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58 articles for “Randomized control trials”
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Coronary Risk Reduction Discharge Training Programme (CRR-DTP) on Selfcare Behaviour Among Patients with Percutaneous Coronary Intervention (PCI): A Randomized Controlled Trial
Abstract: AbstractObjective: The study was conducted with an objective to assess the effectiveness of coronary risk reduction discharge training programme (CRR-DTP) on self-care behaviour among patients with percutaneous coronary intervention (PCI). Methods: A randomized control trial was conducted in Jan 2017 in HDHI, Ludhiana. 60 patients were selected on the basis of convenience sampling technique and randomly allocated to experimental (30) and control group (30). Coronary risk reduction discharge training programme …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 2, 2020 · pp. 41–49 Read article
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Evaluation of Efficacy of Hulba (Trigonellafoenumgraecum Linn.) in Rheumatoid Arthritis: A Randomized Control Trial
Abstract: The prevalence of the disease is approximately 0.5–1%. Rheumatoid arthritis has a large impact on patient’s quality of life and it has also been associated with a reduced life expectancy. Therefore, the study was conducted to evaluate the efficacy of Tukhm Hulba (Trigonellafoenumgraecum Linn.) in the management of rheumatoid arthritis. The study was carried out as a single, blind, randomized and standard controlled trial, to evaluate the efficacy of Tukhme …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 3, 2016 · pp. 27–34 Read article
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The Effectiveness of Honey Application for Oral Mucositis in Cancer Patients: A Review of Randomized Controlled Trials
Abstract: Background: Oral mucositis (OM) is a prevalent and distressing adverse outcome of cancer therapies, including chemotherapy and radiation therapy. It is an inflammatory ailment that impacts the mucous membrane inside the mouth, tongue, gums, and throat. OM can cause pain, discomfort, difficulty swallowing, and in severe cases, it can lead to infection and delayed cancer treatment. Although there are various treatments available, such as painkillers, anti-inflammatory drugs, and topical anesthetics, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 32–39 Read article
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Examining the Impact of a Nurse Navigator Program on Anxiety, Psychological Well-being, and Quality of Life in Breast Cancer Patients at a Tertiary Care Hospital in Haryana: A Randomized Controlled Trial
Abstract: Background of study: Breast cancer stands as the leading cancer type affecting women and remains a significant contributor to female mortality. It is a complex ailment influenced by multiple factors. Globally, in 2020, approximately 2.3 million women received diagnoses of breast cancer, resulting in 685,000 fatalities. This condition can profoundly impact various aspects of a person's existence, encompassing physical, psychological, emotional, social, and familial spheres. A notable observation is the …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 31–39 Read article
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Effect of 940-nm Low-Level Laser Therapy on Tooth Movement Rate during Orthodontic Treatment: A Split-Mouth Double-Blind Randomized-Controlled Trial
Abstract: This study aimed to evaluate the effect of low-level laser with wavelength of 940 nm on acceleration of orthodontic tooth movement. Materials and Methods: This study was a double-blind randomized-controlled trial with split-mouth design. Fifty-five patients whose four first premolars were extracted for orthodontic treatment were randomly allocated to group A (n = 27) and group B (n = 28). Canine retraction was performed using the force of 150 g …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 3, 2024 · pp. 14–20 Read article
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Effectiveness of an Intervention on Nurse’s and Caregiver’s Knowledge and Practices Regarding Chemotherapy Induced Neutropenic Complications: A Cluster Randomized Controlled Trial
Abstract: Abstract Objective: To assess the effectiveness of an intervention on knowledge and practices of nurses and caregivers regarding chemotherapy induced neutropenic complications. Methods: A total of 51 nurses and 105 patients and their caregivers were enrolled in the study using cluster randomization. 27 nurses and 51 patient’s and their caregiver’s were enrolled in control group from radiotherapy department and 24 nurses and 54 each patients and their caregivers were enrolled …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 2, 2020 · pp. 18–24 Read article
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Effect of Saline Instillation during Endotracheal Tube Suctioning on Oxygen Saturation and Heart Rate: A Randomized Control Trial
Abstract: Normal saline instillation during endotracheal suctioning is a widely used practice in most of the hospitals but there is inconsistency and controversy regarding use of saline. This study aims to find effect of sterile isotonic normal saline instillation during endotracheal suctioning on oxygen saturation and heart rate. Total of 150 patients on mechanical ventilation were selected by total enumerative sampling technique and were then randomized into three groups: (1) Control …
Published in Journal of Nursing Science & Practice · Vol. 4, Issue 3, 2014 · pp. 49–55 Read article
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Sudarshan Kriya Intervention and Rise of Protective Prostaglandins in Advanced-Stage Breast Cancer: Double-Blind, Randomized, Controlled Trial
Abstract: Background: Breast cancer patients in advanced stages of cancer are managed by palliative care. This study reports important prostaglandin changes observed with added intervention of Sudarshan Kriya in their ongoing palliative care. Level of Prostaglandin A₂ (PGA₂) indicates tumor growth suppression; its level rises if person’s general condition is good, physically fit and active while PGE₂ and D₂ are considered pro-inflammatory. Quantitative assessment of Prostaglandins was done pre and post …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 62–68 Read article
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Effectiveness of communication chart on patient satisfaction among conscious intubated patients: A randomized controlled trial
Abstract: OBJECTIVESLack of communication among intubated patient frequently described in literature as major problem. The main thrust of the study is to evaluate the effectiveness of communication chart in improving patient satisfaction among conscious intubated patients.METHODSRandomized control design was employed using non-replacement lottery method to allocate 30 subjects in each control and experimental group. Ethical approval was obtained by the Ethics Review Committee of hospital. Data were collected at pre-intervention and …
Published in Journal of Nursing Science & Practice · Vol. 8, Issue 3, 2018 · pp. 15–23 Read article
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Evaluating Ma-ul-Shae’er (Barley Water) as a Nutritional Supplement in Pulmonary Tuberculosis: A Randomised Controlled Trial
Abstract: Background: Tuberculosis (TB) stands as a persistent global health challenge, imposing significant burdens on societies across the world. Despite its profound medical, social, and economic implications, there exists a critical gap in understanding interventions that could improve the quality of life for individuals afflicted by TB.Objective: This study aims to fill this void by investigating the impact of barley water on the quality of life of TB patients, providing a …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 3, 2023 · pp. 29–38 Read article
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Impact of Pre-Operative Nebulized Lidocaine–Dexmedetomidine Combination Versus Monotherapy on Incidence, Severity, and Patient Comfort Scores of Post-Operative Sore Throat: A Randomized Controlled Clinical Trial
Abstract: Post-operative sore throat (POST) is a common issue after endotracheal intubation and can reduce patient comfort and hinder recovery. This randomized, double-blind clinical study investigated how effective pre-operative nebulized lidocaine, dexmedetomidine, and their combination are in minimizing POST. Eligible adult patients classified as ASA I–II and scheduled for elective surgery under general anesthesia were randomly assigned to three groups. Nebulization was administered 15–20 minutes before induction using standardized dosing and …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 29–35 Read article
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Caries-Preventive Effects of Self-Applied Subacidic 0.5% NaF-HF Gel via Toothbrushing in 7–8-Year-Old Schoolchildren: A Randomized Controlled Clinical Trial
Abstract: To assess the caries-preventive effectiveness of self-applied subacidic 0.5% sodium fluoride–hydrofluoric acid (NaF-HF) gel used during toothbrushing in children aged 7–8 years Objective: To assess the caries-preventive effectiveness of self-applied subacidic 0.5% sodium fluoride–hydrofluoric acid (NaF-HF) gel used during toothbrushing in children aged 7–8 years. Methods: This 1-year, multi-arm, double-blind, placebo-controlled, parallel-group randomized study evaluated the caries-preventive efficacy of self-applied 0.5% NaF-HF gel among primary schoolchildren. A total of 1200 …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 14–19 Read article
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Randomized Placebo Controlled Trial Comparing the Efficacy of Satawar (Asparagus racemosus) & Zeera sufaid (Cuminum cyminum) in Qillat-ul-laban (Oligogalactia)
Abstract: A state when the production of milk in lactating mother is too scanty to be sufficient for the infant is called “Oligogalactia”. Its prevalence is 45–53.6% in India and is increasing nowadays. Present study was aimed to see the efficacy of satawar and zeera sufaid for improvement in lactation in the patients of oligogalactia. In this prospective randomized controlled trial, all apparently normal mothers delivered a single full term baby …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 4, Issue 1, 2017 · pp. 39–44 Read article
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Exploring the Connection between Mindfulness and Alzheimer's Disease/Parkinson's Disease: A Systematic Review and Meta-Analysis.
Abstract: Alzheimer's disease and Parkinson's disease have serious effects on patients and their families, yet there are no known treatments to slow the progression of these diseases. Non-pharmacological treatments for these problems, like yoga and meditation, have begun to gain popularity. The purpose of this meta-analysis and systematic review was to examine the relationship between yoga and mindfulness meditation and Alzheimer's and Parkinson's disease, as well as their potential to help …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 2, 2023 · pp. 1–9 Read article
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Prospective Evaluation of the Optimal Concentration and Effect of Epinephrine as an Adjuvant to Local Anesthetics for Prolonging Block Duration and Reducing Systemic Toxicity in Outpatient Surgery
Abstract: Purpose: To evaluate the optimal concentration and effect of epinephrine as an adjuvant to local anesthetics for prolonging block duration and reducing systemic toxicity in outpatient surgery. Methods: The study involved a randomized double-blind clinical trial on 80 adult patients awaiting day-care extremity surgery. The patients were randomly assigned to two groups of equal size. One group, Group E, was given the local anesthetic agent along with epinephrine as an …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 64–69 Read article
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Comparison Of Postoperative Sore Throat Following Endotracheal Intubation With Or Without Water Based Lubricating Jelly
Abstract: Background: Water-soluble lubricant gel (X-Y jelly) was evaluated for its ability to lessen the common throat pain that follows tracheal intubation under general anesthesia. Materials and Methods: scheduled for elective surgery under general anesthesia requiring endotracheal intubation, Were enrolled in a prospective, randomized, double-blind comparative study. They were split evenly into two -member cohorts. One cohort received 3 mL of water-soluble X-Y gel smeared from the cuff tip to 15 …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 1–7 Read article
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Significance of Randomized Clinical Trials
Abstract: The most exacting and reliable research tool for determining if there is a cause-and-effect relationship between an intervention and a result is the randomized controlled trial. When assessing the efficacy and safety of an intervention, a randomized controlled trial can produce high-quality evidence. Every randomized controlled trial (RCT) ought to have predetermined primary outcomes, be registered with a clinical trials database, and possess the necessary ethical permissions. The quality of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 3, 2023 · pp. 12–16 Read article
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Progressive Muscle Relaxation and Anxiety Reduction among Cardiac Surgery Patients
Abstract: Heart surgery is a stressful life event. Progressive muscle relaxation (PMR) can be implementing in nursing practice as an effective, complimentary therapy. Present study was undertaken with the objective of assessing the effect of PMR on anxiety level of valvular heart surgery patients. A randomized controlled trial was done and 65 adult patients were enrolled and randomly assigned 33 into the experimental group and 32 into control group. Hamilton anxiety …
Published in Journal of Nursing Science & Practice · Vol. 8, Issue 3, 2018 · pp. 38–47 Read article
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Nanocrystalline Silver–Carbon
Abstract: This study is on the properties of nanocrystalline silver products and examines on the internal relation between silver and carbon particles. Nanocrystalline utilizes nanotechnology to release nanocrystalline silver crystals. Nanocrystalline releases 60 times fewer silver cations than silver–carbon interaction in between strongly. Silver impregnated fast releases dressings release minute concentrations of silver which are quickly bounds up by the chloride in the wound exudates. The silver and carbon ions are …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 2, 2018 · pp. 27–29 Read article
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Comparison of Intravenous Lignocaine and Esmolol in Attenuating Hemodynamic Response to Laryngoscopy and Endotracheal Intubation
Abstract: Objective: This study aimed to evaluate the effectiveness of intravenous lignocaine versus esmolol in minimizing the hemodynamic response during laryngoscopy and intubation. Methods: This prospective, randomized controlled trial included patients scheduled for elective surgery under general anesthesia. Participants were randomly allocated to receive either intravenous lignocaine (Group L) or esmolol (Group E) prior to induction. Hemodynamic parameters—such as heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 3, 2024 · pp. 29–44 Read article