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250 articles for “regulatory challenges”
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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A Review on the Regulatory Study for Implementation of Schedule-M Amendments in Pharmaceutical Industries in India
Abstract: A major regulatory change in pharmaceutical manufacturing industry in India is the introduction of the updated Schedule M (2023–2024). The aims to compliance the country's Good Manufacturing Practices (GMP) with international quality standards. The review evaluates the Schedule M amendments implementation strategies, industrial impact and regulatory relevance. Legislative texts, official notices, WHO GMP reports, ICH guidelines, guidance documents of CDSCO and peer-reviewed literature were all explored as part of the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Design, Development, and Optimization of Autonomous Robots for Enhanced Performance
Abstract: Autonomous robots are transforming industries by executing complex tasks with minimal human intervention, improving efficiency, precision, and adaptability across various domains such as manufacturing, healthcare, logistics, and exploration. Their performance relies on a synergy of robust hardware design, intelligent control mechanisms, and advanced optimization techniques. This paper explores the key components of autonomous robots, including sensor integration, locomotion systems, control architectures, and decision-making frameworks that enable autonomous operation in dynamic …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 2, 2025 · pp. 22–30 Read article
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Incorporating Industrial Safety Management into Civil Engineering Works for Health and Environment
Abstract: Industrial safety management is an important tool for protecting workers, assets, and environment because it involves risk assessment, hazard control, emergency preparedness and other important practices that can enhance civil engineering construction. Civil engineering projects such as roads, bridges, dams, and water supply systems present complex occupational and environmental risks, from physical accidents on-site to ecological degradation. This paper critically examines the integration of industrial safety and management strategies into …
Published in Journal of Industrial Safety Engineering · Vol. 12, Issue 3, 2025 · pp. 25–41 Read article
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Nanotechnology In Herbal Medicine
Abstract: Herbal medicine has been widely used for centuries as a natural and holistic approach to health care. However, many herbal compounds face challenges such as low solubility, low bioavailability, instability, and the lack of targeted delivery, which affect their efficacy. The integration of nanotechnology into herbal medicine has emerged as a promising strategy to overcome these challenges and enhance the pharmacological potential of plant-derived compounds. Nanocarriers such as liposomes, solid …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 50–69 Read article
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Bio-Inspired Membranes in Oral Drug Delivery: A Pathway to Enhanced Permeability and Targeted Therapy
Abstract: Bio-inspired membranes in oral drug delivery represent a significant advancement in pharmaceutical technology, harnessing principles of natural biological systems to improve drug permeability, bioavailability, and targeted release. This review discusses the design, materials, and fabrication techniques used in bio-inspired membranes, with a focus on materials like chitosan, silk fibroin, and synthetic polymers that mimic biological structures. By exploring the mechanisms of drug permeation, such as mucoadhesion and selective permeability, bio-inspired …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 39–52 Read article
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3D Printing in the 21st Century: A Critical Review of Advances and Impacts Across Sectors
Abstract: 3D printing, or additive manufacturing, has become a pivotal technology in the 21st century, reshaping a variety of industries. This review critically examines the technological advancements that have driven the widespread adoption of 3D printing, including innovations in printing materials, precision, and speed. In sectors like healthcare, aerospace, automotive, and consumer goods, 3D printing has revolutionized product development, enabling rapid prototyping, customizations, and more efficient manufacturing processes. In healthcare, for …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 18–24 Read article
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Role of Artificial Intelligence in Simulation and Therapeutics in Neurodegenerative Diseases
Abstract: Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc., are a cause of significant mortality rates due to a lack of curative treatments and their complex nature. Traditional therapeutic methodologies have several disadvantages such as slow diagnosis and a lack of effective treatments. They mainly focused on the management of the disease rather than curing it. The integration of artificial intelligence in the simulation and therapeutics of neurodegenerative …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 19–29 Read article
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Phytomedicine in 21st century: challenges, innovations & future directions
Abstract: Phytomedicine, the use of plant-derived substances for therapeutic purposes, has experienced significant advancements and challenges in the 21st century. This review explores the current state of phytomedicine, highlighting its advantages, such as natural ingredients, fewer side effects, and cultural acceptance, as well as its disadvantages, including variable quality, lack of standardization, and limited research. The challenges faced by phytomedicine are discussed, focusing on issues of standardization, regulatory discrepancies, scientific evidence …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 86–95 Read article
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Isolated Bidirectional Flyback Converter in EV Charging and V2G Systems: A State-of-the-Art-Review
Abstract: The growing adoption of electric vehicles (EVs) and the potential of Vehicle-to-Grid (V2G) technology underscore the importance of efficient and reliable isolated bidirectional DC-DC converters in EV charging systems. The market for electric vehicles (EVs) is expanding at an exponential rate due to the worldwide trend towards sustainable transportation, with electric mobility emerging as a crucial way to lower carbon emissions and rely less on fossil fuels. This review examines …
Published in International Journal of Electrical Power and Machine Systems · Vol. 2, Issue 2, 2024 · pp. 23–32 Read article
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The Scope And Challenges Of Internet Of Things
Abstract: The Internet of Things (IoT) represents a transformative technological paradigm with the potential to reshape industries, enhance daily life, and drive innovation across sectors. This study explores the scope and challenges of IoT by examining its foundational concepts, applications, and the critical issues it faces. IoT enables seamless interconnectivity between devices, systems, and users, paving the way for advancements in smart homes, healthcare, agriculture, manufacturing, and urban development. Despite its …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 1, 2025 · pp. 1–10 Read article
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Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract: The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 27–30 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Innovative Applications of Smart Materials in Aviation: A Comprehensive Review
Abstract: Smart materials are transforming the aviation industry by offering innovative solutions that enhance performance, safety, and sustainability. The use of smart materials can enhance the efficiency, safety, and longevity of aerospace structures by sensing, responding, and adjusting to environmental changes in real time. The objective of this review is to examine how smart materials can be used in aviation, especially in the field of sensor networks, control systems, and structural …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 114–132 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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Polymer Chemistry of Ion-Selective Membranes and Hydrogels for Clinical Sodium Sensing: Advances and Perspectives
Abstract: Accurate and timely monitoring of serum sodium levels is critical in diagnosing and managing hyponatremia, a common and potentially life-threatening electrolyte disorder. Recent advances in polymer chemistry have driven the development of ion-selective membranes and hydrogels tailored for clinical sodium sensing, bridging the gap between material science and biomedical diagnostics. This review critically examines the design and synthesis of polymeric materials—focusing on block copolymers, conductive polymers, and stimuli-responsive hydrogels—used to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 895–901 Read article
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AI-Enhanced Interpretation of Cardiac Troponins: Toward Predictive Precision in Myocardial Injury
Abstract: Background: Cardiac troponins (cTn) represent the gold standard biomarkers for myocardial injury detection, yet their interpretation remains challenging due to various confounding factors and clinical contexts. Artificial intelligence (AI) technologies provide remarkable possibilities to improve the interpretation of troponin levels by utilizing pattern recognition, predictive modeling, and clinical decision-making support. Objective: This review examines the current state and future potential of AI-enhanced cardiac troponin interpretation, focusing on machine learning applications, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–9 Read article
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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A Review on Microbial Enzymes in the Food Industry: Current Innovations and Future Prospects
Abstract: Over the past few decades, microbial enzymes have become indispensable biocatalysts in food production, fundamentally revolutionizing how we approach manufacturing processes while simultaneously enhancing the quality of what we produce. Today, approximately 200 of the 4,000 known enzymes are deployed commercially with proteases, amylases, lipases, and lactases leading the charge in industrial food applications. This review brings together the latest innovations in how we use microbial enzymes for food processing, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 43–53 Read article