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42 articles for “oral dosage”
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Patents on Gastroretentive Drug Delivery System: An Overview
Abstract: Background: Conventional oral dosage forms have poor bioavailability and recurrent dosing of the drug is needed to maintain the effective therapeutic concentration in the body. It may lead to poor patient compliance and fluctuations in the plasma level of drug especially in the chronic diseases and disorders. Origin: In outlook of this, to enhance the efficiency and bioavailability of the drug, gastroretentive drug delivery system is developed which can prolong …
Published in Trends in Drug Delivery · Vol. 8, Issue 1, 2023 · pp. 22–30 Read article
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Pediatric and Geriatric Formulation Tailoring Dosage Form for Age-Specific Needs
Abstract: This comprehensive review addresses the critical challenges and advancements in the formulation of oral medications for pediatric and geriatric populations, who often face unique pharmacokinetic and pharmacodynamic differences. The World Health Organization highlights that nearly 50% of long-term medications are not adhered to, with significant implications for health outcomes. Pediatric patients, due to their developmental stages, and geriatric patients, due to age-related physiological changes, require tailored drug formulations to enhance …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 89–103 Read article
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Stomach Mimicry of A-Forte for Pharmacokinetic Insight
Abstract: Drug absorption from solid dosage forms after oral administration depends on the release of the drug substance from the drug product, the dissolution or solubilization of the drug under physiological conditions, and the permeability across the gastrointestinal tract. In vitro dissolution may be relevant to the prediction of in vivo performance. To evaluate the in vitro dissolution of A-forte, a siddha proprietary medicine and the influencing factors, a study of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 2, Issue 2, 2015 · pp. 8–12 Read article
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Oral Capsaicin Ingestion: A Brief Update Dose, Tolerance and Side Effects
Abstract: Capsaicin has attracted increasing scientific attention in recent years relative to its potential pain relief properties, with oral ingestion providing a useful mode of capsaicin delivery. Yet, despite many exciting new findings in this area, there appears to be significant discrepancy across current research so far about an established oral dosage for use in scientific trials. In an attempt improve future research in this area, this commentary provides a short …
Published in Research & Reviews : Journal of Herbal Science · Vol. 5, Issue 2, 2016 · pp. 1–5 Read article
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In Vitro–In Vivo Correlation (IVIVC): A Strategic Tool in Drug Product Development
Abstract: In a recent era many concepts are dealing as an emerging tool for the drug delivery application like Biopharmaceutical Classification System (BCS), In vitro and In vivo study, and Bioavailability/Bioequivalence (BA/BE) study etc. To determine Therapeutic efficiency in vitro is not enough so the concept of In vitro-In vivo correlation (IVIVC) is playing as an convincing correlation with this for concept of pharmaceutical dosage forms have been a main focus …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 3, 2016 · pp. 31–54 Read article
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3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
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Swift Solutions: The Science and Innovation Behind Fast-Dissolving Tablets
Abstract: Swift solutions in the context of fast dissolving tablets (FDTs) represent an innovative breakthrough in pharmaceutical science, aiming to provide rapid and effective drug delivery for patients who face difficulty swallowing conventional dosage forms. The science and innovation behind FDTs are rooted in advanced formulation techniques, material science, and drug delivery mechanisms that prioritize speed, convenience, and patient compliance. These tablets are formulated to dissolve quickly in the mouth, removing …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 26–36 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
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Liquid Crystals as Novel Drug Carrier: A Review
Abstract: Liquid crystal is a thermodynamic stable phase characterized by anisotropic properties, generally lying in the temperature range between the solid and isotropic liquid phase, hence are termed mesophase. Based on the way that liquid crystals are obtained, they can be classified into two types—thermotropic liquid crystals and lyotropic liquid crystals. The thermotropic liquid crystal is generated by variation of temperature in the liquid state, while the lyotropic liquid crystal is …
Published in Trends in Drug Delivery · Vol. 2, Issue 1, 2015 · pp. 1–9 Read article
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RP-HPLC method for simultaneous determination of Drospirenone and Ethinylestradiol in Bulk and their Pharmaceutical dosage form
Abstract: Oral contraceptive is used to prevent the pregnancy which is contain hormones to block the release of eggs from the ovaries. Most of them contain estrogen and progesterone. Nowadays, usage of hormonal contraceptive is sharply enhancing; around 100 million of women worldwide are taking these drugs. With this drug fertility rate can be supressed as long as they want or plan their activity along with these drugs provide efficacy, reliability, …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 46–67 Read article
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Ethnomedicinal, Pharmacological and Phytochemical Screening of Supari (Areca catechu Linn.): A Review
Abstract: Supari (Areca catechu Linn.) is a tall tree about 10–20 m long. It is used both locally and internally. Local application is beneficial in various acute inflammatory conditions in the form of gargle, vaginal douche or abzan, decoction, juice and oil. Internally it act as muqavvie-qalb (cardiotonic) and muqavvi-e-ama (intestinal tonic), sozish meda (gastric irritation), dries the excessive secretions of mouth, used in vomiting and nausea, strengthen the teeth and …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 6–20 Read article
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Need of Standardization of Habb: A Unani Medicine
Abstract: Habb (pill) is a solid dosage form for oral administration of drugs in the human body. The present challenge for Unani scholars is to validate the claims made in the classical texts by applying scientific methodologies on this important dosage form. These claims need to be validated and the drugs need to be standardized on more precise scientific parameters. In order to have a good coordination between the quality of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 2, 2017 · pp. 37–45 Read article
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Protective Effects of Phellinus linteus Polysaccharides Against Radiation-Induced Hematopoietic Damage in Bone Marrow of Mice
Abstract: Chemotherapy and radiation therapy, which are standard methods of treatment for various cancers, often result in suppression of hematopoiesis accompanied by reduction in the number of hematopoietic stem cells and their progeny. We investigated a clinically potential use of Phellinus linteus polysaccharide in the treatment of various cytopenias induced by radiotherapy. Mice were administered Phellinus linteus polysaccharide orally at a dosage of 100 mg/kg once daily for + consecutive days, …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 12–17 Read article
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A Brief Review on Acne Vulgaris: Pathogenesis, Diagnosis and Treatment
Abstract: Acne vulgaris is one of the most common dermatological disorders that afflict people in their adolescence. Acne vulgaris or simply known as acne is a human skin disease characterized by skin with scaly red skin (seborrhea), blackheads and whiteheads (comedones), pinheads (papules), large papules (nodules), pimples and scarring. Acne vulgaris is a disease of pilosebaceous unit characterized by the formation of open and closed comedones, papules, pustules, nodules and cysts. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 3, 2014 · pp. 1–12 Read article
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A Study to assess Prescription pattern in outpatient department of tertiary care hospital
Abstract: ABSTRACTBackground:Antibiotic resistance and irrational prescribing is a global concern, is particularly pressing in developing nations, including India, where the burden of infectious disease is high and healthcare spending is low. The Global Antibiotic Resistance Partnership (GARP) was established to develop actionable policy recommendations specifically relevant to low- and middle-income countries where suboptimal access to antibiotics - not a major concern in high-income countries - is possibly as severe a problem …
Published in Journal of Nursing Science & Practice · Vol. 8, Issue 2, 2018 · pp. 33–36 Read article
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The Effect of Vitamin A Dose For Different Periods On The Spleen of White Rats: A Histological Study
Abstract: There are many detrimental effects of hypervitaminosis (A) on immune system function, growth, and reproduction. The main objective of the study was to evaluate the histological changes in the spleen of white rats given an excessive amount of vitamin A. The study was conducted from October 21, 2022, to December 12, 2022, at the College of Education's Animal House. (40) adult male albino rats, weighting between 200 and 220 grams …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 Read article
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Sublingual Drug Delivery System: An Update
Abstract: Oral transmucosal delivery, especially sublingual delivery, has progressed far beyond the use of traditional dosage forms with novel approaches emerging continuously. Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route, offering a vast number of advantages. Sublingual delivery tends to administer substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue, bypassing the …
Published in Trends in Drug Delivery · Vol. 3, Issue 3, 2016 · pp. 1–19 Read article
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Research and Industrial Insight: Toxicology
Abstract: Toxicology is a division of biology, chemistry, and medicine related with the study of the special effects of chemicals on breathing organisms. It also studies the injurious effects of chemical, biological and physical mediators in biological system that founds the degree of destruction in living organisms. The correlation between dose and its belongings on the exposed organism is of great importance in toxicology. A factor that inspires the chemical toxicity …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 36–40 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article
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Drugs and Polymers Used for Colon Specific Drug Delivery System with Current Trends: A Systematic Review
Abstract: Due to greater flexibility in design of dosage form and high patient compatibility, oral route of administration is the most preferred route but the gastrointestinal tract has many types of other undefeatable barriers to drug delivery. In oral colon-specific drug delivery system, colon has a large amount of lymphoma tissue which facilitates direct absorption into the blood, negligible brush border membrane activity, and much less pancreatic enzymatic activity as compared …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 4, Issue 3, 2013 · pp. 1–8 Read article