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92 articles for “toxicants”
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A brief survey on Alternative and Complementary Medicine with special reference to safety, toxins and toxicological concerns
Abstract: Alternative and Complementary Medicine (ACM) is a wide range of healthcare practices that may be used within or alongside conventional medicine, and many of these practices are rapidly becoming accepted and integrated into the modern healthcare system. In addition to traditional medicine systems (e.g. Ayurveda, Unani Medicine, Traditional Chinese Medicine, and Homeopathy), ACM includes practices that utilize natural remedies including herbal medicine, phytotherapy, naturopathy, acupuncture, yoga, and meditation. While these …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 30–45 Read article
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Review on the Effects of Chemical Compounds Toxicity on Workers in Chemical Laboratories.
Abstract: Chemical laboratories are considered high-risk work environments due to the wide range of chemicals that workers handle, which may be toxic, corrosive, or flammable. Improper handling of these substances can lead to serious health problems, ranging from mild irritation to death in cases of exposure to chemical compounds such as phenols and amines, which cause various types of lung and laryngeal cancers and respiratory diseases in laboratory workers who are …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 · pp. 17–26 Read article
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Chemical Profile and Toxicity of Fresh and Dry leaves of the Essential Oils of Vetiveria zizanioides (L.) Nash. From Southwest Nigeria
Abstract: The fresh and dry leaves of Vetiveria zizanioides (L.) Nash (Gramineae) plant was collected, air dried and authenticated at the University of Ibadan Herbarium with voucher number: UIH-23237. The plant's dried, fresh leaves were hydro distilled in a Clevenger device to extract the essential oils. The oils were characterized by Gas Chromatography-Mass Spectrometry (GC – MS) while the toxicity of the essential oils was tested using brine shrimps’ lethality assay. …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 1, 2024 · pp. 44–49 Read article
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Toxic Trails: Land Degradation Induced By Pollutants
Abstract: Land degradation, driven by various pollutants, poses a significant threat to global ecosystems, agriculture, and human well-being. This review article explores the mechanisms through which pollutants, including heavy metals, pesticides, industrial chemicals, and urban waste, contribute to soil erosion, salinization, acidification, and loss of soil biodiversity. The article presents detailed case studies from regions such as China, India, Nigeria, the United States, Europe, Sub-Saharan Africa, and Australia, highlighting the diverse …
Published in International Journal of Land · Vol. 1, Issue 1, 2024 · pp. 37–45 Read article
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Zebra Fish Embryo Assay: A Wonderful Tool for Ecotoxicological Risk Assessment with Special Reference to Heavy Metals - An Overview
Abstract: In recent years, environmental pollution has become a pressing concern, prompting extensive research in aquatic ecotoxicology. With environmental degradation getting worse day by day, ecotoxicology research has gained a lot of attention. This area of study examines how biological communities in aquatic environments are affected by environmental contaminants. To unravel the toxicological mechanisms of these exogenous compounds, scientists turn to biological models. Several aquatic species, including zebrafish, toads, and big …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 56–70 Read article
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A Comprehensive Review on the Role of Antacids in the Management of Stomach Disorders
Abstract: Antacids are among the most widely used over-the-counter medications for the symptomatic management of acid-related gastrointestinal disorders, including dyspepsia, gastroesophageal reflux disease (GERD), gastritis, and peptic ulcer disease. These agents provide rapid relief by neutralizing gastric hydrochloric acid, thereby increasing intragastric pH and reducing mucosal irritation. In addition to their therapeutic benefits, the long-term and excessive use of antacids may be associated with adverse effects and toxicological concerns, including electrolyte …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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QSAR Modeling Techniques: A Comprehensive Review of Tools and Best Practices
Abstract: Quantitative Structure–Activity Relationship (QSAR) modeling has become an essential tool in drug discovery, toxicity assessment, and environmental chemistry. By correlating chemical structure with biological activity or toxicity, QSAR enables the prediction of compound behavior without extensive experimental testing. This approach not only saves time and resources but also supports ethical practices by reducing reliance on animal studies. The evolution of QSAR from basic linear models to advanced machine learning and …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 56–63 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Phytase enzyme and its remarkable effects on chicken health
Abstract: Phytase enzyme catalyzes the hydrolysis of Phytate to mono, di, tri, tetra and penta Phosphate of Myoinositol and Inorganic Phosphate. Cereals, legumes and oilseeds are the main ingredients of animal feed. Phytic acid or phytate is the chief storage form of phosphorus in the feed obtained from these plant sources. Phytate bound important mineral, metal ions and amino acids with it, and in this way it is anti-nutritional element. Simple …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 37–41 Read article
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Rotenone effects on the human body with reference to neurological disorder
Abstract: It has been claimed that the well–known neurotoxic pesticide rotenone, which is known to block the mitochondrial complex I, is strongly linked to the pathophysiology and etiology of Parkinson's disease (PD) in humans. There have been numerous analyses in the past and are still being conducted to establish a relationship between the two in order to completely comprehend the level of harm brought on by rotenone. Numerous laboratory studies shown …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 21–27 Read article
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Unraveling the Nexus: Parkinson's Disease, Alpha-synuclein, Desulfovibrio, and the Gut Microbiome
Abstract: Parkinson's disease (PD) is now recognized as a chronic condition which is once considered a highly intricate disorder involving the central, autonomic, and enteric nervous systems. The prevailing perspective attributes the disease by the formation of Lewy bodies, primarily triggered by the misfolding of α-Synuclein, leading to the demise of dopaminergic neurons in the substantia nigra. Constipation, one of the most common non-motor symptoms in PD patients, is believed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 18–28 Read article
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Desk Research on Pollutants for Ecofriendly Environmental Researchers
Abstract: Substances of foreign origin called pollutants, play a main part in alarming health hazards. The essentiality of water is being used without considering the dreadful contaminants. Arsenic, the most potential and dreadful element, is always ignored whenever there is a need for the purification of water for drinking. Rehabilitation of any affected area in view of health issues is highly mandatory as per the international provisions of Environmental legislation. In …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 2, Issue 2, 2024 · pp. 14–27 Read article
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Azepines, Chemistry, Synthesis and Reactions
Abstract: Azepines, which consist of a seven-membered cyclic compound featuring six carbon atoms, an additional nitrogen atom, and no double bonds between carbons, form a diverse group within organic chemistry. The fully hydrated form of this compound is called azepam (C6H13N). Compounds and their variants play crucial roles in pharmaceutical research due to their biologic attributes like cancer-fighting, bacteria-killing, fungus-busting, virus-suppressing, and inflammation-reducing capabilities. Various organic molecules found within nature draw …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 35–45 Read article
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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Photochemical Detoxification of Arsenic- and Mercury-Contaminated Soils: Geochemical Mechanisms and Pathways
Abstract: This study evaluates the geochemical aspects of soil detoxification in areas contaminated with arsenic (As) and mercury (Hg), emphasizing sustainable strategies for improving soil health and ensuring safe crop production. The research provides an ecological and toxicological assessment of regional soils and classifies them base on the concentration and mobility of toxic elements. Although the current levels of As and Hg do not yet present a critical risk to agricultural …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 06–10 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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In Silico Docking Analysis to Identify Therapeutic Benzoic Acid Derivatives for Acute Myeloid Leukaemia
Abstract: Background: The study is anchored to initiate subjugation against modern cancer therapy for Acute Myeloid Leukaemia (AML) which involves natural therapeutics as an alternative therapy that would degrade the prospect of adverse side effects along with anti-cancer properties. Objectives: Collate the various characteristics of Giltertinib with natural benzoic acid derivative phytochemicals for a disquisition regarding their similarities and differences in the context of providing adverse side effects. Methods: ADME toxicity …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 50–63 Read article
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Urban Eye: Manhole Surveillance with IoT
Abstract: Every nation hopes to implement the idea of the "smart city" on its own. Many different issues must be resolved in order to grow the seed into a large tree. The drainage system is one of them, and it is essential. With the right drainage system, even a tiny region can make a significant contribution to society. A sewer system can be accessed through manholes. Manholes are the best approach …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 13–22 Read article
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Exploring the Synergistic Effects of Heavy Metal contaminants on Aquatic Organisms
Abstract: Human activities have a profound effect on aquatic habitats by altering water and sediment quality, which in turn impacts resident organisms. These changes are primarily caused by pollutants from agricultural, industrial, and health-related sources. Industrial effluents, often containing hazardous heavy metals such as chromium, manganese, and lead, are a major source of environmental toxicity. The discharge of these pollutants makes water unsafe for drinking, irrigation, and industrial uses, necessitating effective …
Published in International Journal of Marine Life · Vol. 1, Issue 2, 2024 · pp. 17–20 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article