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389 articles for “Bio-agents”
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Indigenous Technique of Biochar Production and Effect of Biochar Application on the Geotechnical Properties of the Expansive Soils
Abstract: Expansive soils have been a source of risk to human beings as they causes huge economic loss including damage to buildings, roads and other civil infrastructures because of their low compressive strength and excessive settlement characteristics. One of the available options is to replace such soils before starting any civil engineering construction but looking to huge costs involved in replacement; it is generally not practiced nowadays. Another viable alternative is …
Published in Journal of Geotechnical Engineering · Vol. 8, Issue 1, 2021 · pp. 50–63 Read article
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Design, Synthesis, and in vitro Evaluation of Novel Benz/Imidazole-2-acetonitrile Derivatives as Antibacterial and Antifungal Agents
Abstract: Benzimidazole is a pharmaceutically important compound. In this research, we were able to prepare several heterocyclic derivatives from it by first preparing a new azo derivative ZH through a reaction of 3-aminoacetophenone with benzimidazole-2-acetonitrile. This azo derivative was then introduced via a condensation reaction with aromatic amine derivatives, resulting in the preparation of two Schiff base derivatives Z1 and Z2. From these bases, six and seven membered heterocyclic derivatives were …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 53–87 Read article
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Synthesis and Characterization of Silver Nanoparticles by using Aqueous Leaf Extract of Tecomella Undulata (SM.) seem. and their Antibacterial Properties
Abstract: Abstract The efficient protocol for bio-synthesis of silver nanoparticles (AgNPs) using Tecomella undulata leaves was developed. The present study revealed that bio-active compounds and secondary metabolites present in the aqueous extract function as stabilizing agent for AgNPs. UV-Visible spectro-analysis and FTIR confirm the presence of bioactive compounds and TEM, EDX and XRD studies confirm the crystalline nature, structure and surface morphology of silver nanoparticles produced from the plant Tecomella undulata. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 2, 2020 · pp. 5–13 Read article
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Quantitative Structure Activity Relationship Studies of Some New 4-Thiazolidinone Derivatives as Antimicrobial Agents
Abstract: In the present study, quantitative structure activity relationship (QSAR) studies have beenperformed on series of 24 compounds of 4-thiazolidinone derivatives with antimicrobialactivity using Chemoffice version 8.0 software. The QSAR models have been developed byusing multiple linear regressions in order to identify descriptors, which are actually focusingtowards the biological activity. Leave one out (LOO) method was employed in crossvalidation analysis to validate the developed model. The best predictive QSAR model derived,had …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 2, 2017 · pp. 1–3 Read article
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3D QSAR Studies of 2,3-Disubstituted Quinazolin Phenyl Acetic Acid Derivatives as Antimicrobial Agents
Abstract: Quantitative structure activity relationship (QSAR) studies have been performed on series of31 compounds of 2,3-disubstituted quinazolin phenyl acetic acid derivatives withantimicrobial activity using Chemoffice version 8.0 software. The QSAR models have beendeveloped by using multiple linear regressions in order to identify descriptors, which areactually focusing towards the biological activity. Leave one out (LOO) method was employedin cross validation analysis to validate the developed model. The best predictive QSAR modelderived, had …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 2, 2017 · pp. 4–7 Read article
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Evaluating the Antibacterial Perspective of Cuminaldehyde, a component of Cuminum cyminum Against Some Common Human Intestinal Pathogens
Abstract: The increasing failures of chemotherapeutics and antibiotic resistance exhibited by pathogenic microbial infectious agents have led to the study on Cuminum cyminum (Family: Apiaceae) for its potential antimicrobial activity against common intestinal pathogens. Cuminaldehyde is considered as the principal component and is believed to be the chief chemical constituent for exhibiting bactericidal activity. The present investigation involved exploration of antibacterial property of cuminaldehyde against some common human intestinal pathogens such …
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 2, 2018 · pp. 10–12 Read article
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A Factualistic Study of Phytomedicinal Activity of Curcuma longa (Haldi): Plant That Infuses Life
Abstract: Curcuma longa, commonly known as turmeric, is a plant of remarkable medicinal significance that has been utilized for centuries in traditional medicine and has garnered considerable attention in modern scientific research. This review explores its extensive phytomedicinal potential, focusing on the plant's bioactive compounds, particularly curcumin, which is recognized as the primary agent responsible for its therapeutic properties. Turmeric contains an array of chemical constituents, including curcuminoids, volatile oils, and …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 14–24 Read article
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Synergistic Procurement and Molecular Characteristics of Full Grain Leather in Advanced Material Engineering
Abstract: This article explores the molecular characteristics and engineering processes involved in the production and application of full-grain leather, recognized for its premium quality due to its intact granular structure. Full-grain leather, undivided into split layers, maintains a robust and durable molecular composition, making it a preferred material in high-quality garment manufacturing. The study emphasizes the role of leather conditioners in restoring the molecular suppleness and moisture retention of leather, crucial …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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Pain Management in Rheumatoid Arthritis: Clinical Role and Therapeutic Implications of NSAIDs
Abstract: Rheumatoid arthritis (RA) is a progressive, chronic autoimmune condition that results in swelling in multiple joints. It is estimated to occur in 0.5–1% of the global population and is more common in women. India has an estimated prevalence of 0.75%. RA causes the destruction of joints and a decrease in disabilities and quality of life. It is accompanied by further manifestations and multiple co-occurring conditions that lead to a greater …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 4, Issue 1, 2026 · pp. 21–27 Read article
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Significance and Applications of Plant Growth Promoting Rhizobacteria (PGPR) In Agriculture: A Review
Abstract: ABSTRACTBacteria that colonize the rhizosphere and plant roots, and enhance plant growth by any mechanism are referred to as Plant Growth-Promoting Rhizobacteria (PGPR). Pathogenic microorganisms affecting crop production is the major and chronic threat to food production and ecosystem stability in global level. As agricultural production intensified over the past few decades, producers became more and more dependent on agrochemicals as a relatively reliable method of crop protection helping with …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 1, Issue 3, 2012 · pp. 9–22 Read article
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Synthesis of Silver Nanoparticles of Cissus Quandrangularis and It’s Virtual Screening Against Gastric Cancer
Abstract: Gastric cancer, also known as stomach cancer, is the third leading cause of cancer-related deaths globally and remains a major health challenge due to its poor prognosis and high mortality, largely attributed to late-stage diagnosis. In this context, plant-based nanomaterials are gaining momentum for targeted therapeutic applications. Cissus quadrangularis, a medicinal plant native to India from the Vitaceae family, is traditionally used for its diverse healing properties. Its stem, in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1551–1569 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 52–58 Read article
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A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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Proper Case Selection to Ensure Judicious Use of Antimicrobial Agents in the Treatment of Periodontal Disease
Abstract: It is now well-known that dental plaque exists as a biofilm, and specific plaque bacteria such as A. actinomycetemcomitans and P. gingivalis are responsible for the initiation and progression of periodontitis. Plaque bacteria within the biofilm are partially protected from antibiotics and host immune reactions. The strategy of periodontal treatment should include a break-up of the biofilm and subsequent elimination of periodontal pathogens. Plaque biofilms cannot be eliminated by daily …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 1, 2016 · pp. 41–53 Read article
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Synthesis and Characterization of Polymer-Based Benzamide Derivatives with Potential Biomedical Applications
Abstract: The present study explores the synthesis and characterization of polymer-supported benzamide derivatives, focusing on their potential biomedical applications. The use of polymer-supported synthesis offers several advantages, including improved reaction efficiency, ease of purification, and reusability of the support material, making it an environmentally friendly and cost-effective approach. The synthesis involved a stepwise reaction sequence, with polymeric supports facilitating controlled functionalization and ensuring high product purity. These materials have been widely …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Role of Nanotechnology in the Diagnosis and Treatment of Waterborne Diseases
Abstract: Nanotechnology provides new aspects for the treatment and diagnosis of diseases using atomic scale engineering of materials. The size of nanoparticles is similar to that of most biological molecules and structures; therefore, nanoparticles can be useful for both in vivo and in vitro biomedical research and applications. At the same time, the unique dimension of nanoparticles empowers them with special capabilities to successfully deliver the drug at the desired site. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 4, Issue 1, 2014 · pp. 19–28 Read article
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Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
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Flavonoids Regulate Airway MUC5AC Mucin Expression through Modulation of Multiple Signalling Pathways
Abstract: Airway mucus is a component of pulmonary innate immune function and plays very important role in defense against invading pathogenic microbes, chemicals and particles. The protective function of airway mucus is attributed to the viscoelasticity of mucins. Mucins are large glycoproteins play important role in cell–cell adhesion, airways protection, Nuclear-factor kappa B signalling, epidermal growth factor receptor signalling. Eleven mucin genes (among twenty identified mucin genes) have been expressed at …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 21–33 Read article
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Screening of Some Triterpenoids Isolated from Terminalia arjuna as Inhibitors of Angiotensin Converting Enzyme to Prevent Cardiovascular Diseases
Abstract: Natural products have been shown to present interesting biological and pharmacological activities and are used as chemotherapeutic agents. Plants have historically been used in treating cardiovascular diseases (CVD) and are recognized for their ability to produce secondary metabolites. Secondary metabolites obtained from different plants have been the starting material for designing different drugs. Many useful phytoconstituents have been isolated from Terminalia arjuna. Tannins and flavonoids are responsible for its anticancer …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 3, 2014 · pp. 12–19 Read article
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How small circuits power big technology in the world of VSIL
Abstract: Very Small Integration Level (VSIL) circuit technology represents an emerging class of ultra- compact, low-power electronic design methodologies that enable the creation of highly efficient and scalable systems. This article explores the fundamental principles behind VSIL circuits, including device miniaturization, optimized layout strategies, adaptive power management, and noise-resilient architectures. We also look into the methodical engineering of VSIL circuits to satisfy the ever-tougher performance, robustness, and long- term energy-efficiency demands …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 2, 2025 · pp. 44–53 Read article