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1074 articles for “PHA”
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Accelerating Drug Discovery with AI: Transforming the Pharmaceutical Pipeline
Abstract: The revolutionary potential of artificial intelligence (AI) is examined in this essay the pharmaceutical industry, highlighting its application across the drug development lifecycle. Artificial Intelligence, specifically via deep learning models and machine learning (ML) such as GANs, RNNs, and transformers, enhances drug discovery, formulation, toxicity prediction, and clinical trials. It streamlines processes like identification of targets, virtual screening, modelling of structure-activity relationships, and medication repurposing. AI is also employed in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 77–84 Read article
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Pharmaceutical Bead Formulations: A Comprehensive Overview into Advanced Drug Delivery
Abstract: Pharmaceutical beads are a unique and flexible drug delivery vehicle that provides numerous possibilities to control the release of drugs, protect them, and increase their therapeutic performance. These beads make it possible to design several types of therapeutic regimens by incorporating active pharmaceutical ingredients in a polymeric or lipid matrix. This review discusses the bead technology in drug delivery from its inception to its present application, focusing on the most …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 78–100 Read article
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Polymer–Gel Composite Phase Change Materials: A Functional Polymer Composite Approach for Solar-Thermal Energy Storage in Building Facades
Abstract: This study investigates polymer–composite phase change materials (PCMs) in the form of polymer–gel hybrids as multifunctional systems for solar–thermal energy storage in building façades. Paraffin- and PEG-based PCMs were embedded into polyurethane and acrylic gel matrices to create shape-stabilized polymer–composites with high PCM loading (70–80 wt%). Differential Scanning Calorimetry (DSC) confirmed distinct melting/freezing transitions at ~56°C (paraffin) and ~42°C (PEG), with enthalpy values of 120–150 J/g, closely matching theoretical predictions, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 36–51 Read article
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Understanding Market Research and Marketing Intelligence in Pharmaceutical Marketing: Role played by Medical Affairs
Abstract: Market Research and Marketing Intelligence are crucial components in pharmaceutical marketing, providing insights that drive strategic decisions and competitive advantage. Market research in the pharmaceutical industry involves collecting and analyzing data to understand market demands, patient preferences, and the competitive landscape. Understanding market research and marketing intelligence in pharmaceutical marketing is very important and medical affairs play a key role by serving as a bridge between scientific knowledge and market …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 124–129 Read article
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A Review of Telepharmacy: Advancements, Challenges, and Future Directions
Abstract: Like telemedicine, telepharmacy is a relatively new term that describes the delivery of pharmacological services. While tele comes from the Greek word “Telos,” which means from a distance, medicine comes from the Latin word “Meden,” which means to heal. The National Association of Boards of Pharmacy defines telepharmacy as the use of information and communication technology to provide patients with pharmaceutical treatment from a distance. Clinical pharmacy services are provided …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 34–42 Read article
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Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, shifting replication domains and reshaping mutational patterns critical for cancer evolution (1,5). DNA replication timing (RT) domains serve as dynamic epigenetic organizers, partitioning the genome into early- and late-replicating regions that correlate with chromatin states, gene …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Barg-e-Tulsi (Ocimum sanctum Linn.) in Unani Medicine: Bridging Classical Therapeutics with Contemporary Pharmacological Evidence
Abstract: In the Unani System of Medicine (USM), Barg-e-Tulsi (Ocimum sanctum Linn.), commonly known as Tulsi or Holy Basil, is a highly valued medicinal herb that has been extensively used for centuries in the prevention and treatment of various ailments. It occupies an important place in traditional Unani therapeutics due to its broad spectrum of medicinal properties and its effectiveness in managing respiratory, gastrointestinal, neurological, and infectious disorders. Classical Unani scholars …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Yield Loss Assessment in Common Bean (Phaseolus vulgaris L.) due to Ascochyta Blight (Phoma exigua var. diversispora (Bubak) Boerema) Disease
Abstract: Ascochyta blight (Phoma exigua var. diversispora (Bubak) Boerema) causes a severe, rapidly developing disease on common beans (Phaseolus vulgaris L.) that can bring about complete plant defoliation and extensive yield loss. Studies were conducted in Rwanda to quantify the yield loss attributed to bean ascochyta blight on 64 common bean genotypes including bush and climbing. Using a split plot design, trials were conducted at three locations, where ascochyta disease is …
Published in Research & Reviews : Journal of Agricultural Science and Technology Read article
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Experimental Analysis Of Thermal Behaviour Of Phase Change Materials In Cooling Applications Of Roof Top Building Slabs
Abstract: In this research article, different phase change materials are incorporated inside the slabs to reduce the heat transfer from the roof. Experiments are conducted during summer season March 2021 to the time lag decrement factor and heat flux to that of results are compared with RCC slab to that of Green material I (CaCl26H2O) and Green Roof with Green material II (48%CaCl2+4.3%NaCl+0.4%KCl+47.3%H2O). On comparison Green Slab II is having better …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 102–114 Read article
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Experimental Investigation on Thermal Conductivity and Viscosity of Phase Change Material (NaNOᴣ and KNOᴣ) with Different Concentrations of ZnO Polymer Nanofluids for Solar Energy Absorption
Abstract: When evaluating the effectiveness of solar heat absorption methods or solar thermal energy storage systems (TESS), heat transfer fluid is a crucial element. Thermal conductivity and usable heat obtained for any industrial or immediate power plant efficiency are improved by the distinctive refining of Heat Transfer Fluid (HFT). The phase change material used in this study, known as solar salt is a blend of 60% NaNO3 and 40% KNO3. It …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 25–35 Read article
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Phase Transformation of Manganese Steel: A Role of Alloying Elements
Abstract: Low alloyed steels that are both strong and ductile are the primary focus of new material concept work due to economic considerations. One key to making good use of these materials is applying the right heat and thermo mechanical treatments. Phase transitions can be influenced by using different alloying procedures. Microstructural evolution and mechanical characteristics were investigated in relation to varying manganese, silicon, and chromium levels. Developing high-strength flat rolled …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 15–20 Read article
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Single-Phase Electric Vehicle Battery Charger With Bidirectional Capability
Abstract: Electric vehicle (EV) technology has become prominent nowadays in the automotive industry and is playing a key role in decreasing greenhouse gas (GHG) emissions and advancing sustainable transportation. Bidirectional battery chargers are a key part of EV infrastructure. They not only help to exchange power from the grid to your car’s battery, but they also let energy flow from your car to the grid, giving you V2G capabilities. EVs may …
Published in International Journal of Optical Innovations & Research · Vol. 2, Issue 2, 2024 · pp. 1–8 Read article
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Marine-Derived Pharmaceuticals: Unlocking the Ocean's Potential for Human Health
Abstract: The ocean, covering 70% of the Earth’s surface, is a rich source of unique bioactive compounds with potential therapeutic applications. This review aims to highlight the significance of marine-derived pharmaceuticals in human health, focusing on clinically approved and commercially available medications. The review covers various marine-derived compounds, their structural features, modes of action, and applications in treating diseases, such as cancer, diabetes, and neurodegenerative disorders. The review identifies several marine-derived …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 1–12 Read article
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Calotropis: A Comprehensive Review of Its Phytochemistry, Pharmacology, and Therapeutic Potential
Abstract: Calotropis gigantea is a genus in the family Apocynaceae that grows in tropical and semitropical climates. India is home to this plant’s distribution. In Hindi, it is referred to as sweta arka. It is well known for its medicinal and ethnobotanical values. Calotropis gigantea, in particular, has a history of use in the treatment of many health-related issues, including disorders of the respiratory system, inflammation, and skin infections. Calotropis gigantea …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 6–20 Read article
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Analytical Technique Optimization and ICH-Directed Verification of a Reverse Phase HPLC Approach for Quantification of Bupropion Hydrochloride
Abstract: This method was developed for retention time, peak resolution and baseline response using Bupropion Hydrochloride under optimized conditions as validation. The method resulted in two well separated, well defined peaks, a minor peak at 7.5 minutes 12 mV and a main peak at 11.52 minutes 150 mV. At the same time, the baseline has remained stable during the chromatographic run and the fluctuations of noise are very small (0.5 ± …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 47–54 Read article
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Metals and Minerals in Pharmacy: Current Trends, Biomedical Applications, and Future Innovations
Abstract: Metals and minerals have played important roles in medicine for centuries, ranging from the use of simple mineral powders in traditional therapies to the development of modern metal-based drugs and nanomaterials. In recent years, advancements in material science, nanotechnology and pharmaceutical engineering have expanded the biomedical relevance of inorganic materials far beyond their conventional use as excipients. This review highlights the growing integration of metallic and mineral systems into pharmaceutical …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 12–24 Read article
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Plant-Derived Psychotropic Agents Targeting Neurotransmitter Systems: Pharmacognostic Evidence, Mechanisms, and Clinical Relevance
Abstract: Psychiatric health problems are also a large burden on global health and existing psychotropic drugs may be restricted by relative effectiveness, side effects, and inadequate long-term tolerability. Plant- based psychotropic agents have subsequently been the focus of interest in the form of complementary or alternative therapies. This review outlines the pharmacognostic, mechanisms of action and therapeutic importance of plant-based psychotropic agents against central neurotransmitter systems. The traditional medicinal practices give …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 34–42 Read article
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Nanoparticle and Lipid-Based Vaccine Delivery Systems: A Systematic Review of Platforms, Stability, Pharmacokinetics, and Immune Modulation
Abstract: The rapid evolution of vaccine technologies over the past decade has highlighted the transformative role of nanoparticle (NP) and lipid-based delivery systems in modern immunization practices. These platforms – including polymeric nanoparticles, lipid nanoparticles (LNPs), liposomes, nanoemulsions, and solid lipid nanoparticles (SLNs) – enable enhanced antigen stability, improved cellular uptake, targeted antigen delivery, and potent immune activation. This systematic review critically examines the physicochemical foundations, manufacturing approaches, stability challenges, pharmacokinetic …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 18–36 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Pharmaceutical Excipient from Agriculture Waste Product
Abstract: Agriculture produces a large Amount of waste, which contain a high amount of cellulose line polysaccharide that form a large part of the plant solid cell wall. This waste product can be use efficiently by a variety of recycling method such as energy source, source of large compound such as cellulose, gum polymers etc. disposal of waste from fruit bearing industry has been problem due to the high cost travel …
Published in Research and Reviews: A Journal of Toxicology Read article