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Research & Reviews: A Journal of Pharmacognosy Review Article

Marine-Derived Pharmaceuticals: Unlocking the Ocean's Potential for Human Health

  1. Bhupendra M. Mahale Pharmaceutical Quality Assurance, P.S.G.V.P.mandals Collage of pharmacy, Shahada
  2. Akshata M. Girase Pharmaceutical Quality Assurance, P.S.G.V.P.mandals Collage of pharmacy, Shahada
  3. Sandip. A. Tadavi Department of Pharmaceutics, P.S.G.V.P.mandals Collage of pharmacy, Shahada
  4. Javesh. K. Patil Department of Pharmacognosy, P.S.G.V.P.mandals Collage of pharmacy, Shahada
  5. Amitkumar R.Dhankani Department of Pharmaceutical Quality Assurance, P.S.G.V.P.mandals Collage of pharmacy, Shahada

Abstract

The ocean, covering 70% of the Earth’s surface, is a rich source of unique bioactive compounds with potential therapeutic applications. This review aims to highlight the significance of marine-derived pharmaceuticals in human health, focusing on clinically approved and commercially available medications. The review covers various marine-derived compounds, their structural features, modes of action, and applications in treating diseases, such as cancer, diabetes, and neurodegenerative disorders. The review identifies several marine-derived medications, including, cytarabine (ara-C) for leukemia and lymphoma, vidarabine (ara-A) for viral infections, ziconotide for pain management, trabectedin for cancer treatment, eribulin mesylate for breast cancer. Additionally, the review discusses the potential of marine-derived compounds in managing diabetes and neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.

Keywords

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