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245 articles for “sequencing”
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Cutting-edge Deep Learning Methods for Predicting and Detecting Cardiovascular Diseases
Abstract: Cardiovascular diseases (CVDs) remain a major global health issue, highlighting the need for improved early detection and risk assessment methods. This research investigates the efficacy of both deep learning and traditional machine learning methods in forecasting cardiovascular diseases (CVDs). We evaluate a variety of models, including Convolutional Neural Networks (CNNs), Recurrent Neural Networks (RNNs), Multilayer Perceptrons (MLPs), Long Short-Term Memory (LSTM) networks, as well as Logistic Regression (LR), Decision Trees …
Published in Recent Trends in Parallel Computing · Vol. 11, Issue 2, 2024 · pp. 36–42 Read article
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Association of Vitamin D Binding Protein BP rs2282679 Gene Polymorphism and Serum Levels of Vitamin D in Patients with Vitiligo
Abstract: For vitamin D to have an impact, the vitamin D receptor (VDR) must be expressed and activated in the nucleus. The VDR has several known genetic variants. Biological impacts can be caused by changes in DNA sequences known as "polymorphisms" that are common in the population. Vitiligo is a disease that causes loss of skin color in patches, and it is a chronic (long-lasting) autoimmune disorder loss of color. The …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 45–52 Read article
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A Review Paper on Lean Manufacturing Implementation Techniques
Abstract: Lean manufacturing was initially designed to reduce waste and maximise resource usage. Later, lean wasdeveloped in response to the competitive and ever-changing business environment. Organizations are compelled to deal with difficulties and complications because of the business environment's rapid change. The ability of any business, whether manufacturing- or service-focused, to consistently and methodically adapt to these changes in order to increase the value of its products may ultimately determine whether …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 2, 2024 · pp. 1–9 Read article
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Lip Reading: Transforming Speech to Text
Abstract: Lip reading, the ability to interpret spoken language by observing lip movements, is a valuable skill that can aid in various applications, particularly in enhancing speech recognition systems. This project explores the implementation of a deep learning-based lip-reading model to improve the accuracy and robustness of speech recognition in challenging environments, such as noisy or audio-limited settings. The proposed lip-reading system leverages Convolutional Neural Networks (CNNs) and Recurrent Neural Networks …
Published in Current Trends in Signal Processing · Vol. 14, Issue 1, 2024 · pp. 23–33 Read article
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In-silico Approach of Few Selected Phytoconstituents on Newer Cancer Targets
Abstract: Background: Cancer’s high death rates are mainly due to, drug resistance and unmet medical demands. It necessitates novel anticancer medications. AI tools aid in efficient and faster drug discovery by analyzing data, modeling processes and optimizing pipeline stages. Aim: The aim of this present study is to evaluate phytoconstituents against novel and newer cancer targets. Methodology: The ligands Daidzein, Resveratrol and Genistein were targeted against the Glutamate dehydrogenase (PDB ID …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 12–17 Read article
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Integrating Deep Learning and Computer Vision for Recognizing American Sign Language
Abstract: The only way the hearing-impaired community can exchange ideas is by utilizing non-verbal communication. The main challenge, however, is that the non-impaired community, which may not comprehend non-verbal communication, would struggle to communicate effectively with this group, and vice versa. The project is purposely devised to admit unwilling and dumb societies to transport ideas and connect with the organization. It aims to bridge the gap between the hearing- and speech-impaired …
Published in Current Trends in Information Technology · Vol. 14, Issue 3, 2024 · pp. 10–17 Read article
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Gene Annotation of Cancer Vaccine for Homo sapiens
Abstract: Objectives: Gene annotation helps us to deduce the structural and functional aspects of a gene that encodes for a functional protein in our body. Thus, by determining the coding sequence and gene location we can derive meaningful insights as to what these genes do in our body. In this study, an unknown gene, cancer vaccine for Homo sapiens has been studied and annotated. Methods: This study was based on a …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 1–14 Read article
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Automated Guided Robotic Armed Vehicle (AGRAV)
Abstract: An automated guided vehicle (AGV) with a robotic arm mounted on top is the subject of this paper's prototype. "How to improve material handling in industries while reducing repetitive work and human involvement in pick and place applications" was the issue statement that was kept in mind. The fundamental issue in industries and warehouses where people work to choose and move goods is that their workdays are constrained by human …
Published in Journal of Control & Instrumentation · Vol. 15, Issue 3, 2024 · pp. 9–18 Read article
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Glitches in the Implementation of Bioinformatics in Medical Settings: A Comprehensive Review
Abstract: Bioinformatics is a dynamic field at the intersection of biology, computer science, and information technology, offering new possibilities in medicine by enabling a deeper understanding of genomics, molecular biology, and personalized treatment approaches. Its integration into healthcare could greatly enhance diagnostics, enable tailored treatments for individuals, and facilitate the analysis of large biological datasets. However, despite its potential, several barriers impede its successful implementation in clinical settings. These include technical …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Risk Assessment of Nitration Process Using HAZOP and Fault Tree
Abstract: The present study addresses the safety issues associated with the nitration reactions. Since the nitration reaction is highly exothermic in nature exhibiting intense heat during the operation and may explode if wrongly handled, the risk assessment of nitration reaction is absolutely necessary. In the present work, the production of Ortho Nitro Chloro Benzene (ONCB) and Para Nitro Chloro Benzene (PNCB) is considered to perform the risk assessment of the nitration …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 3, 2024 · pp. 18–23 Read article
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Advancing EEG Technology for Affordable and Effective Epilepsy Detection
Abstract: For a proper diagnosis and prompt treatment, epilepsy, a neurological condition marked by recurring seizures, needs to be continuously monitored. Manual interpretation is frequently used in traditional approaches for identifying epileptic seizures from electroencephalogram (EEG) signals, which can be laborious and error-prone. In this research, a novel method for automatically detecting epilepsy from EEG data using deep learning algorithms is presented. According to centers for disease control and prevention (CDC) …
Published in Trends in Opto-electro & Optical Communication · Vol. 14, Issue 3, 2024 · pp. 11–18 Read article
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Environmental Pollutants and Biodiversity Loss: Analyzing the Role of Persistent Organic Pollutants in Ecosystem Decline
Abstract: Persistent Organic Pollutants (POPs) significantly impact biodiversity, with various factors influencing their effects on species and ecosystems. Species in poor body condition, like carnivores and predators, are more vulnerable to POPs due to weakened immune systems and reduced detoxification abilities. Dietary habits also affect the accumulation of POPs, as chemicals biomagnify up the food chain. Carnivores accumulate higher concentrations, leading to reproductive failures, hormonal imbalances, and death, while herbivores face …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 9–20 Read article
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An Overview of New Coastal Research Vessel (N-CRV) Dry Dock and Construction
Abstract: A New Coastal Research Vessel (N-CRV) is a specialized ship designed for scientific research in fields like oceanography, geology, biology, and atmospheric studies, equipped with specific facilities and accommodations for sea missions. This paper discusses the coastal research ship dry-dock, construction, and design process, which involves three stages: concept, preliminary, and contract design. N-CRV must utilize scientific cruise, Exclusive Economic Zone (EEZ) survey, deployment, data collection, and seawater sample collection …
Published in Journal of Offshore Structure and Technology · Vol. 11, Issue 3, 2024 · pp. 1–11 Read article
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Study of Strength of Composite Laminates with Ply- Discontinuities Using FEM
Abstract: Present research work attempts to understand the effect of ply-discontinuities on the strength of the FRP Composite. Finite Element Analyses have been performed for specimen undergoing four-point bend loading condition using ABAQUS software. Three specimens consisting of different ply sequences, same resin pocket size and location have been considered for the present analysis. Cohesive zone modelling technique is implemented to simulate and predict crack propagation pattern during failure of composite …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 89–98 Read article
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Data Integration and Visualization in Bioinformatics: Techniques and Challenges
Abstract: Data integration and visualization play essential roles in bioinformatics, facilitating the thorough analysis, and interpretation of intricate biological datasets. In the field of bioinformatics, vast amounts of data are generated from various experimental platforms, such as genomic sequencing, proteomics, transcriptomics, and metabolomics. However, the heterogeneity of these datasets, coupled with their large scale and complexity, presents significant challenges in terms of integration, analysis, and visualization. Data integration techniques aim to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 1–8 Read article
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Advancing IoT Connectivity through Very Large-Scale Integration of Semiconductor Technology
Abstract: The term "integrated circuit" as it is currently used typically refers to a monolithic IC, which is significantly different from an HIC in that the former is created by joining several components on a substrate, while the latter is created in a sequence of steps using a single wafer that is subsequently divided into chips. Hybrid chips are perfect for complicated applications in sectors like artificial intelligence (AI), the Internet …
Published in Journal of Semiconductor Devices and Circuits · Vol. 11, Issue 3, 2024 · pp. 54–63 Read article
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Comparative Efficacy of Hybrid Capture 2 and Real-Time PCR in Detecting High-Risk HPV Genotypes for Cervical Cancer Screening
Abstract: Human papillomavirus (HPV) infection is a leading cause of cervical cancer, making early detection critical for effective prevention and treatment. Among the diagnostic methods available, Hybrid Capture 2 (HC2) and Real-Time Polymerase Chain Reaction (PCR) are widely used for detecting high-risk HPV genotypes, particularly HPV 16 and 18, which account for the majority of cervical cancer cases. This review aims to compare the efficacy of HC2 and Real-Time PCR in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 13–17 Read article
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Exploring the Bourne Again Shell (Bash)
Abstract: The Bourne Again Shell (Bash) is a popular command-line interpreter and scripting language, created as a free software alternative to the original Bourne Shell (sh). Developed as part of the GNU Project, Bash extends the functionality of its predecessor by incorporating features from the C Shell (csh) and KornShell (ksh), making it more versatile and powerful. Bash offers robust command-line editing, job control, and support for functions and variables, enabling …
Published in Journal of Advances in Shell Programming · Vol. 12, Issue 1, 2025 · pp. 01–09 Read article
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The Relationship Between LOH Severity and Androgen Receptor Gene CAG Repeat Length of Korean Men Affected with LOH
Abstract: Context: There have been no investigations on the severity of late-onset hypogonadism (LOH) of Korean male according to their androgen receptor gene CAG repeat length. Aim: To investigate the relationship between late-onset hypogonadism (LOH) and androgen receptor gene CAG repeat length in Korean men. A total of 106 patients with LOH from Pyongyang City participated in this study. LOH was diagnosed in individuals who had a serum testosterone level below …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 32–37 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article