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International Journal of Tropical Medicines Review Article

Amlodipine induced peripheral edema and gingivitis – A case report.

  1. Kishan A T john college of pharmacy

Abstract

Calcium channel a group of drugs used to treat heart disorders are called blockers. These drugs dilate blood vessels and improve blood flow to heart, these works by preventing calcium flow through ion -specific (L- type) calcium channels in the cell membrane. Amlodipine, a calcium channel blocker in the dihydropyridine class, can cause peripheral edema and drug-induced gingivitis in some patients. In this case, the patient experienced swelling in the ankles and feet, along with redness, swelling, and bleeding of the gums, which began approximately two weeks after starting amlodipine. These adverse effects are attributed to the vasodilatory action of the drug, which leads to fluid retention and increased capillary permeability, contributing to swelling. Gingival inflammation likely results from drug accumulation in the gums. Upon discontinuation of amlodipine, both the peripheral edema and gingivitis subsided. The aim of this case study is to enhance patient management for better clinical outcomes.

Keywords

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