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1046 articles for “regulation”
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Drug Marketing in Tropical Regions and Its Effect on Pharmacovigilance Awareness and Reporting
Abstract: Drug marketing practices in tropical regions present a complex interplay between pharmaceutical promotion, healthcare infrastructure limitations, and public health outcomes. These regions – characterized by high disease burden, socio-economic disparities, and diverse healthcare delivery systems – often experience unique challenges in ensuring safe and rational drug use. Aggressive and sometimes unregulated marketing strategies by pharmaceutical companies may significantly influence prescribing behavior, patient compliance, and, ultimately, pharmacovigilance systems. Pharmacovigilance, defined as …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 · pp. 1–17 Read article
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A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine Analysis
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article
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Erthquake Response of Shear Wall Integrated Step-Back Set-Back Structures on Sloped Ground
Abstract: The study examines how well step-back set-back structures perform seismically when they are resting on a 27° slope in terms of base shear, maximum story displacement, story drift, and time period. Shear walls 200 mm thick are positioned at various points. The seismic performance of the square plan structure having shear wall at corner locations is presented in this study. The study's findings indicate that the shear wall's position affects …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 2, 2024 · pp. 22–31 Read article
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Targeting TNFSF4 in the Management of Systemic Lupus Erythematosus
Abstract: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that remains a significant challenge for both healthcare providers and researchers. Despite advances in understanding its mechanisms, finding effective therapies is still difficult. This review highlights a potential therapeutic target in SLE research: tumor necrosis factor superfamily member 4 (TNFSF4), also referred to as OX40L. We explore how TNFSF4 contributes to SLE development, looking at its role in immune system regulation …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 6–14 Read article
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Exploring the Therapeutic Potential of Phytohormones: Bridging Plant Immunity and Human Health
Abstract: This review highlights the multifaceted roles of phytohormones, including salicylic acid, abscisic acid, cytokinins, and brassinosteroids, emphasizing their contributions to plant immunity and potential therapeutic applications in human health. Phytohormones are critical regulators of plant growth, development, and defense, functioning as signaling molecules that activate and coordinate plant responses to biotic and abiotic stresses. Salicylic acid, in particular, is instrumental in systemic acquired resistance (SAR), a defense mechanism that strengthens …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Isolated Bidirectional Flyback Converter in EV Charging and V2G Systems: A State-of-the-Art-Review
Abstract: The growing adoption of electric vehicles (EVs) and the potential of Vehicle-to-Grid (V2G) technology underscore the importance of efficient and reliable isolated bidirectional DC-DC converters in EV charging systems. The market for electric vehicles (EVs) is expanding at an exponential rate due to the worldwide trend towards sustainable transportation, with electric mobility emerging as a crucial way to lower carbon emissions and rely less on fossil fuels. This review examines …
Published in International Journal of Electrical Power and Machine Systems · Vol. 2, Issue 2, 2024 · pp. 23–32 Read article
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Striking A Balance: Ethical Guidelines for A.I. Integration in Mental Health Services
Abstract: Introduction: Artificial Intelligence (AI) integration in mental health services presents opportunities and challenges. This study examines ethical considerations and proposes guidelines for responsible AI implementation in mental healthcare. The rapid advancement of AI technologies has sparked both excitement and concern within the mental health community, necessitating a thorough examination of their potential benefits and risks. By addressing these ethical considerations, this research aims to contribute to the development of a …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 1, 2025 · pp. 8–15 Read article
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The Clean Water Act: Legal Analysis and Implementation Challenges
Abstract: The Clean Water Act is one of the most far-reaching environmental laws in the United States; it was enacted with express purposes for the protection and restoration of the country's waters. For many years, though, numerous logistical, administrative, and legal challenges have beset its implementation. This paper will undertake a detailed legal review of the CWA, discussing its foundational principles, major amendments, and evolving interpretations by courts. It does so …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 1, 2025 · pp. 1–9 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article
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AI Bias: Causes, Impacts, and Ways to Address It
Abstract: As artificial intelligence (AI) continues to permeate various aspects of society, from healthcare and criminal justice to finance and hiring, concerns over its ethical implications have gained increasing attention. A significant ethical concern is the existence of bias in AI systems. Such biases, often rooted in the prejudices present in training data, can lead to unfair and discriminatory consequences, disproportionately affecting marginalized groups. This paper examines the ethical challenges related …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 1, 2025 · pp. 55–62 Read article
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Potential Risk and Benefits in Developing New Nanobot Technologies and Future Posibilities
Abstract: The development of new nanobot technologies has the potential to revolutionize various fields, including medicine, manufacturing, and environmental science. However, as with any emerging technology, there are potential risks and benefits associated with nanobots. This abstract explores the potential risks, including toxicity, unintended consequences, and environmental impact, as well as the potential benefits, such as targeted drug delivery, diagnostic imaging, and tissue engineering. We also discuss the future possibilities of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 87–93 Read article
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Solar Panel Maintenance and Prevention System
Abstract: Solar energy has emerged as a sustainable and efficient alternative to conventional energy sources. However, maintaining solar panels is crucial to ensure optimal performance and longevity. Accumulation of dust, dirt, and environmental debris can significantly reduce energy efficiency, leading to increased operational costs and potential system failures. To overcome this issue, we suggest an IoT- based Solar Panel Maintenance and Prevention System that facilitates automated cleaning and preventive maintenance via …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 16, Issue 2, 2025 · pp. 29–34 Read article
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Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication
Abstract: Innate immunology represents the body's first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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Optimizing Chromatographic Techniques for Comprehensive Paraben Analysis to Enhance Safety in Consumer Products
Abstract: Parabens (PBs), such as methylparaben (MePB), ethylparaben (EtPB), propylparaben (PrPB), and butylparaben (BuPB), are widely used as preservatives in pharmaceuticals, food, and personal care products due to their antibacterial properties. However, there are growing worries about their potential to disrupt hormonal functions, which has led to stricter regulations. This study focuses on creating a robust high-performance liquid chromatography (HPLC) method for quickly measuring all four parabens in consumer goods. We …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 228–243 Read article
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Revolutionizing Artificial Organs: Next-Generation Membrane Technologies for Precision Medicine and Global Health
Abstract: Membrane technology has emerged as a cornerstone in the advancement of artificial organ systems, offering critical functionalities in selective molecular filtration, tissue scaffolding, and controlled therapeutic delivery. Recent innovations have propelled the field beyond traditional polymeric membranes to include nanostructured, biomimetic, and stimuli-responsive materials, significantly enhancing biocompatibility, selectivity, and durability. The integration of smart technologies, such as AI-driven membrane design, bioelectronic sensors, and personalized fabrication via 3D printing, is ushering …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 29–39 Read article
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Role of Social Media in General Elections 2024 in India
Abstract: The role of social media in the 2024 general elections in India is poised to be a transformative force, significantly impacting political communication, voter engagement, and campaign strategies. With nearly one-third of the electorate having consistent access to social media, this election marks a critical juncture in Indian democracy, reflecting the rapid evolution of digital platforms as vital tools for political outreach and discourse. This shift follows a historical trajectory …
Published in Recent Trends in Social Studies · Vol. 2, Issue 2, 2025 · pp. 50–60 Read article
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AI-Assisted Gain Scheduling for Real-Time Temperature Control in Chemical Reactors
Abstract: Temperature control in continuous stirred-tank reactors (CSTR) represents a critical challenge in chemical process industries due to inherent nonlinearities, time-varying dynamics, and parametric uncertainties. Conventional proportional-integral-derivative (PID) controllers with fixed gains often fail to maintain optimal performance across varying operating conditions, leading to temperature excursions that compromise product quality and safety. This paper presents a novel AI-assisted gain scheduling framework that integrates artificial neural networks (ANN) with adaptive PID control …
Published in Journal of Control & Instrumentation · Vol. 17, Issue 1, 2026 · pp. 24–33 Read article
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Lyapunov-Stable Adaptive Fractional-Order Interval Type-2 Fuzzy Control for Robust Anti-Lock Braking Under Uncertain Road Adhesion Conditions
Abstract: This paper proposes a Lyapunov-stable Adaptive Fractional-Order Interval Type-2 Fuzzy Logic Controller (FO-IT2FLC) for robust anti-lock braking system (ABS) control under nonlinear vehicle dynamics and uncertain road adhesion conditions. The proposed framework integrates fractional-order error dynamics to capture memory-dependent tire–road interaction, interval Type-2 fuzzy inference to model uncertainty via footprint-of-uncertainty representation, and a Lyapunov-based adaptive learning mechanism for real-time parameter tuning. A rigorous stability proof guarantees boundedness of all closed-loop …
Published in Journal of Control & Instrumentation · Vol. 17, Issue 2, 2026 Read article
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Digitally Tunable Dual-Phase Polymer–PCM Composites for IoT-Based Adaptive Thermal Management in Smart Buildings
Abstract: This study presents the design and development of digitally tunable dual-phase polymer–phase change material (PCM) composites for advanced thermal management in smart building applications. The composite is based on a hybrid polymer matrix comprising thermoplastic polyurethane (TPU) and a crosslinked polyvinyl alcohol (PVA) gel, reinforced with paraffin microencapsulated PCM and hydrated salt PCM to achieve multi-stage thermal energy storage. The polymer composite architecture enables enhanced structural integrity, high encapsulation efficiency …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 147–157 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article