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538 articles for “efficacy”
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A Review of Nanotechnology Application in Pharmaceutical and Health Care
Abstract: Nano drug and nano delivery systems are a fairly new but fleetly developing wisdom where accoutrements in the nanoscale range are employed to serve as means of individual tools or to deliver remedial agents to specific targeted spots in a controlled manner. Nanotechnology provides numerous advantages in treating chronic diseases by enabling precise, site-specific, and targeted drug delivery. Recently, there have been several remarkable applications of nanomedicine, including chemotherapeutic agents, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 07–17 Read article
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An Efficient LoRa-Enabled Fault Detection Using Self-Powered IoT Device
Abstract: This study describes a revolutionary internet of things (IoT) solution for effective defect detection in a variety of applications. By utilizing an IoT device that generates energy from the surroundings, the suggested solution gets around the drawbacks of conventional battery-operated gadgets. The suggested approach makes use of a self-sustaining IoT gadget that can capture energy from the surroundings to get beyond the drawbacks of conventional battery-powered IoT devices. Longer functioning …
Published in Journal of Microcontroller Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 1–13 Read article
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Regulations for Toothbrushes: A Comparative Study Between India, the US, Europe, and Australia
Abstract: Toothbrushes are essential tools for maintaining oral hygiene, making their regulation vital for consumer safety and health efficacy. This article presents a comparative analysis of toothbrush regulations in India, the United States, Europe, and Australia, highlighting the unique frameworks each region has developed to address manufacturing, distribution, and marketing challenges. In India, the Bureau of Indian Standards (BIS) and the Food Safety and Standards Authority of India (FSSAI) set safety …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 1–6 Read article
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Biometric Revolution in Automotive Security: Advancing Vehicle Protection Through Bio-Authentication Systems
Abstract: Concerns about security are rising as a result of the quick development of automobile technology and the rise in car theft and illegal entry. Both contemporary smart key solutions and older key-based systems have flaws that call for stronger security measures. By utilizing distinct physiological and behavioral characteristics, biometric authentication offers a novel way to improve vehicle security. Vehicles can provide tailored and extremely secure access control systems by combining …
Published in Trends in Machine design · Vol. 12, Issue 1, 2025 · pp. 12–19 Read article
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Tribological Characteristics of Dental Crowns
Abstract: Dental tribology is an emerging field that focuses on improving the design and material choices for artificial dental systems. This paper looks at different dental crown materials, their clinical efficacy and the consequences of tribological wear on teeth due to interfacial movement. Ceramics are commonly utilized in fixed dental restorations because of their superior mechanical and cosmetic qualities, which include exceptional fracture resistance and clinical endurance. Ceramic crowns, often used …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 550–559 Read article
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Necessity of “Cigarette Smoking De-Addiction Kiosks” at Ayush Health and Wellness Centers – An Overview
Abstract: Introduction and Socio-Demography: Cigarette is the most common form of smoked tobacco that is used globally. About 1.3 million deaths have been reported in India associated with tobacco use. India has implemented several tobacco controls measures, and as a part of that, de-addiction centers play an important role in treating addictions using various therapies. However, the discontinuation from taking de-addiction care from those allopathic centers is high due to higher …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 9–19 Read article
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Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Formulation and Evaluation of Herbal Anti-inflammatory oil using Tamarindus Indica oil, Vitex Negundo oil and Ipomoea batatas oil
Abstract: The formulation and evaluation of a herbal anti-inflammatory oil derived from the leaves of Tamarindus indica (Tamarind) Ipomoea batatas (Sweet potato) Vitex negundo (Nirgundi) aim to explore the therapeutic potential of these plants in managing pain and inflammation. Tamarind leaves are rich in flavonoids like quercetin, which primarily provide anti-inflammatory benefits by inhibiting pro-inflammatory cytokines, though their analgesic effects are moderate. Nirgundi leaves contain eugenol, known for its strong analgesic …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 01–06 Read article
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Characterization Of Bagasse Ash for Polymer Composite Applications: Reinforcement and Biocompatibility
Abstract: In present investigation, comparison of the survival rate of Bacillus megaterium inoculated in bagasse ash and charcoal is done which is widely used as a carrier material. An Isolate SB1 was isolated from the soil. This isolated SB1 was subjected for a study of cultural, morphological, and biochemical characteristics. By comparing all the studied characteristics and with reference to Bergey's manual of systematic bacteriology, Vol. II, an isolate SB1 was …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 374–378 Read article
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GreenDiagnosis: Intelligent Crop Disease Detection Using Deep Learning Algorithm
Abstract: Agriculture in parts of India relies on labour-intensive traditions, maintaining disease-free crops is crucial. Manual methods can be inaccurate, driving farmers towards AI-based solutions. AI offers a proactive approach to address real-time farming challenges. Among these is the invasion of pests, which diminishes crop quality. Combating pest-related diseases poses a challenge, prompting innovation. Effective surveillance and early detection of crop diseases play a pivotal role in ensuring global food security …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 2, 2025 · pp. 8–18 Read article
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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Developing Techniques for Controlling Different Aspects of Text Generation Such as Tone and Contents
Abstract: Large Language Models (LLMs) have shown excellent text creation quality in Natural Language Processing (NLP). However, LLMs have to satisfy ever-more-complex standards in real-world applications. LLMs are supposed to meet specific user goals, like as mimicking specific writing styles or producing material with poetic richness, in addition to eliminating inaccurate or objectionable content. Controllable Text Generation (CTG) techniques were developed in response to these diverse demands. They guarantee that outputs …
Published in Recent Trends in Programming languages · Vol. 12, Issue 2, 2025 · pp. 34–39 Read article
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Role of Polymeric Composites in Controlled Drug Release Systems
Abstract: In the realm of controlled drug release systems, polymeric composites have attracted a lot of interest as they possess several diverse characteristics that enable exact control of the drug delivery rate. This lowers adverse effects and increases the efficacy of treatment. Usually composed of biocompatible polymers combined with functional fillers like nanoparticles, ceramics, or hydrogels, these composites help to get the desired drug release patterns. Stable, biodegradable, and bioactive materials …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 453–465 Read article
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Modeling Dispersed Count Data: Evaluating the Conway–Maxwell–Poisson Regression with COVID-19 Mortality Data
Abstract: Count data are prevalent in diverse fields such as biology, healthcare, psychology, and marketing, characterized by non-negativity and inherent heteroskedasticity, often exhibiting overdispersion or underdispersion. Traditional Poisson regression, which assumes equal mean and variance, is inadequate for such dispersed data. To address this, various generalized linear models (GLMs) and their extensions, including negative binomial (NB) and Conway–Maxwell–Poisson (CMP) regressions, are utilized. This study evaluates the performance of CMP regression compared …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 · pp. 18–26 Read article
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Polysaccharide-Based Hydrogels for Sustained Drug Release in Pharmacology
Abstract: Polysaccharide-based hydrogels have showed great potential in medicine as materials for long-lasting, under control medication delivery systems. Natural polysaccharides include chitosan; alginate, agarose, and cellulose form these hydrogels. Among its many advantages are biocompatibility, biodegradability, and customising ability for various drug release rates. Reacting to pH, temperature, and ionic strength changes in the surroundings, polysaccharide-based hydrogels may swell. For usage requiring the release of therapeutic substances over an extended period …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 300–312 Read article
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Electrospun Nanofibers for Biomedical and Pharmacological Applications
Abstract: In biological and pharmaceutical sectors, nanofibers which have unique properties including a lot of surface area, tunable porosity, and high mechanical strength are very fascinating and may be made flexibly and effectively by electrospinning. More and more in biosensors, tissue engineering, drug delivery, wound healing, and medication delivery are these electrospun nanofibers being used. They may fundamentally alter the way healthcare is administered. Advanced medical applications benefit from fibres' ability …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 375–387 Read article
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Enhanced Heat Transfer in Double Pipe Heat Exchanger with Circular Fins Using Copper Nanofluid and Twisted Tape Inserts: A Computational Study
Abstract: The enhancement of convective heat transfer in a double-pipe heat exchanger utilizing circular finned twisted tape inserts and helical screw-tapes with centre rods, in conjunction with copper oxide nanofluid as the heat transfer medium was studied in this project. Computational Fluid Dynamics (CFD) simulations were conducted across Reynolds numbers ranging from 500 to 5000 to analyse heat transfer characteristics. The investigation focuses on Nusselt number improvement and friction factor analysis …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 11–22 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 41–55 Read article
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A Brief Review on Herbal Excipients
Abstract: Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 5–14 Read article
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Metal Nanoparticle: Synthesis, Properties, and Their Dermatological and Cosmetic Impacts
Abstract: Nanoparticles (NPs) are materials with dimensions under 100 nm and various shapes, such as spheres and rods. Their advancement offers transformative potential in medical and healthcare fields. The increased application of NPs across molecular biology, chemistry, medicine, and material science reflects their growing importance. Due to their large surface area, NPs enhance substance delivery through the skin, benefiting cosmetic applications by improving penetration, efficacy, and targeted delivery of active ingredients.With …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article