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324 articles for “mechanical activation”
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Role of ion Regulation in Heartbeat Initiation
Abstract: The heart can beat quite 2 billion times in normal life, but the mechanism by which the guts beats is that the subject of intense research. Since the invention of pacemaker currents in 1978, several studies have shown that rhythmic changes in membrane tension (the "membrane tension clock") underlie the mechanism of automation. It's the depolarizing current activated during hyperpolarization. Therefore, when the guts cells recover, it's activated, the cell …
Published in Research and Reviews: A Journal of Medicine Read article
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Exploration of Diverse Epoxy-Based Surface Coating Methods for Enhancing Anticorrosion Characteristics
Abstract: Epoxy-based polymers, commonly referred to as polyepoxides, constitute one of the most versatile and widely adopted categories of polymeric materials due to their exceptional structural, mechanical, and chemical characteristics. Their unique macromolecular framework enables strong interfacial bonding, high mechanical stability, and superior resistance to environmental and chemical degradation, positioning them as advanced alternatives to many traditional organic corrosion inhibitors that often fail under prolonged exposure to aggressive conditions When polyepoxides …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 167–177 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Nutraceutics: Opening the Debate for a Framework for the Safety and Efficacy of Nutraceuticals Formulations
Abstract: As of right now, there is no precise definition for nutraceuticals that distinguishes them from other food-based categories such herbal products, dietary supplements, pre- and probiotics, functional foods, and fortified foods. Several studies have shed light on the possible mechanisms of action of pharmaceutically active ingredients in food, emphasizing their ability to improve health, lower the risk of disease, and promote general wellbeing. However, Nutraceuticals confront difficulties in substantiating safety …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 27–33 Read article
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Sustainable Waste Management through Polymer Recycling: A Review of Business Model and Managerial Innovation
Abstract: Plastic and other polymeric materials have transformed modern life by providing durability, versatility, and cost-effective solutions across industries such as packaging, healthcare, construction, and transportation. However, their extensive use and improper disposal have created significant environmental concerns, including plastic pollution, landfill accumulation, and marine ecosystem degradation. This review synthesizes existing literature on polymer recycling with a focus on business-model innovation and managerial practices that can support sustainable waste management at …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 155–166 Read article
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Harnessing Nature: Formulations for Colon Cancer Prevention and Treatment
Abstract: Colon cancer, a rapidly advancing disease worldwide, involves the carcinogenesis of the distal part of the intestine. This malignancy progresses through various developmental stages necessitating diverse treatment approaches. Traditional treatments include drug therapy and chemotherapy; however, emerging methods, such as the use of phytochemical compounds offer promising mechanisms for combating this disease. Phytochemical compounds derived from natural food sources, including flavonoids, tannins, resveratrol, and epigallocatechin-3-gallate, exhibit potent anti-cancer properties. They …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 11–23 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Assess the Complaint Handling and Service Recovery Practices in Hotels: The Case of Debark Town, Ethiopia
Abstract: This study aims to assess the complaint-handling and service recovery practices of hotels in Debark town. The service sector is an important component worldwide, encompassing transportation, communication, the hotel industry, tourism, etc. The target group for this study consisted of patrons, staff, and managers of the Simien National Park Hotel. Data were collected using a non-probability sampling technique, specifically convenience sampling for customers. The researcher selected a sample of 81 …
Published in International Journal of Sustainability · Vol. 2, Issue 2, 2025 · pp. 7–12 Read article
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A Study on Automatic Feedback Control by Image Processing for Mixing Solutions in a Microfluidic Device
Abstract: Precise and rapid mixing of chemical and biological reagents is a critical yet challenging aspect of microfluidic systems, often limited by laminar flow conditions and the need for manual or pre- programmed interventions. Existing mixing strategies frequently lack real-time adaptability and closed-loop control, hindering reproducibility and the execution of complex reaction protocols. This work presents an innovative automatic feedback control system utilizing the study on real- time image processing to …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 32–41 Read article
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A Shear Strength Reduction Method for an Open Pit Slope Stability Analysis Based on Finite Element Method
Abstract: Slope stability assessment of open pit mines is critically important, since it forms part of the overall productivity and safety management strategy of the mines. The aim of this work is to investigate the overall stability conditions of three (3) open pits in Gold Fields Limited, Tarkwa Ghana. Field and laboratory investigations were conducted as well as empirical methods. Finite Element Analysis (FEA) in Rocscience was carried out using the …
Published in Journal of Geotechnical Engineering · Vol. 13, Issue 1, 2026 · pp. 1–24 Read article
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Understanding Food Spoilage: Mechanisms, Shelf-Life Determination, and Safety Standards
Abstract: Food spoilage poses significant challenges to the global food industry, impacting both food safety and economic sustainability. The main causes of food quality deterioration are microbial and non-microbial spoiling. Microbial spoilage primarily results from the activity of bacteria, yeasts, and molds, which thrive under favorable environmental conditions. These microorganisms can lead to food poisoning and spoilage through the production of off-flavors, discoloration, slime formation, and the accumulation of harmful toxins. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 1, 2025 · pp. 6–9 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Platelets A Tiny Cell Fragments
Abstract: Platelets are disc-shaped, anucleate cells that are approximately 2-3 μm in diameter. Their primary function is to control hemostasis, or blood clotting, but they also play important roles in angiogenesis (the formation of new blood vessels) and innate immunity (the body's first line of defence against infection). With a diameter of just 2-3 microns, platelets are tiny, disc-shaped cells that lack a nucleus. While their main responsibility is to ensure …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 22–28 Read article
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Urban Smart Living: Home IoT Technology
Abstract: The practice of self-sufficiently regulating home appliances using various control system approaches is known as IoT smart city home automation. Many control strategies may be utilized to control the electrical and electronic appliances in the house, including the windows, refrigeration units, fans, lights, fire alarms, kitchen timers, and so on. Sync thousands of products to automate everyday tasks and create a home hub. With live cams, you can see how …
Published in Journal of Mechatronics and Automation · Vol. 11, Issue 3, 2024 · pp. 26–32 Read article
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Nuclear Reactor Safety Using Fuel Pallet: A Study
Abstract: Nuclear power stands as a vital source of low-carbon electricity, but its widespread acceptance hinges critically on unwavering safety. While public perception often focuses on massive containment buildings, intricate cooling systems, and redundant backup power, a less visible yet fundamentally crucial component plays a paramount role in safety. There is much more to these tiny, cylindrical ceramic pellets than just fissionable material. As an essential part of a reactor's defense-in-depth …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 16–23 Read article
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Comparative Evaluation of Hibiscus Cannabinus and Solanum Trilobatum Extracts as Inhibitors for C- Steel Corrosion protection in Acidic Medium
Abstract: This study analyzed the efficacy of various inhibitors in safeguarding carbon steel against corrosion in hydrochloric acid. The compounds that were subjected to testing included Acalypha indica root extract (AIRE), Hibiscus cannabinus (HC), and Solanum trilobatum (ST) leaf extracts. The investigation focused on the inhibitory efficacy through the application of gravimetric and electrochemical impedance methods. GC-MS and FTIR were employed to investigate the features of the inhibitors and co-inhibitors. Tafel …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 555–565 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Comparative Analysis of Polymer-Enhanced and Conventional Magnetorheological Fluids in E-Bicycle Semi-Active Suspension
Abstract: In light of the increased use of electric bicycles as a sustainable transport means, various mechanical challenges emerge which were absent in traditional bicycles, primarily concerning vibration isolation and riding comfort. Indeed, hub motors, batteries and the entire drivetrain system produce dynamic excitations which passive suspension cannot handle effectively. This paper presents a comparison of conventional magnetorheological (MR) fluid and the polymer-based MR nanocomposite fluid within the context of semi-active …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Enhancing Ship Roll Stabilization: Design of Active Fin Stabilizers Using Auto-Tuned PID Controllers
Abstract: The rolling motion of any type of mechanical system can be realized by the linear differential equation with some constant coefficient. In the domain of marine industries, it is observed that the stabilization of the ship’s roll motion is required due to the occurrence of the most unwanted water wave disturbances at the sea. It may cause serious types of damage to the equipment related to the ship. Active fin …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 3, 2024 · pp. 18–31 Read article