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20 articles for “cornea”
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Recent studies of Dermoids of cornea
Abstract: The most prevalent type of episcleralchoristomas are epibulbardermoids, which are birth abnormalities involving the globe caused by congenital overgrowth of normal tissues by collagenous connective tissue coated with epidermoid epithelium in an inappropriate place. These anomalies can appear on one or both sides, with the bulbar conjunctiva often containing the majority of these abnormalities (>85%). Corneal dermoids are an eye abnormality that can appear at any age, from infancy to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 3, 2023 · pp. 7–11 Read article
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Management of Corneal Foreign Body in a Dog
Abstract: A nine-year-old male dog presented with blepharospasm and epiphora in the right eye was diagnosed to have a penetrating corneal foreign body. As the dog was non-cooperative, it was decided to remove the foreign body under general anesthesia. The ocular cul-de-sac was irrigated with 0.5% povidone iodine solution under general anesthesia and the foreign body was removed carefully using a fine needle tip. The cornea was checked for its intactness …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 8, Issue 3, 2019 · pp. 1–2 Read article
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Dry Eye Disease: A Common Ophthalmic Problem
Abstract: Dry eye is a multifactorial disorder of tears and ocular surface caused due to unstable tear film giving rise to chronic dryness of cornea and conjunctiva. and in turn causes a feeling of dryness, foreign body sensation, pain, redness, burning, and light sensitivity. It can lead to serious complications like a corneal ulcer, which result in blindness if timely treatment is not given. The dry eye disease prevalence ranges up …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 2, 2022 · pp. 26–33 Read article
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Comparative Evaluation of Corneal Permeation of Indomethacin Using Different Vegetable Oil
Abstract: Topical administration of drugs is the most favoured route for management of ocular inflammation. About 90% of dose applied topically from such solutions is lost due to precorneal losses (nasolacrimal drainage) and tearing results in poor availability as contact time is less between drug and ocular tissue. An increased ocular contact time of the drug may be achieved by formulating the drug as an oil solution. In this study, invitro …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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Tarsorraphy in Buffalo Calves: Five Case Reports
Abstract: Corneal ulceration in animals gives challenge to the field veterinarians, because of its unresponsiveness to medical treatment. The present paper reports that tarsorraphy is the choice of treatment for unresponsive corneal ulceration in animals. Keywords: Corneal ulcer, buffalo calves, tarsorraphyCite this Article Thangamani A. Tarsorraphy in Buffalo Calves: Five Case Reports. Research & Reviews: Journal of Veterinary Science and Technology. 2017; 6(3): 7–8p.
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 6, Issue 3, 2017 · pp. 7–8 Read article
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Recent Trends in Ocular Drug Delivery: Challenges and Approaches
Abstract: Drug topically regulation can be accessed most easily in the eye. When given topically as eye drops, medication ocular bioavailability is quite low. Drug entry into specific ocular locations is complicated by the complex anatomy and physiology of the human eye. Research has long been interested in the topical administration of successful treatments. To provide a suitable ocular penetration and extend the duration of drug residence is their challenging task. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 22–38 Read article
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Emerging Trends in Photobiology: Exploring the Photophysics and Photobiology of the Eye
Abstract: The eye consists of three main segments: the cornea, lens, and retina. The primary function of the anterior ocular tissue, the cornea and lens, is to transmit and focus light onto the retina without distortion. They also filter UV light (under 400 nm), preventing it from reaching the retina. While light reaching the retina is mostly used for vision, it can also have various effects on the eye's constituents, both …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 31–37 Read article
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A Case Report on Alport Syndrome which ends up with Allograft Rejection due to Anti-GBM Disease
Abstract: Alport syndrome (AS) is a condition which is genetically inherited and is characterized by abnormalities in the basement membrane of the kidney, ear and eye as well. It is one of the spectra of diseases representing hereditary nephritis, which inevitably leads to end-stage renal disease (ESRD). Sensorineural hearing loss (SNHL) is also a characteristic feature in AS. The hearing abnormality begins during late childhood or early adolescence and 90% of …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 3, 2019 · pp. 1–4 Read article
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The Influence of the Yellow Sand on the Eyes of Experimental Animal
Abstract: The yellow sand is one of the phenomena of natural disasters often occurring in spring. In order to find out the influence on the eyes of the experimental animals by the yellow sand and its pathological histological findings, we went ahead with the research works. We used the yellow sand dust and non-yellow sand dust collected with the method of inhalation for the study materials and 100 rabbits breeded in …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 2, 2020 · pp. 36–40 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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An Automatic Upper/Dipper Light control circuit for vehicle
Abstract: A few vehicles on streets are expanding step by step, likewise, the innovation has grown however the wellbeing factor is constantly required to have been thought of. These days vehicles come warmed with loads of wellbeing highlights. One of the fundamental wellbeing highlights that should be introduced is a programmed upper scoop control of the fog light, this component can principally be utilized during evening driving. Natural eyes are extremely …
Published in Trends in Opto-electro & Optical Communication · Vol. 13, Issue 2, 2023 · pp. 25–31 Read article
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Effectiveness of STP on Knowledge and Attitude of Nursing Students on Eye Donation
Abstract: There are almost 52 million visually impaired people and 270,000 blind children in India. That's almost one-fourth the world's blind population living in India. Eye donation provides people who are blind with an opportunity to regain their vision through corneal transplantation, research and teaching. The need for donated eyes far exceeds the availability of donations. Nursing students are the future health care providers for the community. They are from different …
Published in Journal of Nursing Science & Practice · Vol. 5, Issue 1, 2015 · pp. 38–42 Read article
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Clinical Fusariosis in India: Taxonomy, Pathogenesis, and Therapeutic Challenges
Abstract: Fusarium species are emerging opportunistic pathogens in humans, responsible for a wide spectrum of infections ranging from superficial keratitis and onychomycosis to life-threatening disseminated disease in immunocompromised hosts. Historically regarded as plant pathogens and environmental saprophytes, these hyaline moulds have become clinically relevant with the increasing use of intensive chemotherapy, haematopoietic stemcell and solidorgan transplantation, and widespread use of broadspectrum antibiotics and corticosteroids. In India, Fusarium assumes particular importance due …
Published in International Journal of Pathogens · Vol. 3, Issue 2, 2026 Read article
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Effect of Quercetin against MES and PTZ-Induced Convulsions in Wistar Rats
Abstract: Besides its anti-oxidative effect, quercetin has shown to exert wide range of pharmacological effects. However, there is no experimental study on antiepileptic potential of quercetin. Hence, in the current study, the possible antiepileptic effect of quercetin has been evaluated against maximal electroshock seizure (MES) and PTZ-induced convulsions. Generalized tonic-clonic seizures are induced by applying current (150 mA, 0.2 s) through corneal electrodes using electroconvulsiometer. Absence seizures were induced by a …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 1, 2017 · pp. 9–13 Read article
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Atypical Traumatic Trigeminal Neuritis in a Labrador Retriever Dog: A Case Report
Abstract: AbstractAcute trigeminal neuritis of traumatic origin was diagnosed in a middle-aged Labrador retriever dog based on clinical signs, such as dropped jaw, loss of corneal reflex, drooling of saliva, etc. Certain symptoms, such as Horner’s syndrome, masticatory muscle atrophy, etc., were absent, while intact swallowing reflex, partial paralysis of tongue with lateral deviation were the atypical clinical signs. Complete recovery was observed within 45 days with supportive therapy and management …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 5, Issue 2, 2016 · pp. 12–15 Read article
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Evaluation of Anaesthetic Protocol for Zebrafish Embryo (Danio rerio): Lignocaine Combined with Diazepam and Ketamine with different doses Temperature Modulation
Abstract: Zebrafish (Danio rerio) model is economically viable and scientifically significant to identify several human diseases. It has genetic homology to humans (80-85%). Its other advantages are high reproductive success, embryo and larvae transparency and rapid development. Also compared to mammals, the maintenance cost of Zebrafish is lower. Ethyl 3-aminobenzoate methane sulfonate (MS-222) is known as the standard fish Anaesthetic and widely used in Zebrafish, but it can have adverse effects …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 2, 2020 · pp. 16–32 Read article
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Current Trends about Transfersomes: Formulations, Applications and Pharmacological Interventions.
Abstract: Transfersomes are one of the novel targeted drug delivery system which includes hydrophilic molecules. Transfersomes are a type of liposomes which consists of phosphodidylcholine and an edge activator. The elastic characteristics of Transfersomes enabling it to bend and penetrate through tiny holes that is much smaller than their own size. Transfersomes has various advantages like good solubility, greater bioavailability, and better penetration through the stratum cornea through intracellular route or …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 1, 2023 · pp. 10–26 Read article
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Ocular Inserts: An Overview
Abstract: Ocular inserts are sterile preparations which are to be placed into cul-de-sac or conjuctival sac. The major aim of ocular insert is to maintain a therapeutic level at the site of action for prolonged period of time. The therapeutic efficacy of an ocular drug can be greatly improved by prolonging its contact with the corneal surface. Ocular insert gives several advantages like increased ocular residence time, drug release at a …
Published in Trends in Drug Delivery · Vol. 4, Issue 2, 2017 · pp. 20–22 Read article
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Preservatives for Ocular Drug Delivery System
Abstract: Most challenge faced today is in ocular drug delivery. Topical eye drop is the most convenient and patient compliant route of drug administration, especially for the treatment of anterior segment diseases. Delivery of drugs to the targeted ocular tissues is restricted by various precorneal, dynamic and static ocular barriers. Also, therapeutic drug levels are not maintained for longer duration in target tissues. In the past two decades, ocular drug delivery …
Published in Trends in Drug Delivery · Vol. 7, Issue 3, 2020 · pp. 1–5 Read article
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Maximizing In Situ Formulation Adhesion Potential By Testing Different Polymer
Abstract: This study explores the use of a in-situ ocular gel delivery system for gentamicin sulphate. The anatomy of human eye consists of the cornea, lens, aqueous humor, vitreous humor, and retina. The physiology of the human eye involves the production of tears and the process of accommodation. Eye infections are caused by viruses, fungi, bacteria, or parasites. The symptoms of eye infection can include redness, itching, burning, watering, discharge, and …
Published in Trends in Drug Delivery · Vol. 10, Issue 1, 2023 · pp. 1–10 Read article