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618 articles for “Drug–protein interactions (DPIs)”
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Survey in Hydrazine and its Preparation, Reactions, and Their Applications
Abstract: This review concerned with hydrazine derivatives; Hydrazine is an important chemical compound used in jet engine and rocket fuel. Therefore, the European Union prohibits its sales to the developing world at 100% concentration and only permits its sales at 20-25% concentration. It is also used in industry to produce chemicals for textiles, agriculture, photographic development materials, and blowing agents used in the manufacture of foam rubber. It is also used …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 27–34 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Functional Biomolecules in Animal Nutrition: Biochemical Mechanisms and Their Impacts on Growth Performance and Health Outcomes
Abstract: Functional biomolecules have emerged as critical modulators of animal nutrition, extending beyond conventional nutrient supply to regulate biochemical and physiological processes that determine growth performance and health outcomes. This review synthesizes current knowledge on diverse classes of bioactive compounds, including amino acids, peptides, fatty acids, vitamins, minerals, phytochemicals, and microbial-derived metabolites, and their roles in livestock systems. Emphasis is placed on underlying biochemical mechanisms such as enzyme activation, nutrient signaling …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Evaluating an ai-supported experiential learning intervention: a quasi-experimental study of the joyful saturday model for student engagement and holistic development
Abstract: Student disengagement, declining academic motivation, and passive classroom participation remain major challenges in modern higher education systems. Traditional lecture-based teaching methods often fail to accommodate diverse learning styles and do not sufficiently promote active participation or collaborative learning. To address these challenges, the present study evaluates the effectiveness of Joyful Saturday, a structured experiential learning initiative designed to improve student engagement, motivation, and holistic development through interactive academic activities supported …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 79–88 Read article
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21st Century Cognitive Landscapes: Integrating ICT-Driven Pedagogies for Holistic, Inclusive Education
Abstract: The rapid advancement of Information and Communication Technology (ICT) has revolutionized digital pedagogies, reshaping modern education by improving accessibility, learner engagement, and academic outcomes. This review critically explores the psychological ramifications of digital learning environments while assessing the effectiveness of ICT tools in fostering inclusive and sustainable education. By integrating insights from contemporary research, this paper examines the impact of digital pedagogies on cognitive function, emotional health, and social interactions …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 · pp. 75–81 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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Impact of Project Complexities on Cost Overruns
Abstract: As decision-making and goal setting become more challenging due to complexity, there is growing consensus that comprehending complexity is essential for project management. However, there have been concerns expressed regarding how complexity can be quantified in a reliable way that takes into account structural, dynamic, and interaction factors. Current operational definitions of complex projects based on size and budget, have been called into doubt. What can be done is to …
Published in International Journal of Architectural Design and Planning Read article
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Impacts of Green Facades in Modern Era
Abstract: Modern architecture was an architectural movement or style centred on cutting-edge construction technologies, particularly the use of reinforced concrete, glass, and steel. The foundational goal of 21st century architecture is to create better structures that are inherently sustainable by utilising better materials and technologies. Facades are the outermost covering of a building which have the maximum interaction with the environment. A wall that is completely or partially covered with vegetation …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 44–57 Read article
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Biophilic Design in Healthcare Centre
Abstract: The human affinity towards nature is innately genetic and has a strong correlation with human well- being. This innate affiliation towards nature has been coined as Biophilia which focuses on the growing need for human interaction with nature, nature-like elements, and the natural environment in and around the built form for improving human well-being. Biophilic design can also provide physical opportunities offered through its design considerations in the realization of …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 31–50 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article
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Production of Disinfectant Using Aloe Vera (Aloe barbadensis miller) Plant Extracts
Abstract: This research work demonstrates the production of a disinfectant using aloe vera (Aloe barbadensis Miller) as main source of the raw material. The liquid content of the aloe vera was extracted using mechanical and unit operation mechanisms and the obtained raw material was subjected to heating to evaluate the effect of temperature on the characteristics of the physiochemical properties of pH, total ash, crude fat, fibre and protein, total carbohydrate, …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 17–30 Read article
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The Effectiveness of Honey Application for Oral Mucositis in Cancer Patients: A Review of Randomized Controlled Trials
Abstract: Background: Oral mucositis (OM) is a prevalent and distressing adverse outcome of cancer therapies, including chemotherapy and radiation therapy. It is an inflammatory ailment that impacts the mucous membrane inside the mouth, tongue, gums, and throat. OM can cause pain, discomfort, difficulty swallowing, and in severe cases, it can lead to infection and delayed cancer treatment. Although there are various treatments available, such as painkillers, anti-inflammatory drugs, and topical anesthetics, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 32–39 Read article
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Mobile Computing: Current Trends, Security Issues, and Future Directions
Abstract: Mobile computing is a rapidly emerging technology that is revolutionizing various sectors such as education, healthcare, tourism, transportation, manufacturing, banking, insurance, and hospitality. It is widely recognized as a potent computational tool that possesses the capability to profoundly influence society. By providing a mobile user with access to a wide range of information sources, the ability to exchange electronic messages, real-time interaction with other users, and the utilization of remote …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 1, 2023 · pp. 26–30 Read article
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Psoriasis: Causes, Symptoms, Treatment, Effect on Quality of Life and Future Therapeutic Prospects: A Detailed Review
Abstract: Objective: This review’s objective is to provide an outline of how psoriasis is caused, what are its symptoms, what are the conventional methods being employed for treatment, and how future prospects can take over the conventional methods. We also aim to put light on how psoriasis is having a huge impact on people’s life quality in various fields of life and how this effect can be measured using instruments or …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 31–49 Read article
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IoT Security: Issues, Best Practices, and Open Challenges
Abstract: The internet of things (IoT) provides the facility to connect different devices and communicate and share information over the internet. IoT has emerged as a transformative and pervasive technological paradigm, revolutionizing how we interact with our environment and infusing intelligence into everyday objects and devices. This interconnected ecosystem has unleashed a wave of innovative applications across diverse domains, including healthcare, transportation, agriculture, industrial automation, and smart cities. However, as the …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 7–13 Read article
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Studies on Extraction of Flavonoids from the Peel of Pisum Sativum
Abstract: Pisumsativum is commonly known as Pea plant and belongs to Fabaceae family. It is an herbaceous annual plant. Pea pods not only yield an adequate quality of dietary fibre but provide a substantial amount of proteins, sugars, and minerals. Globally, significant quantities of pea residue are generated, an enormous amount of which is used as animal feed. The pea pods consist of an appreciable amount of polyphenols, including phenolic acids …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 17–22 Read article
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Electromechanical Modeling of Microscale Fluidic Systems with Electro Kinetic
Abstract: Due to their capacity to carry out complex fluid manipulations at the microscale, microfluidic systems have become more popular in a variety of applications. For a variety of industries, including biomedical diagnostics, chemical analysis, and environmental monitoring, achieving precise and effective fluid control is essential. The electromechanical modeling of microscale fluidic systems using electro kinetic actuation is the main topic of this research study. We propose a thorough framework for …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 1, Issue 1, 2023 · pp. 18–22 Read article
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IoT-enabled Assistive Gloves for Individuals with Disabilities
Abstract: Every year, new technologies emerge, leaving varying degrees of impact on our daily lives, where some make a significant mark while others quickly fade into obscurity. Among the myriad of cutting-edge technologies, the Internet of Things (IoT) is particularly notable. In the present world, there are individuals who lack the ability to hear and speak, as well as those who face disabilities that hinder their social interactions. These individuals encounter …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 2, 2023 · pp. 23–30 Read article
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Evolving Face of Quality in The World Robotics Process Automation (RPA)
Abstract: Robotics Process Automation (RPA) is a technology that automates repetitive and rule-based tasks using software robots or "bots." These bots mimic human interactions with digital systems and perform tasks like data entry, validation, report generation, and system integration. RPA leverages AI and ML to improve operational efficiency and can be applied across industries and functions. Implementing RPA offers benefits such as error reduction, productivity enhancement, and cost savings. RPA is …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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Benefaction of Nutraceuticals for Human Health: Review
Abstract: Nutraceuticals are a broad category of palatable natural chemicals that are thought to offer benefits beyond their nutritional content. These can include foods high in nutrients, foods with therapeutic properties, or certain ingredients found in some foods, like dietary fiber, hydrolyzed protein, garlic, ginger, omega-3, soybean, minerals, vitamins, fortified foods, enriched foods, and even recombinant goods. People are becoming more concerned about their health due to the long work hours …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 1–12 Read article