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382 articles for “physical development”
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions. Methods: A total of …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Static Structural Analysis and Bridge Modeling Using ANSYS
Abstract: Structural analysis is a crucial discipline within civil engineering that ensures built structures are safe, durable, and capable of performing the functions for which they are intended. This scientific approach is essential for confirming that all safety requirements are met, thereby allowing structures to fulfill their purpose efficiently and economically over their design lifespan. The principles of structural analysis originate from the collaborative efforts of engineers across various domains, all …
Published in Trends in Transport Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 27–32 Read article
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Development and Characterization of a Solid Dispersion of an Anti-Diabetic Drug Using Pectin as a Natural Polymer
Abstract: Aim: The current study sought to improve the solubility and oral bioavailability of gliclazide by creating solid dispersions and oral dispersible tablets (ODTs) with enhanced physicochemical characteristics and maintained antidiabetic action. Methods: Preformulation studies were conducted to evaluate the physicochemical properties of gliclazide, including physical appearance, melting point, solubility, and partition coefficient. Solid dispersions were prepared using hydrophilic carriers-pectin and PVP K30, and subsequently characterized by Fourier Transform Infrared Spectroscopy …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Polymer-Coated Composite Granules of Clarithromycin: Design, Characterization, and Functional Evaluation for Taste Masking and Antibacterial Performance
Abstract: Background: Masking the unpleasant taste of clarithromycin is essential to improve patient adherence, especially among pediatric and elderly groups. However, enhancing palatability while maintaining its antibacterial effectiveness remains a significant formulation challenge. This study focused on developing polymer-coated clarithromycin granules (B1–B10) using novel non-sugar-based polymers and assessing their antibacterial activity against Staphylococcus aureus Methods: Clarithromycin granules were produced using a fluidized bed coating technique with non-saccharide polymers, specifically Eudragit E-100 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1042–1050 Read article
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Assessing Utility of Parks: A Study of Parks in Raipur, India
Abstract: With the rapid growth of urbanization in India, urban parks are taking center stage as vital recreational spaces and community gathering spots. As cities continue to densify and open spaces shrink, public parks increasingly serve as essential infrastructure that supports physical health, social interaction, and environmental well-being. In addition to offering leisure and recreation, urban parks contribute to urban resilience by improving microclimatic conditions and enhancing the overall quality of …
Published in International Journal of Urban Design and Development · Vol. 4, Issue 1, 2026 · pp. 42–57 Read article
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Assessment of Water Quality Deterioration in Sacred Ponds of Varanasi: Impact of Urbanization, and Pollution
Abstract: Water scarcity, pollution, political unrest, and population growth have made it imperative to manage water resources, including surface water, responsibly in the twenty-first century. The ponds deteriorate due to development, urbanization, and the burden of many polluting sources. Varanasi had roughly 110 pounds and kunds in the 1980s; today, there are only 56. The physical and chemical quality parameters of five significant sacred ponds that have existed in Varanasi from …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 2, 2024 · pp. 30–37 Read article
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Overview of Atomic Structure of Metals in Group 1 Elements
Abstract: This study discussed the basic atomic features of Group 1 elements—lithium, sodium, potassium, rubidium, cesium, and francium—by concentrating on their electronic configurations, atomic radii, and ionization energies. The article gives a thorough investigation of how these variables contribute to the chemical and physical characteristics of alkali metals. The data demonstrated that when the atomic number increases, the atomic radius likewise increases, whereas the ionization energy drops. These developments are ascribed …
Published in Journal of Materials & Metallurgical Engineering · Vol. 14, Issue 3, 2024 · pp. 6–13 Read article
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Architecture and the Human Lifespan
Abstract: For centuries, human beings have strived for only one thing in life: to live a long, happy life. From learning to hunt for food and protection, to developing villages and eventually skyscrapers, the goal has always been to live longer and happier. But what really makes humans live longer? Paper suggests that physical health, alone, is not the only contributing factor towards human lifespan. Living a long life consists of …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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Machine Learning Assisted Timing Violation Prediction in Sub-7nm VLSI Physical Design
Abstract: The continuous scaling of semiconductor technology into the sub-7nm regime has introduced significant challenges in timing closure due to process variability, interconnect delay, power density, and manufacturing uncertainties. Conventional static timing analysis techniques often require extensive computational resources and iterative optimization cycles, resulting in increased design complexity and longer turnaround time. This research proposes a Machine Learning Assisted Timing Violation Prediction framework for sub-7nm VLSI physical design to improve early-stage …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 4, Issue 1, 2026 Read article
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Risk Management in Civil Engineering by FTA, FMEA and Risk Matrix
Abstract: Infrastructure projects, particularly in civil engineering, are fraught with uncertainties that manifest as both physical and financial risks. The project report, titled Quantifying and Managing Financial and Physical Risks in Infrastructure Projects, aims to bridge the existing gap between managing these two critical categories of risks. By integrating advanced statistical methodologies such as Failure Mode and Effects Analysis (FMEA), Fault Tree Analysis (FTA), Risk Matrix, and Regression Analysis, this study …
Published in Journal of Structural Engineering and Management · Vol. 12, Issue 1, 2025 · pp. 34–46 Read article
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Exploring the Effectiveness of IoT in Virtual Doctor Robot Systems
Abstract: The design and development of a Virtual Doctor Robot (VDR) using Internet of Things technology is presented in this study with the goal of facilitating remote medical assistance. In light of the constraints associated with physical presence, especially in underprivileged areas like isolated parts of India during the COVID-19 pandemic, videoconferencing (VDR) is a viable means of bridging the gap between patients and physicians. The VDR makes accurate diagnostic and …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 3, 2024 · pp. 13–23 Read article
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Tactile Sensing Technologies in Robotics: A Review of Sensors, Materials, and Applications
Abstract: Tactile sensing, which closely resembles the human sense of touch, is an essential capability in modern robotics. It enables robots to detect and interpret physical interactions with objects, surfaces, and living beings, thereby allowing them to operate more intelligently and adaptively in complex environments. Unlike visual or auditory sensors, tactile sensors provide direct feedback about contact, pressure, texture, force, temperature, and even vibration. These sensory cues are vital for improving …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 1, 2025 · pp. 17–23 Read article
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The Evolution and Impact of Numbers: From Ancient Tallies to Quantum Computing: Review Article on Numbers
Abstract: Numbers are among the most fundamental constructs in human civilization, serving as the backbone of mathematics, science, technology, and virtually every aspect of daily life. They represent not only quantities and measures but also relationships, structures, and patterns that underpin the fabric of human understanding. From the earliest tallies etched on bones by prehistoric humans to the sophisticated numerical systems embedded in today’s artificial intelligence and quantum computing, the evolution …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 3, 2025 · pp. 15–19 Read article
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Development of Web-enabled Smart Hospital Management System: Patient Data Visualization and Real-time Decision Making
Abstract: As everyone is aware, fewer people had access to healthcare services, which prevented many people from receiving the care they needed. The idea that, by WHO criteria, there should be one physician for every 1,000 patients is nearly unbelievable. Yet, India’s current ratio is a staggering 1:1445. This disparity highlights a serious gap in healthcare resources that cannot be ignored. Authors remember speaking with a friend who works in a …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 3, 2024 · pp. 41–46 Read article
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Improving Indoor Room Air Conditioning Using PID Control
Abstract: Energy use in building air conditioning contributes significantly to power demand; therefore, in this work, we propose an improved methodology to achieve comfort conditions through PID control assistance. The project develops a mathematical model based on analytical heat transfer equations for comfort conditions by fulfilling the Fanger equation, considering environmental parameters (ambient temperature), metabolic rate, and people’s physical activity (internal heat generation) to reduce power consumption and improve energy efficiency. …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 12, Issue 1, 2025 · pp. 1–21 Read article
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Study of Modification of Butadiene-Styrene Rubber with Biopolymer
Abstract: This paper presents a detailed study aimed at the development of a new composite system based on butadiene-styrene rubber (BSR) and natural biopolymer wooden stone. The main goal of the work was the creation of a thermodynamically compatible material with improved ozone-resistant and physical-mechanical properties, able to function effectively in aggressive conditions, especially in the liberated areas of the Republic of Azerbaijan, where the requirements for the stability of materials …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 299–310 Read article
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An Analytical Study of the Effectiveness of the Child Development Scheme in Anganwadi Centers of Rudraprayag District
Abstract: From the perspective of human development, childhood is regarded as a highly sensitive and multidimensional phase that plays a pivotal role in shaping the trajectory of human life. During childhood, children undergo rapid growth across their mental, social, psychological, and physical domains. Currently, the mental, physical, and social well-being—as well as the overall health—of children remains a grave challenge for the entire world. An increase in nutritional and health-related problems …
Published in International Journal of Children · Vol. 3, Issue 2, 2026 · pp. 35–47 Read article
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The Effects of Physiochemical Parameters and Microbial Counts on Metal Coupons Corrosions in Freshwater Environment at Different Water Depths
Abstract: The effect of water quality on metal coupon corrosion was investigated at the New Calabar River in Choba. The study examined metal corrosion rates at five different depths: 30 cm, 60 cm, 90 cm, 120 cm, and 150 cm in a freshwater environment. Water samples were collected at each depth and analyzed for physicochemical and microbial parameters to understand their impact on metal degradation. Key parameters measured included pH, Electrical …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 2, 2025 · pp. 31–51 Read article
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Nano-Adsorbents for Water Purification: A Focus on Nanoclays
Abstract: Nanotechnology has emerged as a pivotal tool in addressing contemporary environmental challenges, particularly in water purification. This paper explores the use of nano-adsorbents, focusing on nano-clay materials, as effective solutions for the adsorption and removal of harmful pollutants from water. Nano-clays, owing to their large surface area and unique physicochemical properties, exhibit exceptional adsorption capacity for contaminants such as heavy metals, dyes, antibiotics, and various organic compounds. This review consolidates …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 3, 2024 · pp. 38–44 Read article