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21 articles for “ACE gene”
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Role of Genetics in Improving Fitness and Sports Performance
Abstract: Research indicates that variations in specific genes affects sports performance, comparing athletes with nonathletes. The genes that have been examined the most in relation to athletic performance are ACE and ACTN3. Strength and endurance have been associated with these genes, which also affect the type of fiber that makes up muscles. Sports performance factors primarily affected by genes are intrinsic motivation to exercise, power and endurance potential, training response to …
Published in Recent Trends in Sports · Vol. 1, Issue 2, 2024 · pp. 28–34 Read article
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Risk Assessment of Batch Sulfonation Process using Fault Tree and Bowtie
Abstract: The current study looks into the batch reactor's sulfonation reaction's safety features. Acetanilide, thionyl chloride, and chlorosulphonic acid are used in the sulfonation reaction under consideration to generate acetyl sulphonyl chloride as well as by-products such HCl and SOx. Steam starts the process, which is exothermic in nature. Water is then chilled to maintain a temperature of 50°C and a pressure of one atmosphere. The Hazard and Operability (HAZOP) analysis …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 3, 2024 · pp. 50–56 Read article
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The Association Between Intergenerational Trauma, Perceived Social Support and Post Traumatic Growth among Young Adults
Abstract: This study explores the intricate relationship between intergenerational trauma, perceived social support, and post-traumatic growth (PTG) among young adults in the Indian subcontinent. Drawing on a sample of 199 participants, the research examines how adverse childhood experiences (ACE) transmitted across generations impact individuals' psychological well-being and their capacity for growth. In particular, the study looks into how perceived social support from friends, family, and other people can help to moderate …
Published in International Journal of Children · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Effect of Adverse Childhood Experiences on Adult Attachment Styles and Help Seeking Behaviour Among Youth
Abstract: Psychological development is deeply influenced by early environments, where personal experiences, cultural norms, and structural factors intersect. Beyond individual adversity, societal conditions shape cognitive, emotional, and social functioning, ultimately influencing attachment patterns and help-seeking behaviour in adulthood. The current study explores the influence of adverse childhood experiences on adult attachment styles and help-seeking behaviour among youth. 140 participants (70= males, 70= females) aged 18-25 years were involved in the study. …
Published in International Journal of Children · Vol. 2, Issue 2, 2025 · pp. 25–34 Read article
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Recent Advances in Transition Metal Complexes with Phenyl Acetic Acid and Pseudo Halogen: Synthesis, Characterization and Applications
Abstract: A well established strategy is to introduce a biologically relevant organic molecule in coordination sphere of transition metal complexes to increase the selectivity and biocompatibility. Phenylacetic acid (PAA), an organic molecule with a phenyl functional group and a carboxylic acid functional group, is a phenylalanine that is generated from the naturally occurring auxin, which is extensively present in plants. The most promising outcomes in the battle against cancer and microbes …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 68–78 Read article
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Quantitative Mass Balance Modelling for the Synthesis and Production of Ten High-Volume Insecticides
Abstract: This study presents a detailed quantitative mass balance analysis for the industrial synthesis and production of ten high-volume insecticides: acequinocyl, acetamiprid, acynonapyr, alpha-cypermethrin, benzpyrimoxan, bifenazate, bifenthrin, bistrifluron, broflanilide, and bromofos, focusing on material flows, process efficiencies, and environmental implications. These compounds, spanning diverse chemical classes like neonicotinoids, pyrethroids, and meta-diamides, are essential for crop protection but pose challenges due to resource-intensive syntheses and waste generation. For each insecticide, standardized manufacturing …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 36–55 Read article
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Responses of Phytoplankton Community Structure to Polycyclic Aromatic Hydrocarbon Constituents in Imo River, Oyigbo, Niger Delta, Nigeria
Abstract: Phytoplankton perform a pivotal role in the food chain and serve as indicator species in environmental studies. Polycyclic aromatic hydrocarbons (PAHs) are toxic group of divergent chemicals with two or more aromatic rings coalesce side by side representing serious persistent organic contaminants posing environmental risk to aquatic life and human. Imo River receive contaminants from illegal oil refinery. The study was conducted to assess the responses of phytoplankton community structure …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 1, 2025 · pp. 45–53 Read article
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Angioedema-Diagnosis & Management
Abstract: Angioedema (AE) encompasses a diverse range of conditions categorized into three main groups: (1) angioedema mediated by histamine (AE-H); (2) angioedema mediated by bradykinin (AE-BK); and (3) angioedema with an unknown mechanism (AE-UNK). It can manifest on any part of the body, though commonly affected areas include the face, lips, mouth, throat, larynx, extremities, genital regions, and gastrointestinal tract. AE-H can occur by itself or in conjunction with chronic urticaria, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 9–21 Read article
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Description & Prevention of Omicron
Abstract: November 9, 2021, Botswana becomes the first country to recognise it (Nov 11 2021). The new variant (B.1.529) has been represented in 77 countries. Omicron presents 32 changes in spike protein Scribd, restricting the point of interaction with the ACE2 receptor protein. Computational shows and components’ recreation has been applied to investigate the collaboration between the SARS-CoV-2 RBD and the ACE2 receptor. The receptor-binding domain (RBD), which more barely joins …
Published in Research & Reviews: A Journal of Pharmacognosy Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Structural, Optical, Surface and Gas-Sensing Properties of rGO/Sn1-xZnxO₂ Nanocomposites
Abstract: rGO/Sn₁₋ₓZnₓO₂ nanocomposites with x = 0.00–0.75 were synthesized by sol–gel auto-combustion followed by wet impregnation with reduced graphene oxide. The adopted synthesis route enabled homogeneous Zn incorporation into the SnO₂ matrix and uniform distribution of rGO, leading to improved structural integrity and interfacial contact between the two components. XRD confirmed a dominant tetragonal cassiterite SnO₂ structure, while FTIR, FESEM, EDS, UV–visible, and BET analyses verified oxide–rGO coupling, Zn-dependent structural modification, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Multiple Sclerosis: A Brief Overview of the Disease, Its Pharmacotherapy
Abstract: Multiple Sclerosis is an autoimmune disorder mostly affecting individuals aged between 20-40. In this disorder, the optic, vertebral, and central nervous system nerves are primarily impacted. It is a neurological condition that worsens over time and is characterized by inflammation and the breakdown of the sheath that surrounds and shields the nerve fiber. Common symptoms may include muscle weakness, numbness, tingling, fatigue, vertigo, tremor, vision complications, pain, Lhermitte sign, sexual …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Drug-Induced Liver Injury: Hepatotoxicity and Treatment - A Literature Review
Abstract: Drug-induced liver injury (DILI) is a major clinical and regulatory challenge, posing risks to patient safety and drug development worldwide. As the primary organ responsible for xenobiotic metabolism, the liver is particularly susceptible to toxic injury from prescription drugs, over-the-counter medications, herbal products, and dietary supplements. Drug-induced liver injury (DILI) accounts for a substantial proportion of acute liver failure cases and remains a leading cause of post-marketing drug withdrawal. Its …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 1–17 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
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Comparative Analysis of Dip and Spray Techniques with Ethanol, Polyvinyl Alcohol, and Acetone Hydrophobic Glass Slides with Al2O3 Coating
Abstract: The hydrophobic effects of Al₂O₃ coatings on glass slides are investigated in this work by comparing dip and spray procedures using three distinct solvents: acetone, polyvinyl alcohol (PVA), and ethanol. Using both dip and spray techniques, the experimental design systematically applies Al₂O₃ coatings on glass slides. Then, the effect of the chosen solvents on hydrophobicity is investigated. Delineating the complex interaction between coating processes and solvent options requires careful analysis …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 45–51 Read article
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Exploring Chicken Sternal Cartilage as an Alternative Source of Bioactive Protein Hydrolysates
Abstract: There is a growing concern on the correct use and dispose of the by-products of the food industry, and chicken slaughterhouse, such as cartilage, combs, and wattles may be strong candidates as a protein source for bioactive peptides, however it is crucial to understand how the proteolysis process may affect the peptide profile and their bioactivity. The objective of this work was to obtain protein hydrolysates from chicken sternal cartilage …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 3, 2025 · pp. 15–28 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Investigation of Residual Stress, and corrosion behavior of AA6082/Al 2 O 3 /C/ Si 3 N 4 Composite Material
Abstract: The main objective of the current study was to create AA6082/ Al2O3/C/Si3N4 Composite Material by the use of stir casting. The properties of the AA6082/ Al2O3/C/ Si3N4 Composite Material shown a significant improvement, with a micro-hardness rise of 13.5% and a residual stress decrease of 60%. As the testing parameters were increased, the residual stress of the AA6082/ Al2O3/C/ Si3N4 Composite Material rapidly decreased from -65MPa to -15MPa. An electromagnetic …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1104–1109 Read article