60 Read article
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Trauma- Its Transgenerational Inheritance and Associated Nuances in Perinatal Care: A Systematic Review
Abstract: The research is a systematic review of the existing clinical and animal studies pertaining to effects of trauma on immediate offsprings and its transgenerational inheritance. The research also summarises the current statistical data on perinatal care globally with special emphasis on India as a developing nation and the current strategies, government policies and international recommendations on maternal and child health as put forward in the Sustainable development goal 2030 by …
Published in International Journal of Children · Vol. 1, Issue 1, 2024 · pp. 37–45 Read article
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Association of Vitamin D Binding Protein BP rs2282679 Gene Polymorphism and Serum Levels of Vitamin D in Patients with Vitiligo
Abstract: For vitamin D to have an impact, the vitamin D receptor (VDR) must be expressed and activated in the nucleus. The VDR has several known genetic variants. Biological impacts can be caused by changes in DNA sequences known as "polymorphisms" that are common in the population. Vitiligo is a disease that causes loss of skin color in patches, and it is a chronic (long-lasting) autoimmune disorder loss of color. The …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 45–52 Read article
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Progeria Syndrome Unveiled: A Scientific Odyssey into Premature Aging Mechanisms and Therapeutic Frontiers
Abstract: Progeria, or Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare and fatal genetic disorder in childhood, exhibiting features akin to premature aging. Despite normal appearances in infancy, affected children face accelerated aging with distinct facial characteristics, including micrognathia, dental malformations, lower body weight, early hair loss, decreased joint mobility, lipodystrophy, etc. The cause of HGPS is a point mutation that occurs at the exon 11 of the LMNA gene which normally …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 52–68 Read article
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Angioedema-Diagnosis & Management
Abstract: Angioedema (AE) encompasses a diverse range of conditions categorized into three main groups: (1) angioedema mediated by histamine (AE-H); (2) angioedema mediated by bradykinin (AE-BK); and (3) angioedema with an unknown mechanism (AE-UNK). It can manifest on any part of the body, though commonly affected areas include the face, lips, mouth, throat, larynx, extremities, genital regions, and gastrointestinal tract. AE-H can occur by itself or in conjunction with chronic urticaria, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 9–21 Read article
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Bacteriophage Therapy in Dairy Farming: A Potential Alternative to Antibiotics
Abstract: The widespread use of antibiotics in dairy farming to control bacterial infections has led to significant challenges, including the emergence of antibiotic-resistant bacteria and concerns over antibiotic residues in milk. Consequently, there is an increasing demand for alternative approaches to control bacterial infections in dairy cattle. One promising solution is bacteriophage therapy, which uses viruses that selectively infect and destroy bacteria. As a result, the need for new strategies to …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–5 Read article
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Skin Cancer Detection System Based on Machine Learning for Recognition of Cancerous Images
Abstract: Skin cancer ranks among the most prevalent types of cancer globally and poses significant risks when left untreated. Skin cancer arises when abnormal cells proliferate uncontrollably in the skin. This uncontrolled growth can be triggered by genetic mutations, exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds, or various other factors. In this, the early detection of cancer plays a crucial role in treatment and …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Breast Cancer: Susceptible Genes and Significant Risk Factors
Abstract: Breast cancer is the most common malignancy affecting women globally. In 2012, around 1.67 million new cases were reported worldwide. With the increase in life expectancy in developed countries, the incidence of breast cancer among older adults has risen significantly. In 2017, an estimated 252,710 new cases of invasive breast cancer were recorded, along with 6,341 cases of breast cancer in situ in the USA. About 24% of all breast …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 36–43 Read article
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A Comprehensive Review on Long-term Care Policies for Intellectual and Developmental Disabilities
Abstract: Intellectual disability (ID) is a neurodevelopmental difficulty that affects both intellectual functioning and adaptive behaviour. The term IDD describes a broad range of long-term disorders that are caused by either physical or mental deficits. These disorders can influence numerous facets of life, such as self-care, social skills, communication, and education. This condition affects social and practical abilities daily. Conditions like cerebral palsy, Down syndrome, and autism spectrum disorder, Genetic predispositions, …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 2, 2024 · pp. 36–42 Read article
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Microalgae: Promising Sources of Biofuels
Abstract: Single-celled photosynthetic organisms known as microalgae have drawn a lot of interest as a potential source for the synthesis of biofuel. These microscopic organisms are able to effectively convert sunlight and carbon dioxide into biomass that is high in proteins, carbs, and lipids. Microalgae makes up to 19% starch concentration providing an eco-friendly and sustainable way to satisfy the growing need for renewable energy sources.Although they can be made from …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 3, 2024 · pp. 1–12 Read article
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Sustainable Livestock Management Practices: Reducing Environmental Impact, Improving Animal Welfare, and Increasing Productivity
Abstract: Sustainable livestock management is essential for addressing the increasing global demand for animal products while reducing environmental impact, safeguarding animal welfare, and sustaining productivity. This review explores sustainable approaches in livestock farming, emphasizing strategies to reduce environmental degradation, enhance animal welfare, and boost productivity. Environmental impacts, including greenhouse gas emissions, nutrient runoff, and water usage, present significant challenges. Sustainable practices such as efficient nutrient management, low-emission breeding, dietary interventions, and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 2, 2024 · pp. 23–27 Read article