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102 articles for “Biological Sample.”
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Analytical Techniques Used In Metabolomic Analysis
Abstract: Comprehensive studies regarding metabolomics provides us ample of information about the structural properties and various other parameters pertaining to the molecule under study. Metabolomics is employed for managing long-term illness such as cancer, diabetes. It’s applications also stretch to treating diseases such as tachycardia along with various cardiovascular diseases. It is used to treat inborn errors of metabolism which are found out in infants. These molecules along with processes of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 3, 2023 · pp. 52–68 Read article
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Comparative Proteomics: From Cell Lines to Clinical Samples
Abstract: Comparative proteomics is a powerful tool for understanding the molecular differences between various biological samples. It entails identifying and measuring proteins in complex biological samples to assess their abundance, modifications, and interactions under various conditions. This approach plays a crucial role in advancing biomedical research, especially in disease understanding, biomarker discovery, and therapeutic development. While cell lines are widely used for proteomic studies due to their controlled environments and reproducibility, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 30–34 Read article
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Impacts of Phthalate Plasticisers—An Emerging Issues and Concerns
Abstract: Phthalates or phthalic acid esters are the esters of phthalic anhydride used to increase the flexibility and durability of plastic products including polyvinyl chloride (PVC). Based on the molecular weight, phthalates are grouped into low and high phthalates that shows diverse applications and different mode of toxicity in various animals. The enormous production and widespread applications allow them to exist in all environments including air, water, and soil; in solid, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 9, Issue 2-3, 2020 · pp. 14–49 Read article
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Polymeric Microfluidic Chips for Rapid Point-of-Care Diagnostic Testing
Abstract: Polymeric microfluidic chips have emerged as promising platforms for rapid point-of-care (POC) diagnostic testing by integrating sample preparation, fluid manipulation, biochemical reactions, and signal detection within compact and potentially low-cost devices. Their compatibility with materials such as polydimethylsiloxane (PDMS), polymethyl methacrylate (PMMA), cyclic olefin copolymer (COC), polystyrene (PS), polycarbonate (PC), and polymer–paper composites provide considerable flexibility in device design and manufacturing. Advances in soft lithography, injection moulding, hot embossing, laser …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Health Hazards of Benzene Exposure Among Petrol Pump Attendants in North Indian Cities
Abstract: Benzene exposure is an undisputed occupational risk, notably among petrol pump attendants who come in contact with fuel vapors. Chronic exposure to benzene is linked to several conditions, such as hematological disorders, respiratory issues, and increased cancer prevalence. This research aims to assess the health effects related to benzene exposure amongst petrol attendants in the northern cities of India. A cross sectional study was conducted at each petrol pump in …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 2, 2025 · pp. 36–43 Read article
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Immunoassay and its Biotechnological Relevance
Abstract: Immunoassays are bioanalytical methods to quantify of the analyte (antigen) depending on its reaction with an antibody. These methods are based on a competitive binding reaction between a fixed amount of labeled analyte and a variable amount of unlabelled sample analyte for a limited amount of binding sites on a highly specific anti-analyte antibody. Applications of immunoassays are diagnosis of diseases, therapeutic drug monitoring, clinical pharmacokinetic and bioequivalence studies in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 7, Issue 1, 2017 · pp. 17–28 Read article
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Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
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SCIENTISTS REINVENT LOW ENERGY NUCLEAR REACTION (LENR)/COLD FUSION
Abstract: Two of the researchers of The University of Utah, USA in 1989 named Dr. Martin Fleishmann and Stanley Pons declared that they had discovered a sustained nuclear fusion reaction at room temperature during electrolysis experiment that could solve the problem of energy requirement on this planet. The cold fusion reaction, also called low energy nuclear reaction (LENR) takes place at room temperature, unlike conventional fusion reaction where temperature required is …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 3, 2024 Read article
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A Comprehensive Review of Analytical Method – Development and Method Validation of Digoxin Tablets
Abstract: The main objective of this review is to give an outline of the method development and validation process of digoxin, and this review covers the different types of spectroscopic and chromatographic techniques, such as HPLC, UHPLC-Tandem mass spectroscopy, TLC, and LC-MS. A novel method for the determination of digoxin in biological samples has been developed and validated, focusing on improving sensitivity, specificity, and reproducibility. The method was validated in terms …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 47–58 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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High Performance Liquid Chromatography: A short review
Abstract: High performance liquid chromatography ( HPLC) is an important qualitative and quantitative technique commonly used for estimating chemical , pharmaceutical and biological samples. It is the most versatile, reliable, safest and fastest chromatographic technique for the quality control of drug components. This article was prepared with the intention of reviewing various aspects of HPLC, such as theory, instrumentation, form, application and limitation.
Published in Emerging Trends in Chemical Engineering · Vol. 7, Issue 2, 2020 · pp. 20–26 Read article
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Refractive Index Measurement Using Integrated Fiber Optics Triangulation Technique
Abstract: Quantitative and qualitative analytical techniques are of considerable importance for the purpose of detection, identification and measurement in biomedical application. Over the years, several methods have been developed to detect and quantify various biological samples. However each of this method presents certain limitations pertaining to its sensitivity, accuracy, and reproducibility. The recent trend to improve biochemical analysis is to provide a platform, which is more sensitive, accurate, portable, rapid and …
Published in Recent Trends in Sensor Research & Technology · Vol. 9, Issue 3, 2022 · pp. 32–37 Read article
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Computational Analysis of Epithelial Stratum and Physical Condition of Human Kidney Cells and Liver Cells Using Non Destructive Testing Technique by Scanning Acoustic Microscope
Abstract: The present work deals with the methodology governing scanning acoustic microscope (SAM) for non-destructive testing of biological samples (liver cells and kidney cells). Acoustic microscopy was performed on liver cells and kidney cells for measuring their thickness and also to determine their shapes. This technique was also used for evaluation of internal damage to cells. SAM images were taken for further qualitative and quantitative assessments. Using the quantitative data obtained …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 1, 2015 · pp. 1–4 Read article
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Opportunities for India to collaborate for occupational Health and Safety: A review
Abstract: The safe and healthy work environment is a fundamental human right in India. 63.6% are estimated to be in working group, where more than 90% work in the informal economy and less than 10% are in formal economy. Workers are exposed to various risk which are not assessed due to lack of skilled human resource. Collaboration can be undertaken through joint/multilateral programs, research studies particularly in frontier areas, institutionalized exchange …
Published in Research and Reviews: A Journal of Medicine · Vol. 1, Issue 1, 2011 · pp. 116–122 Read article
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Method Development and Validation by HPLC: A Brief Review
Abstract: High-performance liquid chromatography (HPLC) is a significant analytical technique, usually used for the determination and separation of pharmaceutical and biological samples. This is most adaptable, safe, reliable, and fast chromatographical method for quality control of drug samples. The objective behind the present study was to focus on different features of HPLC, such as principle, types, instrumentation, HPLC method development and validation along its application.
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 1, 2025 · pp. 27–39 Read article
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Antimicrobial, Antioxidant Evaluation of Majestic Darjeeling Green and Black Tea during Storage
Abstract: Three months storage in ambient temperature and humidity causes the changes in biochemical (antioxidant) and antimicrobial properties of Darjeeling green and black tea. Having higher extent of total polyphenol and non-enzymatic antioxidant flavonoid content green teas are able to show higher antioxidant and antimicrobial activities against different microorganisms. Due to manufacturing procedures (greater extent of fermentation) some of the enzyme activities (including antioxidant enzyme catalase, phenylalanine ammonia lyase) are lowered …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 3, 2015 · pp. 24–34 Read article
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Recent Advancements and Comprehensive Review on Hyphenated Techniques
Abstract: Hyphenated techniques represent a powerful class of analytical methods that combine two or more established techniques – typically a separation method with a spectroscopic detection technique – to achieve enhanced analytical performance. First introduced by Hirschfeld in 1980, the term “hyphenation” refers to the online coupling of such methods, enabling more precise, sensitive, and comprehensive analysis of complex samples. These techniques exploit the strengths of individual methods while overcoming their …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 37–50 Read article
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Valorization of Human and Cattle Dental Waste into Functional Composite Biomaterials: A Detailed Comparative Analysis
Abstract: This study investigates the conversion of human and cattle (goat and cow) teeth into bioactive hydroxyapatite-based composites and presents a detailed comparative evaluation of these biogenic materials with laboratory-synthesised (synthetic) hydroxyapatite (HAp). In this work, hydroxyapatite was extracted from human and bovine teeth through controlled calcination and milling, while synthetic HAp was prepared using a standard wet chemical precipitation route. All materials were subsequently sintered at 900 °C and fabricated …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 340–354 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Levels of Environmental Pollutants and Urinary 1-Hydroxypyrene among Foundry Workers
Abstract: Environmental and biological monitoring was conducted to measure the Total Suspended Particulate Matter (TSPM), SO2,NOx and 1-OHP among foundry workers. Among the various sampling locations melting (2466 μg/m3) and fettling (2951 μg/m3) recorded higher concentration of TSPM. The concentration of NOx and SO2 ranged between 288– 352 μg/m3 and 3.11-10.97μg/m3,respectively. Among the various heavy metals analysed, the concentration of zinc and nickel was the maximum. Although the environmental monitoring study …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 8–15 Read article