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104 articles for “gene-environment interaction”
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Leveraging Genome-Wide Association Studies for Precision Medicine in Cardiovascular Diseases
Abstract: Cardiovascular diseases (CVDs) are the leading cause of death globally, with complex etiologies involving genetic, environmental, and lifestyle factors. Genome-wide association studies (GWAS) have significantly advanced the understanding of genetic underpinnings of CVDs by identifying numerous risk loci and variants associated with various cardiovascular conditions. This review explores the potential of GWAS to drive precision medicine in cardiovascular diseases by linking genetic data with clinical outcomes, providing insights into disease …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 35–39 Read article
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Exploring the Genetic and Environmental Factors Contributing to Ovarian Cancer in Women in Mumbai, India
Abstract: Background: Ovarian cancer incidence in Mumbai has risen by 30% over the past decade, with an age-standardized rate of 9.1 per 100,000 women, contrasting stable trends in Western nations. This study investigates the interplay of genetic and environmental factors driving this disparity in Mumbai’s diverse population. Methods: A hospital-based case-control study was conducted at a hospital, enrolling 200 epithelial ovarian cancer cases (aged 30–70 years) and 400 age-matched controls. Germline …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 12–17 Read article
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Statistical Models for Predicting Genetic Variability and Disease Susceptibility
Abstract: Differences in genetics are key to understanding why some individuals are more prone to certain diseases than others. Recent advancements in genomic research, combined with statistical modeling techniques, have made significant strides in predicting disease risk based on genetic factors. This review explores the application of statistical models for predicting genetic variability and their role in disease susceptibility. We discuss traditional methods like linear regression and genome-wide association studies (GWAS), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 30–34 Read article
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Metabolites in Modern Medicine: Decoding the Future of Health and Diseases
Abstract: The end products of many metabolic processes in cells are called metabolites. Each reaction contributes a specific metabolite. Metabolites act as fingerprints of on-going biological processes. Constant changes in cellular composition due to both environmental and internal factors. By analysing the types and presence of metabolites, scientists can effectively reconstruct the inner workings of a cell or organism. In the past, analysing metabolites was a slow and tedious process, often …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article
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Association between Diabetes Type and Family History of Diabetes: A Cross-Sectional Analysis of Gender Differences and Genetic Influences
Abstract: Introduction: Diabetes mellitus DM is one of the fast-growing chronic metabolic disorder in the world, with high impact and burden in low- and middle-income country. Although genetic predisposition is a central determinant of diabetes risk, particularly for Type 2 diabetes (T2D), the contribution of familial aggregation varies across populations. In many parts of the world where diabetes is rising very fast understanding the relationship between diabetes type and family history …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 43–50 Read article
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Study on Chemical Insights into Alzheimer's Disease: Amyloid Beta and Tau Protein Interactions
Abstract: Background: Alzheimers disease (AD) is the most prevalent form of dementia, affecting millions of individuals worldwide and posing significant challenges to healthcare systems. The disease is characterized by a gradual decline in cognitive functions, particularly memory, reasoning, and the ability to perform daily activities. Aim & objective: To study chemical insights in alzheimers disease, especially amyloid beta and tau protein interactions Results & discussion: The results of this review highlight …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 37–46 Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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Monoclonal Antibodies in Next Generation Animal Nutrition: Mapping Nutrient Immune Interaction Networks in Livestock Systems
Abstract: Sustainable livestock production is increasingly constrained by disease pressure, antimicrobial resistance, and declining feed efficiency under intensifying environmental stressors. Conventional nutritional strategies, while essential, remain insufficient to precisely regulate immune function and metabolic resilience. This review explores the emerging role of Monoclonal antibodies as advanced biologics in next generation animal nutrition, with a focus on mapping nutrient immune interaction networks in livestock systems. It synthesizes current knowledge on how nutrients …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Artificial Intelligence in Microbiological Research: Methods, Applications and Implications
Abstract: Artificial Intelligence (AI) is revolutionising microbiological research by enabling the rapid analysis of complex biological data and improving the accuracy, efficiency, and reliability of scientific investigations. Recent advances in machine learning, deep learning, and bioinformatics have transformed AI into a powerful tool for studying microorganisms, their genetic composition, evolutionary patterns, and interactions with hosts and the environment. AI-driven computational models can process large and complex datasets far more efficiently than …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 Read article
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Generative AI for VR: Creating Physically Realistic Models
Abstract: Virtual Reality has revolutionized the traditional learning system by creating and interactive and engaging environment. However, its ability to show precise real-world experiences is limited due to lack of physical realism. This study investigates the potential of Generative Adversarial Network (GAN) in creating physically realistic 3D models. Proposed system incorporates deep learning techniques along with physics-based constraints to enhance model’s accuracy and usability. To achieve this, experiments were conducted on …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 3, 2025 · pp. 14–22 Read article
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Developing a RAG-PDF Reader Using Instructor XL and Falcon 7B
Abstract: This study outlines the development of a Retrieval-Augmented Generation (RAG) application, designed to efficiently extract, retrieve, and synthesize insightful responses from complex PDF documents. Leveraging advanced models like Instructor XL for generating high-quality semantic embeddings and Falcon 7B for sophisticated language generation, this system provides a robust solution for document comprehension in academic, research, and professional environments. By implementing efficient PDF text processing, embedding storage with FAISS for rapid similarity-based …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 1, 2025 · pp. 45–49 Read article
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Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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The Future is Bioengineered: Consequences, Directions, and Regulation
Abstract: Biotechnology is changing how people interact with health, life, and the environment very quickly. This article talks about how new tools in genetic engineering, synthetic biology, and bioinformatics are making it possible for scientists to build and change biological things with more accuracy than ever before. Biotechnology is changing several fields, from making personalised medical treatments and disease-resistant crops to making biofuels and materials that break down naturally. The talk …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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The Future of Electronic Communication Systems in the Digital Age
Abstract: Electronic communication networks underpin modern society, offering seamless interaction across geographical, social, and economic borders. These systems are transforming into faster, more reliable, and smarter ones as digital technologies improve. This article discusses the future of Electronic Communication Systems in the context of 5G Technology, IoT, AI, and Quantum Communication. These technologies should revolutionise data transfer by increasing capacity, lowering latency, and enabling real-time communication across platforms. Due to need …
Published in Recent Trends in Electronics Communication Systems · Vol. 13, Issue 1, 2026 Read article
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Real-Time Analysis of E-Waste Monitoring Using Data Visualization in Power BI
Abstract: The exponential growth of electronic waste (e-waste) in India poses significant environmental and public health challenges, necessitating robust monitoring, management, and disposal strategies. This project, Real-time analysis of e-waste generated across different countries in the world and also survey report of India, seeks to provide a comprehensive assessment of e-waste production patterns, utilizing real-time data to capture dynamic shifts in waste generation and collection. By leveraging Power BI for advanced …
Published in Journal of Remote Sensing & GIS · Vol. 16, Issue 2, 2025 · pp. 1–7 Read article
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Application of Natural and Synthetic Polymer-Based Disintegrants in the Design of Fast Dissolving Cefuroxime Axetil Tablet Composites
Abstract: The current paper examines how natural and synthetic polymer-based disintegrants can be used to design fast-soluble types of tablet composites. A model drug was chosen and tablets were prepared by the direct compression method using different polymeric excipients, such as guar gum, locust bean gum, sodium starch glycolate (SSG) and cross povidone. Eight formulations were prepared and tested on the basis of critical material and performance characteristics including thickness, hardness, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1348–1360 Read article
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Recent Trends in Fluid Mechanics with Emphasis on Aeroacoustics and Flow-Induced Noise Control
Abstract: Fluid mechanics continues to evolve rapidly due to increasing demands in aerospace, automotive, energy, and environmental engineering applications. Recent trends in this field highlight significant advancements in both theoretical understanding and practical implementations, particularly in complex flow phenomena. Among these, aeroacoustics and flow-induced noise control have emerged as critical research areas due to their direct impact on system performance, efficiency, and environmental sustainability. Aeroacoustics deals with the generation, propagation, and …
Published in Recent Trends in Fluid Mechanics · Vol. 13, Issue 1, 2026 · pp. 32–38 Read article
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A Comprehensive Survey on IoT-Enabled and Hand Gesture Controlled Robotic Arm Using Blynk IoT and OpenCV
Abstract: This venture presents an IoT-enabled and hand gesture-managed robot arm that operates in three distinct modes: automated control, IoT-based control via the Blynk app, and gesture-based control using OpenCV. The gadget integrates a NodeMCU microcontroller for wireless verbal exchange and management, with MQTT protocol enabling real-time messaging among the devices. In automated mode, the robotic arm plays predefined tasks autonomously. In IoT mode, users can remotely manage the arm using …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 3, 2025 · pp. 35–40 Read article
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Antibiotic Resistance in Microbes: History, Mechanisms, Therapeutic Approaches, and Strategies for Mitigation
Abstract: The global emergence of clinically significant antibiotic resistance is increasingly linked to the environment. Antimicrobials, metals, and biocides are just a few of the substances that are released into the environment through paths that are regulated by environmental regulators. Consequently, environmental regulators ought to be heavily involved in developing national and international antimicrobial resistance (AMR) measures. Antimicrobial compounds from pharmaceutical waste, agricultural runoff, and wastewater discharge contribute to the spread …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–11 Read article