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483 articles for “forming limit”
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Force Analysis of 2-Wheeler Swingarm Using Ansys Workbench
Abstract: Every two-wheeler carries a swingarm that forms the vital part of its suspension system. The research is done by relevant literature related to automotive component testing and is followed by current swingarm test analysis. In a review of current test systems for durability testing of swingarm, we came across Kurt Potter’s test rig, Leyni’s test bench and Reno Chako’s test rig. These test rigs accurately applied the forces as of …
Published in Journal of Automobile Engineering and Applications · Vol. 6, Issue 1, 2019 · pp. 25–32 Read article
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Land surface dynamics: A Multiphysics Approach to Modeling Mass Transport
Abstract: Land surface dynamics are governed by complex interactions among hydrological, atmospheric, and geomorphological processes that collectively drive the transport of mass across terrestrial environments. Traditional modeling approaches often isolate individual mechanisms, limiting their ability to capture the coupled feedbacks that shape landscape evolution. This study presents a multiphysics framework for modeling mass transport on land surfaces, integrating fluid flow, sediment transport, heat exchange, and chemical reactions within a unified computational …
Published in International Journal of Land · Vol. 2, Issue 2, 2025 · pp. 31–36 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
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Fermented Foods: New Prospects and Challenges
Abstract: Fermented dairy products are considered as an important part of our nutritional diet. Formerly, lactic acid bacteria were used for the production of fermented products, but now their fermentation processes produces certain physiological components possessing higher nutritional value and regular intake of such products can provide many health benefits such as anti-obesity, anti-oxidative, anti-hypertensive, prevention of urogenital infections, improved beauty and oral health. Fermented foods also play an important role …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 1, 2016 · pp. 23–33 Read article
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Green Fabrication of Glutaraldehyde-Crosslinked Chitosan/PVA Biocomposite for Heavy Metal Removal from Wastewater
Abstract: Chitosan (CS) and Polyvinyl alcohol (PVA) are polymers that possess biodegradable, biocompatible, and non-toxic properties, making them suitable for wastewater treatment applications. The primary objective of this research is to chemically modify chitosan in a novel manner to enhance its ability to remove hexavalent chromium Cr(VI) from aqueous solutions. In this study, a composite material was synthesized by crosslinking PVA and CS with glutaraldehyde (GA), resulting in the formation of …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 59–83 Read article
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Dissipative Particle Dynamics Simulation Study on the Evolution of Photoinitiated Free Radical Polymerization Crosslinked Networks
Abstract: Gradient polymer materials overcome the limitations of conventional homogeneous polymers by integrating multiple distinct functionalities within a single continuous structure. Although photoinitiated free-radical polymerization offers excellent spatial and temporal control, the underlying microscopic mechanisms governing network evolution under non-uniform light fields remain poorly understood. In this study, a mesoscale dissipative particle dynamics (DPD) model was successfully developed to couple free-radical polymerization kinetics—including initiation, propagation, crosslinking, and termination—with exponential light attenuation …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 142–158 Read article
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Material-Level Degradation of Magnetorheological Fluids Under Long-Term Cyclic Shear
Abstract: The long-term functional stability of magnetorheological fluids (MRF) remains a key limitation for their reliable use in adaptive systems and continuously operated magnetorheological devices. In this study, the intrinsic evolution of rheological properties in a commercial MRF (MRC-C1L) is systematically examined under prolonged cyclic loading, with the aim of isolating material-level degradation mechanisms independent of device-related effects. The fluid was subjected to 120,000 low-strain oscillatory shear cycles under a constant …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 101–112 Read article
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Synthesis and Characterization of PF-127 Stabilized Metformin Encapsulated Chitosan-TPP Nanoparticles
Abstract: Metformin is widely used to manage Type 2 Diabetes, but its effectiveness is limited by low intestinal absorption, high dose requirements, and a short half-life. To tackle these challenges, several nano-drug delivery systems have been designed to optimize the delivery of metformin and enhance its therapeutic efficacy. Nanoparticles (NPs) have emerged as key players in medicine, biology, and pharmacology, gaini considerable attention for their potential applications. Polymeric NPs are among …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 34–38 Read article
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A Constraint-Driven Generative Design Methodology for Modular Actuated Robotic Components in Decentralized Manufacturing
Abstract: This work formalizes a constraint-driven generative design framework for actuator-integrated robotic components intended for decentralized additive manufacturing. Conventional topology optimization typically prioritizes structural efficiency while treating actuator integration, modular interfaces, and fabrication constraints as secondary considerations. In contrast, the proposed methodology encodes these requirements as first-order geometric and mechanical constraints prior to automated material redistribution. The framework defines preserved actuator geometry, bounded design envelopes, representative loading abstractions, and manufacturability-aware domains …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 4, Issue 1, 2026 · pp. 1–12 Read article
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Failure Analyses of 16 mm Thick SA 516 GR 70 Auto Clave
Abstract: With the acceleration of global industrialization, there is a demand for high-or low-pressure storage of liquids or gases. Because of the complicated operating conditions that will inevitably encounter a possible hazard, pressure vessel design is a critical responsibility. Previous failure studies have revealed that the presence of local loads and discontinuities increases pressure vessel fracture. As a result, a detailed examination of pressure vessel steel from the standpoint of fracture …
Published in Trends in Mechanical Engineering & Technology · Vol. 12, Issue 4, 2022 · pp. 21–30 Read article
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Analysis of Combined Heating Cooling Power Plant
Abstract: Exergy analysis is a useful concept for ecology and sustainability because it can use as a common measure of resource quality along with quantity. The exergy of an energy form or a substance is a measure of its usefulness or work potential. Plant efficiency management in first instance is concerned with thermal efficiency. Ultimately plant wants to produce as much output for least expenditure of fuel. When plant efficiency deteriorates, …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 5, Issue 3, 2018 · pp. 17–32 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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HPTLC Method Development and Validation of Genistein and Daidzein Estimation in Mucuna cochinchinensis Seed Extracts
Abstract: Aim: The current study was designed with the objective to estimate the concentration of Genistein and Daidzein in ethyl acetate extract of Mucuna cochinchinensis by high-performance thin-layer chromatography (HPTLC).Methods: The separation of bioactive compounds was performed using mobile phase, Toluene: n-Butanol: Glacial Acetic Acid: Water (1:4:2:2) and detected at wavelength 254 nm. The method was validated for linearity, accuracy, precision, limit of detection (LOD) and limit of quantification (LOQ) by …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 1, 2020 · pp. 16–25 Read article
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A Study of climate change and its impact on tourism
Abstract: Tourism is clearly linked to climate, as vacationers wish spending time in open-air and travel to delight in the sky or countryside. It is then amazing that the tourism works pays slight thoughtfulness to climate and climatic transformation. Numerous of investigations on tourism and climate change is, still, beginning to raise. Though it is a generally known statement that climate change can adversely effect on tourism sector and shake the …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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RP-HPLC method for simultaneous determination of Drospirenone and Ethinylestradiol in Bulk and their Pharmaceutical dosage form
Abstract: Oral contraceptive is used to prevent the pregnancy which is contain hormones to block the release of eggs from the ovaries. Most of them contain estrogen and progesterone. Nowadays, usage of hormonal contraceptive is sharply enhancing; around 100 million of women worldwide are taking these drugs. With this drug fertility rate can be supressed as long as they want or plan their activity along with these drugs provide efficacy, reliability, …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 46–67 Read article
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Evaluation of Polyethylene Glycol (PEG)-Based Polymers for Improving Solubility and Bioavailability of Poorly Soluble Drugs
Abstract: A significant barrier to optimizing oral bioavailability is the inadequate water solubility of numerous pharmaceutical compounds. This study examined whether polymer systems utilizing polyethylene glycol (PEG) may enhance the solubility and bioavailability of a poorly soluble model drug. Multiple PEG polymers with molecular weights between 2,000 and 10,000 Da were utilized to produce PEGylated preparations. The formulations were subsequently evaluated for dissolution efficacy, medication loading capacity, particle size, and solubility …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 489–499 Read article
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Capability Database of Injection Molding Process—Requirements Study for Wider Suitability and Higher Accuracy
Abstract: AbstractGenerally, there is little disagreement that an early consideration of dimensional accuracies achieved in production is conducive to the success of development of injection molding products. While different process capability databases (PCDBs) provide guidance for a meaningful estimation of the expected part variation, the adoption of corresponding guidelines and (proprietary) software tools seems to be, however, limited in industrial practice so far. This research paper addresses the gap between the …
Published in Journal of Polymer & Composites · Vol. 5, Issue 2, 2017 · pp. 18–28 Read article
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A Review of Semiconductor Solar PV Cell and Development of Solar Radiation Estimation Models
Abstract: Today’s life could not be imagined without energy (Power). It has become an integral part of day to day life. Traditionally, dependency was there on conventional sources of energy like coal, hydroelectric etc. But they are limited resources; also, they offer residue or pollution to the environment which is not desirable. These are the main reasons that the researchers inclined themselves towards the maximum exploration and make optimal use of …
Published in Journal of Semiconductor Devices and Circuits · Vol. 5, Issue 1, 2018 · pp. 20–26 Read article
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Determination of the Antidiabetic Drug Miglitol in Pharmaceuticals by Ultra-Performance Liquid Chromatography
Abstract: Miglitol (MGL) is a drug used in the treatment of type-2 diabetes mellitus. A new analytical method employing ultra-performance liquid chromatography (UPLC) with UV-detection is presented for the determination of MGL in bulk drug and tablet forms. Analysis was performed in less than 3 min in isocratic mode on a reversed phase BEH C18 (100 mm × 2.1 mm; 1.7 µm particle size) column using phosphate buffer of pH 3.7-acetonitrile …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 2, 2018 · pp. 11–26 Read article
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Investigation of microstructure and mechanical properties of multi-pass friction stir processing on precipitation hardened aluminum alloy
Abstract: In the present study, multi-pass friction stir processing of aluminum AA2014-T651 alloy is per-formed with one and four passes. The multi-pass processing is performed at a tool rotational speed of 1000 rpm with a traverse speed of 63 mm/min. Microstructural characterization of fric-tion stir processed specimens indicated a significant grain refinement with equiaxed grains in the four pass specimen. Microhardness and tensile strength of the multi-pass specimen decreases with the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 339–349 Read article