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747 articles for “Targets”
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Fungi in the Global Bioeconomy: Harnessing the R Potential Across Agriculture, Medicine, Industry, and Environmental Sustainability
Abstract: One of the most diverse and functionally versatile groups of living organisms, fungi has played a significant role in maintaining ecological balance, human well-being, agricultural production, and industrial processes. Despite their vast potential, the use of fungi systems in solving some of the most serious challenges facing the world today, such as climate change, food security, and AMR, is still in its infancy. New developments in genomics, biotechnology, and systems …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 20–27 Read article
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In Silico Identification of Therapeutic Agents for Dengue Virus by Molecular Docking
Abstract: The dengue virus causes serious health issues and a loss of quality of life. Dengue poses a yearly threat to half of the world’s population. The drugs that are based on allopathy are expensive and also exhibit toxic effects on tissues and biological activities. It is also generally accepted that most pharmacologically active drugs, including those derived from medicinal plants, are isolated from natural sources. The present study is directed …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 01–14 Read article
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Exploring the Intersection of AI Network Pharmacology and Ayurveda: Innovations in Traditional Medicine
Abstract: Integrative frameworks that integrate traditional medicine and modern computer research are increasingly important for advancing evidence-based, individualized healthcare. One interesting strategy is the combination of Ayurveda, network pharmacology, and artificial intelligence (AI). AI expands the capability by allowing for the quick analysis of biomedical big data, the identification of therapeutic trends, and the optimization of treatment plans. Ayurveda, with its long-standing emphasis on individualized care, holistic balance, and natural remedies, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 92–98 Read article
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A Study to Assess the Knowledge Regarding Pradhan Mantri Jan Arogya Yojana (PM-JAY) Among the General Public in a Tertiary Care Teaching Hospital, Kuppam
Abstract: Background: Ayushman Bharat, the flagship scheme of the Government of India, was launched to achieve Universal Health Coverage (UHC) as per the National Health Policy 2017. It aims to address healthcare needs comprehensively by transitioning from fragmented approaches toward a holistic system. Pradhan Mantri Jan Arogya Yojana (PM-JAY) is a pivotal component of this scheme, striving to achieve UHC by providing comprehensive healthcare services to underprivileged families. Assessing public awareness …
Published in International Journal of Community Health Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 1–6 Read article
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Optimization of Pesticide Requirement Calculations for IoT-Operated Hexacopter Delivery Systems
Abstract: The integration of Internet of Things (IoT) technology into precision agriculture has transformed pesticide application strategies, enabling resource-efficient and environmentally sustainable practices. This study presents a computational methodology for optimizing pesticide requirements in an IoT-operated hexacopter system, designed for dynamic, data-driven pesticide delivery. Leveraging a fusion of real-time telemetric data from onboard LiDAR, multispectral imaging sensors, and environmental monitoring modules, the system employs predictive analytics and edge computing to calculate …
Published in International Journal on Drones · Vol. 2, Issue 1, 2026 · pp. 08–14 Read article
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Nano-Chemical Revolution in Vaccinology: A Study
Abstract: The development of traditional vaccines, reliant on attenuated pathogens or purified proteins, has historically been limited by slow development timelines, poor stability, and low immunogenicity requiring potent, often non-specific, adjuvants. This synthesis argues that the convergence of nano-material science and meticulous chemical engineering represents the next major paradigm shift in preventative medicine. Nano-materials, particularly Lipid Nanoparticles (LNPs) and various polymeric or inorganic scaffolds, have transitioned from theoretical constructs to essential …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 Read article
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Biomechanical Impact of Text Neck Syndrome on Cervical Spine and Upper Quarter Musculoskeletal System
Abstract: Text Neck Syndrome (TNS) has emerged as a modern musculoskeletal disorder associated with prolonged use of handheld digital devices, resulting in sustained cervical flexion and altered spinal biomechanics. This article explores the biomechanical consequences of TNS on the cervical spine and upper quarter musculoskeletal system, including muscular imbalance, altered load distribution, ligamentous strain, and degenerative changes. Increased cervical flexion significantly elevates compressive forces on intervertebral discs and facet joints, disrupting …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 Read article
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Nitrosamine Accumulation, Processing Variables, and Indigenous Plant Inhibitors in Nigerian Traditionally Processed Meats
Abstract: N-nitrosamines are classified as probable or possible human carcinogens by the International Agency for Research on Cancer. Carcinogenic N-nitrosamines — principally N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) — are formed in abundance during the preparation of widely consumed Nigerian traditional processed meats including suya, kilishi, and balangu. This original investigation combined a six geopolitical zone of Nigerian market survey with laboratory-controlled model system experiments, effects of processing parameters on N-Nitrosamine formation …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 61–72 Read article
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Challenges And Constraints Affecting Female-Owned Rural Farm Businesses in Plateau State, Nigeria
Abstract: This study examined the challenges and constraints affecting female-owned rural farm businesses in Plateau State, Nigeria. No prior study had conducted a comprehensive, quantitative, state-wide investigation covering all 17 local government areas (LGAs) of the state, and this study addressed that gap. The objectives were to identify the challenges faced by female-owned rural farm businesses, assess their relationship with business performance, and determine how strongly these challenges predicted performance outcomes. …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 1–13 Read article
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Nature’s Pharmacy: Plant-Based Antifungal Agents and Their Therapeutic Potential
Abstract: Antifungal resistance has increased dramatically over the last 10 years, causing serious problems for healthcare because of higher morbidity and death. The urgent need for new treatments is highlighted by the scarcity of effective antifungal medications, their toxicity, and the rise of resistant strains. Since many plants have bioactive secondary metabolites with strong antifungal qualities, including alkaloids, flavonoids, terpenoids, phenolics, and saponins, ethnobotanical sources offer a viable path. Plants with …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, shifting replication domains and reshaping mutational patterns critical for cancer evolution (1,5). DNA replication timing (RT) domains serve as dynamic epigenetic organizers, partitioning the genome into early- and late-replicating regions that correlate with chromatin states, gene …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Consumer Awareness and Adoption Barriers of E-Pharmacy Services in Delhi/NCR: A Mixed-Methods Investigation
Abstract: Background: The rapid digitization of India's pharmaceutical market has positioned e-pharmacies as a transformative force; yet, consumer adoption remains significantly low despite growing awareness. Objectives: This study investigates consumer awareness levels, purchasing behaviors, trust perceptions, and adoption barriers regarding e-pharmacy services among urban Indian consumers. Methods: A sequential explanatory mixed-methods design was employed. Quantitative data were gathered via a structured questionnaire administered to 65 respondents in Delhi. Qualitative insights were …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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AI-Based Cybersecurity Framework for Protecting Smart Surveillance Infrastructure in Mumbai
Abstract: Smart city infrastructures increasingly rely on interconnected surveillance systems to ensure safety, operational efficiency, and public trust. However, the rapid expansion of IoT-based monitoring technologies has introduced new cyber risks, especially in high-density metropolitan areas. This paper proposes an AI-driven cyber resilience framework targeting smart surveillance infrastructure as a critical smart-living domain, focusing on Mumbai as a case study. Using the CIC-IDS2017 dataset, a machine learning-based intrusion detection model is …
Published in Journal Of Network security · Vol. 14, Issue 1, 2026 Read article
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Uncontrolled Cell Growth and Human Health: A Comprehensive Exploration of Cancer
Abstract: Cancer is a diverse category of diseases defined by the uncontrolled proliferation and spread of aberrant cells. It remains the major cause of morbidity and mortality worldwide. This article presents an overview of the various forms of cancer, such as carcinomas, sarcomas, lymphomas, and leukaemia, emphasising their distinct causes, symptoms, and risks. Early detection and diagnosis are emphasized as key to enhancing treatment outcomes. The article further provides an in-depth …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 1–23 Read article
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Predictive Analytics and Adaptive Learning: A Machine Learning Framework for Reducing Learning Gaps
Abstract: Most contemporary digital learning environments encounter persistent challenges when it comes to accurately identifying students who are at-risk of academic underperformance. These challenges often arise due to limited visibility in learners’ engagement levels and gaps in conceptual understanding, particularly during the early stages of a course. To address this issue, the present study proposes an early prediction framework that leverages comprehensive student-related data through the application of machine learning techniques. …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 1, 2026 · pp. 16–21 Read article
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Physicochemical Analysis of Oil Extracted from Raphia Sudanica Fruit Sold in Edu Local Government Area of Kwara State, North Central Nigeria
Abstract: Raphia sudanica, commonly called Raphia hookeri or bamboo palm fruit, is one of the most valuable species among known palm fruits found in Nigeria and is widespread in major parts of West Africa. In this study, oils extracted and analyzed from Raphia sudanica fruits (pulp and seed) revealed the respective physicochemical values; acid value (5.56, 6.10 mgKOH/g), peroxide value (2.44, 5.82 Meq/kg), iodine value (41.30, 68.10 gI₂/100 g), saponification value …
Published in Journal of Petroleum Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 67–75 Read article
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Women Empowerment: The Essential Role of Education for Women in India
Abstract: Education has long been acknowledged as one of the most powerful instruments of social transformation, and in the Indian context, it holds unique significance for women’s empowerment. The empowerment of women is central to reducing gender inequality, dismantling patriarchal norms, and achieving inclusive growth. Women’s education does not merely provide literacy; it develops autonomy, fosters confidence, and equips women with the skills necessary for meaningful participation in social, political, and …
Published in International Journal of Trends in Humanities · Vol. 3, Issue 1, 2026 · pp. 20–24 Read article
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Investigation of Pollution Status in River No. 2, Freetown, Sierra Leone, Using Physicochemical and Bacterial Indicators
Abstract: This study assessed the physicochemical and bacteriological quality of surface water in the River No. 2 watershed, Sierra Leone, through monthly sampling from March–August 2024 at upstream, midstream, and downstream sites. Analyses included temperature, turbidity, pH, electrical conductivity, total dissolved solids, ammonia, fluoride, sulfite, nitrate, lead, arsenic, chromium, and microbial indicators (Escherichia coli, fecal and non-fecal coliforms). Most physicochemical parameters met WHO drinking-water guidelines. pH (7.0–7.3), TDS (7–17 mg/L), turbidity …
Published in International Journal of Pollution: Prevention & Control · Vol. 4, Issue 1, 2026 · pp. 11–27 Read article
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An Analytical Study on Learning Difficulties in Estimation Theory Among Undergraduate Engineering Students
Abstract: Estimation Theory is a critical mathematical foundation for all engineering disciplines, enabling learners to model uncertainty, analyse signals, and derive optimal estimators. However, undergraduate students frequently struggle with its abstract properties, complex derivations, and prerequisite statistical concepts. This study investigates the key learning difficulties faced by students across multiple engineering branches using diagnostic tests, structured questionnaires, and interviews. The findings reveal that students commonly experience challenges related to weak probability …
Published in Research & Reviews : Journal of Statistics · Vol. 15, Issue 1, 2026 Read article