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122 articles for “Clinical data analysis”
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Assessing the Impact of Chlorhexidine Mouthwash on Radiation-Induced Oral Mucositis in Head and Neck Cancer Patients: A Pre-Experimental Study
Abstract: Introduction: Cancer poses a major global health threat and is the second leading cause of death worldwide, following cardiovascular diseases, particularly in developed countries. Among cancers, head and neck cancer ranks as the 6th most common, representing about 6% of all cancer diagnoses. One of the frequent side effects of radiotherapy (RT) is mucositis, an inflammation of the mucous membranes. Chlorhexidine, a commonly used antiseptic and disinfectant found in mouthwashes, …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 1–8 Read article
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A Systematic Review on Factors Contributing to Infertility
Abstract: Infertility is a multifactorial reproductive health condition affecting approximately 10–15% of couples worldwide and continues to represent a major clinical and social challenge. Despite substantial advances in assisted reproductive technologies, diagnostic methods, and therapeutic interventions, many couples still face difficulties in achieving pregnancy. The impact of infertility extends beyond physical health, often leading to emotional distress, social pressure, and financial burdens, especially in societies where parenthood is highly valued. Consequently, …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 31–35 Read article
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Graphs and Their Real-Life Applications in Pharmaceutical Research
Abstract: This study provides a comprehensive overview of the role of graphs in pharmacy research, emphasizing their significance as powerful tools for data visualization, interpretation, and communication. In the field of pharmacy, research often generates large volumes of complex data related to drug development, pharmacokinetics, pharmacodynamics, medication safety, and patient outcomes. Graphs serve as an essential medium to translate these data into accessible, interpretable, and actionable insights, supporting evidence-based practice and …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 01–08 Read article
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Exploring Psychotropic Trends of Medication Use in Psychiatric Outpatients: An Observational Study at a Tertiary Care Hospital
Abstract: Background: Psychotropic medications are essential in managing a wide range of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. Prescribing habits in outpatient clinics can differ a lot depending on things like the patient’s age, background, and medical conditions. Aim: This study aims to explore the trends in psychotropic medication use among psychiatric outpatients at a tertiary care hospital, with a focus on understanding prescribing patterns, demographic factors, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 15–23 Read article
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AI-Powered ECG Prediction System for Detecting Cardiovascular Disease
Abstract: The proposed AI-powered CardioSmart Analyzer, an electrocardiogram (ECG) prediction system, presents an innovative and scientifically rigorous approach to the real-time automated analysis of ECG signals for diagnosing various heart conditions. This research focused on building a predictive model to identify cardiovascular diseases (CVD) using ECG data. A dataset comprising 2,840 12-lead ECG recordings was gathered from medical facilities in Gazipur, Bangladesh, over the period from June to August 2024. The …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 51–85 Read article
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A Comprehensive Review of CNN-Based Framework for Multi-Sign Detection of Diabetic Retinopathy in Fundus Images Using Public Datasets
Abstract: Diabetic retinopathy (DR) is one of the main causes of vision impairment. Blindness prevention and effective treatment depend on early detection. A thorough deep learning-based framework for the automatic segmentation and simultaneous detection of exudates, hemorrhages, and microaneurysms – three important DR indicators – from retinal fundus images is presented in this work. These three pathological signs’ corresponding annotated image patches, along with background (no-sign) areas, were used to train …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article
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Comparative Analysis of the Structural Integrity and Dimensional Stability of Additively Manufactured Biopolymers vs. Thermoformed PETG: A 1-Year Retrospective Study on Polymer Performance in Orthodontic Applications
Abstract: Objective: This study aimed to evaluate the long-term dimensional accuracy and structural performance of direct 3D-printed biopolymers compared to conventional vacuum-formed Polyethylene Terephthalate Glycol (PETG) composites. The investigation focused on how different polymer processing methods (additive manufacturing vs. thermoforming) influence material thinning and resistance to occlusal stress. Methods: A retrospective analysis was conducted on 60 cases (n = 60) of post-orthodontic maintenance. The sample was divided into two cohorts: Group …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 140–146 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Efficacy of Educational Intervention on Knowledge Regarding High-Risk Pregnancy and Its Management in Terms of Knowledge Gain Among Antenatal Women
Abstract: Background: High-risk pregnancies are associated with increased maternal and fetal complications and require timely identification and proper management. Many antenatal women have limited knowledge regarding high-risk conditions and the necessary precautions. Structured teaching programs can significantly improve awareness and empower mothers to take proactive steps for safe pregnancy outcomes. Aim: To assess the effectiveness of a structured teaching program on knowledge regarding high-risk pregnancy and its management among antenatal women …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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Pharma Guard: Smart Medication Management System
Abstract: Pharma Guard Smart Medication Management System presenting a comprehensive overview of an innovative technology designed to revolutionize medication management in healthcare settings. In an era of advancing digital solutions, the Pharma Guard system offers a sophisticated approach to ensuring medication safety and adherence. Through the integration of smart technology, including internet of things (IoT) devices and machine learning algorithms, Pharma Guard enables real-time monitoring, tracking, and management of medication consumption …
Published in International Journal of Mobile Computing Technology · Vol. 2, Issue 1, 2024 · pp. 30–37 Read article
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Enhancing Glaucoma Diagnosis with Deep Learning: A Study Using ResNet-50 and DenseNet-121
Abstract: Glaucoma is a leading cause of irreversible blindness worldwide, mainly resulting from progressive optic nerve damage, often related to elevated intraocular pressure. Early detection is essential to prevent vision loss, but traditional diagnostic methods rely on specialized equipment and trained professionals, making large-scale screening difficult. This study uses a publicly available fundus imaging dataset to explore the effectiveness of deep learning models for glaucoma detection. These datasets provide medical images, …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 9–18 Read article
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A Conceptual Framework for AI-Integrated Metabolomics in Predictive Health Systems for Resource-Constrained Environments
Abstract: The increasing prevalence of non-communicable diseases (NCDs) continues to place a significant strain on healthcare systems, particularly in low- and middle-income regions where access to early diagnostic infrastructure is limited. Conventional healthcare approaches remain largely reactive, often detecting diseases at advanced stages when treatment effectiveness is reduced. This challenge underscores the need for predictive, cost-effective, and data-driven healthcare solutions. This study presents a conceptual framework that integrates metabolomics with artificial …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 2, 2026 Read article
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Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article
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Breast Cancer Detection Using Machine Learning: A Comparative Analysis of Supervised Learning Algorithms
Abstract: Globally, breast cancer remains a predominant cause of mortality among women, highlighting the urgent need for timely and precise diagnostic approaches. This research explores the application of machine learning algorithms—including Logistic Regression, SVM, Naïve Bayes, KNN, and Random Forest—on the Wisconsin Breast Cancer Dataset for effective tumor classification. Key pre-processing steps such as missing value handling, feature scaling, and dimensionality reduction were employed to improve model performance. The study evaluated …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 46–52 Read article
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Advances in Multiclass Oral Cancer Detection Using Spectroscopic and AI Techniques
Abstract: Oral cancer, primarily OSCC, is still a major health issue worldwide, especially in low-HDI countries. Early diagnosis is essential since survival rates for early detection are much higher than for late-stage detection. However, traditional methods like visual inspection and biopsy are time-consuming, invasive, and rely on the clinician's skill, which is a limitation in accessibility and efficiency. Oral cancer detection has just been revolutionized by recent advances in spectroscopic techniques, …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 39–48 Read article
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Accelerate Drug Development with Pharmacokinetic Softwares
Abstract: During continuously evolving technologies and mechanized equipments, there has been a tremendous growth in the pharmaceutical sector over the past few decades. New technologies, software, devices, and techniques are being developed or researched upon with each passing day. By leveraging pharmacokinetic software, researchers can efficiently analyze vast datasets from preclinical and clinical studies, extracting actionable insights that inform decision-making early in the development cycle. This predictive capability not only accelerates …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
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Comparative Proteomics: From Cell Lines to Clinical Samples
Abstract: Comparative proteomics is a powerful tool for understanding the molecular differences between various biological samples. It entails identifying and measuring proteins in complex biological samples to assess their abundance, modifications, and interactions under various conditions. This approach plays a crucial role in advancing biomedical research, especially in disease understanding, biomarker discovery, and therapeutic development. While cell lines are widely used for proteomic studies due to their controlled environments and reproducibility, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 30–34 Read article
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A Systematic Review on Leukemia Detection and Classification Techniques Using Gene Expression
Abstract: Early diagnosis of genetic diseases is crucial for effective treatment, especially in the case of Leukemia, a type of blood cancer characterized by abnormal proliferation of white blood cells. This paper presents a systematic review of recent computational techniques for the detection and classification of Leukemia using gene expression data obtained from DNA microarray analysis. The study explores diverse methodologies including machine learning (ML), deep learning (DL), and bio-inspired algorithms …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Copper Sulfide Semiconducting Nanoparticles for Antibacterial Applications: Synthesis Strategies, Mechanisms and Performance – A Review
Abstract: Copper sulfide nanoparticles (CuS NPs) have drawn growing attention as a next-generation antibacterial platform, owing to their tunable structural, optical, and catalytic properties. This review consolidates current evidence on CuS NP synthesis, mechanisms, and antibacterial performance, comparing chemical and green synthesis routes alongside the effects of morphology, doping, and surface modification. Mechanistically, CuS NPs act through several overlapping pathways, including reactive oxygen species generation, bacterial membrane disruption, ion release, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Physicochemical Transitions and Polymerization Dynamics in Multi-Generational Dentin Adhesives: A Critical Review of the Resin-Dentin Composite Interface
Abstract: Adhesive dentistry has undergone a transformative refinement over the past three decades, transitioning from technique-sensitive, multi-step etch-and-rinse protocols to streamlined universal formulations. This narrative review critically synthesizes evidence from thirty peer-reviewed investigations to evaluate the evolution of dentin bonding agents from the fourth through the eighth generations. The analysis places particular emphasis on the physicochemical dynamics of the resin-dentin interface, including interfacial bond strength metrics, marginal integrity, and microleakage behavior. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 209–228 Read article