Search
707 articles for “mechanical design”
-
Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
-
Factors Affecting Mammalian Embryo Culture: A Detailed Review
Abstract: Human IVF has made remarkable progress, but optimizing the in vitro environment remains essential and crucial for supporting embryo development and improving overall clinical outcomes in assisted reproductive technologies (ART). Even with advances in complex culture media, incubator design, and laboratory workflows, embryos grown outside the body are still exposed to chemical and physical stressors that can significantly affect their developmental potential. In this review, we discuss key chemical stressors, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
-
Integrating Digital Twins, Smart Materials, and Human Machine Collaboration for Sustainable Smart Manufacturing: Smart CNC & Industry 4.0 Applications
Abstract: The rapid evolution of Industry 4.0 and the emerging transition toward Industry 5.0 have been catalyzed by the convergence of intelligent digital technologies such as digital twins, cyber–physical systems (CPS), artificial intelligence (AI), the Internet of Things (IoT), and human-in-the-loop (HITL) frameworks. These technologies have transformed traditional manufacturing into adaptive, data-centric ecosystems capable of real-time optimization and predictive decision-making. In recent years, the fusion of computer numerical control (CNC) machines, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 1–8 Read article
-
A Threshold-Weighted Mathematical Fusion Model for Epidemic Outbreak Prediction Using SEIR Residual Dynamics and Cloud-Based Machine Learning
Abstract: Accurate prediction of epidemic outbreaks is critical for effective public health management, resource planning, early warning generation, and timely intervention by municipal authorities. Traditional compartmental models such as Susceptible–Exposed–Infectious–Recovered (SEIR) offer valuable epidemiological insights and mathematical interpretability; however, they may not adequately capture the complex nonlinear relationships present in real-world urban health systems. Conversely, data-driven machine learning techniques can identify hidden patterns in large datasets but often lack epidemiological structure …
Published in Research & Reviews : Journal of Statistics · Vol. 15, Issue 2, 2026 · pp. 12–19 Read article
-
Experimental Investigation on Mechanical Characterization of Electrodeposited Shot Peened Copper Coated and Un-Coated Mild Steel
Abstract: The fatigue strength of fabricated copper coating on mild steel specimens under repeated loading and the overall number of cycles to failure has been investigated. The specimens of copper coating on mild steel substrate are fabricated by using an electro deposition shot peening method. The hardness behaviour of fabricated specimens studied and the experimental work has been carried out by using Vickers Micro Hardness under the load of 20N force. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 279–288 Read article
-
Classification and Comparison of Routing Protocols in Wireless Sensor Networks
Abstract: Recent developments and the overlap of multiple technologies, including distributed signal processing, ad-hoc network routing protocols, embedded systems, integrated circuits, micro electro-mechanical systems, microprocessor hardware, and nanotechnology, have rendered the idea of Wireless Sensor Networks (WSNs) possible. Sensor network nodes are finite with regard to energy, processing capability, and communication bandwidth. Yet, since they can vary with respect to the application and network structure, the routing protocols have received the …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 2, 2025 · pp. 35–44 Read article
-
Neuro-Symbolic Agentic AI for Autonomous Scientific Discovery: Integrating Deep Reinforcement Learning, Quantum Simulation, and XAI-Audited LLM Hypothesis Generation in Drug Target Identification
Abstract: The exponential growth of multi-omics data and the increasing complexity of disease-associated protein interactomes have rendered conventional drug target identification pipelines computationally and epistemologically inadequate. This paper presents the Neuro-Symbolic Agentic AI for Scientific Discovery (NS-AASD) framework, a unified architecture that cohesively integrates deep reinforcement learning (DRL) exploration strategies, variational quantum simulation (VQS) of protein conformational dynamics, and XAI-audited large language model (LLM) hypothesis generation within an autonomous scientific discovery …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 Read article
-
Robust Access Control Mechanisms Using VHDL Programming for IoT Security
Abstract: The Internet of Things (IoT) devices are increasingly becoming targets for criminal actors. A compromised device can result in data breaches, denial-of-service attacks, and even physical damage. While software-based security solutions are important, they are susceptible to attacks and often impose significant overhead, negatively impacting both performance and battery life. A viable alternative is provided by hardware-based security, which takes advantage of the inherent security benefits that are associated with …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 2, 2025 · pp. 6–1`9 Read article
-
A Quasi-Experimental Investigation of The Effects of Two Different Negative Pressure Levels During Open Endotracheal Tube Suctioning on Physiological Parameters in Mechanically Ventilated Patients in The PCCM ICU At Pt. B.D. Sharma P.G.I.M.S., Rohtak
Abstract: Introduction: Patients who are intubated often have difficulty clearing secretions through coughing. As a result, endotracheal suctioning is essential to minimize the risk of consolidation and atelectasis, which could impair ventilation. However, suctioning can pose several risks and complications, including bleeding, infection, atelectasis, hypoxemia, cardiovascular instability, increased intracranial pressure, and potential damage to the tracheal mucosa. The level of negative pressure applied during suctioning plays a crucial role in the …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 29–58 Read article
-
Contribution of Dalak (Massage) in the Treatment of Waja-uz-Zohar (Back Pain): A Review
Abstract: Classical Unani literature presents a detailed understanding of Waja-ul-Mafasil (diseases of bones and joints) among which Waja-uz-Zohar (low back pain) has received extensive attention. Distinguished Unani physicians meticulously described its etiology, clinical features, complications, and treatment modalities. According to Unani theory Waja-uz-Zohar is defined as pain originating from the muscles, ligaments, and connective tissues surrounding the lumbar and lumbosacral regions. Prominent scholars, such as Ibn Sina and Zakariya Razi, attributed …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 1–6 Read article
-
ANN-Based Adaptive Rotor Current Control for DFIG Wind Systems: A Comparative Dynamic Analysis
Abstract: The variability of rotor current management in Doubly Fed Induction Generator (DFIG)-based wind energy conversion systems is crucial for maintaining stability in power extraction under fluctuating wind and grid circumstances. Traditional proportional-integral (PI) controllers, despite their ease of use, frequently exhibit diminished performance when faced with parameter uncertainty, nonlinear behaviors, and rapid wind fluctuations.This paper presents an adaptive rotor current control strategy, which is an Artificial Neural Network (ANN)-based approach …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 1, 2026 · pp. 41–53 Read article
-
Attitude of Undergraduate Agriculture Students Towards Farming: Empirical Evidence From a Premier State Agricultural University in India
Abstract: Agricultural education plays a critical role in developing skilled human resources for sustaining and revitalizing the farming sector in India. Despite agriculture being the backbone of the national economy, there is increasing concern about the declining inclination of educated youth towards farming as a profession. The present study was undertaken to assess the attitude of undergraduate agriculture students towards farming and to examine selected socio-demographic, educational, economic, and psychological factors …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 15, Issue 2, 2026 · pp. 41–56 Read article
-
Thermal Effects in High-Power Laser Systems: Modeling and Mitigation
Abstract: High-power laser systems are increasingly employed in industrial manufacturing, defense, medical procedures, and scientific research due to their ability to deliver high energy density with excellent spatial coherence. However, the performance and reliability of these systems are significantly influenced by thermal effects arising from optical absorption, non-radiative recombination, and inefficient heat dissipation within laser gain media and optical components. These thermal phenomena lead to adverse effects such as thermal lensing, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 9–13 Read article
-
Framework-Based Optimization of Catalysis Efficiency through Reaction Pathway Engineering
Abstract: The rational design of heterogeneous catalysts through framework-based approaches has emerged as a transformative strategy for controlling reaction pathways and enhancing catalytic efficiency. This paper examines recent advances in the optimization of catalytic performance through engineered frameworks, including metal-organic frameworks (MOFs), zeolites, and related porous materials. By integrating computational methods with experimental validation, researchers have achieved unprecedented control overactive site architecture, reactant confinement, and elementary reaction steps. This work reviews …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 88–99 Read article
-
Design and Analysis of Thermoelectric Dc boost converter
Abstract: In today’s consumer-oriented market, researchers are increasingly focusing on harvesting energy from ambient and renewable sources to enable sustainable power generation and reduce dependency on conventional energy resources such as batteries and fossil-fuel-based electricity. The rapid growth of portable electronics, wireless sensor networks, and Internet of Things (IoT) devices has created a significant demand for low-power, long-life, and maintenance-free energy solutions. In many practical situations, frequent battery replacement is difficult, …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 4, Issue 1, 2026 · pp. 1–10 Read article
-
Assess the Complaint Handling and Service Recovery Practices in Hotels: The Case of Debark Town, Ethiopia
Abstract: This study aims to assess the complaint-handling and service recovery practices of hotels in Debark town. The service sector is an important component worldwide, encompassing transportation, communication, the hotel industry, tourism, etc. The target group for this study consisted of patrons, staff, and managers of the Simien National Park Hotel. Data were collected using a non-probability sampling technique, specifically convenience sampling for customers. The researcher selected a sample of 81 …
Published in International Journal of Sustainability · Vol. 2, Issue 2, 2025 · pp. 7–12 Read article
-
Review and Analysis of Biodegradable Polymer Composites for Sustainable Hotel Packaging Applications
Abstract: Given the fast expansion in the hospitality and tourism industry, the decline in single use packaging materials has greatly amplified the quantity of plastic wastes, as well as the destruction of the environment. The present review is dedicated to the design and use of biodegradable polymer composites (BPCs) as the sustainable solution to the hotel packaging. The paper will be a synthesis of recent developments in the field of natural …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 348–365 Read article
-
Role of Fatigue and Creep in Structural Damage: A Comprehensive Review
Abstract: Fatigue and creep are two critical degradation mechanisms that significantly influence the structural integrity and longevity of engineering materials. These phenomena arise due to different loading and environmental conditions but often coexist in various industrial applications, leading to severe material degradation over time. Fatigue primarily results from cyclic loading, where repeated stress variations induce microstructural damage and crack initiation, ultimately causing catastrophic failure. Conversely, creep occurs under sustained stress at …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 1, 2025 · pp. 22–26 Read article
-
Next-Generation mRNA Therapeutics: Self-Amplifying, Thermostable and Personalized mRNA Vaccines in the Era of Precision Medicine
Abstract: Messenger RNA (mRNA) technology has brought a major change in modern medicine, especially after its successful use in COVID-19 vaccines. However, early mRNA vaccines faced several problems such as low stability, strict cold storage requirements, and lack of personalized treatment. To overcome these challenges, next-generation mRNA technologies have been developed, including self-amplifying mRNA (saRNA), thermostable mRNA vaccines, and personalized mRNA vaccines. This article discusses the development of mRNA therapeutics, the …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 38–54 Read article
-
Effect of Aging on the Performance of Polymer Composite: A Review
Abstract: The exceptional robustness, corrosion resistance, and lightweight design, polymer composites (PCs) are crucial to modern engineering escalating the utilization of polymer composite in structural applications including aerospace engineering, automobile engineering, etc. With a greater number of positive aspects, the polymer composite also deteriorate by different environment conditions with their exposing duration considered as aging of polymer composites. However, a variety of elements influencing the ageing process determine their long-term performance. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 752–768 Read article