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1260 articles for “CTLA-4”
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Effect of Energy, Lysine and Energy/Lysine Ratio on Growth Performance Nutrient Digestibility and Serum Profile of Growing Locally Adapted Turkey
Abstract: This study investigated the effects of different levels of energy, lysine and energy/lysine ratios on growth performance, nutrient digestibility, and serum biochemical indices of locally adapted turkeys. The experiment lasted for 28 days. A total of one hundred and forty-four, 4-weeks old locally adapted turkey poults were completely randomized to six dietary treatments in a 2×3 factorial arrangement, replicated twice at 12 poults per replicate. Six diets were formulated. Diets …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 01–08 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Design and Creation of Four-wheel Non- interaction Navigation Machinery
Abstract: Here we are trying to improve the steering mechanism, by rotating all 4-wheels to reduce the radius of rotation. This is a Mechatronics based project where different sensors and actuators has to employed. Electronic controller unit is going to be act as the vital element of this project through which the complete steering system has to be controlled. This electronic controller receives analog signal from the user and convert it …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 35–44 Read article
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Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
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Knowledge and Attitude of Women Regarding Mammogram and Other Screening Modalities for Breast Cancer in a Selected Hospital, Kottayam
Abstract: The present study was conducted at Caritas Hospital, to assess the knowledge and attitude of women (30–50 years) regarding mammogram and other screening modalities. The study aimed to evaluate women's understanding of mammograms and various breast cancer screening methods, gauge their attitudes toward mammograms and other screening options, investigate the relationship between women's knowledge and attitudes regarding these screening methods, explore any associations between knowledge and certain demographic factors, and …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 36–44 Read article
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The effect of cooling time and colorant pigment on the dimensional accuracy of plastic injection molded closure
Abstract: Dimensional accuracy is a critical aspect of precision injection molding, with the products generally required to conform to set tolerances. Major causes of these deviations are reported to be related to the polymer material, part geometry, injection mold design, and process parameters. This study investigated the effects of material color pigment and its interaction with process cooling time on product dimensional accuracy. This study was conducted experimentally, where three levels …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 93–100 Read article
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A Concurrent Estimation of Phytoconstituents Piperine, Quercetin and Kaempferol Present in Siddha Polyherbal Formulation Kabasara Kudineer by Rp-Hplc
Abstract: A straightforward, accurate, and precise technique was developed and validated for the simultaneous determination of Quercetin, Kaempferol, and Piperine in the polyherbal formulation Kabasura Kudineer. The sample was chromatographed using a C18 column (150x4.6mm, 5u) with a mobile phase composed of Acetonitrile and Ortho phosphoric acid in a 45:55 ratio, flowing through the column at a rate of 1ml/min. The detection wavelength for Quercetin, Kaempferol, and Piperine was set at …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 1–9 Read article
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A Pilot Study on β-lactamase Producing Escherichia coli from Bovine Milk, West Bengal
Abstract: Drug resistant bacteria have become a significant global healthcare issue that requires close attention. With regards to antibiotic resistance, E.coli and its Enterobacteriaceae family are highly notorious for their ability to swiftly spread antibiotic resistance genes, thereby posing a major concern. In order to effectively address the spread of multi drug resistant bacteria, ongoing monitoring of the microflora in milk for the presence of drug resistant genes is essential. This …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 01–05 Read article
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Development and validation of a method for simulataneous determination of tenovifir disoproxil fumarate emtriculabine and isonized in bulk and pharmaceutical dosage form using RP-HPLC with relevance to toxicological aspects
Abstract: Hence, proposed analytical methods are simple, novel, economical, rapid, sensitive, reproducible and accurate for the Simultaneous estimation of Tenofovir Disoproxil Fumarate, Emtricitabine and Isoniazid in Bulk and Phamaceutical dosage form by using RP- HPLC. This Method gives reliable assay results with short analysis time using mobile phase of Acetonitrile : 0.02M Potassium Dihydrogen Orthophosphate: water (pH 5.3) in the ratio of 60: 25: 15 respectively. Retention time was found to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 17–25 Read article
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Development and Validation of a Robust RP-HPLC Method for Rufinamide Quantification in Pharmaceutical Dosage Forms
Abstract: The creation and validation of a simple, precise, and targeted reverse phase high-performance liquid chromatographic (RP-HPLC) approach allowed for the quantification of rufinamide in pharmaceutical dosage forms. With a mobile phase of methanol and water (50:50, v/v), the technique used a gradient mode Symmetry Qualisil gold C18 column (4.6 x 150mm, 5 μm). For the detection method, a flow rate of 1 mL/min was employed at 220 nm. During a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 25–32 Read article
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Experimental investigation on impact resistance and energy absorption of multicell thin walled glass fibre reinforced polymer composite
Abstract: The objective of this study is to explore the behaviour of different types GFRP cell structures under dynamic load testing. In this study we have designed, fabricated, tested and analyzed specimens of different configurations (Cylindrical structure – 1 cell, 2 cell and 4 cell) using Glass Fibre Reinforced Polymer (GFRP). GFRP constituents are Glass fibre of 200 GSM with L-12 epoxy and K-6 hardener. Test specimens were manufactured by conventional …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 85–95 Read article
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Physicochemical Analysis of Groundwater Quality In Owerri Municipal, Imo State, Nigeria Using MATLAB and ANN Models.
Abstract: The physicochemical analysis of groundwater quality in Owerri Municipal council, Imo state, Nigeria was carried out. Fifteen water samples were randomly selected from the five villages that make up Owerri municipal council were anlayzed for physicochemical parameters using standard methods. The results from the study area showed that the temperature ranged between 26.5-28.0oC; рH ranged between 4.80-5.32. Electrical conductivity ranged between 77-166 µЅ/cm. The total dissolved solids were between 35.4-168.4mg/l; …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 1, 2024 Read article
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Stabilization of Heavy Metal Sludge to Pass the TCLP Test Using Cement with a Sinter as a Additive
Abstract: According to the U.S. Stabilisation is the best-proven technology now in use, according to the Environmental Protection Agency's definition in Title 40, Part 268 of the Code of Federal Regulations (40 CFR 268).This method prevents harmful contaminants from leaking into the environment by physically and chemically trapping them all in a matrix. The investigations used 15 different water-mixed combinations of cement, fly ash, sinter, and lime. The study also examined …
Published in Journal of Polymer & Composites · Vol. 11, Issue 10, 2023 · pp. 16–24 Read article
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Comparative Study to Assess the Attitude of Higher Secondary School Students Regarding Career Counselling in Selected Rural and Urban Schools of Kashmir
Abstract: Background: Career counselling is a process that involves working with a professional to explore and understand various aspects of one's personality, skills, interests, values, and goals to make informed decisions about your career. Aim: The main aim of the study was to assess the attitude of higher secondary school students regarding career counselling in selected rural and urban schools of Kashmir. Methods: This study employed a descriptive research design using …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 11–18 Read article
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Evaluation Of Anti Obesity Activity Of Citrus Sinensis & Citrus Limon By High Fat Diet Induced Model Using Danio Rerio
Abstract: Obesity, defined by the World Health Organization (WHO) as an abnormal or excessive fat accumulation that may impair health, is becoming one of the greatest challenges to global health in this millennium, with more than 300 million men and nearly 450 million women obese globally in 2018. Obesity turns into serious problem globally. Zebrafish model can be used extensively for drug screening due to its low maintenance cost, comparatively short …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 24–31 Read article
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Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats
Abstract: The anti-oxidant system present in our body prevents against the free radicals. Anti-oxidants were glutathione peroxidise,serum catalase,vitamin E, ascorbic acid and superoxide. In our study the plant extract of Passiflora foetidae were used to estimate the antioxidant levels in diet-induced diabetic rats. The mean of glutathione peroxide of normal rats was 92.98±1.65. "The mean of diet-induced diabetic rats was 152.50 ± 1.92*. Diabetic rats treated with sitagliptin and vildagliptin had …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 10–16 Read article
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Geopolymer Concrete with Cenosphere as Fine Aggregate: A Material Characterisation
Abstract: Geopolymer concrete (GPC) is regarded as the successor to traditional concrete as it eliminates the requirement for conventional Portland cement during its manufacturing process, hence decreasing CO2 emissions. This study employed Cenosphere, which are lightweight fine materials, to partially substitute the volume of sand in GPC. Cenosphere was utilized in proportions of 20%, 40%, 60%, and 100%. This experiment examined the fresh and hardened characteristics, durability against freezing and thawing, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 143–151 Read article
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Strategic Enhancement of Composite Strength Explored Through Comprehensive Integration of Flax Fiber and Cenosphere in Epoxy Resin Matrices
Abstract: The Current research delves into the mechanical attributes of composite specimens, integrating flax fiber and cenosphere fillers within an epoxy resin matrix catalyzed by K-6 hardener. Executing a meticulous approach involving a vacuum bagging method and a specific formulation of 10 wt.% cenosphere, 50% epoxy resin, and 40% flax fibers, the study rigorously scrutinized tensile and flexural strengths. Notably, the first specimen exhibited a peak tensile strength of 94.329 MPa, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 199–217 Read article
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Simultaneous Determination And Stability Indicating Method For Telmisartan, Metoprolol Succinate And Cilnidipine In Tablet Dosage Form.
Abstract: There are several medicinal agents available for antihypertensive activity. Telmisartan, metoprolol and cilnidipine are among them. Quantitative and qualitative analysis plays a pivotal role in safeguarding patients. Here, the estimation of these drugs was performed by using the chromatographic technique RP-HPLC. It was conducted with Phosphate buffer (pH 3.5 ± 0.01): Methanol (50:50 v/v) mobile phase. The system was operated at 1 ml/min. Drug volume to the system was 20μl. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 32–38 Read article
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Service Life Prediction of Concretes Incorporated with Fly Ash and Alccofine with respect to Chloride Ion Penetration
Abstract: Chloride-induced corrosion poses a significant threat to the degradation of reinforced concrete structures, especially in extreme environments such as marine and industrial exposure conditions, where the damage can be particularly severe. This study provides an experimental investigation utilizing three distinct water-binder ratios (0.3, 0.4, and 0.5) applied to three types of concrete mixtures: conventional concrete, concrete blended with 40% fly ash, and concrete blended with 40% fly ash and 2% …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 202–213 Read article