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323 articles for “mono-”
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Aspen HYSYS Simulation of Suspension (Slurry) Process for the Production of Polyethylene
Abstract: AbstractThis study deals with the steady state simulation of polyethylene plant using Aspen HYSYS V10 simulation model. Looped reactor model is used to mimic the behaviour of the suspension (slurry) polymerization process. Effect of various operating conditions like the inflow rate of the monomer ethylene on solvent, catalyst, co-monomer and hydrogen flow rate are studied. Model predicted that the change in monomer flow rate linearly affected the process variables. Keywords: …
Published in Journal of Polymer & Composites · Vol. 6, Issue 3, 2018 · pp. 31–34 Read article
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Monoclonal Antibodies in Next Generation Animal Nutrition: Mapping Nutrient Immune Interaction Networks in Livestock Systems
Abstract: Sustainable livestock production is increasingly constrained by disease pressure, antimicrobial resistance, and declining feed efficiency under intensifying environmental stressors. Conventional nutritional strategies, while essential, remain insufficient to precisely regulate immune function and metabolic resilience. This review explores the emerging role of Monoclonal antibodies as advanced biologics in next generation animal nutrition, with a focus on mapping nutrient immune interaction networks in livestock systems. It synthesizes current knowledge on how nutrients …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Design of a Capacitive Loaded and Composite Split Ring Resonator Based Monopole Patch Antenna
Abstract: AbstractHere we have designed a monopole antenna at 2.8 GHz frequency and then we have loaded a metamaterial unit cell at the top of the monopole antenna and the same unit cell is also used as composite split ring resonator (CSRR) and incorporates with the same antenna. In both of the cases we have calculate the resonant frequency and gain of the antenna.Keywords: Metamaterials, microwave filters, splitring resonators (SRRs)\Cite this …
Published in Current Trends in Signal Processing · Vol. 8, Issue 1, 2018 · pp. 23–27 Read article
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Investigating the Effect of Spectral Variations on the Performance of Monocrystalline, Polycrystalline and Amorphous Silicon Solar Cells
Abstract: The study of spectral variations is very important in the characterization of silicon solar cells. The spectral variations of monocrystalline, polycrystalline and amorphous solar cells is studied through the spectral response with the help of spectral response evaluation meter, CEP-25HS-50SR. PVsyst 6.4.3 software is used to study the variation of air mass throughout the day and the year and to understand that how solar irradiance varies with the changing air …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 7, Issue 3, 2016 · pp. 28–36 Read article
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Synthesis, Characterization and Antibacterial Activity of Mono- and Binuclear Co(II) and Cr(III) Mixed-Ligand Complexes Derived from α-Amino Acid and 1,10- Phenanthroline with 1,3-Diaminopropan as a Spacer
Abstract: Mixed-ligand complexes of Co(II) and Cr(III) ions were synthesized from the reaction of metals chloride salts with α-amino acid (H2L1) as a primary ligand and 1,10-phenanthroline (L2) as secondary ligand. The ligand 2-(benzo[d]thiazol-2-ylamino)-2-(2-hydroxynaphthalen-1-yl) acetic acid (H2L1) has been synthesized from the condensation reaction of inobenzothiazol with 2-hydroxy-1-naphthaldehyde in the presence of HCN as three components–one pot reaction. H2L1 considered as a tridentate chelater of ONO-coordination binding type toward the metals, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 107–120 Read article
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Application of Monod and Finite Element Models for Groundwater Cleanup in the Niger Delta Area of Nigeria
Abstract: The Niger Delta region of Nigeria, known for its rich biodiversity and extensive oil and gas exploration activities, faces significant environmental degradation, including groundwater contamination. This study investigates the application of Monod kinetics and Finite Element Models (FEM) in the cleanup of groundwater contamination in the Niger Delta. Specifically, the research integrates Monod models to understand microbial degradation rates in contaminated aquifers and FEM to simulate the groundwater flow and …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 1, 2025 · pp. 39–47 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 52–58 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
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Predictive and Degradation Analysis in the Life-Cycle of Monocrystalline and Multicrystalline Photovoltaic Modules using Electroluminescence Imaging & Monitoring Studies
Abstract: AbstractSolar Technology is the cynosure of all eyes in this global era. With major thrusts towards decarbonization, improving the overall efficiency of Solar Modules is the most coveted thing in this arena. The efficiency of a Solar panel ranges between 18-25 % when it is in good working condition. There are several causes of the efficiency decreasing further. A solar panel is susceptible to a lot of damages, ranging from …
Published in Journal of Semiconductor Devices and Circuits · Vol. 7, Issue 2, 2020 · pp. 23–27 Read article
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Nonlinear Finite Element Analysis of Reinforced Concrete Exterior Beam Column Joint Subjected to Monotonic Loading
Abstract: A numerical analysis of exterior beam-column joint subjected to constant axial load on the column top and monotonic load applied at the beam tip is presented in this work. A strain-based nonlinear finite element program is developed in MATLAB R2009a. The nonlinear analysis of reinforced concrete structural member is carried out considering it as a two-phase system. The concrete in nonlinear range is considered as orthotropic material having different stress-strain …
Published in Recent Trends in Civil Engineering & Technology · Vol. 4, Issue 2, 2014 · pp. 12–21 Read article
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Monoclonal Antibody (mAb) Drugs in Cancer Therapy
Abstract: Monoclonal antibodies (mAb) are widely used in the diagnosis of diseases, detection of marker molecules and in therapy. The mAb drugs are increasingly used to treat hypersensitivity, autoimmune diseases, transplantation rejection and more importantly in cancer therapy. Although the application of mAbs in the treatment of infectious diseases is limited, the wide acceptance of these drugs in cancer therapy is remarkable. As of 2011, at least 11 FAB approved mAb …
Published in Research and Reviews : A Journal of Immunology · Vol. 2, Issue 2, 2012 · pp. 6–10 Read article
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Effect of Ethylene Glycol Monomethyl Ether on Testicular Antioxidant System in Adult Rats
Abstract: Ethylene glycol monomethyl ether (EGME), an environmental contaminant, which is widely used as a solvent especially in lacquers, paints, dyes, pesticides, liquid soap, cleaning solution & cosmetic, chemical intermediates, as a diluent for hydraulic brake fluid etc on industrial scale, has been shown to induce reproductive abnormalities in male rats. The precise nature and mechanism of action of EGME on the male reproductive system is not clear. In the present …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 1–6 Read article
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Compact Fork-shaped Monopole Antenna for Bluetooth, WLAN and Wi-MAX Applications
Abstract: This paper presents a fork-shaped monopole antenna (FSMA) with compact size. The proposed FSMA consisting a fork-shaped radiator and a partial ground plane with L-shaped and rectangular slits. The size of the proposed FSMA is 34 × 18 × 1.6 mm3 which is fed by 50Ω microstrip line. The L-shaped slit is introduced in the ground plane to enhance the bandwidth impedance of the proposed FSMA. The proposed antenna achieved …
Published in Trends in Opto-electro & Optical Communication Read article
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Quad-Band Notched Small Monopole Antenna with U-shaped Slots and SRRs for UWB Applications
Abstract: A quad-band notched small monopole antenna with U-shaped slots and SRRs for UWB applications is presented in this study. The quadruple band-notched characteristics can be achieved by embedding three U-shaped slots on the radiation patch and two split ring resonators (SRRs) near feed line, respectively. It has a tiny size, only 17 mm23 mm0.508 mm. The experimental and measured results demonstrate that the proposed antenna offers an impedance bandwidth across …
Published in Journal of Communication Engineering & Systems · Vol. 15, Issue 1, 2025 · pp. 21–31 Read article
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Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates functional genomics from OAS (4B+ sequences)(5) and structural databases (SAbDab: 10K+ structures)(6) with machine learning models achieving R=0.97 for SAP prediction.(11) We dissect biophysical mechanisms, benchmark predictive tools (DeepSP, ESM2), and engineering strategies (YTE, FW mutations) that enhance Tm by 5-10°C …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 70–83 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Impact of Pre-Operative Nebulized Lidocaine–Dexmedetomidine Combination Versus Monotherapy on Incidence, Severity, and Patient Comfort Scores of Post-Operative Sore Throat: A Randomized Controlled Clinical Trial
Abstract: Post-operative sore throat (POST) is a common issue after endotracheal intubation and can reduce patient comfort and hinder recovery. This randomized, double-blind clinical study investigated how effective pre-operative nebulized lidocaine, dexmedetomidine, and their combination are in minimizing POST. Eligible adult patients classified as ASA I–II and scheduled for elective surgery under general anesthesia were randomly assigned to three groups. Nebulization was administered 15–20 minutes before induction using standardized dosing and …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 29–35 Read article
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Dual-Band Printed Compact Trident Shaped Monopole Antenna with Inverted L-shaped For Wireless Communication
Abstract: Abstract: In the present work, printed compact trident shaped antenna with inverted L-shaped strip for dual band wireless communication. Structure of antenna is simple, and the size is 34×18 mm2. This modified inverted L-shape will give the required bandwidth with good return loss. The simulated results show the dual band from (2.5–3.2 GHz) and (5.07–5.80 GHz) with the center operating frequency at around 2.9 GHz and 5.48 GHz having reflection …
Published in Journal of Microwave Engineering and Technologies · Vol. 6, Issue 1, 2019 · pp. 13–17 Read article
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Monocrystalline Silicon Growth using the Process of Vibroturbulization
Abstract: Solar panels are powered by photovoltaic cells that capture solar energy and convert it into electrical current. Solar cells are a solar panel made from homogeneous single-crystal silicon. The cultivation of single-crystal silicon is carried out by the Czochralski method, in which, when a crystalline seed is injected onto the surface of a silicon melt, the atoms of which, when in contact with the seed, lose energy in the form …
Published in Journal of Materials & Metallurgical Engineering · Vol. 13, Issue 1, 2023 · pp. 27–33 Read article