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1983 articles for “failure-prediction AUROC of 0.967” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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Recovery of Mycelial Biomass of Agaricus Bisporus, Pleurotus Ostreatus, Ganoderma lucidum, Hieracium Erinaceus: A comparative Study
Abstract: Mushrooms are the spore-bearing fruiting body of fungi which has a significant potential for numerous applications like pharmaceuticals, textile industry, bioremediation, soil management, alternative to toxic packaging materials and environment sustainability. Mushrooms generally belongs to the class Basidiomycota or Ascomycota. They are typically made of hyphae, the tiniest threads which comprises most fungi. Mycelia are tiny thread like structure which help in making vegetative part of fungus. In this study, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 12–18 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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Effectiveness of RMC Intervention on Knowledge, Attitude and Practice of Nurses and Maternal Perception
Abstract: A preliminary investigation was undertaken to create and assess the impact of RMC (Respectful Maternity Care) interventions on the knowledge, attitudes, and practices of nurses, as well as maternal perceptions regarding RMC, within maternity units at specific hospitals in Chandigarh. A quasi-experimental research design was utilized for data collection from nurses, while a post-test only design was employed for collecting data from mothers. A preliminary investigation, constituting 10% of the …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 2, 2024 · pp. 26–31 Read article
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Evaluate the Effectiveness of Self Instructional Module on Knowledge Regarding Legal Aspects of Nursing Practice Among Staff Nurses At Selected Hospitals, Hassan District, Karnataka
Abstract: Hassan District Government Hospitals were the sites of the quasi-experimental research. The study’s goal was to compare the pre and post-test scores of the two groups of nurses in charge of the experimental and control conditions, respectively. Create a self-paced learning module covering legal considerations in nursing practice for the control group and have them complete it. Pre- and post-test scores will be compared between the experimental and control groups …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 2, 2024 · pp. 39–48 Read article
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Fabrication and drilling characterization of Hemp & Grewia-Optiva hybrid composite and comparison with ANN model
Abstract: In recent days the use of natural fibers has increased over synthetic fibers due to various advantages. The alkali treatment for these natural fibers further improves the adhesion between fiber and matrix and greatly enhances the mechanical properties of the composite. The present study involves the fabrication of a hybrid composite using the alkali-treated (5% NaOH concentration) natural fibers – Hemp &Grewia-optiva as reinforcement material and epoxy as a matrix …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 138–146 Read article
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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Influence of Gd Doping in Structural, Morphological and Optical Properties of Zno Nanostructures Synthesised Via Sol-Gel Processes
Abstract: In this study, nanocrystalline Zn1-xGdx (x=0.0 and 0.03) samples were synthesised via the Sol-gel combustion process. An array of analytical techniques was employed to examine the prepared samples to determine their different physical features. For both pristine and Gd-doped samples, the crystal symmetry is hexagonal with the P63mc space group which is verified via the Rietveld refinement analysis of X-ray diffraction (XRD) data. The atoms' bond length Zn-O and bond …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 219–225 Read article
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Toxicology-Focused Development and Validation of an RP-HPLC Technique for Quantifying Bempefoic Acid and Rosuvastatin in a Fixed-Dose Combination
Abstract: A straightforward, precise method was developed to simultaneously assess Bempedoic acid and Rosuvastatin in both bulk and tablet forms. Utilizing a DIKMA Spursil C18 column (4.6 mm x 250 mm, 3.0 μm), chromatography was conducted with a mobile phase comprising 30% phosphate buffer and 70% acetonitrile, flowing at 1 ml/min. Operating at ambient temperature, the optimized wavelength for detection was set at 240 nm, revealing retention times of 4.418 min …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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UV Method of Development and Validation of Olaparib
Abstract: An analytical method must be developed and validated in the discovery, development, and production of pharmaceuticals to ensure the identification, purity, potency, and performance of drug commodities. Quality control laboratories use official test protocols that emerge from the processes. A simple ultraviolet spectrophotometric approach was designed and validated using various characteristics, including linearity. Precision, reproducibility, accuracy, robustness, ruggedness, limit of detection, and limit of quantification are among the measuring criteria. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 20–27 Read article
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Targeting Dystrophin Restoration and Neuroprotection in Duchenne Muscular Dystrophy: Insights from Withania somnifera
Abstract: Duchenne muscular dystrophy is a genetic disorder. This disease affects men more common than women. Main objective of the present study was to identify the naturally active phytocompounds from Withania somnifera (Ashwagandha). Ashwagandha has a great value in the field of Ayurveda and Indian medicine and is used for treating muscular and neurological disorders. Toxicity prediction, molecular docking, statistical information, drug illness prediction, and Absorption, distribution, metabolism, excretion, and toxicity …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 64–84 Read article
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Evaluation And Demonstration of MAR1495 And Local Strain (SB-12) on Soybean Yield At Gofa Woreda Southern Nation Nations Nationalities and Peoples of Ethiopia
Abstract: Soybean is the most important legume crop in the world which can be used for human food source, animal feed, soy milk production, oil production as well as for soil fertility improvement by fixation of nitrogen. The benefits apiece use of Rhizobium inoculants show that a completely good deal of services may be saved by borderline labourers by utilizing quality proven inoculants on the farm. Rhizobia immunization to seeds is …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 2, 2024 · pp. 52–59 Read article
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Effect of Valsalva Maneuver Prior to Cannulation on Pain Among Patients Undergoing Peripheral Venous Cannulation
Abstract: Peripheral venous canulation is the common nursing procedure carried out which cause soreness to the recipient. Previous experience of peripheral venous cannulation may result in negligence or delay in need of medical care. Valsalva Maneuver is a non-pharmacological and cost- effective method to decrease intensity of pain during peripheral venous cannulation. Aim: To assess the effect of Valsalva Maneuver prior to cannulation on pain among patients undergoing peripheral venous cannulation. …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 1–6 Read article
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A Study of Environmental Pollution in Some Areas of the City of Najaf for Some Heavy Metals
Abstract: Pollution is one of the most important problems that people face at the present time, and the problem of soil pollution is the most serious, due to its relationship to human health and other organisms. Soil sample collection areas in the city of Najaf were chosen based on several factors, including traffic, industrial and urban activities, and population density. Soil samples were taken at a depth level ranging between 0-15 …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 2, 2024 · pp. 14–23 Read article
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Presence of a Bulk Viscous Universe within f(R, T) Gravity
Abstract: This paper offers a comprehensive analysis of a bulk viscous universe in the context of f(R, T) gravity, where (R) signifies the Ricci scalar and (T) represents the trace of the energy-momentum tensor. The primary objective of our work is to get explicit solutions to the modified field equations by using a power-law scale factor representation. With this method, we have obtained functions of cosmic time and redshift for the …
Published in International Journal of Universe · Vol. 1, Issue 1, 2025 Read article
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Toxicological Optimization and Assessment of Buccal Films Containing Felodipine Co-crystals to Enhance Bioavailability
Abstract: The preformulation study of felodipine was carried out and it was found that the drug is poorly water soluble. The co-crystals were prepared using three different co-formers sorbitol, ascorbic acid and oxalic acid. The solublity enhancement was observed in combination with sorbitol compared to other co-formers used. The characterization of co crystals was performed like PXRD, FTIR, SEM Analysis. XRD results indicates the amorphous form of the drug. The co-crystals …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 10–29 Read article
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Study of Perovskite (CH3NH3PbI3) Solar Cell using CuI (Copper Iodide) as Hole Transport Layer (HTL) at different thickness of HTL layer
Abstract: While solar energy is a viable option, future clean energy solutions may require other energy sources. Renewable electricity sources are known for being affordable, easy to access, and not producing greenhouse gases. Photovoltaic cells, which turn sunlight into electrical power, are a good choice. Over the last twenty years, advancements in photovoltaic technology have lowered costs and improved the efficiency of solar cells. Perovskite materials, recognized for their unique crystal …
Published in Journal of Power Electronics and Power Systems · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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“Evaluation of superoxide Dismutase (SOD) enzyme level and some indicators in people exposed to smoke”
Abstract: The aim of this study is to assess the level of SOD enzyme and its impact in people who are exposed to smoking, in addition to measuring C-interactive protein, and finally measure a complete picture of blood samples taken from patients. The results of the current study showed there is a significant differences (p<0.05) in the activity of the SOD. The mean of SOD activity in patient was 127.9 U/ml …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 52–55 Read article
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Analysis of Perovskite (CH3NH3PbI3) Solar Cells Using Cu2O as a Hole Transport Layer (HTL) with Varying ETL Thickness
Abstract: Solar cells offer a viable option for creating new clean energy solutions, though they may require supplementary energy sources. Renewable electricity sources, known for being affordable, accessible, and greenhouse gas-free, are increasingly popular. Photovoltaic cells, which convert sunlight into electricity, stand out as an excellent choice. Over the past two decades, advancements in photovoltaic technology have significantly reduced costs and enhanced the efficiency of solar cells.[4] Perovskite materials, recognized for …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 38–48 Read article
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A Random Forest Approach to Navigating Cryptocurrency Market Fluctuations
Abstract: This study looks at the main elements influencing daily price variations to improve our analysis and prediction of Bitcoin values. Our forecasting algorithm is based on comprehensive data that we have collected and analyzed over the last few years. Because the Random Forest algorithm provides more accurate forecasts than previous techniques, that is why we chose it. Predicting the price swings of cryptocurrencies, like Bitcoin, can be challenging due to …
Published in Journal of Electronic Design Technology · Vol. 15, Issue 2, 2024 · pp. 7–11 Read article