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196 articles for “patient-specific”
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Thoracolumbar Spine Surgery: Peri-operative Nursing Care Needs and Quality of Life
Abstract: Aim and Objective: To explore the nursing care needs of the patients after thoracolumbar spine surgery during preoperative, post-operative, home care and to assess the quality of life. Design: An exploratory study. Methods: The study was conducted among 50 patients who had undergone thoracolumbar spine surgery in neurosurgery units of tertiary care hospital from July 2018 to September 2020. The nursing needs were assessed by interviewing participants telephonically using an …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 13–23 Read article
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Transforming Hospital Environments: The Role of Sound Detection
Abstract: Hospitals are sanctuaries of healing, yet they are often paradoxically exposed to a pervasive, often underestimated threat: excessive noise. While internal hospital sounds pose their own challenges, the impact of external sounds – traffic, construction, sirens, and urban clamor – can profoundly compromise patient safety, recovery, and overall well-being. This article explores the critical role of advanced sound detection systems in mitigating this external acoustic intrusion, leveraging technology to create …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 4, Issue 1, 2026 · pp. 28–40 Read article
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Revolutionizing Healthcare: AI in Drug Discovery and Pharmacy Practices
Abstract: Artificial intelligence (AI) has emerged as a revolutionary element across numerous sectors, especially in healthcare and pharmacy. AI systems that can execute functions typically necessitating human intelligence, such as learning, problem-solving, and speech recognition, are poised to transform drug discovery, enhance patient care, and reshape pharmacy practices. AI can help discover drugs with predicting interactions with drug destinations, virtual screening, drug reuse, and drugs that accelerate the development of effective …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 94–100 Read article
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IoT Based Pill Dispenser System
Abstract: Real-time data collection and patient database recording have been facilitated by the Internet of Things. One of the most common reasons a treatment plan does not work for a patient is that the drug is not taken at the prescribed time. People 50 years of age and beyond are more likely to suffer from diabetes, high blood pressure, Alzheimer's disease, Parkinson's disease, and other illnesses. For a patient like this, …
Published in Journal of Microelectronics and Solid State Devices · Vol. 11, Issue 1, 2024 · pp. 18–24 Read article
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IoT-based Heart Attack Prediction System Using Machine Learning
Abstract: Heart disease, particularly heart attacks, is one of the leading causes of mortality worldwide. Timely detection and prompt intervention play a vital role in significantly improving the survival rates of individuals at risk of cardiac events. Unfortunately, most traditional healthcare systems are not equipped with mechanisms for continuous, real-time monitoring of patients' cardiovascular health. This limitation makes it extremely difficult for healthcare providers to identify warning signs early enough to …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 2, 2025 · pp. 1–5 Read article
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What Does Location of Abdominal Pain Say, Anatomically and Homoeopathically
Abstract: Background and justification for the study: Every symptom is an indication of bodily derangements which a patient feels when sick. The medical personal has to recognize these derangements only by symptomatic study of the disease without making any hypothetical theories. Therefore, examining symptoms is the sole correct method for determining the presentation of a disease. In Homoeopathy, a complete symptom is that which covers location, sensation, modalities and concomitant symptoms. …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2024 · pp. 14–19 Read article
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A Study to Develop a Planned Teaching Programme and Demonstration on Intravenous Cannulization for Staff Nurses and Assess Its Effectiveness in Terms of Gaining Knowledge and Practice at Selected Hospital in Delhi, India
Abstract: Introduction: Intravenous cannulization is a fundamental skill for staff nurses, crucial for effective patient care and treatment delivery. Despite its importance, variations in technique and knowledge gaps can impact patient outcomes and safety. This study addresses this need by developing a structured educational program specifically designed to improve the knowledge and practical skills of nursing staff in intravenous cannulization. Objectives of the study were: a) To assess the knowledge of …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 2, 2025 · pp. 35–41 Read article
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Development of a Polymeric Detection System for Salivary Annexin-1: A Potential Tool for Point-of-Care Diagnostics in Periodontal Disease
Abstract: Salivary annexin-1, a protein with anti-inflammatory properties, has emerged as a potential biomarker for periodontal disease. However, current detection methods, like ELISA, are often complex and require laboratory settings. This study explores the development of a novel polymeric detection system for the rapid and sensitive identification of salivary annexin-1. This system could leverage the unique properties of polymers to create a point-of-care diagnostic tool for: (1) early detection and monitoring …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 101–110 Read article
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Horizons in Neuralgia Care: Addressing Unmet Needs and Future Prospects
Abstract: Neuralgia refers to intense, sharp, and often chronic pain resulting from damage or irritation to nerves. It is typically characterized by sudden, shooting pain along the course of a nerve, significantly impairing daily functioning and impacting both physical and emotional well-being. Given its intensity and chronic nature, neuralgia presents a complex challenge in clinical management, emphasizing the importance of timely diagnosis and effective intervention to improve patient outcomes. This comprehensive …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Predictive Factors of Long-Term Sobriety: A Post-Discharge Outcome Study in Mangalore, Goa, and Vasai (2019–2023)
Abstract: Relapse following discharge remains a major challenge in addiction recovery, even with structured treatment protocols in rehabilitation centers. This study examines post-discharge outcomes from Kripa Foundation’s rehabilitation centers in Mangalore, Goa, and Vasai over a five-year period (2019–2023). A total of 100 patients were categorized into four behavioural outcome groups: Clean (Sober), Relapsed, R.I.P. (Deceased), and Unknown. The study aimed to identify demographic and behavioural predictors of sustained sobriety post-discharge. …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 29–44 Read article
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Integrative Network Biology Analysis of GSE6011 Uncovers Molecular Signatures in Duchenne Muscular Dystrophy
Abstract: Duchenne muscular dystrophy (DMD) is a rare, severe neuromuscular disorder demonstrated by progressive skeletal muscle deterioration and premature mortality. Despite advances in supportive care, no definitive cure exists, highlighting the need to explore novel molecular targets. The current study aimed to uncover key dysregulated genes and molecular pathways in DMD through a dataset-specific network biology approach. Publicly available microarray data (GSE6011) from DMD quadriceps muscle biopsies of 22 patients and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 36–48 Read article
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Assessing Supportive Care Needs Among Breast Cancer Survivors: A Cross-Sectional Study
Abstract: Breast cancer poses a significant global health challenge and ranks among the primary causes of cancer-related morbidity and mortality worldwide. The objective of this study was to evaluate the supportive care needs of survivors of breast cancer and examine how these needs are related to various background factors. To accomplish this, a cross-sectional study was carried out with 116 breast cancer survivors, selected using a convenient sampling method. Data were …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 39–42 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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Integration of Biomarkers in III and IV CKD Patients for Evaluation of Their Predictive Value for CVD in CKD Patients
Abstract: Background: Chronic kidney disease (CKD) is presently characterized by the presence of proteinuria and/or a diagnosis of renal impairment. The worldwide significance of CKD is underscored by the fact that its prevalence and incidence have doubled over the past three decades. This paper provides an overview of the existing evidence regarding biomarkers in individuals with CVD or CKD, with a particular focus on the emerging biomarkers (i.e., eGFR, sALB, UACR, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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Understanding Tennis Elbow: Causes, Symptoms, and Available Treatments
Abstract: Tennis Elbow, clinically termed lateral epicondylitis, stands as a prevalent musculoskeletal ailment affecting the outer part of the elbow. Despite its name, this condition isn't exclusive to tennis players; it often arises due to repetitive stress or overuse of the forearm muscles and tendons, leading to micro-tears and inflammation at the elbow's lateral epicondyle. The abstract focuses on elucidating the multifaceted aspects of Tennis Elbow, exploring its causes, symptoms, and …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 1–5 Read article
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Periodontitis and Rheumatoid Arthritis
Abstract: This comprehensive review delves into the complex interplay between Periodontitis and Rheumatoid Arthritis, aiming to unravel the underlying mechanisms and shared inflammatory pathways that connect these seemingly distinct conditions. The review examines a wealth of current research, exploring how chronic periodontal inflammation may contribute to the development and progression of RA and vice versa. Furthermore, the review critically evaluates the clinical implications of this interrelation, emphasizing the need for interdisciplinary …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 31–39 Read article
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Bioconjugates and Biohybrid Polymers: Intricate Cellular Integration Methods and Sophisticated Biofunctionalization Techniques for Tailored Properties in Medical Contexts
Abstract: Bioconjugates are made when biological molecules are covalently linked to manufactured polymers. They can be used in many ways for imaging, diagnosis, and specific drug delivery. Getting perfect cellular fusion is very important for how well they work. Biomolecules can be attached to polymer scaffolds in a controlled way using techniques like click chemistry and site-specific conjugation. This makes sure that the molecules connect optimally with their biological targets. Using …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 227–243 Read article
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Role of Epigenetic Mechanisms in Lung Fibrosis: Therapeutic Opportunities and Challenges
Abstract: Lung fibrosis poses a serious risk to one's health since it might result in respiratory failure due to an abnormal accumulation of fibrotic tissue in the lungs. Epigenetic mechanisms, such as histone changes, DNA methylation, and non-coding RNAs, closely control gene expression patterns and cellular processes associated with lung fibrosis. Anomalies in DNA methylation patterns connected to changes in gene expression profiles and disturbances in fibrotic signalling pathways are potential …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 9–20 Read article