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634 articles for “B-Cell”
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Performance and Analysis of 6T, 8T & 10T SRAM Cell in 28nm Technology
Abstract: Technology scaling into deep sub-micron regimes has significantly increased the design challenges of Static Random Access Memory (SRAM), particularly at the 28 nm technology node. As transistor dimensions shrink, SRAM cells become more vulnerable to stability degradation, leakage current, process variations, and reduced noise margins, which adversely affect overall memory performance and reliability. The conventional 6T SRAM cell remains widely used due to its compact structure and high storage density; …
Published in Journal of VLSI Design Tools and Technology · Vol. 16, Issue 2, 2026 Read article
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A Rare Case of Serous Cystadenoma Ovary with Cholesterol Granuloma in an Adult Female
Abstract: In reaction to cholesterol crystals and foreign body giant cells, cholesterol granulomas are formed. These are the results of long-term inflammation brought on by the buildup of cholesterol crystals in tissues. The middle ear and paranasal sinuses are the most often reported locales; however, the mediastinum, breast, and ovary have all been implicated in a small number of cases. Here, we report a rare instance of an accidental ovarian cholesterol …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 13–17 Read article
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Mathematical Modelling on Unsteady Blood Flow and Unsteady Heat Transfer Through a Stenosed Artery with Hematocrit and Slip Velocity
Abstract: A theoretical investigation concerning variable viscosity dependent on percentage concentration of red blood cell interm of total volume of blood (hematocrit) and slip velocity on unsteady flow of blood and heat transfer has been carried out. The analytical expressions for the flow characteristics and the heat transfer rate, including the velocity profile, volumetric flow rate, flow resistance, wall shear stress, and temperature profile, were obtained using the weighted residual method, …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 2, 2025 · pp. 16–36 Read article
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Analysis of a Battery Pack Module for a Formula Student Car
Abstract: This research aims to evaluate the development of a high-voltage accumulator system that meets established standards of safety and operation. It examines key components, protocols, and techniques used in its creation while assessing performance in electronic cooling and structural integrity. Polymers, serving as electrical insulators and flame retarders, have found an interesting application in EV battery packs. This study focuses on polycarbonate materials' ability to withstand thermal and structural loads …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 320–339 Read article
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Immunological Mechanisms Underlying Autoimmune Disorders: Recent Advances and Therapeutic Implications
Abstract: A diverse range of illnesses known as autoimmune disorders are typified by dysregulated immune responses against self-antigens, which result in tissue damage and persistent inflammation. Understanding the genetic, epigenetic, and environmental variables that contribute to autoimmune pathogenesis has advanced significantly during the last ten years. Current disease models have been transformed by new understandings of immunological tolerance mechanisms such as the functions of regulatory T cells, cytokine networks, and the …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 21–25 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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TOXICOLOGY: Present-Day Difficulties for Investigating Safety Science and Target Safety Evaluation of Major Human Hepatocytes
Abstract: Preclinical toxicology has developed into a more thorough understanding of toxicity pathways from its descriptive beginnings. Technological developments have made it possible to forecast safety occurrences, mitigate adverse effects, and create safety biomarkers. Because they are able to self-renew and specialize into different types of human body cells, stem cells are currently being employed for in vitro toxicological applications. However, as compared to primary human hepatocytes, stem cell-derived HLCs perform …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 31–40 Read article
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Application of pET28a Vector for the Over Expression of Recombinant Human Tim23 Protein in E. coli and its Validation by Immunoblotting
Abstract: This study aimed to produce recombinant human Tim23 protein by molecular cloning, expression, and purification. Amplification of human TIM23 was carried out by polymerase chain reaction (PCR) and cloned into DH5α cells. The pET28a-human TIM23 was transformed into BL21DE3 and expressed the gene by IPTG induction. Recombinant pure human Tim23 antigen was prepared, and injected into rabbits and polyclonal antibodies were raised, which was confirmed by western blotting. The transformed …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 32–44 Read article
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Bacteriophage Therapy in Dairy Farming: A Potential Alternative to Antibiotics
Abstract: The widespread use of antibiotics in dairy farming to control bacterial infections has led to significant challenges, including the emergence of antibiotic-resistant bacteria and concerns over antibiotic residues in milk. Consequently, there is an increasing demand for alternative approaches to control bacterial infections in dairy cattle. One promising solution is bacteriophage therapy, which uses viruses that selectively infect and destroy bacteria. As a result, the need for new strategies to …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–5 Read article
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Hearing, Speech, and Language Characteristics in a Case with Hemoglobinopathy Secondary to Beta Thalassemia Intermedia
Abstract: Background: Thalassemia is an inherited disorder characterized by a reduced amount or absence of hemoglobin, the oxygen-carrying protein inside the red blood cell. Thalassemia has its types called alpha and beta-thalassemia. Beta thalassemia is a condition in which there is a reduction or deficit in the synthesis of the beta-globin chain of hemoglobin molecules caused by a mutation in chromosome eleven. Beta thalassemia can be broadly categorized into three main …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 1–5 Read article
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Current Drugs Target the EGFR
Abstract: Cancer is a devastating disease, but there have recently been significant advancements in therapy that have identified EGFR and its related proteins as valuable indicators and targets for treatment. The ERBB receptor tyrosine kinase superfamily includes EGFR, which is a transmembrane glycoprotein. When the EGFR receptor interacts to its particular ligand, EGF, it causes tyrosine residues to be phosphorylated and forms receptor dimers with other members of the receptor family. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–8 Read article
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Advances in Nanocellulose-Enhanced Polymers and Composites: Structure, Performance, and Applications
Abstract: The most common biopolymer is cellulose, which can be converted into nanocellulose (NC) the sustainable nanomaterial possessing the outstanding characteristic of biodegradability, renewability, low density, high aspect ratio, and excellent mechanical performance. Such distinctive features make NC a promising filler in polymer and composite systems. Recent developments in the preparation of nanocellulose using various natural and artificial sources have facilitated scalable production processes that have less energy requirements and are …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1610–1623 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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Effectiveness of a Video-based Teaching Program on Knowledge and Attitudes Toward Stem Cell Therapy Among Nursing Students
Abstract: Integrating stem cell therapy (SCT) into healthcare necessitates adequate training for nursing students to comprehend its principles and applications. This study evaluates the efficacy of a video-assisted teaching program (VATP) in enhancing knowledge and attitudes toward SCT among nursing students. A pre-test post-test quasi-experimental design was utilized with a sample of 100 nursing students. The participants were split into experimental and control groups. The experimental group received the VATP intervention, …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–8 Read article
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Design and Estimation of Biogas Plant For Canteen Waste: A Case Study of RD’s Rajgad Technical Campus, Dhangwadi, Bhor, Pune
Abstract: Today's economy and society rely on energy. In the end, conventional fossil fuels like oil will run out, and an alternate primary energy source will be required to close the widening gap between rising demand and declining supply. Biogas is a great energy source in light of rising petroleum prices, declining foreign exchange reserves, and the rupee-dollar exchange rate. Organic matter breaks down to produce biogas, a fuel. The primary …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 17, Issue 2, 2026 Read article
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Drive Line for Plug-in Electric Vehicle with PMSM Motor and Hydrogen Fuel Cell
Abstract: In the era of transportation, the best effort will be to replace conventional fossil fuels. Instead, the usage of fossil fuels will give way to renewable energy sources and other clean energies. Many institutions promote the developments and research in the area of hydrogen fuel cell development. This paper passes through the hydrogen fuel cell area as the primary source considered here is a hydrogen fuel cell. Since electric motors …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 32–49 Read article
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Long non-coded RNA, cancer, immune cells, tumor micro-environment, immuno-oncology, immune escape, cancer-immune cycle, lncRNA signature
Abstract: Developing data from current research reveals fresh insights into the roles played by long non-coding RNAs (lncRNAs) in immuno-oncology. Long non-coding RNAs (lncRNAs) not only influence the aggressiveness of cancer cells but also play a crucial role in controlling different immune cells and stromal cells, which in turn changes the tumor micro-environment and impacts anti-tumor immunity. The significance of predictive indicators derived from long non-coding RNAs (lncRNAs) is underscored by …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 7–26 Read article
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The Anhadnaad Universe
Abstract: Current Science considers that 95% universe is made of Dark energy and Dark Matter which are completely unknown entities and can’t be detected directly. Current Science also does not believe in independent existence of Consciousness on its own. It rather consider it as an outcome of electrical interaction in brain cells which means there are as many consciousnesses as the number of brains in the entire universe. But my theory …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 2, 2025 · pp. 19–29 Read article
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Advances in Polymer Chemistry for Zinc Oxide Nanoparticle-Based Composites in Moisture Sensing Applications
Abstract: In present scenario the application of Polymer chemistry is various domain. It is used in sensing the moisture. This paper explores the synthesis and application of zinc oxide nanoparticles (ZnO-NP) deposited on polymer-based hygroscopic substrates to enhance the dielectric properties of capacitive sensors. The novel composite material, comprising ZnO-NP and cellulose-based substrates, offers superior moisture sensitivity, stability, and cost-effectiveness compared to conventional sensing materials. The synthesis process involves the controlled …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 79–85 Read article
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MicroRNAs in Animal Behavior: Regulation of Memory and Decision-Making in Mammals
Abstract: MicroRNAs are small, non-coding RNA molecules that play a crucial role in post-transcriptional regulation of gene expression. In recent years, their significance has extended beyond cellular development and disease regulation, as emerging evidence suggests they are critical mediators in complex behavioral processes, including learning, memory, and decision-making. This article explores the role of miRNAs in regulating neural plasticity and cognitive functions in mammals, emphasizing their involvement in memory formation and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 21–25 Read article