Trends in Drug Delivery Review Article
Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract
The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can analyze complex patient data, including genetic profiles, imaging results, and tumor characteristics, to tailor nanoparticle formulations for targeted therapy and enhance the efficacy of immunotherapies. Additionally, AI can optimize drug combinations, overcome resistance mechanisms, and monitor real-time treatment responses, ensuring that therapies are both effective and adaptive. Despite the promise of this integration, challenges such as data privacy, regulatory hurdles, and the ethical implications of AI-driven decision-making must be addressed. The combined capabilities of nanomedicine and AI represent a paradigm shift in the treatment of liver cancer, offering more personalized, efficient, and precise approaches to cancer care.
Keywords
References (15)
- Serov N, Vinogradov V. Artificial intelligence to bring nanomedicine to life. Advanced Drug Delivery Reviews. 2022;184:114194. doi:10.1016/j.addr.2022.114194
- Ho D, Wang P, Kee T. Artificial intelligence in nanomedicine. Nanoscale Horizons. 2019;4(2):365-377. doi:10.1039/c8nh00233a
- Wilson B, KM G. Artificial Intelligence and Related Technologies Enabled Nanomedicine for Advanced Cancer Treatment. Nanomedicine. 2020;15(5):433-435. doi:10.2217/nnm-2019-0366
- Heydari S, Masoumi N, Esmaeeli E, Ayyoubzadeh SM, Ghorbani-Bidkorpeh F, Ahmadi M. Artificial intelligence in nanotechnology for treatment of diseases. Journal of Drug Targeting. 2024;32(10):1247-1266. doi:10.1080/1061186x.2024.2393417
- Wang J, Liu G, Zhou C, Cui X, Wang W, Wang J, et al. Application of artificial intelligence in cancer diagnosis and tumor nanomedicine. Nanoscale. 2024;16(30):14213-14246. doi:10.1039/d4nr01832j
- Al Amin M, Emran TB, Khan J, Zehravi M, Sharma I, Patil A, et al. Research Progress of Indole Alkaloids: Targeting MAP Kinase Signaling Pathways in Cancer Treatment. Cancers. 2023;15(22):5311. doi:10.3390/cancers15225311
- Das KP, J C. Nanoparticles and convergence of artificial intelligence for targeted drug delivery for cancer therapy: Current progress and challenges. Frontiers in Medical Technology. 2023;4. doi:10.3389/fmedt.2022.1067144
- Soltani M, Moradi Kashkooli F, Souri M, Zare Harofte S, Harati T, Khadem A, et al. Enhancing Clinical Translation of Cancer Using Nanoinformatics. Cancers. 2021;13(10):2481. doi:10.3390/cancers13102481
- Kasture K, Shende P. Amalgamation of Artificial Intelligence with Nanoscience for Biomedical Applications. Archives of Computational Methods in Engineering. 2023;30(8):4667-4685. doi:10.1007/s11831-023-09948-3
- Govindan B, Sabri MA, Hai A, Banat F, Haija MA. A Review of Advanced Multifunctional Magnetic Nanostructures for Cancer Diagnosis and Therapy Integrated into an Artificial Intelligence Approach. Pharmaceutics. 2023;15(3):868. doi:10.3390/pharmaceutics15030868
- I Mazi S, M Hassen A, A Alrashed F, M. Benslimane F, A Mohamed N. Artificial Intelligence-Nanomedicine Interface: Today’s Theory Tomorrow's Technology. Archives of Clinical and Biomedical Research. 2023;07(06). doi:10.26502/acbr.50170379
- Khong J, Wang P, Gan TR, Ng J, Lan Anh TT, Blasiak A, et al. The role of artificial intelligence in scaling nanomedicine toward broad clinical impact. Nanoparticles for Biomedical Applications. 2020:385-407. doi:10.1016/b978-0-12-816662-8.00022-9
- Hassan SADH, Almaliki MNS, Hussein ZA. Development of nanotechnology by artificial intelligence: a comprehensive review. J Nanosci. 2023;13(4):915–932. doi:10.22052/JNS.2023.04.002.
- Weerarathna IN, Kamble AR, Luharia A. Artificial Intelligence Applications for Biomedical Cancer Research: A Review. Cureus. 2023. doi:10.7759/cureus.48307
- Singh AV, Ansari MHD, Rosenkranz D, Maharjan RS, Kriegel FL, Gandhi K, et al. Artificial Intelligence and Machine Learning in Computational Nanotoxicology: Unlocking and Empowering Nanomedicine. Advanced Healthcare Materials. 2020;9(17). doi:10.1002/adhm.201901862