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186 articles for “tablet.”
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Formulation and Evaluation of Chewable Toothpaste Tablet Containing Cetylpyridinium Chloride
Abstract: The study’s goal was to create an effective formulation of Cetylpyridinium chloride chewable toothpaste pills. Cetylpyridinium chloride is a cationic quaternary ammonium chemical that has significant bactericidal, antiseptic, antiplaque, and anti-gingivitis effects. Cetylpyridinium chloride is an antiseptic with antimicrobial activities against a variety of oral bacteria and fungi. It has antiplaque and gingivitis properties. It is used therapeutically as an antiseptic agent; used alone or in combination with other drugs …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 2, 2022 · pp. 9–17 Read article
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Development and Characterization of 5-Fluorouracil Cubosomal Nanosponge Tablet for Colon Targeting
Abstract: The objective of this study was to develop nano-scale delivery system to improve nanometric size range, percentage drug entrapment efficiency, controlled release of the incorporated drug and the protection against degradation. 5-FU loaded cubosomal dispersion was prepared by the bottom up technique and formulation was characterized. From this, 5-FU cubosomal nanosponges were prepared by the emulsion solvent diffusion method using various pH dependent polymers and evaluated, encapsulation of this formulation …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 9–18 Read article
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Formulation and Evaluation of Gastroretentive Bilayered Floating Tablets of Famotidine: Effect of Formulation Variables and in vitro in vivo Evaluation
Abstract: The present investigation concerns the development of bilayered floating tablets of famotidine for prolongation of gastric residence time. An attempt was made to prepare bilayered floating tablets of famotidine by direct compression method. Two layered formulations were designed with an immediate release layer (IR) comprising of the drug, the super disintegrant Croscarmellose sodium along with the other diluents like microcrystalline cellulose and dicalcium phosphate. Three batches of immediate release layer …
Published in Trends in Drug Delivery · Vol. 2, Issue 3, 2015 · pp. 1–17 Read article
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Formulation and Evaluation of Buccal Mucoadhesive Bilayered Tablets of Enalapril Maleate
Abstract: The buccal mucoadhesive bilayered tablets of Enalapril Maleate were fabricated with objective of avoiding first pass metabolism and prolonging the duration of action. The tablets were prepared by wet granulation wherein, one layer comprised of drug and bio adhesive polymer, whereas second layer consisted of drug free backing layer of ethyl cellulose. Bioadhesive polymers like Carbopol 934P and one either of three HPMC K4M/ HPMC K15M/ HPMC K100M were employed …
Published in Trends in Drug Delivery · Vol. 1, Issue 1, 2014 · pp. 1–15 Read article
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Experimental Study on the Effect of Membranous Milkvetch and Ledebouriella divaricate Immunomodulatory Tablets on cytokine production in allergic rhinitis model mice
Abstract: We have established allergic rhinitis models for use in the treatment of allergic rhinitis with the help of the traditionall Koryo medicine administration, lade-screen Powder-extracted Membranous Milkvetch and Ledebouriella divaricate immunomodulatory tablet and the effect of lade-screen Powder on cytokine production in allergic rhinitis model mice. In the allergic rhinitis model, the administration of Membranous Milkvetch and Ledebouriella divaricate immunomodulatory tablets, along with Lade-screen Powder, demonstrated significant therapeutic effects. These …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Application of Natural and Synthetic Polymer-Based Disintegrants in the Design of Fast Dissolving Cefuroxime Axetil Tablet Composites
Abstract: The current paper examines how natural and synthetic polymer-based disintegrants can be used to design fast-soluble types of tablet composites. A model drug was chosen and tablets were prepared by the direct compression method using different polymeric excipients, such as guar gum, locust bean gum, sodium starch glycolate (SSG) and cross povidone. Eight formulations were prepared and tested on the basis of critical material and performance characteristics including thickness, hardness, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1348–1360 Read article
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Formulation Development and Evaluation of Sublingual Tablets of Enalapril Maleate Using Co-processed Superdisintegrants
Abstract: Enalapril Maleate is anti-hypertensive drug and its oral bioavailability is 40%. Sublingual tablets of Enalapril Maleate were prepared to improve its bioavailability, to avoid pre-systemic metabolism and hepatic first pass elimination. Tablets were prepared by wet granulation technique using two different superdisintegrants KYRON-T-314 and INDION-414 in the different ratio (1:1, 1:2 and 2:1) by co-processing and physical mixing. FTIR (Fourier transform infrared spectroscopy) and DSC (differential scanning calorimetry) spectroscopic studies …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 3, 2014 · pp. 24–39 Read article
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Estimation of Amoxicillin Trihydrate and Ciprofloxacin Hydrochloride from Different Marketed Brands of Tablets by UV Spectroscopy
Abstract: In the present work percentage of drug content of Amoxicillin trihyadrate and Ciprofloxacin from the marketed brands of tablets was estimated by UV spectrophotometer. Three different brands of tablets each of Amoxicillin (Mox, Novamox and Erox) and Ciprofloxacin (Cifran, Ciplox and Microflox) are purchased from the retail drug store and all the brands of tablets of Amoxicillin and Ciprofloxacin drug content was estimated from the standard calibration curve of both …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 1, 2016 · pp. 31–34 Read article
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DESIGN AND EVALUATION OF SANDWICH TABLET FOR SUSTAINED RELEASE DRUG DELIVERY OF DICLOFENAC SODIUM.
Abstract: The objective of this experiment was to create bilayer sandwich pills using the model medication diclofenac. A lengthy duration of action is provided by the combination of an immediate and sustained release layer, which lengthens the effect in the body. Diclofenac sodium has excellent antipyretic, analgesic and anti-inflammatory effects. A super disintegrating carboxyl agent, such as methyl cellulose, is used for the quick release layer of a bilayer sandwich tablet …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 2, 2023 · pp. 1–8 Read article
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Effect of Starch CMC Blend on the Drug Release from the Tablet
Abstract: Starch is frequently used as a binder and disintegrate for immediate release tablet formulation and is also used to prepare sustained release formulations. Starches from various sources show different functional characteristics; while combining with other excipients. When starch blend from various sources is used in the combination with carboxy methyl cellulose (CMC), it shows different release properties. The aim of the present work is to investigate the influence of starch-CMC …
Published in Trends in Drug Delivery · Vol. 5, Issue 1, 2018 · pp. 10–16 Read article
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The Development and Characterization of Orodispersible Tablet using Novel Natural Superdisintegrant Polysaccharide Isolated from Cassia tora Seeds
Abstract: The present work is aimed at the development and characterization of orodispersible tablet using novel natural super disintegrant, a polysaccharide isolated from Cassia tora seeds. Metformin hydrochloride (HCL) tablets were prepared separately using different concentration (2%, 5%, 7.5%) of isolated Cassia tora seed, a natural polysaccharide and croscarmellose sodium (synthetic) as super disintegrant by direct compression method. Evaluation of the tablet was done for various pre and post-compression parameter. Development …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 24–31 Read article
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Quantitative Determination of Isomeric Components of essential oils by RP-HPLC-PDA in multi-herbal tablets
Abstract: Essential oils are lipophilic and highly volatile secondary plant metabolites, principally mono- and sesquiterpenes. The widespread usage and applications in biopharmaceutics and cosmoceutics of these components drives their quality assessments criteria to be established. Gas chromatography is one of the predominantly used technique for analyzing volatile oils. Although Gas Chromatography employs estimation designs operated at elevated temperatures leading for plausible structural alterations of thermo labile compounds. Hence, a novel gradient …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 19–28 Read article
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An Overview of a Study on the Formulation of Herbal Facewash Tablets
Abstract: The global industry is seeing an increase in demand for herbal formulations due to the fact that natural medicines are safer than synthetic ones. People are starting to realize that using plants can help them achieve the key goal of having attractive, healthy skin. Reetha provides antibacterial and cleaning qualities that make it appropriate for treating acne, eliminating dead skin cells, and encouraging clear skin. Clitoria ternatea has also been …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 53–66 Read article
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Comparative Study on Oro Dispersible Tablets of Candesartan Cilexetil Formulated with Natural and Synthetic Disintegrants
Abstract: Candesartan cilexetil, a BCS class II drug with low aqueous solubility and poor bioavailability (15%), poses challenges for oral delivery. To address this limitation, the present study focuses on polymer-based inclusion complexation and composite formulation strategies to enhance solubility and dissolution behavior. The drug was incorporated into β-cyclodextrin (β-CD), a cyclic oligosaccharide polymer, by the kneading method in different drug-to-carrier ratios. Among these, the 1:1 molar ratio complex exhibited the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 687–695 Read article
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Method development and validation of RP-HPLC for simultaneous estimation of etoricoxib and Thiocolchicosidein tablet dosage forms
Abstract: Objective: A New approach became set up for simultaneous estimation of Etoricoxib and Thiocolchicoside with the aid of RP-HPLC approach.Methods: Chromatographic separations were carried using Agilent XDB C18, 150 x 4.6 mm, 5m, column with a mobile phase composition of Sodium Phospahte buffer 3.5 pH and Acetonitrile (20:80) Were delivered at a glide price of 1ml/min and the detection changed into done the usage of waters HPLC automobile sampler, separation …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 12, Issue 3, 2021 Read article
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Conversion of Siddha Churnam to Tablet—Challenges and Opportunities to Merge Siddha Wisdom with Modern Science
Abstract: AbstractWe have devised a path breaking, out-of-box method to merge the ancient scholarly wisdom of Siddhars with modern science to convert siddha churnam to tablet dosage form. Although the tablet dosage form offers accuracy when dispensed but how to fix the drug dosage in tablet for the treatment remains elusive. By simulating a gut model in a beaker and by using an advanced sophisticated instrument—spectrophotometer—we have devised a method which …
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 3, 2018 · pp. 18–23 Read article
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Formulation and In vitro Evaluation of Oral Fast Dissolving Tablets of A Novel Antidepressant Drug by Using Camphor As A Subliming Agent
Abstract: The purpose of the present investigation is to formulate fast dissolving tablets of Venlafaxine HCl, a novel antidepressant by direct compression method using camphor as subliming agent in the three different concentrations of 2%, 5% and 10%. Croscarmellose, tulsion-414 and sodium starch glycolate were used as superdisintegrants in two different concentrations of 5% and 10%. The drug-excipients compatability was ruled out through FTIR studies. A total of six formulations were …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 3, 2015 · pp. 12–18 Read article
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Design and Development of Sustained Release Tablets using Solid Dispersion of Beclomethasone Dipropionate
Abstract: In present study an attempt was made to enhance the solubility of beclomethasone dipropionate by solid dispersion method followed by formulating sustained release matrix tablet of beclomethasone dipropionate to improve the patient compliance. Beclomethasone dipropionate has poor water solubility and short elimination half-life hence solid dispersion of beclomethasone dipropionate were prepared with β-cyclodextrin and PEG 6000 as carrier by using physical mixture, solvent evaporation and kneading method. The prepared solid …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 30–41 Read article
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Bioequivalence Studies of Pantoprazole Tablets
Abstract: Pantoprazole is a most popular drug, which are used in peptic ulcer and widely distributed in India. Present study is done to assessment parameter of enteric coated Pantoprazole tablets. Two brands of Pantoprazole tablets were collected from Rampur for their assessment test. All brands demonstrated well-designed and good-looking external features. Tablets were reliable in hardness, friability, thickness, and weight. Brands f1, f2, exhibited sufficient mechanical strength to resist fracture and …
Published in Trends in Drug Delivery · Vol. 5, Issue 1, 2018 · pp. 6–9 Read article
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Methods to Overcome High Moisture and Water in Herbs during Tablet Formulation
Abstract: The present study discusses about the role of PVP in converting herbal churna to tablet form. Herbal ingredients are bound to have either high level of moisture and or essential oils and hence making tablets with such herbal ingredients pose variety of challenges such as poor flow property, compressibility, hardness and capping. PVP significantly reduce most of the limitations provided the scientific method of incorporation of the same is adopted. …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 21–24 Read article