Search
278 articles for “and anti-aging”
-
Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
-
Exploring the Botanical and Pharmacological Significance of Aristolochia rotunda Linn (Zarawand Mudahraj): Traditional Uses, Habitat, and Bioactive Potential
Abstract: The plant Aristolochia rotunada Linn (Zarawand Mudahraj) is a member of the Aristolochiaceae family. Its rhizomes are the most valuable portion utilised in the pharmaceutical industry, mostly because of their abundance in bioactive compounds. The medicinal plant Aristolochia rotunda Linn exhibits a spectrum of pharmacological activities essential for combating hyper-uricaemia-induced inflammation. Its anti-inflammatory effects are mediated by inhibiting TNF-α, IL-1β, IL-8, and NF-κB p65 protein expression, crucial in synovial tissue. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 33–39 Read article
-
Drug Resistance – Challenges & Ayurveda Solutions – Review Study
Abstract: Antimicrobial resistance & anticancer medicine resistance has been the challenge to the medical fraternity. There are different theories postulated for developing medicine resistance, that has resulted in the debate regarding the efficacy of the medicine; there has been increasing concern as the time take for developing resistance is getting shorter and the time for development a molecule has remained constant or increasing. This resulted in medicinal resistance within few years …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 13–16 Read article
-
Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
-
Overview of Recent Advancement of Nano Stent in Pharmaceutical Application
Abstract: Interventional cardiology has witnessed remarkable progress with the evolution of nanotechnology, leading to the development of nanostents. Nanostents, characterized by their nanoscale features and innovative materials, have emerged as a cutting-edge solution for addressing the limitations associated with traditional stent technologies. This thorough analysis examines the most recent developments in the design, manufacture, and use of nanostents, emphasizing how they may completely transform vascular interventions. The first section of the …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 22–43 Read article
-
Molecular Characterization of Circulating Rota Viral Strain causing infantile diarrhoea in Tripura, North East India
Abstract: Introduction: North Eastern India is geographically distinct from rest of India and the trend of Rota viral diarrhoea among children below 5 years of age group is not well studied yet. The Government of India introduced the oral rotavirus vaccine (ROTAVAC) in 2016 as part of the Universal Immunization Programme in different parts of India. Objective: (1). To determine the proportion of circulating Rotavirus strains causing acute viral gastroenteritis (AGE) …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 6–13 Read article
-
Exploring Psychotropic Trends of Medication Use in Psychiatric Outpatients: An Observational Study at a Tertiary Care Hospital
Abstract: Background: Psychotropic medications are essential in managing a wide range of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. Prescribing habits in outpatient clinics can differ a lot depending on things like the patient’s age, background, and medical conditions. Aim: This study aims to explore the trends in psychotropic medication use among psychiatric outpatients at a tertiary care hospital, with a focus on understanding prescribing patterns, demographic factors, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 15–23 Read article
-
Evaluating the Effects of Self-Care Practices on Dermatology Patients at Sharda University Hospital
Abstract: Self-care is the ability of individuals, families and communities to promote their own health, prevent disease, maintain health, and to cope with illness with or without the support of a health or care worker." (WHO, 2020) This study looked into the demographics and self-care activities of patients who visited the Dermatology Department at Sharda Hospital. A descriptive survey design was used, with 50 participants aged 18-45 years selected using convenience …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 Read article
-
A study of The impact of Antibiotic Pollution and The types of Environmental Pollution It causes
Abstract: Antibiotics are essential biological drugs for human health and are the cornerstone of treating infections caused by various bacteria and viruses. However, they also pose a significant risk if misused, as each antibiotic is designed for a specific type of bacteria. Sometimes, due to the evolution of bacteria, many antibiotics have become ineffective and resistant to contamination and infection. Therefore, they can have the opposite effect, polluting the environment instead …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 41–46 Read article
-
Food Allergy-practical Approach
Abstract: There is a consistent increase in prevalence of food allergy (FA). The diagnosis of FA is based on thorough history supported by positive skin test, specific IgE (extract-and component-based), Basophil activation test (BAT) to reduce the need for Oral food challenge (OFC). OFC procedures may be conducted in cases of diagnostic uncertainty or to assess the presence or development of tolerance. Effective management of food allergy involves a comprehensive three-pronged …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 32–53 Read article
-
Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
-
The Review of Beetroot Composition and Benefits of Beetroot
Abstract: The genus Beta L. comprises the red beetroot, which is linked to the Betoideae branch of the goosefoot family (Amaranthaceae). Because the tuberous root of the vegetable beetroot (Beta vulgaris L.) contains a large amount of nutrients, including vitamins and minerals as well as substances with physiological activity, including betalain, inorganic nitrates, polyphenols, and folates, it is consumed in every country around the world. Like its relative turnip, the beet …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 35–42 Read article
-
Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
-
Overview of Virulence Factor of Staphylococcus sp.
Abstract: Staphylococcus is a highly virulent genus of bacteria that can cause a range of infections in humans and animals. The production of toxins, enzymes, and biofilms contributes to its ability to establish infections and evade host defenses. Understanding the characteristics and virulence factors of Staphylococcus is crucial for the development of effective prevention strategies and treatment options. Staphylococcus aureus is a significant etiological agent of nosocomial infections on a global …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 25–31 Read article
-
A Research on Formulation and Evaluation of Clove Gel for Treatment of Scabies
Abstract: Scabies remains a pervasive global health issue, with a need for more effective topical treatments. This research focuses on the formulation and evaluation of a clove oil-based gel containing eugenol, the primary bioactive component, for the treatment of scabies. Eugenol’s well-documented antimicrobial, anti-inflammatory, and ant parasitic activities make it an ideal candidate for targeting Sarcoptes scabiei, the mite responsible for scabies. The formulation was prepared by incorporating clove oil and …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 22–31 Read article
-
Impact of Various Front-line Hypertensive medication on Blood Pressure Control During Maximum Exercise Testing in Coronary Artery Disease Patients
Abstract: It has long been known that blood pressure (BP) and cardiovascular morbidity are related. It is acknowledged that blood pressure during activity may serve as a more reliable indicator than resting blood pressure, which might not accurately reflect blood pressure at other times. Goals: 1) To assess how blood pressure behaves during physical activity in individuals with coronary artery disease (CAD) whose hypertension is managed with first-line antihypertensive medications. 2) …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 37–41 Read article
-
Unraveling Ulcerogenesis: A Comprehensive Delve of Enteric & Nonenteric Ulcers
Abstract: Enteric ulcers present a multifaceted landscape encompassing both peptic and non-peptic varieties, demanding a thorough exploration of their manifestations, causes, and pathophysiology. At the forefront of understanding lie pivotal factors such as Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs usage, lifestyle choices, and stress, each wielding significant influence over ulcer development and progression. The intricate interplay of these factors underscores the complexity of enteric ulcer etiology. Helicobacter pylori infection—a prevalent culprit—inflicts …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 25–40 Read article
-
Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
-
Natural Cooling Agent: Utilizing Menthol as a Paraben-Free Preservative in Herbal Cosmetics
Abstract: The quest for natural and sustainable alternatives in cosmetic products has intensified, driving the search for effective natural preservatives. Menthol, derived from mint plants, is being recognized for its cooling properties and potential as a paraben-free preservative. This study investigates menthol’s efficacy as a preservative in herbal cosmetics, addressing consumer concerns about synthetic preservatives while ensuring product safety and longevity. This research examines menthol’s antimicrobial effects on common cosmetic contaminants …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 16–39 Read article
-
Preparation and evaluation of Herbal cosmetic
Abstract: In this investigation herbal cosmetics namely Liquorice cold cream and Catechu shampoo were prepared and evaluated. This investigation for herbal cosmetics was done for reducing toxicity for long term use in skin effectively using various herbal ingredients prepared in the laboratory such as tulsi extract, catechu extract, liquorice extract, and clove water. Liquorice cold cream provides numerous skincare benefits , thanks to liquorice extract's properties: It hydrates and nourishes dry …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 2, 2024 · pp. 26–43 Read article