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81 articles for “antibiotic resistance”
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Development and Fabrication of Biohydrogel for Targeted Delivery of Delafloxacin for Bacterial Skin Infections
Abstract: The escalating challenge of bacterial resistance necessitates innovative drug delivery systems to enhance the efficacy of antibiotics. This study focuses on the development and optimization of a biohydrogel formulation for the targeted delivery of Delafloxacin, aiming to improve its therapeutic outcomes against resistant bacterial strains. Utilizing a 3² factorial design, biohydrogel formulations incorporating Poly(N-isopropylacrylamide) (PNIPAM) and Genipin were synthesized. The optimization process was guided by Design Expert software, focusing on …
Published in Research & Reviews: A Journal of Drug Design & Discovery Read article
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article
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Antibiotic Residues in Broiler Meat: Challenges for Food Safety, Public Health, and Sustainable Broiler Farming Issues
Abstract: Antibiotic residues in broiler meat pose significant risks to food safety, public health, and the sustainability of poultry farming. The use of antibiotics in broiler production, both for therapeutic and prophylactic purposes, has led to the accumulation of residues in meat, which can contribute to the development of antimicrobial resistance (AMR). This paper explores the various potential sources of antibiotic residues in broiler meat, including feed-related factors, water contamination, injection …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 77–90 Read article
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Comparative Evaluation of the Use of LSTR with Double Antibiotic Paste Versus Zinc Oxide Eugenol as Obturating Material in Primary Teeth Pulpectomy
Abstract: The management of infected primary teeth is a vital aspect of pediatric dentistry, with the primary objective being the retention of the tooth in the oral cavity until its natural exfoliation. Preserving the health, structure, and appearance of primary teeth is essential for ensuring the correct eruption and alignment of permanent teeth. Pulpectomy has traditionally been the preferred treatment for primary teeth with irreversible pulp damage. Traditionally, Zinc Oxide Eugenol …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 1–5 Read article
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In-Silico Repurposing of Antipsychotic Drugs Against Novel Protein Targets in Multidrug-Resistant Mycobacterium tuberculosis
Abstract: Multidrug-resistant TB is a growing worldwide health concern, particularly in high-burden areas. Resistance to frontline drugs like isoniazid and rifampicin is caused by mutations in key Mycobacterium tuberculosis proteins. Given the difficulty of developing new antibiotics, medication repurposing offers a good alternative. The potential use of molecular docking to target resistance-associated TB proteins with FDA-approved antipsychotic drugs is investigated in this work. Three proteins were selected: InhA (PDB ID: 5W07), …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 49–63 Read article
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Fabrics and medical devices (catheters) coated with Zn doped CuO nanoparticles kills micro-oganisms and provide healthy environment
Abstract: These days, drug resistance by microorganisms is a major challenge in the field of medicinal chemistry. Most of the familiar antibiotics turnout to be of no impact in curbing the proliferation of microorganism (bacteria, virus and fungus). To address the issue of multi-drug resistance (MDR) and extremely drug resistance (EDR) in microorganisms that cause various health complications, like the dental decay, biofilm formation, foul smell, delayed wound healing, aggravation of …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 1, 2025 · pp. 1–9 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Microorganisms used in aquaculture
Abstract: Microorganisms play a vital role in the health and sustainability of aquaculture systems, contributing to water quality management, disease control, and the overall productivity of aquatic farms. Beneficial microorganisms, including bacteria, fungi, algae, and probiotics, are increasingly recognized for their positive impact on aquaculture operations. These microorganisms can enhance nutrient cycling, promote the breakdown of organic waste, and reduce the need for harmful chemicals, thus improving the environmental footprint of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article
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Phyto Biotics in Aquaculture
Abstract: This paper aims to assess the existing knowledge on the use and effects of phytobiotics in fish farming, as well as their potential for broader application in aquaculture. With the rising demand for fish, there has been a noticeable decline in fish production in recent years, which could be a driving factor behind the increasing interest in using phytobiotics in this field. The main factor contributing to the decrease in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 2, 2024 · pp. 18–22 Read article
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Copper Sulfide Semiconducting Nanoparticles for Antibacterial Applications: Synthesis Strategies, Mechanisms and Performance – A Review
Abstract: Copper sulfide nanoparticles (CuS NPs) have drawn growing attention as a next-generation antibacterial platform, owing to their tunable structural, optical, and catalytic properties. This review consolidates current evidence on CuS NP synthesis, mechanisms, and antibacterial performance, comparing chemical and green synthesis routes alongside the effects of morphology, doping, and surface modification. Mechanistically, CuS NPs act through several overlapping pathways, including reactive oxygen species generation, bacterial membrane disruption, ion release, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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A Review of Biotechnology Advancements as Key Drivers of Scientific Innovations
Abstract: The rising human challenges have necessitated the quest to find lasting solutions to improve living standards. Challenges in food security in terms of quality and quantity, medical and health issues, energy deficiency and limitations in areas of transportation, domestic and industrial needs, as well as environmental issues are some major areas of application of biotechnology to sustain human existence. This review examines major scientific innovations driven by biotechnology. Biotechnology applied …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 22–33 Read article
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Overview of Virulence Factor of Staphylococcus sp.
Abstract: Staphylococcus is a highly virulent genus of bacteria that can cause a range of infections in humans and animals. The production of toxins, enzymes, and biofilms contributes to its ability to establish infections and evade host defenses. Understanding the characteristics and virulence factors of Staphylococcus is crucial for the development of effective prevention strategies and treatment options. Staphylococcus aureus is a significant etiological agent of nosocomial infections on a global …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 25–31 Read article
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Negative Perceptions of Broiler Consumers: Exploring Societal Attitudes, Cultural Ethics, and Health Concerns for Sustainable Production
Abstract: Negative perceptions of broiler chicken remain a significant barrier to its acceptance and market sustainability. This study investigates the societal attitudes, cultural ethics, and health concerns that influence consumer perceptions and challenges the broiler industry. Ethical issues, including animal welfare and perceived unnatural rearing practices, often fuel consumer distrust. Health concerns such as antibiotic residues, growth hormone usage (often misunderstood), and lower nutritional value compared to native breeds further exacerbate …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 2, 2025 · pp. 9–22 Read article
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Trichoderma: beneficial fungus for sustainable agriculture
Abstract: As environmentally beneficial substitutes for chemical pesticides, Trichoderma species are being utilized in agriculture more and more. Disease suppression, increased plant growth, and increased tolerance to environmental stress are just a few advantages they provide. These fungi are used in a wide range of cropping systems and formulations around the world. Their use is growing worldwide, particularly in Asia and Europe. In contemporary crop management, items derived from Trichoderma are …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 25–29 Read article
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Antifungal Susceptibility Pattern of Candida Species Isolates from Dehradun City Hospitals
Abstract: The present investigation on the topic entitled “Antifungal susceptibility analysis of Candida species isolates from Dehradun City hospital.” was accomplished in the Doon University Microbiology laboratory (P.G.) and Hospital, Dehradun, Uttarakhand, during the period of February 2021 to July 2021. A total of 42 clinical samples were collected from patients, suspected of candidiasis from Dehradun city hospitals. Clinical samples were collected from oral cavity, blood, vaginal fluid and urine of …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 Read article
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Comprehensive Strategies for the Prevention and Management of Genital Thrush in Males and Females: A Public Health Approach in Punjab (September 2024 to February 2025)
Abstract: Background: Genital thrush, a common fungal infection caused mainly by Candida albicans, affected both men and women, leading to itching, discomfort, and recurrent infections. In Punjab, high humidity, poor hygiene awareness, excessive antibiotic use, and limited access to healthcare contributed to its widespread occurrence. Without effective prevention and management strategies, the condition significantly impacted quality of life. Addressing this issue through a public health approach was essential for reducing its …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 Read article
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Functional Biomolecules in Animal Nutrition: Biochemical Mechanisms and Their Impacts on Growth Performance and Health Outcomes
Abstract: Functional biomolecules have emerged as critical modulators of animal nutrition, extending beyond conventional nutrient supply to regulate biochemical and physiological processes that determine growth performance and health outcomes. This review synthesizes current knowledge on diverse classes of bioactive compounds, including amino acids, peptides, fatty acids, vitamins, minerals, phytochemicals, and microbial-derived metabolites, and their roles in livestock systems. Emphasis is placed on underlying biochemical mechanisms such as enzyme activation, nutrient signaling …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Ecological, Economic, and Medical Roles of Fungi: Insights from Mycology in Addressing Global Challenges"
Abstract: The large and diverse kingdom of fungi is vital to ecosystems, industry, agriculture, and medicine. Due to its ecological and biotechnological value, mycology has grown in importance. Fungi are crucial to natural systems and human life, decomposing organic materials, developing mutualistic interactions with plants, and producing antibiotics and fermented products. Recent advancements in molecular biology and genomics have significantly enhanced our understanding of fungal diversity, physiology, and evolutionary processes. These …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article